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Jennifer Gjerde

Postdoctoral fellow
  • E-mailJennifer.Gjerde@uib.no
  • Phone+47 55 97 43 98
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
  • Postal Address
    Postboks 7804
    5020 Bergen
Journal articles
  • Helland, Thomas; Hagen, Kari Britt; Haugstøyl, Martha Eimstad; Kvaløy, Jan Terje; Lunde, Siri; Lode, Kirsten; Lind, Ragna Anne; Gripsrud, Birgitta Haga; Jonsdottir, Kristin; Gjerde, Jennifer; Bifulco, Ersilia; Hustad, Simon Steinar; Jonassen, Janne; Aas, Turid; Lende, Tone Hoel; Lien, Ernst Asbjørn; Janssen, Emiel; Søiland, Håvard; Mellgren, Gunnar. 2019. Drug monitoring of tamoxifen metabolites predicts vaginal dryness and verifies a low discontinuation rate from the Norwegian Prescription Database. Breast Cancer Research and Treatment. 177: 185-195. doi: 10.1007/s10549-019-05294-w
  • Johansson, Harriet; Aristarco, Valentina; Gandini, Sara; Gjerde, Jennifer; Macis, Debora; Guerrieri-Gonzaga, Aliana; Serrano, Davide; Lazzeroni, Matteo; Rajasekaran, Agnita; Williard, Clark V.; Mellgren, Gunnar; DeCensi, Andrea; Bonanni, Bernardo. 2019. Prognostic impact of genetic variants of CYP19A1 and UGT2B17 in a randomized trial for endocrine-responsive postmenopausal breast cancer. The Pharmacogenomics Journal. 1-8. doi: 10.1038/s41397-019-0087-z
  • Johansson, Harriet; Gandini, Sara; Serrano, Davide; Gjerde, Jennifer; Lattanzi, Monia; Macis, Debora; Guerrieri-Gonzaga, Aliana; Aristarco, Valentina; Mellgren, Gunnar; Lien, Ernst Asbjørn; Decensi, Andrea; Bonanni, Bernardo. 2016. A pooled analysis of CYP2D6 genotype in breast cancer prevention trials of low-dose tamoxifen. Breast Cancer Research and Treatment. 159: 97-108. doi: 10.1007/s10549-016-3932-7
  • Flågeng, Marianne Hauglid; Knappskog, Stian; Gjerde, Jennifer; Lønning, Per Eystein; Mellgren, Gunnar. 2015. Estrogens correlate with PELP1 expression in ER positive breast cancer. PLoS ONE. 10:e0134351. 12 pages. doi: 10.1371/journal.pone.0134351
  • Helland, Thomas; Gjerde, Jennifer; Dankel, Simon N; Fenne, Ingvild Sveinsgjerd; Skartveit, Linn; Drangevåg, Andreas; Bozickovic, Olivera; Flågeng, Marianne Hauglid; Søiland, Håvard; Mellgren, Gunnar; Lien, Ernst Asbjørn. 2015. The active tamoxifen metabolite endoxifen (4OHNDtam) strongly down-regulates cytokeratin 6 (CK6) in MCF-7 breast cancer cells. PLoS ONE. 10. 19 pages. doi: 10.1371/journal.pone.0122339
  • Bjørndal, Bodil; Strand, Elin; Gjerde, Jennifer; Bohov, Pavol; Svardal, Asbjørn M.; Diehl, Bernd W.K.; Innis, Sheila M.; Berger, Alvin; Berge, Rolf Kristian. 2014. Phospholipids from herring roe improve plasma lipids and glucose tolerance in healthy, young adults. Lipids in Health and Disease. 13:82. doi: 10.1186/1476-511X-13-82
