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Jutta Dierkes

Professor, Clinical Nutrition
  • E-mailJutta.Dierkes@uib.no
  • Phone+47 55 97 73 44
  • Visitor Address
    Center for Nutrition, Childrens' hospital, block 1, 5th floor
    5021 Bergen
  • Postal Address
    Postboks 7804
    5020 Bergen

I am the head of the 'Mohn Nutrition Research Laboratory', funded by the Trond Mohn foundation (https://mohnfoundation.no/nutrition-research/?lang=en). This is a large collaboration between nutritionists, dietitians, medical doctors, and molecular biologists with the aim to study the nutritional challenges of obesity and undernutrition - from the molecular level to clinical and epidemiologic approaches. Nutritional assessment of the participants in the Hordaland Health Studies 3 (HUSK3) is part of the Mohn laboratory. More information aobut HUSK3 can be found here: www.husk.w.uib.no/husk3/

Collaboration with the HUSK consortium is well established, and we investigated specifically the association of seafood intake and different health outcomes, including the metabolic syndrome, bone mineral density and hip fractures. These investigations will be continued by using data from HUSK3.

Fish is a major dietary source of vitamin D, and I have been interested in the health effects of vitamin D both in healthy populations and in patients with cardiovascular disease, and in vitamin D from fish and supplements. Fish is also a rich source of protein, and protein intake is, for example an issue in old adults and in patients with chronic kidney disease. Here, we also have ongoing projects studying the associations of dietary intake in hospitalized patients and patients with CKD with different health outcomes.

Seafood consumption is threatened by pollution, and I am especially interested in the pollution with micro- and nanoplastics. Together with colleagues from environmental toxicology and the Institute of Marine Research, we have received funding from the University of Bergen within the priority area of marine research (https://www.uib.no/en/marine) to study the health effects of microplastics. Recently, I was invited as a member of the new "North Atlantic Microplastic Centre" and I am happy to join!

In 2019, we received funding from the Joint programming initiative "A healthy diet for a healthy life" with the CarbHealth project, were we will study, together with colleagues from Sweden and Germany, the health effects of carbohydrates.

Courses

Bachelorprogram in Human Nutrition

NUTR100   Introduction to clinical nutrition

Nutr203     Nutrition physiology

NUTR245    Lifestyle and Lifecycle

NUTR295    Bachelor thesis

 

Masterprogram in Human Nutrition

NUTR333A    Human Nutrition

 

Masterprogram in Clinical Nutrition

NUCLI362   Genetic disorders in Nutrient Metabolism

VALGTVEPS Felles praksisemne i aldersmedisin (norgewian only)

 

