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Karianne Fjeld

Researcher
  • E-mailKarianne.Fjeld@uib.no
  • Phone+47 55 97 70 32+47 924 29 152
  • Visitor Address
    Haukeland Universitetssykehus Laboratoriebygget, 7. etg. Heis øst
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • Oracz, Grzegorz; Kujko, Aleksandra Anna; Fjeld, Karianne; Wertheim-Tysarowska, Katarzyna; Adamus-Bialek, Wioletta; Steine, Solrun; Koziel, Dorota; Gluszek, Stanislaw; Molven, Anders; Rygiel, Agnieszka Magdalena. 2019. The hybrid allele 1 of carboxyl-ester lipase (CEL-HYB1) in Polish pediatric patients with chronic pancreatitis. Pancreatology (Print). 531-534.
  • el Jellas, Khadija; Johansson, Bente Berg; Fjeld, Karianne; Antonopoulos, Aristotelis; Immervoll, Heike; Choi, Man Hung; Hoem, Dag; Lowe, Mark E.; Lombardo, Dominique; Njølstad, Pål Rasmus; Dell, Anne; Mas, Eric; Haslam, Stuart M.; Molven, Anders. 2018. The mucinous domain of pancreatic carboxyl-ester lipase (CEL) contains core 1/core 2 O-glycans that can be modified by ABO blood group determinants. Journal of Biological Chemistry. 19476-19491.
  • Johansson, Bente Berg; Fjeld, Karianne; Solheim, Marie Holm; Shirakawa, Jun; Zhang, Enming; Keindl, Magdalena; Hu, Jiang; Lindqvist, Andreas; Døskeland, Anne Marie Simonne; Mellgren, Gunnar; Flatmark, Torgeir; Njølstad, Pål Rasmus; Kulkarni, Rohit N.; Wierup, Nils; Aukrust, Ingvild; Bjørkhaug, Lise. 2017. Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation. Molecular and Cellular Endocrinology. 146-157.
  • Dalva, Monica; el Jellas, Khadija; Steine, Solrun; Johansson, Bente Berg; Ringdal, Monika; Torsvik, Janniche; Immervoll, Heike; Hoem, Dag; Laemmerhirt, Felix; Simon, Peter; Lerch, Markus M.; Johansson, Stefan; Njølstad, Pål Rasmus; Weiss, Frank Ulrich; Fjeld, Karianne; Molven, Anders. 2017. Copy number variants and VNTR length polymorphisms of the carboxyl-ester lipase (CEL) gene as risk factors in pancreatic cancer. Pancreatology (Print). 83-88.
  • Fjeld, Karianne; Beer, Sebastian; Johnstone, Marianne; Zimmer, Constantin; Mössner, Joachim; Ruffert, Claudia; Krehan, Mario; Zapf, Christian; Njølstad, Pål Rasmus; Johansson, Stefan; Bugert, Peter; Miyajima, Fabio; Liloglou, Triantafillos; Brown, Laura J.; Winn, Simon A.; Davies, Kelly; Latawiec, Diane; Gunson, Bridget K.; Criddle, David N.; Pirmohamed, Munir; Grützmann, Robert; Michl, Patrick; Greenhalf, William; Molven, Anders; Sutton, Robert; Rosendahl, Jonas. 2016. Length of variable numbers of tandem repeats in the carboxyl ester lipase (CEL) gene may confer susceptibility to alcoholic liver cirrhosis but not alcoholic chronic pancreatitis. PLOS ONE.
  • Kolar, Matthew J.; Kamat, Siddhesh S.; Parsons, William H.; Homan, Edwin A.; Maher, Tim; Peroni, Odile D.; Syed, Ismail; Fjeld, Karianne; Molven, Anders; Kahn, Barbara B.; Cravatt, Benjamin F.; Saghatelian, Alan. 2016. Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase. Biochemistry. 4636-4641.
  • Irgens, Henrik Underthun; Fjeld, Karianne; Johansson, Bente Berg; Ringdal, Monika; Immervoll, Heike; Leh, Sabine Maria; Søvik, Oddmund; Johansson, Stefan; Molven, Anders; Njølstad, Pål Rasmus. 2015. Glycogenin-2 is dispensable for liver glycogen synthesis and glucagon-stimulated glucose release. Journal of Clinical Endocrinology and Metabolism. E767-E775.
