- E-mailKari.Fladmark@uib.no
- Phone+47 55 58 45 14
- Visitor AddressThormøhlensgt. 53 A/B
- Postal AddressPostboks 78035020 Bergen
Journal articles
- 2019. Dysregulation in the Brain Protein Profile of Zebrafish Lacking the Parkinson’s Disease-Related Protein DJ-1. Molecular Neurobiology. 1-17. doi: 10.1007/s12035-019-01667-w
- 2018. Astroglial DJ-1 over-expression up-regulates proteins involved in redox regulation and is neuroprotective in vivo. Redox Biology. 16: 237-247. doi: 10.1016/j.redox.2018.02.010
- 2018. The protein cargo of endothelial cell-derived extracellular vesicles released in response to IL-3 identifies the Wnt signaling pathway as a relevant mediator of inflammation. Journal of Extracellular Vesicles. doi: 10.1080/20013078.2018.1461450
- 2017. European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS). Redox Biology. 13: 94-162. doi: 10.1016/j.redox.2017.05.007
- 2016. Quantitative proteomics analysis of zebrafish exposed to sub-lethal dosages of β-methyl-amino-L-alanine (BMAA). Scientific Reports. 6:29631. doi: 10.1038/srep29631
- 2015. Algal toxin azaspiracid-1 induces early neuronal differentiation and alters peripherin isoform stoichiometry. Marine Drugs. 13: 7390-7402. doi: 10.3390/md13127072
- 2015. Redox control of protein degradation. Redox Biology. 6: 409-420. doi: 10.1016/j.redox.2015.07.003
- 2015. The N-terminal acetyltransferase Naa10 is essential for zebrafish development. Bioscience Reports. 35:00249. 10 pages. doi: 10.1042/BSR20150168
- 2013. Comparative analysis of IgM sub-variants in salmonid fish and identification of a residue in mu 3 which is essential for MAb4C10 reactivity. Fish and Shellfish Immunology. 34: 667-672. doi: 10.1016/j.fsi.2012.12.006
- 2013. Identification of dynamic changes in proteins associated with the cellular cytoskeleton after exposure to okadaic acid. Marine Drugs. 11: 1763-1782. doi: 10.3390/md11061763
- 2012. Nodularin exposure induces SOD1 phosphorylation and disrupts SOD1 co-localization with actin filaments. Toxins. 4: 1482-1499. doi: 10.3390/toxins4121482
- 2012. Ectopic expression of Flt3 kinase inhibits proliferation and promotes cell death in different human cancer cell lines. Cell Biology and Toxicology. 28: 201-212. doi: 10.1007/s10565-012-9216-z
- 2012. Dietary lysine imbalance affects muscle proteome in zebrafish (Danio rerio): a comparative 2D-DIGE study. Marine Biotechnology. 14: 643-654. doi: 10.1007/s10126-012-9462-3
- 2012. Impact of dietary protein hydrolysates on skeleton quality and proteome in Diplodus sargus larvae. Journal of Applied Ichthyology. 28: 477-487. doi: 10.1111/j.1439-0426.2012.01986.x
- 2010. Increased interaction between DJ-1 and the Mi-2/nucleosome remodelling and deacetylase complex during cellular stress. Proteomics. 10: 1494-1504. doi: 10.1002/pmic.200900586
- 2009. Acyloxymethyl esterification of Nodularin-R and Microcystin-LA produces inactive protoxins that become reactivated and produce apoptosis inside intact cells. Journal of Medicinal Chemistry. 52: 5758-5762. doi: 10.1021/jm900502e
- 2009. Proteomic response of human neuroblastoma cells to azaspiracid-1. Journal of Proteomics. 72: 695-707. doi: 10.1016/j.jprot.2009.02.008
- 2009. Ligand-induced Flt3-downregulation modulates cell death associated proteins and enhances chemosensitivity to idarubicin in THP-1 acute myeloid leukemia cells. Leukemia Research. 33: 276-287. doi: 10.1016/j.leukres.2008.06.029
- 2008. Identification of protein interaction partners by immunoprecipitation: Possible pitfalls and false positives. Experimental and Clinical Hepatology. 4: 16-22.
- 2008. Identification of a novel phosphorylation site of acyl-CoA binding protein (ACBP) in nodularin-induced apoptotic hepatocytes. Experimental Cell Research. 314: 2141-2149. doi: 10.1016/j.yexcr.2008.03.014
- 2007. Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv. Proteomics. 7: 1702-1718. doi: 10.1002/pmic.200600853
- 2006. Proteomic tissue imaging for rapid brain biomarker discovery. European Journal of Neurology. 13: 42-42.