Academic article
  • 2019. Short-term treatment with a peroxisome proliferator-activated receptor α agonist influences plasma one-carbon metabolites and B-vitamin status in rats. PLOS ONE. 1-13.
  • 2019. Dietary choline is related to increased risk of acute myocardial infarction in patients with stable angina pectoris. Biochimie.
  • 2018. Total and lean fish intake is positively associated with bone mineral density in older women in the community-based Hordaland Health Study. European Journal of Nutrition. 1-11.
  • 2018. Plasma 25-hydroxyvitamin D and mortality in patients with suspected stable angina pectoris. Journal of Clinical Endocrinology and Metabolism. 1161-1170.
  • 2018. Limited benefit of fish consumption on risk of hip fracture among men in the community-based Hordaland health study. Nutrients. 13 pages.
  • 2018. High rates of central obesity and sarcopenia in CKD irrespective of renal replacement therapy - An observational cross-sectional study. BMC Nephrology. 1-9.
  • 2018. Adherence to the Healthy Nordic Food Index and the incidence of acute myocardial infarction and mortality among patients with stable angina pectoris. Journal of human nutrition and dietetics. 86-97.
  • 2017. Vitamin D supplementation and its influence on muscle strength and mobility in community-dwelling older persons: a systematic review and meta-analysis. Journal of human nutrition and dietetics. 3-15.
  • 2017. Serum acylcarnitines and risk of cardiovascular death and acute myocardial infarction in patients with stable angina pectoris. Journal of the American Heart Association. 1-28.
  • 2017. Associations between intake of fish and n-3 long-chain polyunsaturated fatty acids and plasma metabolites related to the kynurenine pathway in patients with coronary artery disease. European Journal of Nutrition. 261-272.
  • 2017. Associations between fish intake and the metabolic syndrome and its components among middle-aged men and women: the Hordaland Health Study. Food & Nutrition Research. 11 pages.
  • 2016. Cosinor modelling of seasonal variation in 25-hydroxyvitamin D concentrations in cardiovascular patients in Norway. European Journal of Clinical Nutrition. 517-522.
  • 2016. Association between weight change and mortality in community living older people followed for up to 14 years. The Hordaland Health Study (HUSK). The Journal of Nutrition, Health & Aging. 909-917.
  • 2015. Vitamin D3 supplementation: Response and predictors of vitamin D3 metabolites - A randomized controlled trial. Clinical Nutrition.
  • 2015. Vitamin D3 supplementation does not modify cardiovascular risk profile of adults with inadequate vitamin D status. European Journal of Nutrition. 621-634.
  • 2015. Vitamin D status was not associated with 'one-year' progression of coronary artery disease, assessed by coronary angiography in statin-treated patients. European Journal of Preventive Cardiology (EJPC). 594-602.
  • 2015. The association between nut consumption and the risk of total and ischemic stroke in a German cohort study . European Journal of Clinical Nutrition. 431-435.
  • 2015. Potential predictors of plasma fibroblast growth factor 23 concentrations: Cross-sectional analysis in the epic-Germany study. PLOS ONE.
  • 2015. Plasma fibroblast growth factor 23 and risk of cardiovascular disease: results from the EPIC-Germany case-cohort study. European Journal of Epidemiology (EJE). 131-141.
  • 2015. Efficacy of fish intake on Vitamin D status: A meta-analysis of randomized controlled trials. American Journal of Clinical Nutrition. 837-847.
  • 2015. Dietary intake of saturated fat is not associated with risk of coronary events or mortality in patients with established coronary artery disease. Journal of Nutrition. 299-305.
  • 2014. Vitamin D is not linked to folate status and mRNA expression of intestinal proton-coupled folate transporter. European Journal of Nutrition. 1115-1122.
  • 2014. Plasma fibroblast growth factor 23, parathyroid hormone, 25-hydroxyvitamin D3, and risk of heart failure: A prospective, case-cohort study. Journal of Clinical Endocrinology and Metabolism. 947-955.
  • 2014. Dietary, lifestyle, and genetic determinants of vitamin D status: a cross-sectional analysis from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Germany study . European Journal of Nutrition. 731-741.
  • 2013. Vitamin D: do we get enough? : A discussion between vitamin D experts in order to make a step towards the harmonisation of dietary reference intakes for vitamin D across Europe. Osteoporosis International. 1567-1577.
  • 2013. Validation of the German Diabetes Risk Score within a population-based representative cohort. Diabetic Medicine. 1047-1053.
  • 2013. Plasma 25-hydroxyvitamin D and its genetic determinants in relation to incident type 2 diabetes: a prospective case-cohort study. European Journal of Epidemiology (EJE). 743-752.
  • 2013. Plasma 25-hydroxyvitamin D and its genetic determinants in relation to incident myocardial infarction and stroke in the European Prospective Investigation into cancer and nutrition (EPIC)-Germany study. PLOS ONE. 12 pages.
