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  • E-mailLars.Bo@uib.no
  • Phone+47 55 97 61 86
  • Visitor Address
    Haukeland Universitetssykehus Laboratoriebygget, 7. etg. Heis øst
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • Stokke, Silje Agnethe; Lehmann, Anne Kristine; Trovik, Linn; Kristoffersen, Einar Klæboe; Bø, Lars; Myhr, Kjell-Morten; Torkildsen, Øivind. 2019. Safety and efficacy of autologous hematopoietic stem cell transplantation for multiple sclerosis in Norway. Multiple Sclerosis. 1-9.
  • Nystad, Agnes Elisabeth; Lereim, Ragnhild Reehorst; Wergeland, Stig; Oveland, Eystein; Myhr, Kjell-Morten; Bø, Lars; Torkildsen, Øivind. 2019. Fingolimod downregulates brain sphingosine-1-phosphate receptor 1 levels but does not promote remyelination or neuroprotection in the cuprizone model. Journal of Neuroimmunology.
  • Holmøy, Trygve; Fevang, Børre; Olsen, David Benee; Spigset, Olav; Bø, Lars. 2019. Adverse events with fatal outcome associated with alemtuzumab treatment in multiple sclerosis. BMC Research Notes. 1-5.
  • Svendsen, Bjørn; Grytten, Nina ; Bø, Lars; Aarseth, Hallvard Gilje; Smedal, Tori; Myhr, Kjell-Morten. 2018. The economic impact of multiple sclerosis to the patients and their families in Norway. European Journal of Health Economics. 1243-1257.
  • Lunde, Hanne Marie; Assmus, Jörg; Myhr, Kjell-Morten; Bø, Lars; Grytten, Nina. 2017. Survival and cause of death in multiple sclerosis: A 60-year longitudinal population study. Journal of Neurology, Neurosurgery and Psychiatry. 621-625.
  • Torkildsen, Øivind; Myhr, Kjell-Morten; Bø, Lars. 2016. Disease-modifying treatments for multiple sclerosis – a review of approved medications. European Journal of Neurology. 18-27.
  • Fjær, Sveinung; Bø, Lars; Myhr, Kjell-Morten; Torkildsen, Øivind; Wergeland, Stig. 2015. Magnetization transfer ratio does not correlate to myelin content in the brain in the MOG-EAE mouse model. Neurochemistry International. 28-40.
  • Alme, Maria Nordheim; Nystad, Agnes Elisabeth; Bø, Lars; Myhr, Kjell-Morten; Vedeler, Christian A.; Wergeland, Stig; Torkildsen, Øivind. 2015. Fingolimod does not enhance cerebellar remyelination in the cuprizone model. Journal of Neuroimmunology. 180-186.
  • Lunde, Hanne Marie; Telstad, Wenche; Grytten, Nina Agnethe; Kyte, Lars; Aarseth, Jan; Myhr, Kjell-Morten; Bø, Lars. 2014. Employment among patients with multiple sclerosis-A population study. PLOS ONE.
  • Nystad, Agnes Elisabeth; Wergeland, Stig; Aksnes, Lage; Myhr, Kjell-Morten; Bø, Lars; Torkildsen, Øivind. 2014. Effect of high-dose 1.25 dihydroxyvitamin D3 on remyelination in the cuprizone model. APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 1178-1186.
  • Fjær, Sveinung; Bø, Lars; Lundervold, Arvid; Myhr, Kjell-Morten; Pavlin, Tina; Torkildsen, Øivind; Wergeland, Stig. 2013. Deep gray matter demyelination detected by magnetization transfer ratio in the cuprizone model. PLOS ONE.
  • Wergeland, Stig; Torkildsen, Øivind; Myhr, Kjell-Morten; Mørk, Sverre; Bø, Lars. 2012. The cuprizone model: regional heterogeneity of pathology. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 648-657.
  • Lunde, Hanne Marie; Aae, Tommy Frøseth; Indrevåg, William; Aarseth, Jan Harald; Bjorvatn, Bjørn; Myhr, Kjell-Morten; Bø, Lars. 2012. Poor Sleep in Patients with Multiple Sclerosis. PLOS ONE. 5 pages.
  • Myhr, Kjell-Morten; Grytten, Nina Agnethe; Torkildsen, Øivind; Wergeland, Stig; Bø, Lars; Pugliatti, M; Aarseth, Jan Harald. 2012. A need for national registries and international collaborative research in multiple sclerosis. Acta Neurologica Scandinavica. 1-3.
