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  • E-mailJorn.Sagen@uib.no
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    Haukeland universitetssykehus, Laboratoriebygget
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    Postboks 7804
    5020 Bergen
Academic article
  • Bjune, Jan-Inge; Dyer, Laurence; Røsland, Gro Vatne; Tronstad, Karl Johan; Njølstad, Pål Rasmus; Sagen, Jørn V.; Dankel, Simon N; Mellgren, Gunnar. 2019. The homeobox factor Irx3 maintains adipogenic identity. Metabolism: Clinical and Experimental.
  • Dankel, Simon N; Røst, Therese Halvorsen; Kulyté, Agné; Fandalyuk, Zinayida; Skurk, Thomas; Hauner, Hans; Sagen, Jørn V.; Rydén, Mikael; Arner, Peter; Mellgren, Gunnar. 2019. The Rho GTPase RND3 regulates adipocyte lipolysis. Metabolism: Clinical and Experimental. 1-12.
  • Madsen, Andre; Oehme, Ninnie; Roelants, Mathieu; Bruserud, Ingvild Særvold; Eide, Geir Egil; Viste, Kristin; Bjerknes, Robert; Almås, Bjørg; Rosendahl, Karen; Sagen, Jørn V.; Mellgren, Gunnar; Juliusson, Petur Benedikt. 2019. Testicular ultrasound to stratify hormone references in a cross-sectional Norwegian study of male puberty. Journal of Clinical Endocrinology and Metabolism. 27 pages.
  • Gudbrandsen, Oddrun Anita; Dankel, Simon N; Skumsnes, Lillian; Flølo, Tone Nygaard; Folkestad, Oddry H; Nielsen, Hans Jørgen; Våge, Villy; Mohn, Arne-Christian; Nedrebø, Bjørn Gunnar; Sagen, Jørn V.; Fernø, Johan; Mellgren, Gunnar. 2019. Short-term effects of Vertical sleeve gastrectomy and Roux-en-Y gastric bypass on glucose homeostasis. Scientific Reports. 1-7.
  • Helgeland, Øyvind; Vaudel, Marc; Juliusson, Petur Benedikt; Holmen, Oddgeir Lingaas; Juodakis, Julius; Bacelis, Jonas; Jacobsson, Bo; Lindekleiv, Haakon; Hveem, Kristian; Lie, Rolv T.; Knudsen, Gun Peggy Strømstad; Stoltenberg, Camilla; Magnus, Per; Sagen, Jørn V.; Molven, Anders; Johansson, Stefan; Njølstad, Pål Rasmus. 2019. Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth. Nature Communications. 1-10.
  • Svärd, Jessica; Røst, Therese Halvorsen; Sommervoll, Camilla Elise Nergård; Haugen, Christine; Gudbrandsen, Oddrun Anita; Mellgren Christensen, Anne Elisabeth; Rødahl, Eyvind; Fernø, Johan; Dankel, Simon N; Sagen, Jørn V.; Mellgren, Gunnar. 2019. Absence of the proteoglycan decorin reduces glucose tolerance in overfed male mice. Scientific Reports.
  • Ueland, Grethe Åstrøm; Methlie, Paal; Øksnes, Marianne; Thordarson, Hrafnkell B; Sagen, Jørn V.; Kellmann, Ralf; Mellgren, Gunnar; Ræder, Maria B; Dahlqvist, Per; Dahl, Sandra Rinne; Thorsby, Per Medbøe; Løvås, Kristian; Husebye, Eystein Sverre. 2018. The short cosyntropin test revisited: new normal reference range using LC-MS/MS. Journal of Clinical Endocrinology and Metabolism. 1696-1703.
  • Stokke, Silje Agnethe; Myhr, Kjell-Morten; Holmøy, Trygve; Saltyte Benth, Jurate; Wergeland, Stig; Beiske, Antonie Giæver; Bjerve, Kristian S; Hovdal, Harald Olav; Midgard, Rune; Sagen, Jørn V.; Torkildsen, Øivind. 2018. Serum levels of leptin and adiponectin are not associated with disease activity or treatment response in multiple sclerosis. Journal of Neuroimmunology. 73-77.
  • Kareem Eldin, Mohammed Adhmed Abdel Ghafar; Frøysa, Håvard G; Karlsen, Odd Andre; Sagen, Jørn V.; Mellgren, Gunnar; Verhaegen, Steven; Ropstad, Erik; Goksøyr, Anders; Kellmann, Ralf. 2018. LC-MS/MS based profiling and dynamic modelling of the steroidogenesis pathway in adrenocarcinoma H295R cells. Toxicology in Vitro. 332-341.