  • Hagen, Kari Britt; Aas, Turid; Lode, Kirsten; Gjerde, Jennifer; Lien, Ernst Asbjørn; Kvaløy, Jan Terje; Lash, Timothy L; Søiland, Håvard; Lind, Ragna Anne. 2014. Illness uncertainty in breast cancer patients: Validation of the 5-item short form of the Mishel Uncertainty in Illness Scale. European Journal of Oncology Nursing. 1-7. doi: 10.1016/j.ejon.2014.10.009
  • Lien, Ernst Asbjørn; Søiland, Håvard; Gjerde, Jennifer. 2013. Associations between tamoxifen and age during steady state tamoxifen treatment of postmenopausal women with breast cancer. Experimental and clinical endocrinology & diabetes. 121. 1 pages. doi: 10.1055/s-0033-1336763
  • Lien, Ernst Asbjørn; Søiland, Håvard; Lundgren, Steinar; Aas, Turid; Steen, Vidar Martin; Mellgren, Gunnar; Gjerde, Jennifer. 2013. Serum concentrations of tamoxifen and its metabolites increase with age during steady-state treatment. Breast Cancer Research and Treatment. 141: 243-248. doi: 10.1007/s10549-013-2677-9
  • Methlie, Paal; Dankel, Simon E Nitter; Myhra, Tone Sæterdal; Christensen, Bjørn Jostein; Gjerde, Jennifer; Fadnes, Dag Jone Stokke; Våge, Villy; Løvås, Kristian; Mellgren, Gunnar. 2013. Changes in adipose glucocorticoid metabolism before and after bariatric surgery assessed by direct hormone measurements. Obesity. 21: 2495-2503. doi: 10.1002/oby.20449
  • Serrano, Davide; Lazzeroni, Matteo; Gandini, Sara; Macis, Debora; Johansson, Harriet; Gjerde, Jennifer; Lien, Ernst Asbjørn; Feroce, Irene; Pruneri, Giancarlo; Sandri, Maria T; Bassi, Fabio; Brenelli, Fabricio; Luini, Alberto; Cazzaniga, Massimiliano; Varricchio, Clara; Guerrieri-Gonzaga, Aliana; Decensi, Andrea; Bonanni, Bernardo. 2013. A randomized phase II presurgical trial of weekly low-dose tamoxifen versus raloxifene versus placebo in premenopausal women with estrogen receptor-positive breast cancer. Breast Cancer Research. 15. 11 pages. doi: 10.1186/bcr3439
  • Søiland, Håvard; Hagen, Kari Britt; Gjerde, Jennifer; Lende, Tone Hoel; Lien, Ernst Asbjørn. 2013. Breaking away: High fracture rates may merit a new trial of adjuvant endocrine therapy in Scandinavian breast cancer patients. Acta Oncologica. 52: 861-U216. doi: 10.3109/0284186X.2012.742963
  • Gjerde, Jennifer; Gandini, Sara; Guerrieri-Gonzaga, Aliana; Moi, Line Leonore Haugan; Aristarco, Valentina; Mellgren, Gunnar; Decensi, Andrea; Lien, Ernst Asbjørn. 2012. Tissue distribution of 4-hydroxy-N-desmethyltamoxifen and tamoxifen-N-oxide. Breast Cancer Research and Treatment. 134: 693-700. doi: 10.1007/s10549-012-2074-9
  • Moi, Line Leonore Haugan; Flågeng, Marianne Hauglid; Gjerde, Jennifer; Madsen, Andre Greger; Røst, Therese Halvorsen; Gudbrandsen, Oddrun Anita; Lien, Ernst Asbjørn; Mellgren, Gunnar. 2012. Steroid receptor coactivators, HER-2 and HER-3 expression is stimulated by tamoxifen treatment in DMBA-induced breast cancer. BMC Cancer. 12. 12 pages. doi: 10.1186/1471-2407-12-247