  • Wergeland, Stig; Torkildsen, Øivind; Myhr, Kjell-Morten; Aksnes, Lage; Mørk, Sverre; Bø, Lars. 2011. Dietary vitamin D3 supplements reduce demyelination in the cuprizone model. PLOS ONE. 8 pages.
  • Torkildsen, Øivind Fredvik; Stansberg, Christine; Angelskår, Solveig Mjelstad; Kooi, Evert-Jan; Geurts, Jeroen J.G.; van der Valk, Paul; Myhr, Kjell-Morten; Steen, Vidar Martin; Bø, Lars. 2010. Upregulation of immunoglobulin-related genes in cortical sections from multiple sclerosis patients. Brain Pathology. 720-729.
  • Tallantyre, Emma C.; Bø, Lars; Al-Rawashdeh, Omar; Owens, Trudy; Polman, Chris H.; Lowe, James; Evangelou, Nikos. 2010. Clinico-pathological evidence that axonal loss underlies disability in progressive multiple sclerosis. Multiple Sclerosis. 406-411.
  • Gilmore, Christopher P.; Geurts, Jeroen J.G.; Evangelou, Nikos; Bot, Joost C.J.; van Schijndel, Ronald A.; Pouwels, Petra J.W ; Barkhof, Frederik; Bø, Lars. 2009. Spinal cord grey matter lesions in multiple sclerosis detected by post-mortem high field MR imaging. Multiple Sclerosis. 180-188.
  • Gilmore, Christopher P.; DeLuca, GC; Bø, Lars; Owens, Trudy; Lowe, James; Esiri, MM; Evangelou, Nikos. 2009. Spinal Cord Neuronal Pathology in Multiple Sclerosis. Brain Pathology. 642-649.
  • Gilmore, Christopher P.; Donaldson, I; Bø, Lars; Owens, Trudy; Lowe, J; Evangelou, Nikos. 2009. Regional variations in the extent and pattern of grey matter demyelination in multiple sclerosis: a comparison between the cerebral cortex, cerebellar cortex, deep grey matter nuclei and the spinal cord. Journal of Neurology, Neurosurgery and Psychiatry. 182-187.
  • Kooi, Evert-Jan; Geurts, Jeroen J.G.; van Horssen, Jack; Bø, Lars; van der Valk, Paul. 2009. Meningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 1021-1028.
  • Tallantyre, Emma C.; Bø, Lars; Al-Rawashdeh, Omar; Owens, Trudy; Polman, Chris H.; Lowe, James; Evangelou, Nikos. 2009. Greater loss of axons in primary progressive multiple sclerosis plaques compared to secondary progressive disease. Brain. 1190-1199.
  • Witte, Maarten; Bø, Lars; Rodenburg, Richard J.; Belien, Jeroen A.; Musters, Rene; Hazes, Thierry; Wintjes, Liesbeth T.; Smeitink, Jan A.; Geurts, Jeroen J.G.; de Vries, Helga E.; van der Valk, Paul; van Horssen, Jack. 2009. Enhanced number and activity of mitochondria in multiple sclerosis lesions. Journal of Pathology. 193-204.
  • Torkildsen, Øivind Fredvik; Brunborg, Linn Anne; Thorsen, Frits Alan; Mørk, Sverre; Stangel, Martin; Myhr, Kjell-Morten; Bø, Lars. 2009. Effects of dietary intervention on MRI activity, de- and remyelination in the cuprizone model for demyelination. Experimental Neurology. 160-166.
  • Kooi, Evert-Jan; van Horssen, Jack; Witte, Maarten; Amor, Sandra; Bø, Lars; Dijkstra, Christine D.; van der Valk, Paul; Geurts, Jeroen J.G. 2009. Abundant extracellular myelin in the meninges of patients with multiple sclerosis. Neuropathology and Applied Neurobiology. 283-295.
  • Torkildsen, Øivind Fredvik; Brunborg, Linn Anne; Milde, Anne Marita; Mørk, Sverre; Myhr, Kjell-Morten; Bø, Lars. 2009. A salmon based diet protects mice from behavioural changes in the cuprizone model for demyelination. Clinical Nutrition. 83-87.
  • Torkildsen, Øivind Fredvik; Brunborg, Linn Anne Bjelland; Myhr, Kjell-Morten; Bø, Lars. 2008. The cuprizone model for demyelination. Acta Neurologica Scandinavica. 72-76.