  • Bjune, Jan-Inge; Haugen, Christine; Gudbrandsen, Oddrun Anita; Nordbø, Ole Petter; Nielsen, Hans Jørgen; Våge, Villy; Njølstad, Pål Rasmus; Sagen, Jørn V.; Dankel, Simon N; Mellgren, Gunnar. 2018. IRX5 regulates adipocyte amyloid precursor protein and mitochondrial respiration in obesity. International Journal of Obesity.
  • Ueland, Grethe Åstrøm; Methlie, Paal; Jøssang, Dag Eirik; Sagen, Jørn V.; Viste, Kristin; Thordarson, Hrafnkell B; Heie, Anette; Grytaas, Marianne; Løvås, Kristian; Biermann, Martin; Husebye, Eystein Sverre. 2018. Adrenal Venous Sampling for Assessment of Autonomous Cortisol Secretion. Journal of Clinical Endocrinology and Metabolism. 4553-4560.
  • Bozickovic, Olivera; Skartveit, Linn; Svendsen, Agnete; Helland, Thomas; Jonsdottir, Kristin; Flågeng, Marianne Hauglid; Fenne, Ingvild Sveinsgjerd; Janssen, Emiel; Lorens, James; Bjørkhaug, Lise; Sagen, Jørn V.; Mellgren, Gunnar. 2018. A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells. Journal of Steroid Biochemistry and Molecular Biology. 57-70.
  • Veum, Vivian Lohmann; Laupsa-Borge, Johnny; Eng, Øyvin Andre Solberg; Rostrup, Espen; Larsen, Terje H; Nordrehaug, Jan Erik; Nygård, Ottar; Sagen, Jørn V.; Gudbrandsen, Oddrun Anita; Dankel, Simon N; Mellgren, Gunnar. 2017. Visceral adiposity and metabolic syndrome after very high-fat and low-fat isocaloric diets: A randomized controlled trial. American Journal of Clinical Nutrition. 85-99.
  • Sagen, Jørn V.; Bjørkhaug, Lise; Haukanes, Bjørn Ivar; Grevle, Louise; Molnes, Janne; Nedrebø, Bjørn Gunnar; Søvik, Oddmund; Njølstad, Pål Rasmus; Johansson, Stefan; Molven, Anders. 2017. The HNF1A mutant Ala180Val: Clinical challenges in determining causality of a rare HNF1A variant in familial diabetes. Diabetes Research and Clinical Practice. 142-149.
  • Grytaas, Marianne Aardal; Strømsøy, Siri S.; Rørvik, Jarle; Arnes, Jarle; Heie, Anette; Arnesen, Thomas; Jørstad, Melissa Davidsen; Nedrebø, Bjørn Gunnar; Jøssang, Dag Eirik; Jensen, Dag Kjartan; Rørvik, Håvard D.; Sagen, Jørn V.; Mellgren, Gunnar; Thordarson, Hrafnkell B; Husebye, Eystein Sverre; Løvås, Kristian. 2017. Clinical Characteristics and Long-Term Outcome of Primary Aldosteronism in a Norwegian Population. Hormone and Metabolic Research. 838-846.
  • Madsen, Andre Greger; Bjune, Jan Inge; Bjørkhaug, Lise; Mellgren, Gunnar; Sagen, Jørn V. 2016. The cAMP-dependent protein kinase downregulates glucose-6-phosphatase expression through RORα and SRC-2 coactivator transcriptional activity. Molecular and Cellular Endocrinology. 92-101.
  • Stokke, Silje Agnethe; Methlie, Paal; Løvås, Kristian; Sagen, Jørn V. 2016. Nedsatt følsomhet for thyreoideahormon. Tidsskrift for Den norske legeforening. 618-622.
  • Avila, Magali; Dyment, David A.; Sagen, Jørn V.; St-Onge, Judith; Moog, Ute; Chung, Brian Hon-Yin; Mo, S.; Mansour, Sahar; Albanese, Assunta; Garcia, Sixto; Martin, David Ortiz; Lopez, Ainhoa Abad; Claudi, Tor; König, Rainer; White, Susan M.; Sawyer, Sarah L.; Bernstein, Jon A.; Slattery, Leah; Jobling, Rebekah K.; Yoon, Grace; Curry, Cynthia J.; Le Merrer, Martine; Le Luyer, Bernard; Héron, Delphine; Mathieu-Dramard, Michèle; Bitoun, Pierre; Odent, Sylvie; Amiel, Jeanne; Kuentz, Paul; Thevenon, Julien; Laville, Martine; Reznik, Yves; Fagour, Cédric; Nunes, Marie-Laure; Delesalle, Dorothée; Manouvrier, Sylvie Hanu; Lascols, Olivier; Huet, Frédéric; Binquet, Christine; Faivre, Laurence; Rivière, Jean-Baptiste; Vigouroux, Corinne; Njølstad, Pål Rasmus; Innes, Allan Micheil; Thauvin-Robinet, Christel. 2016. Clinical reappraisal of SHORT syndrome with PIK3R1 mutations: Toward recommendation for molecular testing and management. Clinical Genetics. 501-506.