  • Veum, Vivian Lohmann; Dankel, Simon E Nitter; Gjerde, Jennifer; Nielsen, Hans Jørgen; Solsvik, Margit Hildershavn; Haugen, Christine; Christensen, Bjørn Jostein; Hoang, Tuyen; Fadnes, Dag Jone Stokke; Busch, Christian; Våge, Villy; Sagen, Jørn V.; Mellgren, Gunnar. 2012. The nuclear receptors NUR77, NURR1 and NOR1 in obesity and during fat loss. International Journal of Obesity. 36: 1195-1202. doi: 10.1038/ijo.2011.240
  • Ahern, Thomas P.; Christensen, Mariann; Cronin-Fenton, Deirdre P.; Lunetta, Kathryn L.; Søiland, Håvard; Gjerde, Jennifer; Garne, Jens Peter; Rosenberg, Carol L.; Silliman, Rebecca A.; Sørensen, Henrik Toft; Lash, Timothy L.; Hamilton-Dutoit, Stephen. 2011. Functional polymorphisms in UDP-glucuronosyltransferases and recurrence in tamoxifen-treated breast cancer survivors. Cancer Epidemiology, Biomarkers and Prevention. 20: 1937-1943. Published 2011-07-12. doi: 10.1158/1055-9965.EPI-11-0419
  • Serrano, Davide; Lazzeroni, Matteo; Zambon, Carlo–Federico; Macis, Debora; Maisonneuve, Patrick; Johansson, Harriet Ann; Guerrieri-Gonzaga, Aliana; Plebani, Mario; Basso, Daniela; Gjerde, Jennifer; Mellgren, Gunnar; Rotmensz, Nicole; Decensi, Andrea; Bonanni, Bernardo. 2011. Efficacy of tamoxifen based on cytochrome P450 2D6, CYP2C19 and SULT1A1 genotype in the Italian Tamoxifen Prevention Trial. The Pharmacogenomics Journal. 11: 100-107. doi: 10.1038/tpj.2010.17
  • Gjerde, Jennifer; Geisler, Jürgen; Lundgren, Steinar; Ekse, Dagfinn; Varhaug, Jan Erik; Mellgren, Gunnar; Steen, Vidar Martin; Lien, Ernst Asbjørn. 2010. Associations between tamoxifen, estrogens, and FSH serum levels during steady state tamoxifen treatment of postmenopausal women with breast cancer. BMC Cancer. 10. 13 pages. doi: 10.1186/1471-2407-10-313
  • Gjerde, Jennifer; Geisler, Jürgen; Lundgren, Steinar; Ekse, Dagfinn; Varhaug, Jan Erik; Mellgren, Gunnar; Steen, Vidar Martin; Lien, Ernst Asbjørn. 2010. Effects of CYP2C19 genotype on tamoxifen and estrogen metabolism. European Journal of Cancer. 8: 60-60.
  • Moi, Line Leonore Haugan; Flågeng, Marianne Hauglid; Gandini, Sara; Guerrieri-Gonzaga, Aliana; Bonanni, Bernardo; Lazzeroni, Matteo; Gjerde, Jennifer; Lien, Ernst Asbjørn; De Censi, Andrea; Mellgren, Gunnar. 2010. Effect of low-dose tamoxifen on steroid receptor coactivator 3/amplified in breast cancer 1 in normal and malignant human breast tissue. Clinical Cancer Research. 16: 2176-2186. doi: 10.1158/1078-0432.CCR-09-1859
  • Gjerde, Jennifer Fernandez; Geisler, Jurgen; Lundgren, Steinar; Ekse, Dagfinn; Breilid, Harald; Hauglid, Marianne; Hauglid, M; Varhaug, EJ; Varhaug, Jan Erik; Steen, Vidar Martin; Lønning, Per Eystein; Lonning, PE; Lien, Ernst Asbjørn. 2008. A study of associations between estrogen and tamoxifen metabolism, cytochrome 2D6 and sulfotransferase 1A1 polymorphisms, and sulfotransferase 1A1 gene copy number during steady state tamoxifen treatment. Breast Cancer Research and Treatment. 109: 592-592.