  • 2013. Bioavailability of vitamin D-2 and D-3 in healthy volunteers, a randomized placebo-controlled trial. Journal of Clinical Endocrinology and Metabolism. 4339-4345.
  • 2012. Reliability of plasma fibroblast growth factor 23 as risk biomarker in epidemiological studies measured over a four-month period. Annals of Clinical Biochemistry. 542-545.
  • 2012. Omega-3 status and the relationship between plasma asymmetric dimethylarginine and risk of myocardial infarction in patients with suspected coronary artery disease. Cardiology Research and Practice. 11 pages.
  • 2011. Comparison of two nutritional interventions in obese families. Ernährungs-Umschau (1977). 122-127.
  • 2010. Plasma gamma-glutamyltransferase, cysteinyl-glycine, and oxidized low-density lipoprotein: a pathway associated with myocardial infarction risk? Arteriosclerosis, Thrombosis and Vascular Biology. 2053-2058.
Report
  • 2014. Comparison of organic and conventional food and food Production. Part III: Human health – an evaluation of human studies, animal models studies and biomarker studies. 2014:22-3. 2014:22-3. .
  • 2013. Vurdering av særnorske forhold for produkter som er godkjent som ny mat i EU. Uttalelse fra faggruppen for ernæring, dietetiske produkter, ny mat og allergi i Vitenskapskomiteen for mattrygghet. 2013:45. 2013:45. .
  • 2013. Risk assessment of histidine, methionine, S-adenosylmethionine and tryptophan. Opinion of the Panel on nutrition, dietetic products, novel food and allergy of the Norwegian Scientific Committee for Food Safety. 2013:10. 2013:10. .
  • 2013. Benefit and risk assessment of breastmilk for infant health in Norway. Opinion of the Steering Committee of the Norwegian Scientific Committee for Food Safety. 2013:44. 2013:44. .
  • 2013. Assessment of vitamin A and D in food supplements. Opinion of the Panel on nutrition, dietetic products, novel food and allergy of the Norwegian Scientific Committee for Food Safety. 2013:01. 2013:01. .
  • 2013. Assessment and updating of the fortification model from 2006. Opinion of the Panel on nutrition, dietetic products, novel food and allergy of the Norwegian Scientific Committee for Food Safety. 2013:02. 2013:02. .
Lecture
  • 2016. Association between weight change and mortality in community living older people followed for up to 14 years: the Hordaland Health Study (HUSK).
Academic lecture
  • 2014. VITAMIN D STATUS AND MORTALITY IN PATIENTS WITH STABLE ANGINA.
Other presentation
  • 2017. Supermat i Botanisk hage.
Masters thesis
  • 2020. A randomized, controlled, crossover trial investigating the effects of bread containing guar galactomannan on glucose response in healthy overweight adults.
Feature article
  • 2019. Folkehelseminister mot egen politikk? . Dagsavisen. 1 pages.
Letter to the editor
  • 2018. Long-term supplementation with folic acid and Vitamin B-12 has no effect on circulating uric acid concentrations in Norwegian patients with coronary artery disease. American Journal of Clinical Nutrition. 130-131.
Doctoral dissertation
  • 2019. Biomarkers of one-carbon metabolism and B-vitamin status. Targeted metabolomics in rats and humans exploring the effects of PPARα- activation and dietary composition.
  • 2018. Salmon and cod fillet consumption and effects on metabolic risk factors. Intervention studies in humans and rats with overweight and obesity.
  • 2018. Dietary predictors of bone mineral density, hip fractures, mobility and muscle strength - in community-dwelling older persons.
  • 2016. Vitamin D status and cardiovascular disease. Observational studies in patients who underwent coronary angiography.
Academic chapter/article/Conference paper
  • 2013. B vitamins and disease. 14 pages.
Abstract
  • 2013. DETERMINANTS OF VITAMIN D STATUS IN PATIENTS WITH STABLE ANGINA. Annals of Nutrition and Metabolism. 241-241.
  • 2013. BIOAVAILABILITY OF VITAMIN D2 AND D3 IN HEALTHY VOLUNTEERS - A RANDOMIZED TRIAL. Annals of Nutrition and Metabolism. 909-909.
  • 2013. 25-HYDROXYVITAMIN D, ITS GENETIC DETERMINANTS AND THE RISK OF CARDIOVASCULAR DISEASES IN THE GERMAN ARM OF THE EPIC-STUDY. Annals of Nutrition and Metabolism. 1128-1129.
  • 2011. Vitamin D status in healthy volunteers during autumn and winter. Annals of Nutrition and Metabolism. 36-36.
  • 2011. Different classification of overweight and obesity in children and adolescents: effect on the frequency of overweight and obesity in Delitzsch, Germany. Annals of Nutrition and Metabolism. 339-339.
Poster
  • 2018. Dietary choline and risk of acute myocardial infarction.
  • 2016. Effects of salmon filet intake on blood pressure regulation.
  • 2015. FISH INTAKE AND VITAMIN D STATUS: META-ANALYSIS OF RCTS.
Errata
  • 2018. Correction to: High rates of central obesity and sarcopenia in CKD irrespective of renal replacement therapy - An observational cross-sectional study. BMC Nephrology.
Academic literature review
  • 2018. Development and challenges to breastfeeding in sub-Saharan Africa. 937-944.
  • 2015. Bioavailability of iron, zinc, folate and vitamin A when fortified in condiments and seasonings. 29-42.
Chapter
  • 2013. Good clinical practice. 401-414. In:
    • 2013. Epidemiology: Principles and Practical Guidelines. Elsevier.