  • Madsen, Andre Greger; Bozickovic, Olivera; Bjune, Jan Inge; Mellgren, Gunnar; Sagen, Jørn V. 2015. Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2). Scientific Reports.
  • Bozickovic, Olivera; Hoang, Tuyen; Fenne, Ingvild Sveinsgjerd; Helland, Thomas; Skartveit, Linn; Ouchida, Mamoru; Mellgren, Gunnar; Sagen, Jørn V. 2015. Cyclin C interacts with steroid receptor coactivator 2 and upregulates cell cycle genes in MCF-7 cells. BBA - Molecular Cell Research. 2383-2391.
  • Stokke, Silje Agnethe; Myhr, Kjell-Morten; Holmøy, Trygve; Saltyte Benth, Jurate; Wergeland, Stig; Beiske, Antonie Giæver; Bjerve, Kristian S; Hovdal, Harald Olav; Lilleås, Finn; Midgard, Rune; Pedersen, Tom; Bakke, Søren Jacob; Michelsen, Annika; Aukrust, Pål; Ueland, Thor; Sagen, Jørn V.; Torkildsen, Øivind. 2015. Body mass index influence interferon-beta treatment response in multiple sclerosis. Journal of Neuroimmunology. 92-97.
  • Dankel, Simon E Nitter; Degerud, Eirik Magnus Meek; Borkowski, Kamil; Fjære, Even; Midtbø, Lisa Kolden; Haugen, Christine; Solsvik, Margit; Lavigne, Ann Marie; Liaset, Bjørn; Sagen, Jørn V.; Kristiansen, Karsten; Mellgren, Gunnar; Madsen, Lise. 2014. Weight cycling promotes fat gain and altered clock gene expression in adipose tissue in C57BL/6J mice. American Journal of Physiology. Endocrinology and Metabolism. E210-E224.
  • Negahdar, Maria; Aukrust, Ingvild; Molnes, Janne; Solheim, Marie Holm; Johansson, Bente Berg; Sagen, Jørn V.; Dahl-Jørgensen, Knut; Kulkarni, Rohit Rajesh; Søvik, Oddmund; Flatmark, Torgeir; Njølstad, Pål Rasmus; Bjørkhaug, Lise. 2014. GCK-MODY diabetes as a protein misfolding disease: The mutation R275C promotes protein misfolding, self-association and cellular degradation. Molecular and Cellular Endocrinology. 55-65.
  • Dankel, Simon E Nitter; Svärd, Jessica; Matthä, Simone; Claussnitzer, Melina; Klöting, Nora; Glunk, Viktoria; Fandalyuk, Zinayida; Grytten, Elise; Solsvik, Margit; Nielsen, Hans Jørgen; Busch, Christian; Hauner, Hans; Blüher, Matthias; Skurk, Thomas; Sagen, Jørn V.; Mellgren, Gunnar. 2014. COL6A3 expression in adipocytes associates with insulin resistance and depends on PPARγ and adipocyte size. Obesity. 1807-1813.
  • Hoang, Tuyen; Fenne, Ingvild Sveinsgjerd; Madsen, Andre Greger; Bozickovic, Olivera; Johannessen, Mona; Bergsvåg, Mari; Lien, Ernst Asbjørn; Stallcup, Michael R.; Sagen, Jørn V.; Moens, Ugo; Mellgren, Gunnar. 2013. cAMP response element-binding protein interacts with and stimulates the proteasomal degradation of the nuclear receptor coactivator GRIP1. Endocrinology. 1513-1527.
  • Chudasama, Kishan Kumar; Winnay, Jonathan; Johansson, Stefan; Claudi, Tor; König, Rainer; Haldorsen, Ingfrid S.; Johansson, Bente Berg; Woo, Ju Rang; Aarskog, Dagfinn; Sagen, Jørn V.; Kahn, C. Ronald; Molven, Anders; Njølstad, Pål Rasmus. 2013. SHORT syndrome with partial lipodystrophy due to impaired phosphatidylinositol 3 kinase signaling. American Journal of Human Genetics. 150-157.
  • York, Brian; Sagen, Jørn V.; Tsimelzon, Anna; Louet, Jean Francois; Chopra, Atul R.; Reineke, Erin L.; Zhou, Suoling; Stevens, Robert D.; Wenner, Brett R.; Ilkayeva, Olga; Bain, James R.; Xu, Jianming; Hilsenbeck, Susan G.; Newgard, Christopher B.; O'Malley, Bert W. 2013. Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family. Molecular Endocrinology. 366-380.