  • Gjerde, Jennifer Fernandez; Hauglid, Marianne; Hauglid, M; Breilid, Harald; Lundgren, S.; Varhaug, Jan Erik; Kisanga, Elton Richard; Mellgren, Gunnar; Steen, Vidar Martin; Lien, Ernst Asbjørn. 2008. Effects of CYP2D6 and SULT1A1 genotypes including SULT1A1 gene copy number on tamoxifen metabolism. Annals of Oncology. 19: 56-61. doi: 10.1093/annonc/mdm434
  • Karimian, Elham; Chagin, Andrei S; Gjerde, Jennifer Fernandez; Heino, Terhi; Lien, Ernst Asbjørn; Ohlsson, Claes; Sävendahl, Lars. 2008. Tamoxifen impairs both longitudinal and cortical bone growth in young male rats. Journal of Bone and Mineral Research. 23: 1267-1277. doi: 10.1359/JBMR.080319
  • Decensi, Andrea; Gandini, Sara; Serrano, Davide; Cazzaniga, Massimiliano; Pizzamiglio, Maria; Maffini, Fausto; Pelosi, Giuseppe; Daldoss, Christina; Omodei, Umberto; Johansson, Harriet; Macis, Debora; Lazzeroni, Matteo; Penotti, Mauro; Sironi, Laura; Moroni, Simona; Bianco, Vanda; Rondanina, Gabriella; Gjerde, Jennifer Fernandez; Guerrieri-Gonzaga, Aliana; Bonanni, Bernardo. 2007. Randomized dose-ranging trial of tamoxifen at low doses in hormone replacement therapy users. Journal of Clinical Oncology. 25: 4201-4209. doi: 10.1200/JCO.2006.09.4318
  • Gjerde, Jennifer Fernandez; Geisler, Jurgen; Lundgren, Steinar; Ekse, Dagfinn; Breilid, Harald; Hauglid, Marianne; Varhaug, Jan Erik; Mellgren, Gunnar; Steen, Vidar Martin; Lønning, Per Eystein; Lien, Ernst Asbjørn. 2007. A study of associations between estrogen and tamoxifen metabolism, cytochrome 2D6 and sulfotransferase 1A1 polymorphisms, and sulfotransferase 1A1 gene copy number during steady state tamoxifen treatment. Breast Cancer Research and Treatment. S106.
  • Gjerde, Jennifer Fernandez; Hauglid, Marianne; Breilid, Harald; Lundgren, Steinar; Varhaug, Jan Erik; Kisanga, Elton Richard; Mellgren, Gunnar; Steen, Vidar Martin; Lien, Ernst Asbjørn. 2007. Effect of CYP2D6 and SULT1A1 genotypes on the serum concentration of 4-hydroxytamoxifen and 4-hydroxy-N-demethyltamoxifen during steady state treatment of breast cancer patients. Breast. 16: S15-S15.
  • Gjerde, Jennifer; Geisler, Jurgen; Lundgren, Steinar; Ekse, Dagfinn; Breilid, H; Hauglid, M; Varhaug, Jan Erik; Mellgren, G; Steen, VM; Lønning, Per Eystein; Lien, Ernst A. 2007. A study of association between estrogen and tamoxifen metabolism, cytochrome 2D6 and sulfotransferae 1A1 polymorphisms, and sulfotransferase 1A1 gene copy number during steady sate tamoxifen treatment. Breast Cancer Research and Treatment. 106: S144-S144. Published 2007-10-24. doi: 10.1007/s10549-007-9793-3
  • Schjøtt, Jan; Gjerde, Jennifer; Kisanga, Elton Richard; Lien, Ernst Asbjørn. 2006. Pretreatment with tamoxifen does not change acute epirubicin cardiotoxicity in rats. Basic & Clinical Pharmacology & Toxicology. 98: 231-234. doi: Se sammendrag
  • Gjerde, Jennifer Fernandez; Hauglid, Marianne; Breilid, Harald; Lundgren, Steinar; Varhaug, Jan Erik; Kisanga, Elton Richard; Mellgren, Gunnar; Steen, Vidar Martin; Lien, Ernst Asbjørn. 2005. Relationship between CYP2D6 and SULT1A1 genotypes and serum concentrations of tamoxifen and its metabolites during steady state treatment in breast cancer patients. Breast Cancer Research and Treatment. 94: S236-S237.