More information in national current research information system (CRIStin)

Selected Publications

2020

Van Parys A, Lysne V, Øyen J, Dierkes J, Nygård OK. No effect of plasma trimethylamine N-Oxide (TMAO) and plasma trimethyllysine (TML) on the association between choline intake and acute myocardial infarction risk in patients with stable angina pectoris. Hum Nutr Metab 2020; 21:

Van Parys A, Lysne V, Svingen GFT, Ueland PM, Dhar I, Øyen J, Dierkes J, Nygård OK. Dietary choline is related to increased risk of acute myocardial infarction in patients with stable angina pectoris. Biochimie. 2020 Jun;173:68-75.

Weikert C, Trefflich I, Menzel J, Obeid R, Longree A, Dierkes J, Meyer K, Herter-Aeberli I, Mai K, Stangl GI, Müller SM, Schwerdtle T, Lampen A, Abraham K: Vitamin and mineral status in a vegan diet. Dtsch Arztebl Int 2020; 117: 575–82.

2019

H. Rosendahl-Riise, T. Karlsson, CA Drevon, EM Apalset, OK Nygård, GS Tell, J. Dierkes. Total and lean fish intake is positively associated with bone mineral density in older women in the community-based Hordaland Health Study. Eur J Nutr. 2019; 58:1403-1413

2018

E. Degerud, O. Nygård, S. de Vogel, R. Hoff, GFT. Svingen, ER. Pedersen, DW. Nilsen, JE.   Nordrehaug, Ø. Midttun, PM. Ueland, J. Dierkes. Plasma 25-hydroxyvitamin D and mortality in patients with suspected stable angina pectoris. J Clin Endocrinol Metab. 2018; 103: 1161-1170

H. Rosendahl-Riise, G. Sulo, T. Karlsson, CA Drevon, J. Dierkes, GS Tell. Limited Benefit of Fish Consumption on Risk of Hip Fracture among Men in the Community-Based Hordaland Health Study. Nutrients. 2018 Jul 6;10(7). pii: E873.

2017

T. Karlsson, E. Strand, J. Dierkes, C.A. Drevon, J. Øyen, Ø. Midttun, P.M. Ueland, O.A. Gudbrandsen, E.R. Pedersen, O. Nygård. Associations between intake of fish and n-3 long-chain polyunsaturated fatty acids and plasma metabolites related to the kynurenine pathway in patients with coronary artery disease. Eur J Nutr. 2017;56:261-272

H. Rosendahl-Riise, U. Spielau, A. H. Ranhoff, O. A. Gudbrandsen, J. Dierkes: Vitamin D supplementation and its influence on muscle strength and mobility in community-dwelling older persons: a systematic review and meta-analysis. J Hum Nutr Diet 2017;30:3-15

T. Karlsson, H. Rosendahl-Riise, J. Dierkes, C.A. Drevon, G.S. Tell, O. Nygård: Associations between fish intake and the metabolic syndrome and its components among middle-aged men and women: the Hordaland Health Study. Food Nutr Res. 2017 Jul 3;61(1):1347479. eCollection 2017.

T.R. Haugsgjerd, J. Dierkes, S.E. Vollset,K.J. Vinknes, O.K. Nygård, R. Seifert, G. Sulo, G.S. Tell. Association between weight change and mortality in community living older people followed for up to 14 years. The Hordaland Health Study (HUSK). J Nutr Health Ageing 2017;21:909-917

2016

E. Degerud, R. Hoff, O. Nygård, E. Strand, DW. Nilsen, E. Nordrehaug, Ø. Midttun, PM. Ueland, S. de Vogel, J. Dierkes. Cosinor modelling of seasonal variation in 25-hydroxyvitamin D concentrations in cardiovascular patients in Norway. Eur J Clin Nutr. 2016 Apr;70(4):517-22

U. Lehmann, A. Riedel, F. Hirche, C. Brandsch, M. Girndt, C. Ulrich, E. Seibert, C. Henning, MA. Glomb, J. Dierkes, GI Stangl. Vitamin D(3) supplementation: Response and predictors of vitamin D(3) metabolites - A randomized controlled trial. Clin Nutr. 2016;35:351-358

2015

U. Lehmann, H.R. Gjessing, F. Hirche, A. Mueller-Belecke, O.A. Gudbrandsen, P.M. Ueland, G. Mellgren, L. Lauritzen, H. Lindqvist, A.L. Hansen, A.T. Erkkilä, G.K. Pot, G.I. Stangl, J. Dierkes. Efficacy of fish intake on vitamin D status: a meta-analysis of randomized controlled trials. Am J Clin Nutr. 2015 Oct;102(4):837-47.