  • Søvik, Oddmund; Irgens, Henrik Underthun; Molnes, Janne; Sagen, Jørn V.; Bjørkhaug, Lise; Ræder, Helge; Molven, Anders; Njølstad, Pål Rasmus. 2013. Monogenetic diabetes mellitus in Norway :. Norsk Epidemiologi. 55-60.
  • Fenne, Ingvild Sveinsgjerd; Helland, Thomas; Flågeng, Marianne Hauglid; Dankel, Simon E Nitter; Mellgren, Gunnar; Sagen, Jørn V. 2013. Downregulation of steroid receptor coactivator-2 modulates estrogen-responsive genes and stimulates proliferation of MCF-7 breast cancer cells. PLOS ONE. 10 pages.
  • Veum, Vivian Lohmann; Dankel, Simon E Nitter; Gjerde, Jennifer; Nielsen, Hans Jørgen; Solsvik, Margit Hildershavn; Haugen, Christine; Christensen, Bjørn Jostein; Hoang, Tuyen; Fadnes, Dag Jone Stokke; Busch, Christian; Våge, Villy; Sagen, Jørn V.; Mellgren, Gunnar. 2012. The nuclear receptors NUR77, NURR1 and NOR1 in obesity and during fat loss. International Journal of Obesity. 1195-1202.
  • York, Brian; Reineke, Erin L.; Sagen, Jørn V.; Nikolai, Bryan C.; Zhou, Suoling; Louet, Jean Francois; Chopra, Atul R.; Chen, Xian; Reed, Graham; Noebels, Jeffrey; Adesina, Adekunle M.; Yu, Hui; Wong, Lee-Jun C.; Tsimelzon, Anna; Hilsenbeck, Susan; Stevens, Robert D.; Wenner, Brett R.; Ilkayeva, Olga; Xu, Jianming; Newgard, Christopher B.; O'Malley, Bert W. 2012. Ablation of Steroid Receptor Coactivator-3 Resembles the Human CACT Metabolic Myopathy. Cell Metabolism. 752-763.
  • Dankel, Simon E Nitter; Hoang, Tuyen; Flågeng, Marianne Hauglid; Sagen, Jørn V.; Mellgren, Gunnar. 2010. cAMP-mediated regulation of HNF-4 alpha depends on the level of coactivator PGC-1 alpha. BBA - Molecular Cell Research. 1013-1019.
  • Dankel, Simon E Nitter; Fadnes, Dag Jone Stokke; Stavrum, Anne-Kristin; Stansberg, Christine; Holdhus, Rita; Hoang, Tuyen; Veum, Vivian Lohmann; Christensen, Bjørn Jostein; Våge, Villy; Sagen, Jørn V.; Steen, Vidar Martin; Mellgren, Gunnar. 2010. Switch from stress response to homeobox transcription factors in adipose tissue after profound fat loss. PLOS ONE. 12 pages.
  • York, Brian; Yu, Chundong; Sagen, Jørn V.; Liu, Zhaoliang; Nikolai, Bryan C.; Wu, Ray-Chang; Finegold, Milton; Xu, Juanming; O'Malley, Bert W. 2010. Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology. Proceedings of the National Academy of Sciences of the United States of America. 11122-11127.
  • Fenne, Ingvild Sveinsgjerd; Hoang, Tuyen; Hauglid, Marianne; Sagen, Jørn V.; Lien, Ernst Asbjørn; Mellgren, Gunnar. 2008. Recruitment of coactivator glucocorticoid receptor interacting protein 1 to an estrogen receptor transcription complex is regulated by the 3',5'-cyclic adenosine 5'-monophosphate-dependent protein kinase. Endocrinology. 4336-4345.
  • Sagen, Jørn V.; Bjørkhaug, Lise; Molnes, Janne; Ræder, Helge; Grevle, Louise; Søvik, Oddmund; Molven, Anders; Njølstad, Pål Rasmus. 2008. Diagnostic screening of MODY2/GCK mutations in the Norwegian MODY Registry. Pediatric Diabetes. 442-449.
  • Søvik, Oddmund; Tansek, Mojca Zerjav; Sagen, Jørn V.; Njølstad, Pål Rasmus. 2007. Management of neonatal and infancy-onset diabetes mellitus. Endocrine Development. 94-105.