  • Fjeld, Karianne; Weiss, Frank Ulrich; Lasher, Denise; Rosendahl, Jonas; Chen, Jian-Min; Johansson, Bente Berg; Kirsten, Holger; Ruffert, Claudia; Masson, Emmanuelle; Steine, Solrun; Bugert, Peter; Cnop, Miriam; Grützmann, Robert; Mayerle, Julia; Mössner, Joachim; Ringdal, Monika; Schulz, Hans-Ulrich; Sendler, Matthias; Simon, Peter; Sztromwasser, Pawel Szymon; Torsvik, Janniche; Scholz, Markus; Tjora, Erling; Férec, Claude; Witt, Heiko; Lerch, Markus M.; Njølstad, Pål Rasmus; Johansson, Stefan; Molven, Anders. 2015. A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis. Nature Genetics. 518-522.
  • Torsvik, Janniche; Johansson, Bente Berg; Dalva, Monica; Marie, Michael Bruno Eric; Fjeld, Karianne; Johansson, Stefan; Bjørkøy, Geir; Saraste, Jaakko; Njølstad, Pål Rasmus; Molven, Anders. 2014. Endocytosis of secreted carboxyl ester lipase in a syndrome of diabetes and pancreatic exocrine dysfunction. Journal of Biological Chemistry. 29097-29111.
  • Ragvin, Anja; Fjeld, Karianne; Weiss, F. Ulrich; Torsvik, Janniche; Aghdassi, Ali; Mayerle, Julia; Simon, Peter; Njølstad, Pål Rasmus; Lerch, Markus M.; Johansson, Stefan; Molven, Anders. 2013. The number of tandem repeats in the carboxyl-ester lipase (CEL) gene as a risk factor in alcoholic and idiopathic chronic pancreatitis. Pancreatology (Print). 29-32.
  • Johansson, Bente Berg; Torsvik, Janniche; Bjørkhaug, Lise; Vesterhus, Mette; Ragvin, Anja; Tjora, Erling; Fjeld, Karianne; Hoem, Dag; Johansson, Stefan; Ræder, Helge; Lindquist, Susanne; Hernell, Olle; Cnop, Miriam; Saraste, Jaakko; Flatmark, Torgeir; Molven, Anders; Njølstad, Pål Rasmus. 2011. Diabetes and pancreatic exocrine dysfunction due to mutations in the carboxyl ester lipase gene-maturity onset diabetes of the young (CEL-MODY) A PROTEIN MISFOLDING DISEASE. Journal of Biological Chemistry. 34593-34605.
  • Fjeld, Karianne; Kettunen, Paivi; Furmanek, Tomasz Michal; Kvinnsland, Inger Rebekka Hals; Luukko, Keijo. 2005. Dynamic expression of Wnt signaling-related Dickkopf1,-2, and-3 mRNAs in the developing mouse tooth. Developmental Dynamics. 161-166.
  • Nie, Xuguang; Luukko, Keijo; Fjeld, Karianne; Kvinnsland, Inger Rebekka Hals; Kettunen, Paivi. 2005. Developmental expression of Dkk1-3 and Mmp9 and apoptosis in cranial base of mice. Journal of Molecular Histology. 419-426.
  • Kettunen, Paivi; Løes, Sigbjørn Suk; Furmanek, Tomasz Michal; Fjeld, Karianne; Kvinnsland, Inger Rebekka Hals; Behar, Oded; Yagi, Takeshi; Fujisawa, Hajime; Vainio, Seppo; Taniguchi, Masahiko; Luukko, Keijo. 2005. Coordination of trigeminal axon navigation and patterning with tooth organ formation: epithelial-mesenchymal interactions, and epithelial Wnt4 and Tgfβ1 regulate semaphorin 3a expression in the dental mesenchyme. Development. 323-334.
  • Kvinnsland, Inger Hals; Luukko, Keijo Aukusti; Fristad, Inge; Kettunen, Paivi; Jackson, DL; Fjeld, Karianne; von Bartheld, CS; Byers, MR. 2004. Glial cell line-derived neurotrophic factor (GDNF) from adult rat tooth serves a distinct population of large-sized trigeminal neurons. European Journal of Neuroscience. 2089-2098.