E. Degerud, K.H. Løland, O. Nygård, O. Midttun, P.M. Ueland, R. Seifert, E. Strand, O. Bleie, J. Dierkes. Vitamin D status was not associated with 'one-year' progression of coronary artery  disease, assessed by coronary angiography in statin-treated patients. Eur J Prev Cardiol. 2015;22:431-5

2014

R. di Giuseppe, B. Buijsse, F. Hirche, J. Wirth, M. Arregui, S. Westphal, B. Isermann, H.W. Hense, J. Dierkes, H. Boeing, G.I. Stangl, C. Weikert. Plasma Fibroblast Growth Factor 23, Parathyroid Hormone, 25-Hydroxyvitamin D3 and risk of Heart Failure: a prospective, case-cohort study. J Clin Endocrinol Metab. 2014 Mar;99(3):947-55

2013

U. Lehmann, F. Hirche, G. Stangl, K. Hinz, S. Westphal, J. Dierkes. Bioavailability of vitamin D(2) and D(3) in healthy volunteers, a randomized placebo-controlled trial. J Clin Endocrinol Metab. 2013 Nov;98(11):4339-45.

2012

H. Borgeraas, E. Strand, E. Ringdal Pedersen, J. Dierkes, P.M. Ueland, R. Seifert, E.R. Wilberg, P. Bohov, R.K. Berge, D.W. Nilsen, O. Nygård. Omega-3 Status and the Relationship between Plasma Asymmetric Dimethylarginine and Risk of Myocardial Infarction in Patients with Suspected Coronary Artery Disease. Cardiol Res Pract. 2012:201742

2010

Heinz J, Kropf S, Domröse U, Westphal S, Borucki K, Luley C, Neumann KH, Dierkes J. B vitamins and the risk of total mortality and cardiovascular disease in end-stage renal disease: results of a randomized controlled trial. Circulation. 2010 Mar 30;121(12):1432-8.

2009

Borucki K, Weikert C, Fisher E, Jakubiczka S, Luley C, Westphal S, Dierkes J. Haplotypes in the UGT1A1 gene and their role as genetic determinants of bilirubin concentration in healthy German volunteers. Clin Biochem. 2009 Nov;42(16-17):1635-41.

Heinz J, Kropf S, Luley C, Dierkes J. Homocysteine as a risk factor for cardiovascular disease in patients treated by dialysis: a meta-analysis. Am J
Kidney Dis. 2009 Sep;54(3):478-89.

2008

Weikert C, Westphal S, Berger K, Dierkes J, Möhlig M, Spranger J, Rimm EB,
Willich SN, Boeing H, Pischon T. Plasma resistin levels and risk of myocardial
infarction and ischemic stroke. J Clin Endocrinol Metab. 2008 Jul;93(7):2647-53.

2007

Weikert C, Dierkes J, Hoffmann K, Berger K, Drogan D, Klipstein-Grobusch K, Spranger J, Möhlig M, Luley C, Boeing H. B vitamin plasma levels and the risk of ischemic stroke and transient ischemic attack in a German cohort. Stroke. 2007 Nov;38(11):2912-8

Dierkes J, Weikert C, Klipstein-Grobusch K, Westphal S, Luley C, Möhlig M, Spranger J, Boeing H. Plasma pyridoxal-5-phosphate and future risk of myocardial infarction in the European Prospective Investigation into Cancer and Nutrition Potsdam cohort. Am J Clin Nutr. 2007 Jul;86(1):214-20.

Mohn Nutrition Research Laboratory (funded by Trond Mohn foundation https://mohnfoundation.no/nutrition-research/?lang=en)

Hordaland Health Studies (HUSK3, PI: Prof. Grethe S. Tell and Prof. Eva Gerdts) https://husk.w.uib.no/husk3/

Health effects of seafood

Seafood intake and health in the Hordaland Health Studies

Health effects of Microplastics, funded by UiB priority area Marine Research https://www.uib.no/en/marine

Vitamin D and cardiovascular disease: investigations in the WENBIT cohort (collaboration with Prof. Ottar Nygård)

Undernutrition:

Malnutra: The association between undernutrition, biomarkers of nutritional status, quality of life, disease related functions, and future re-hospitalization and mortality (funded by Helse Bergen)

Nutritional challenges in patients with chronic kidney disease (collaboration with Prof. Hans-Peter Marti)

 

CarbHealth: Health effects of carbohydrates, funded by JPI "A healthy diet for a healthy life", with partners in Norway, Sweden and Germany https://healthydietforhealthylife.eu/index.php/projects/research-area-su...

 

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