  • Ræder, Helge; Johansson, Stefan; Holm, Pål I.; Haldorsen, Ingfrid S.; Mas, Eric; Sbarra, Véronique; Nermoen, Ingrid; Eide, Stig Åge; Grevle, Louise; Bjørkhaug, Lise; Sagen, Jørn V.; Aksnes, Lage; Søvik, Oddmund; Lombardo, Dominique; Molven, Anders; Njølstad, Pål Rasmus. 2006. Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction. Nature Genetics. 54-62.
  • Sagen, JV; Odili, S; Bjørkhaug, L.; Zelent, D; Buettger, C; Kwagh, J; Stanley, C; Dahl-Jørgensen, Knut; de Beaufort, CE; Bell, GI; Han, Y; Grimsby, J; Taub, R; Molven, A; Søvik, Oddmund; Njølstad, PR; Matschinsky, FM. 2006. From clinicogenetic studies of maturity-onset diabetes of the young to unraveling complex mechanisms of glucokinase regulation. Diabetes. 1713-1722.
  • Ræder, Helge; Bjørkhaug, Lise; Johansson, Stefan; Mangseth, Kjersti; Sagen, Jørn V.; Hunting, Anne; Følling, Ivar; Johansen, Odd; Bjørgaas, Marit; Paus, Povel N.; Søvik, Oddmund; Molven, Anders; Njølstad, Pål Rasmus. 2006. A hepatocyte nuclear factor-4 alpha gene (HNF4A) P2 promoter haplotype linked with late-onset diabetes - Studies of HNF4A variants in the Norwegian MODY registry. Diabetes. 1899-1903.
  • Sagen, Jørn V.; Pearson, Ewan R.; Johansen, Anders; Spyer, Ghislaine; Søvik, Oddmund; Pedersen, Oluf; Njølstad, Pål Rasmus; Hattersley, Andrew T.; Hansen, Torben. 2005. Preserved insulin response to tolbutamide in hepatocyte nuclear factor-1 alpha mutation carriers. Diabetic Medicine. 406-409.
  • Gundersen, Lise Bj.; Johansson, Stefan; Ræder, Helge; Undlien, Dag E.; Molven, Anders; Søvik, Oddmund; Thorsby, Per; Sagen, Jørn V.; Njølstad, Pål Rasmus. 2005. Molekylærgenetisk diagnostikk ved diabetes mellitus. Tidsskrift for Den norske legeforening. 2968-2972.
  • Sagen, Jørn V.; Baumann, Maren E.; Salvesen, Helga; Molven, Anders; Søvik, Oddmund; Njølstad, Pål Rasmus. 2005. Diagnostic screening of NEUROD1 (MODY6) in subjects with MODY or gestational diabetes mellitus. Diabetic Medicine. 1012-1015.
  • Sagen, Jørn V.; Ræder, Helge; Hathout, Eba; Gudmundsson, K; Bævre, H; Abuelo, D; Phornphutkul, C; Molnes, Janne; Bell, GI; Gloyn, AL; Hattersley, AT; Molven, Anders; Søvik, Oddmund; Njølstad, Pål Rasmus. 2004. Permanent neonatal diabetes due to mutations in KCNJ11 encoding Kir6.2 - Patient characteristics and initial response to sulfonylurea therapy. Diabetes. 2713-2718.
  • Akbari, M; Skjelbred, C; Folling, I; Sagen, Jørn V.; Krokan, HE. 2004. A gel electrophoresis method for detection of mitochondrial DNA mutation (3243 tRNA (Leu (UUR))) applied to a Norwegian family with diabetes mellitus and hearing loss. Scandinavian Journal of Clinical and Laboratory Investigation. 86-92.
  • Njølstad, Pål Rasmus; Sagen, Jørn V.; Bjørkhaug, Lise; Odili, Stella; Shehadeh, Naim; Bakry, Doua; Sarici, U; Alpay, Faruk; Molnes, Janne; Molven, Anders; Søvik, Oddmund; Matschinsky, Franz M. 2003. Permanent neonatal diabetes caused by glucokinase deficiency; inborn error of the glucose-insulin signaling pathway. Diabetes. 2854-2860.
  • Gundersen, Lise Bj.; Sagen, Jørn V.; Thorsby, P; Søvik, Oddmund; Molven, Anders; Njølstad, Pål Rasmus. 2003. Hepatocyte nuclear factor-1 alpha gene mutations and diabetes in Norway. Journal of Clinical Endocrinology and Metabolism. 920-931.
  • Bjørkhaug, L; Sagen, Jørn V.; Thorsby, P; Søvik, Oddmund; Molven, Anders; Njølstad, Pål Rasmus. 2003. Hepatocyte nuclear factor- 1 alpha gene mutations and diabetes in Norway. Journal of Clinical Endocrinology and Metabolism. 920-931.