  • Fristad, Inge; Vandevska-Radunovic, Vaska; Fjeld, Karianne; Wimalawansa, SJ; Hals Kvinnsland, Inger. 2003. NK1-, NK2-, NK3-, and CGRP1-receptors identified in rat oral soft tissues, bone- and hard tissue cells. Cell and Tissue Research. 383-391.
  • Luukko, Keijo Aukusti; Loes, Sigbjorn; Furmanek, Tomasz; Fjeld, Karianne; Hals Kvinnsland, Inger; Kettunen, Paivi Johanna. 2003. Identification of a novel putative signaling center, the tertiary enamel knot in the postnatal mouse molar tooth. Mechanisms of Development. 270-276.
  • Luukko, Keijo; Løes, Sigbjørn Suk; Furmanek, Tomasz; Fjeld, Karianne; Kvinnsland, Inger Hals; Kettunen, Paivi. 2003. Identification of a novel putative signaling center, the tertiary enamel knot in the postnatal mouse molar tooth. Mechanisms of Development. 270-276.
Academic lecture
  • Fjeld, Karianne; Kettunen, Paivi Johanna; Luukko, Keijo Aukusti; Hals Kvinnsland, Inger. 2003. Wnt signaling in tooth morphogenesis.
  • Fjeld, Karianne; Luukko, Keijo Aukusti; Kettunen, Paivi Johanna; Hals Kvinnsland, Inger. 2003. Functions of SLIT1 in tooth morphogenesis.
Editorial
  • Molven, Anders; Fjeld, Karianne; Lowe, Mark E. 2016. Lipase genetic variants in chronic pancreatitis: when the end is wrong, all's not well. Gastroenterology. 1515-1518.
Thesis at a second degree level
  • Fjeld, Karianne. 2000. The effect of beta1-integins on the phenotype of human gliomas.
  • Fjeld, Karianne. 2000. The effect of Beta1-integrins on the invasive phenotype of human gliomas.
Feature article
  • Fjeld, Karianne; Molven, Anders. 2015. Du vet nesten ingenting om det, men dette er et av kroppens mest sentrale organer. Aftenposten (morgenutg. : trykt utg.).
Doctoral dissertation
  • Fjeld, Karianne. 2006. The Wnt pathway. Studies on Wnt signaling and regulation in the developing tooth.
Interview
  • Kettunen, Paivi; Luukko, Keijo Aukusti; Fjeld, Karianne; Kvinnsland, Inger Hals; Pletten, Christina. 2004. Dyrking av det Perfekte Smil.
Abstract
  • Molven, Anders; Torsvik, Janniche; Johansson, Bente Berg; Marie, Michael Bruno Eric; Fjeld, Karianne; Johansson, Stefan; Saraste, Jaakko; Njølstad, Pål Rasmus. 2013. Cellular re-uptake of secreted carboxyl-ester lipase protein in CEL-MODY, a syndrome of diabetes and pancreatic exocrine dysfunction. Diabetologia. S152-S152.
  • Fjeld, Karianne; Torsvik, Janniche; Johansson, Stefan; Ek, Jakob; Flanagan, Sarah E.; Johansen, Anders; Ræder, Helge; Pedersen, Oluf; Hattersley, Andrew T.; Hansen, Torben; Molven, Anders; Njølstad, Pål Rasmus. 2008. Structural changes in the repeated region of the carboxyl-ester lipase (CEL) gene and the development of diabetes. Diabetologia. S123-S123.
Academic literature review
  • Johansson, Bente Berg; Fjeld, Karianne; el Jellas, Khadija; Gravdal, Anny; Valvatne, Monica Dalva; Tjora, Erling; Ræder, Helge; Kulkarni, Rohit Rajesh; Johansson, Stefan; Njølstad, Pål Rasmus; Molven, Anders. 2018. The role of the carboxyl ester lipase (CEL) gene in pancreatic disease. 12-19.
Article in business/trade/industry journal
  • Valvatne, Monica Dalva; el Jellas, Khadija; Gravdal, Anny; Njølstad, Pål Rasmus; Fjeld, Karianne; Molven, Anders; Lugea, Aurelia; Pandol, Stephen J; Waldron, Richard T; Lavik, Ida. 2020. Pathogenic Carboxyl Ester Lipase (CEL) Variants Interact with the Normal CEL Protein in Pancreatic Cells . Cells.

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