  • Couturier, Nicholas; Zappulla, Jacques P.; Lauwers-Cances, Valérie; Uro-Coste, Emmanuelle; Delisle, Marie-Bernadette; Clanet, Michel; Montagne, Lisette; van der Valk, Paul; Bø, Lars; Liblau, Roland S. 2008. Mast cell transcripts are increased within and outside multiple sclerosis lesions. Journal of Neuroimmunology. 176-185.
  • Breij, Esther C.W.; Brink, Bianca P.; Veerhuis, Rob; Van den Berg, Christa; Vloet, Rianka; Yan, Riqiang; Dijkstra, Christine D.; van der Valk, Paul; Bø, Lars. 2008. Homogeneity of active demyelinating lesions in established multiple sclerosis. Annals of Neurology. 16-25.
  • van Horssen, Jack; Brink, Bianca P.; de Vries, Helga E.; van der Valk, Paul; Bø, Lars. 2007. The blood-brain barrier in cortical multiple sclerosis lesions. Journal of Neuropathology and Experimental Neurology. 321-328.
  • Bø, Lars; Geurts, Jeroen J.G.; van der Valk, Paul; Polman, Chris; Barkhof, Frederik. 2007. Lack of correlation between cortical demyelination and white matter pathologic changes in multiple sclerosis. Archives of Neurology. 76-80.
  • Geurts, Jeroen J.G.; Bö, Lars; Roosendaal, Stefan D; Hazes, Thierry; Daniëls, Richard; Barkhof, Frederik; Witter, Menno P; Huitinga, Inge; van der Valk, Paul. 2007. Extensive hippocampal demyelination in multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 819-827.
  • Bø, Lars; Mørk, Sverre; Geurts, Jeroen J.G.; van der Valk, Paul. 2006. Grey matter pathology in multiple sclerosis. Acta Neurologica Scandinavica. 48-50.
  • Bø, Lars; Vedeler, C.; Nyland, Harald Inge; Trapp, Bruce D.; Mørk, Sverre. 2003. Subpial demyelination in the cerebral cortex of multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 723-732.
  • Bø, Lars; Vedeler, C.; Nyland, Harald Inge; Trapp, B.D.; Mørk, Sverre. 2003. Intracortical demyelination in multiple sclerosis is not associated with increased lymphocyte infiltration. Mult Scler. 323-331.
  • Peterson, J.W; Bø, Lars; Mørk, Sverre; Chang, A; Ransohoff, RM; Trapp, B.D. 2002. VCAM-1-positive microglia target oligodendrycytes at the border of multiple sclerosis lesions. Journal of Neuropathology and Experimental Neurology. 539-546.
  • Romi, Fredrik; Bø, Lars; Skeie, Geir Olve; Myking, Andreas O.; Aarli, Johan Arild; Gilhus, Nils Erik. 2002. Titin and ryanodine receptor epitopes are expressed in cortical thymoma along with co-stimulatory molecules. Journal of Neuroimmunology. 82-89.
  • Peterson, John W.; Bø, Lars; Mørk, Sverre; Chang, Ansi; Trapp, Bruce D. 2001. Transected Neurites, Apoptotic Neurons and Reduced Inflammation in Cortical MS Lesions. Annals of Neurology. 389-400.
  • Trapp, BD; Bø, Lars; Mørk, Sverre; Chang, A. 1999. Pathogenesis of tissue injury in MS lesions. Neuroimmunomodulation. 49-56.
Popular scientific lecture
  • Bø, Lars. 2001. Multippel sklerose: sykdomsmekanismer.
Academic lecture
  • Romi, Fredrik; Bø, Lars; Skeie, Geir Olve; Myking, Andreas O.; Aarli, Johan Arild; Gilhus, Nils Erik. 2002. Titin and ryanodine receptor epitopes are expressed in cortical thymoma along with co-stimulatory molecules.
  • Bø, Lars. 2001. Normal appearing cortical tissue, pathology studies.
  • Bø, Lars. 2001. Differences in pathology between secondary and primary multiple sclerosis.
Reader opinion piece
  • Holmøy, Trygve; Myhr, Kjell-Morten; Bø, Lars. 2014. Re: Uetisk av nevrologene ikke å tilby pasienter med multippel sklerose cytostatikabehandling med autolog stamcellestøtte. Tidsskrift for Den norske legeforening. 2239-2240.
Short communication
  • Lunde, Hanne Marie; Torkildsen, Øivind; Bø, Lars; Kjørsvik, Anne. 2016. Botulinum Toxin as Monotherapy in Symptomatic Trigeminal Neuralgia. Headache. 1035-1039.