  • Sagen, Jørn V.; Bostad, Leif; Njølstad, Pål Rasmus; Søvik, Oddmund. 2003. Enlarged nephrons and severe non-diabetic nephropathy in hepatocyte nuclear factor (HNF)-1 beta mutation carriers. Kidney International. 793-800.
  • Sagen, Jørn V.; Bostad, Leif; Njølstad, Pål Rasmus; Søvik, Oddmund. 2003. Enlarged nephrons and severe non-diabetic nephropathy in hepatocyte nuclear factor (HNF)-1 beta mutation carriers. Kidney International. 793-800.
  • Sagen, Jørn V.; Njølstad, Pål Rasmus; Søvik, Oddmund. 2002. Reduced prevalence of late-diabetic complications in MODY3 with early diagnosis. Diabetic Medicine. 697-703.
  • Njølstad, Pål Rasmus; Søvik, Oddmund; Cockburn, B. N.; Bell, G. I.; Følling, I.; Sagen, Jørn V. 1998. Ikke-insulinkrevende diabetes mellitus hos barn og unge voksne. Tidsskrift for Den norske legeforening. 1054-1057.
Lecture
  • Dankel, Simon N; Tallapragada, Divya Sri Priyanka; Armstrong, Nasa-Sinnott; Sagen, Jørn V.; Claussnitzer, Melina; Mellgren, Gunnar. 2019. Integrative Genomics Links Homeobox Transcription Factors to Risk of Visceral Adiposity .
Academic lecture
  • Nilsen, Mona Synnøve; Åsen Jersin, Regine; McCann, Adrian; Ulvik, Arve; Madsen, Andre; Svensson, Per-Arne; Sagen, Jørn V.; Ueland, Per Magne; Tell, Grethe S.; Mellgren, Gunnar; Dankel, Simon N. 2019. Circulating 3-hydroxyisobutyrate (3-HIB) as a clinical marker of prediabetes and T2D in patients with obesity.
  • Nilsen, Mona Synnøve; Åsen Jersin, Regine; Madsen, Andre; McCann, Adrian; Svensson, Per-Arne; Ueland, Per Magne; Sagen, Jørn V.; Mellgren, Gunnar; Dankel, Simon N. 2018. Amino acid metabolism in adipocytes.
  • Dankel, Simon E Nitter; Degerud, Eirik Magnus Meek; Fjære, Even; Haugen, Christine; Sagen, Jørn V.; Mellgren, Gunnar; Madsen, Lise. 2012. Weight cycling affects adipose tissue genes involved in circadian rhythm and lipid metabolism.
  • Dankel, Simon E Nitter; Fadnes, Dag Jone Stokke; Christoforou, Andrea; Haugen, Christine; Røst, Therese Halvorsen; Gudbrandsen, Oddrun Anita; Veum, Vivian Lohmann; Solsvik, Margit; Våge, Villy; Nielsen, Hans Jørgen; Busch, Christian; Sagen, Jørn V.; Steen, Vidar Martin; Mellgren, Gunnar. 2012. Integrative genomics links homeobox transcription factors to intra-abdominal obesity.
  • Sagen, Jørn V. 2007. Overvekt og Diabetes.
  • Sagen, Jørn V. 2007. Nyheter innen MODY-forskningen.
  • Sagen, Jørn V. 2007. Management of Neonatal and Infancy-onset Diabetes.
  • Sagen, Jørn V. 2004. Bevart sulfonylurea-indusert insulinsekresjon ved MODY3.
  • Sagen, Jørn V. 2004. Baseline and glucose entrained insulin oscillations in MODY3.
  • Sagen, Jørn V.; Njølstad, Pål Rasmus; Cockburn, B. N.; Bell, G. I. 1998. Mody 3 i en norsk familie.
  • Sagen, Jørn V.; Njølstad, Pål Rasmus; Cockburn, B. N.; Bell, G. I.; Følling, I.; Søvik, Oddmund. 1998. MODY3 in a Norwegian family with severe diabetic eye complications.
Masters thesis
  • Dankel, Simon. 2006. Role of cAMP/PKA in Regulation of GRIP1- and PGC1alpha-Mediated Coactivation of Nuclear Receptor HNF4Alpha.
Popular scientific article
  • Njølstad, Pål Rasmus; Sagen, Jørn V. 2003. Klinisk molekylærmedisin (4): Koblingsanalyser. Pediatrisk Endokrinologi. 34-38.
Feature article
  • Søvik, Oddmund; Njølstad, Pål Rasmus; Følling, I.; Sagen, Jørn V.; Cockburn, B. N.; Bell, G. I. 1998. Hyperexacitability to sulphonylurea in MODY3. Diabetologia. 607-608.