- 2006. CaM-kinasell-dependent commitment to microcystin-induced apoptosis is coupled to cell budding, but not to shrinkage or chromatin hypercondensation. Cell Death and Differentiation. 13: 1191-1202. doi: 10.1038/sj.cdd.4401798
- 2006. Proteomics approaches to elucidate oncogenic tyrosine kinase signaling in myeloid malignancies. Current Pharmaceutical Biotechnology. 7: 185-198. doi: 10.2174/138920106777549696
- 2006. Algal toxins as guidance to identify phosphoproteins with key roles in apoptotic cell death. Current Pharmaceutical Biotechnology. 7: 209-215. doi: 10.2174/138920106777549704
- 2004. Caspase-dependent, geldanamycin-enhanced cleavage of co-chaperone p23 in leukemic apoptosis. Leukemia. 18: 1989-1996.
- 2003. PROBE-nasjonal plattform i proteomikk. NBS-nytt. 2: 23-24.
- 2003. Changed energy state and increased mitochondrial beta-oxidation rate in liver of rats associated with lowered proton electrochemical potential and stimulated uncoupling protein 2 (UCP-2) expression. Journal of Biological Chemistry. 278: 30525-30533.
- 2003. Changed Energy State and Increased Mitochondrial B-Oxidation Rate in Liver of Rats Associated with Lowered Proton Electrochemical Potential and Stimulated Uncoupling Protein 2 (UCP-2) Expression. Journal of Biological Chemistry. 278: 30525-30533.
- 2002. Ca2+/calmodulin dependent protein kinase II is required for microcystin-induced apoptosis. Journal of Biological Chemistry. 277: 2804-2811.
- 2001. Biologisk baserte blåskjelltester (BBB). Fiskehelse. 2. 26-33.
- 2001. Apoptotic effect of cyanobacterial extract on rat hepatocytes and human lymphocytes. Environmental Toxicology. 16: 225-233.
- 2001. Apoptotic effect of cyanobacterial blooms collected from Polish water reservoirs. International Journal of Occupational Medicine and Environmental Health. 13: 335-344.
- 2000. An ultrasensitive competitive binding assay for the detection of protein phosphatase directed toxins. Toxicon. 38: 347-360.
- 1999. Ultrarapid apoptosis inducted by phosphatase inhibitors. Cell Death Differ. Cell Death and Differentiation. 6: 1099-1108.
- 1999. Caspase I related protease inhibition retards the execution of okadaic acid and camptothecin induced apoptosis and PAI-2 selective cleavage, but not commitment to cell death in HL-60 cells. British Journal of Cancer. 79: 1685-1691.
- 1999. An ultrasensitive competitive binding assay for the detection of toxins affecting protein phosphatases. Toxicon. 38: 347-360.
- 1998. Apoptosis induced by microinjection of cytochrome c is caspase-dependent and is inibited by Bcl-2. Cell Death and Differentiation. 5: 660-668.
- 1998. Sensitive detection of apoptogenic toxins in suspension cultures of rat and salmon hepatocytes. Toxicon. 36: 1101-1114.
- 1997. Fas/APO-1 (CD95)-Induced Apoptosis of Primary Hepatocytes Is Inhibited by cAMP. Biochemical and Biophysical Research Communications - BBRC. 232: 20-25.
- 1997. Gap junctions and growth control in liver regeneration and in isolated rat hepatocytes. Hepatology. 25: 847-855.
- 1995. Ala%3%3%5 is essential for high-affinity cAMP-binding of both sites A and B of cAMP-dependent protein kinase type I. FEBS Letters. 362: 291-294.
- 1995. ALA-335 is essential for high-affinity cAMP-binding of both sites A and B of cAMP-dependent protein kinase type I. FEBS Letters. 362: 291-294.
Reports and theses
- 2006. Shellfish toxin azaspiracid-1 induced changes in cytoskeletal proteins in neuronal cells. Institute of Marine Research, Matre Research Station,, Institute of Marine Research and University of Bergen. 28 pages.
- 2006. Oocyte development in Atlantic cod (Gadus morhua L.): Trypsin-like specific activity, capacity for protein synthesis and proteomics. Institute of Marine Research, Matre Research Station,, Institute of Marine Research and University of Bergen. 29 pages.
- 1998. Hepatocyte proliferation and apoptosis-regulation by cell communication and phosphorylation. Dr.scient.. -.
Book sections
- 2014. Proteomic tools to elucidate the molecular action of micro-algal toxins. Chapter 7, pages 196-216. In:
- 2014. Toxins and Biologically Active Compounds from Microalgae, Volume 2. CRC Press. 700 pages. ISBN: 9781482231465.
More information in national current research information system (CRIStin)