  • Gjerde, Jennifer Fernandez; Kisanga, Elton Richard; Hauglid, Marianne; Holm, Pål Ivar; Mellgren, Gunnar; Lien, Ernst Asbjørn. 2005. Identification and quantification of tamoxifen and four metabolites in serum by liquid chromatography-tandem mass spectrometry. Journal of Chromatography A. 1082: 6-14. doi: 10.1016/j.chroma.2005.01.004
  • Kisanga, Elton Richard; Moi, Line Leonore Haugan; Gjerde, Jennifer; Mellgren, Gunnar; Lien, Ernst Asbjørn. 2005. Induction of hepatic drug-metabolising enzymes and tamoxifen metabolite profile in relation to administration route during low-dose treatment in nude rats. Journal of Steroid Biochemistry and Molecular Biology. 94: 489-498. doi: 10.1016/j.jsbmb.2004.12.037
  • Kisanga, Elton Richard; Gjerde, Jennifer; Guerrieri-gonzaga, Aliana; Pigatto, Francesca; Pesci - feltri, Adriana; Robertson, Chris; Serrano, Davide; Pelosi, Giuseppe; Decensi, Andrea; Lien, Ernst Asbjørn. 2004. Tamoxifen and metabolite concentrations in serum and breast cancer tissue during three dose regimens in randomized preoperative trial. Clinical Cancer Research. 10: 2336-2343.
  • Kisanga, Elton Richard; Gjerde, Jennifer; Schjøtt, Jan; Mellgren, Gunnar; Lien, Ernst Asbjørn. 2003. Tamoxifen administration and metabolism in nude mice and nude rats. Journal of Steroid Biochemistry and Molecular Biology. 84: 361-367.
Reports and theses
  • Gjerde, Jennifer. 2008. Tamoxifen treatment of breast cancer: Pharmacogenetics and therapeutic drug monitoring. 119 pages.
Book sections
  • Aas, Grete Hansen; Strand, Elin; Gjerde, Jennifer; Røsvik, Anne Synnøve; Sæbø, Per Christian; Bjørndal, Bodil. 2018. Effect of Whey and Herring Roe Protein administered as a supplement to young healthy adults – A pilot study. Chapter 9. In:
    • Akslen-Hoel, Linn Kristin; Thu, Beate Julie. 2018. Blue Growth: Aquaculture, Fisheries, Market and Health Perspectives. Orkana Forlag. 176 pages. ISBN: 978-82-8104-347-3.
  • Gjerde, Jennifer; Moi, Line Leonore Haugan; Mellgren, Gunnar; Lien, Ernst Asbjørn. 2012. Tamoxifen metabolism and biological activity. chapter 2, pages 7-28. In:
    • de Mello, R.A. 2012. Tamoxifen concepts and cancer: New paradigms. 196 pages. ISBN: 978-1-62081-520-5.
  • Moi, Line Leonore Haugan; Flågeng, Marianne Hauglid; Dankel, Simon E Nitter; Hoang, Tuyen; Gjerde, Jennifer; Sagen, Jørn V.; Lien, Ernst Asbjørn; Mellgren, Gunnar. 2011. Steroid Receptor Coactivators and Endocrine Treatment in Breast Cancer. 2, pages 35-66. In:
    • Bates, Margaret K; Kerr, Regina M. 2011. Nuclear Receptors. Nova Science Publishers, Inc.. 174 pages. ISBN: 978-1-61209-980-4.
  • Moi, Line Leonore Haugan; Flågeng, Marianne Hauglid; Fenne, Ingvild Sveinsgjerd; Gjerde, Jennifer; Lien, Ernst Asbjørn; Mellgren, Gunnar. 2011. Steroid Receptor Coactivators and Their Expression, Regulation and Functional Role in Endocrine Responsive and Resistant Breast Cancer. 35, pages 715-732. In:
    • Gunduz, Mehmet; Gunduz, Esra. 2011. Breast Cancer - Carcinogenesis, Cell Growth and Signalling Pathways. INTECH. 732 pages. ISBN: 978-953-307-714-7.

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