Doctoral dissertation
  • Madsen, Andre Greger. 2015. Function and regulation of Steroid Receptor Coactivator 2. Transcriptional regulation of cellular metabolism.
  • Sagen, Jørn V. 2005. Clinical and molecular aspects of monogenic diabetes mellitus.
Academic chapter/article/Conference paper
  • Sagen, Jørn V. 2011. Sykdomslære. 55 pages.
  • Moi, Line Leonore Haugan; Flågeng, Marianne Hauglid; Dankel, Simon E Nitter; Hoang, Tuyen; Gjerde, Jennifer; Sagen, Jørn V.; Lien, Ernst Asbjørn; Mellgren, Gunnar. 2011. Steroid Receptor Coactivators and Endocrine Treatment in Breast Cancer. 32 pages.
  • Sagen, Jørn V. 2011. Fysisk aktivitet. 11 pages.
  • Søvik, Oddmund; Sagen, Jørn V.; Njølstad, Pål Rasmus. 2008. MODY5 due to mutations in TCF2 (HNF-1ß): The clinical spectrum with special reference to urogenital malformations. 7 pages.
Abstract
  • Hoang, Tuyen; Dankel, Simon E Nitter; Fadnes, Dag Jone Stokke; Veum, Vivian Lohmann; Våge, Villy; Steen, Vidar Martin; Sagen, Jørn V.; Mellgren, Gunnar. 2010. Gene Expression Profile of Nuclear Receptors and Coregulators in Adipose Tissues in Morbid Obesity and after Profound Fat Loss. Endocrine reviews. 1 pages.
  • Dankel, Simon E Nitter; Fadnes, Dag Jone Stokke; Stavrum, Anne-Kristin; Stansberg, Christine; Holdhus, Rita; Hoang, Tuyen; Veum, Vivian Lohmann; Christensen, Bjørn Jostein; Våge, Villy; Sagen, Jørn V.; Steen, Vidar Martin; Mellgren, Gunnar. 2010. From stress response to developmental processes in abdominal subcutaneous adipose tissue after bariatric surgery. Endocrine journal. S429-S429.
Poster
  • Nilsen, Mona Synnøve; Åsen Jersin, Regine; Madsen, Andre; McCann, Adrian; Svensson, Per-Arne; Ueland, Per Magne; Sagen, Jørn V.; Mellgren, Gunnar; Dankel, Simon N. 2019. Adipocyte amino acid metabolism in obesity-related metabolic diseases .
  • Bjune, Jan-Inge; Haugen, Christine; Gudbrandsen, Oddrun Anita; Nordbø, Ole Petter; Njølstad, Pål Rasmus; Sagen, Jørn V.; Dankel, Simon N; Mellgren, Gunnar. 2018. Irx5 regulates body weight via amyloid precursor protein (App) and mitochondrial respiration in adipocytes.
  • Bjune, Jan-Inge; Haugen, Christine; Gudbrandsen, Oddrun Anita; Nordbø, Ole Petter; Njølstad, Pål Rasmus; Sagen, Jørn V.; Dankel, Simon N; Mellgren, Gunnar. 2018. Irx5 regulates body weight via amyloid precursor protein and mitochondrial respiration in adipocytes.
  • Jersin, Regine; Madsen, Andre; Willems, Aron; Sagen, Jørn V.; Mellgren, Gunnar; Dankel, Simon N. 2018. Impaired D-serine uptake in adipocytes promotes oxidative stress and visceral obesity.
  • Madsen, Andre; Bozickovic, Olivera; Bjune, Jan-Inge; Mellgren, Gunnar; Sagen, Jørn V. 2016. Repression of liver SRC-2 by metformin inhibits glucose, lipid and cholesterol biosynthesis.
  • Bjune, Jan-Inge; Madsen, Andre; Bjørkhaug, Lise; Mellgren, Gunnar; Sagen, Jørn V. 2016. PKA downregulates glucose-6phosphatase Expression through RORα and SRC2.
  • Flågeng, Marianne Hauglid; Bozickovic, Olivera; Skartveit, Linn; Sagen, Jørn V.; Mellgren, Gunnar. 2014. Steroid receptor coactivators during short-term estrogen deprivation.
  • Haugen, Christine; Dankel, Simon N; Kim, K. Han; Solsvik, Margit; Sagen, Jørn V.; Gudbrandsen, Oddrun Anita; Hui, C.-C.; Mellgren, Gunnar. 2014. Role of homeobox transcription factors IRX3 and IRX5 in mitochondrial development and activity in adipose tissue.