Doctoral dissertation
  • Lunde, Hanne Marie Bøe. 2017. Patient-centered outcomes in multiple sclerosis. Results from observational studies on sleep, employment and survival.
  • Bø, Lars. 1998. Multiple sclerosis, immunopathological studies of inflammatory control nervous system demyelination. -.
Academic chapter/article/Conference paper
  • Myhr, Kjell-Morten; Torkildsen, Øivind; Bø, Lars. 2014. Multippel Sklerose. 10 pages.
Abstract
  • Lunde, Hanne Marie; Aae, Tommy F; Indrevåg, William; Aarseth, Jan Harald; Myhr, Kjell-Morten; Bjorvatn, Bjarne; Bø, Lars. 2012. Poor sleep in patients with multiple sclerosis. European Journal of Neurology. 706-706.
  • Witte, Maarten; Bø, Lars; Rodenburg, Richard J.; Belien, JA; Musters, Rene; Smeitink, Jan A.; Geurts, J; de Vries, Helga E.; van der Valk, Paul; Horssen, J. 2009. MITOCHONDRIAL ALTERATIONS IN ASTROCYTES IN MS LESIONS. Glia. S134-S134.
  • Wergeland, Stig; Torkildsen, Øivind Fredvik; Myhr, Kjell-Morten; Mørk, Sverre; Bø, Lars. 2009. Histopathological characterisation of the cuprizone model for demyelination. Multiple Sclerosis. S177-S177.
  • Tallantyre, Emma C.; Bø, Lars; Lowe, James; Evangelou, Nikos. 2009. Equal loss of corticospinal axons despite less demyelination in primary vs secondary progressive multiple sclerosis. Neuropathology and Applied Neurobiology. 17-18.
  • Kooi, Evert-Jan; Bø, Lars; van Horssen, Jack; Geurts, Jeroen J.G.; van der Valk, Paul. 2008. Meningeal inflammation in multiple sclerosis. Multiple Sclerosis. S273-S274.
  • Torkildsen, Øivind Fredvik; Brunborg, Linn Anne Bjelland; Milde, Anne Marita; Myhr, Kjell-Morten; Bø, Lars. 2008. Fish diet prevents impaired mobility in the murine cuprizone model for multiple sclerosis. Multiple Sclerosis. S90-S91.
  • Kooi, Evert-Jan; van Horssen, Jack; Witte, Maarten; Amor, Sandra; Bø, Lars; Dijkstra, Christine D.; van der Valk, Paul; Geurts, Jeroen J.G. 2008. Extensive myelin deposition in the meninges of patients with multiple sclerosis. Multiple Sclerosis. S273-S273.
  • Breij, Esther C.W.; Brink, Bianca P.; Veerhuis, Rob; Van den Berg, Christa; Vloet, Rianka; Yan, Riqiang; Dijkstra, Christine D.; van der Valk, Paul; Bø, Lars. 2008. A homogeneous pattern of active demyelination in patients with established multiple sclerosis. Journal of Neuroimmunology. 264-265.
Poster
  • Fjær, Sveinung; Wergeland, Stig; Bø, Lars. 2014. Magnetization transfer ratio (MTR) increased unexpectedly in EAE induced mice.
Academic literature review
  • Myhr, Kjell-Morten; Torkildsen, Øivind; Lossius, Peter Andreas Vold; Bø, Lars; Holmøy, Trygve. 2019. B cell depletion in the treatment of multiple sclerosis. 261-271.
  • Myhr, Kjell-Morten; Grytten, Nina ; Torkildsen, Øivind; Wergeland, Stig; Bø, Lars; Aarseth, Jan Harald. 2015. The Norwegian Multiple Sclerosis Registry and Biobank. 24-28.
  • Lunde, Hanne Marie; Bjorvatn, Bjørn; Myhr, Kjell-Morten; Bø, Lars. 2013. Clinical assessment and management of sleep disorders in multiple sclerosis: a literature review. 24-30.
  • Wergeland, Stig; Torkildsen, Øivind; Bø, Lars; Myhr, Kjell-Morten. 2012. Polyunsaturated fatty acids in multiple sclerosis therapy. 70-75.
  • Bø, Lars. 2009. The histopathology of grey matter demyelination in multiple sclerosis. 51-57.
Article in business/trade/industry journal
  • Hoff, Jana Midelfart; Dhayalan, Mauran; Midelfart, Anna; Tharaldsen, Ane Roushan; Bø, Lars. 2019. Synsproblemer ved multippel sklerose. Tidsskrift for Den norske legeforening. 7 pages.

More information in national current research information system (CRIStin)