  • Veum, Vivian Lohmann; Laupsa-Borge, Johnny; Eng, Øyvin Solberg; Rostrup, Espen; Larsen, Terje H; Nordrehaug, Jan Erik; Nygård, Ottar; Sagen, Jørn V.; Dankel, Simon E Nitter; Mellgren, Gunnar. 2014. A moderate energy-restricted very-high-fat diet reduces fat mass and improves metabolic health in abdominally obese middle-aged men.
  • Haugen, Christine; Dankel, Simon E Nitter; Kim, K. Han; Solsvik, Margit; Sagen, Jørn V.; Gudbrandsen, Oddrun Anita; Hui, C.-C.; Mellgren, Gunnar. 2013. Role of homeobox transcription factor IRX5 in obesity and metabolic health.
  • Haugen, Christine; Dankel, Simon E Nitter; Kim, K. Han; Solsvik, Margit; Sagen, Jørn V.; Gudbrandsen, Oddrun Anita; Hui, C.-C.; Mellgren, Gunnar. 2013. Deficiency of Irx5 is associated with decreased fat mass in male CD1 mice.
  • Dankel, Simon E Nitter; Degerud, Eirik Magnus Meek; Fjære, Even; Haugen, Christine; Sagen, Jørn V.; Mellgren, Gunnar; Madsen, Lise. 2012. Candidate genes for fat regain after weight cycling in mice.
  • Degerud, Eirik Magnus Meek; Dankel, Simon E Nitter; Fjære, Even; Haugen, Christine; Sagen, Jørn V.; Mellgren, Gunnar; Madsen, Lise. 2012. CDKN1A associates with fat regain after weight cycling in mice.
  • Veum, Vivian Lohmann; Dankel, Simon E Nitter; Gjerde, Jennifer; Nielsen, Hans Jørgen; Solsvik, Margit Hildershavn; Haugen, Christine; Christensen, Bjørn Jostein; Hoang, Tuyen; Busch, Christian; Fadnes, Dag Jone Stokke; Våge, Villy; Sagen, Jørn V.; Mellgren, Gunnar. 2011. The nuclear receptors NURR77, NURR1 and NOR1 in obesity and during fat loss.
  • Dankel, Simon E Nitter; Fadnes, Dag Jone Stokke; Gudbrandsen, Oddrun Anita; Veum, Vivian Lohmann; Våge, Villy; Steen, Vidar Martin; Sagen, Jørn V.; Mellgren, Gunnar. 2011. Prediction of obesity candidate genes by multiple gene expression analyses of adipose tissue.
  • Dankel, Simon E Nitter; Fadnes, Dag Jone Stokke; Gudbrandsen, Oddrun Anita; Veum, Vivian Lohmann; Våge, Villy; Steen, Vidar Martin; Sagen, Jørn V.; Mellgren, Gunnar. 2010. Low Omental Expression of Fat Loss-Associated Homeobox Transcription Factors in Morbid Obesity.
  • Hoang, Tuyen; Dankel, Simon E Nitter; Fadnes, Dag Jone Stokke; Veum, Vivian Lohmann; Våge, Villy; Steen, Vidar M; Sagen, Jørn V.; Mellgren, Gunnar. 2010. Gene Expression Profile of Nuclear Receptors and Coregulators in Adipose Tissues in Morbid Obesity and after Profound Fat Loss.
  • Dankel, Simon E Nitter; Fadnes, Dag Jone Stokke; Stavrum, Anne-Kristin; Stansberg, Christine; Holdhus, Rita; Hoang, Tuyen; Veum, Vivian Lohmann; Christensen, Bjørn Jostein; Våge, Villy; Sagen, Jørn V.; Steen, Vidar Martin; Mellgren, Gunnar. 2010. From stress response to developmental processes in abdominal subcutaneous adipose tissue after bariatric surgery.
  • Dankel, Simon E Nitter; Hoang, Tuyen; Sagen, Jørn V.; Mellgren, Gunnar. 2008. cAMP/PKA Exerts Differential Effects on GRIP1- and PGC-1α-Mediated HNF-4α Transcriptional Activity in HepG2 and COS-1 Cells.
  • Dankel, Simon E Nitter; Hoang, Tuyen; Sagen, Jørn V.; Mellgren, Gunnar. 2008. cAMP Regulates Nuclear Receptor Coactivator GRIP1–Mediated Coactivation of HNF-4alpha in HepG2 Cells.
  • Mellgren, Gunnar; Hoang, Tuyen; Sagen, Jørn V.; Dankel, Simon E Nitter. 2007. Regulation of HNF-4alpha transcriptional activity by the coactivators GRIP1 and PGC-1alpha.
Academic literature review
  • Sagen, Jørn V. 2011. Nuclear hormone receptors – a family of hormone dependent transcriptional regulators. 30-35.

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