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Lars Herfindal's picture
  • E-mailLars.Herfindal@uib.no
  • Phone+47 55 97 46 28+47 974 03 493
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • Åsrud, Kathrine Sivertsen; Pedersen, Line; Aesoy, Reidun; Muwonge, Haruna; Aasebø, Elise; Pettersen, Ina Katrine Nitschke; Herfindal, Lars; Dobie, Ross; Jenkins, Stephen; Berge, Rolf Kristian; Henderson, Neil Cowan; Selheim, Frode; Doskeland, Stein Ove; Bakke, Marit. 2019. Mice depleted for Exchange Proteins Directly Activated by cAMP (Epac) exhibit irregular liver regeneration in response to partial hepatectomy. Scientific Reports. 1-17.
  • Carpinteyro Diaz, Andrea Estefania; Herfindal, Lars; Rathe, Bendik Auran; Sletta, Kristine; Vedeler, Anni; Haavik, Svein; Fossen, Torgils. 2019. Cytotoxic saponins and other natural products from flowering tops of Narthecium ossifragum L. Phytochemistry. 67-77.
  • Humisto, Anu; Jokela, Jouni; Teigen, Knut; Wahlsten, Matti; Permi, Perttu; Sivonen, Kaarina; Herfindal, Lars. 2019. Characterization of the interaction of the antifungal and cytotoxic cyclic glycolipopeptide hassallidin with sterol-containing lipid membranes. Biochimica et Biophysica Acta - Biomembranes. 1510-1521.
  • Calisto, Rita; Sæbø, Eirik Færøy; Storesund, Julia Endresen; Øvreås, Lise; Herfindal, Lars; Lage, Olga M. 2019. Anticancer activity in Planctomycetes. Frontiers in Marine Science. 10 pages.
  • Ibrahim, Ayaan Hamdi Haji; Herfindal, Lars; Rathe, Bendik Auran; Andersen, Heidi Lie; Almeida, Jackson R. G. S.; Fossen, Torgils. 2019. A novel poly-oxygenated flavone glucoside from aerial parts of the Brazilian plant Neoglaziovia variegata (Bromeliaceae). Heliyon. 1-13.
  • Bjørnstad, Ronja; Aesoy, Reidun; Bruserud, Øystein; Brenner, Annette; Giraud, Francis; Dowling, Tara Helen; Gausdal, Gro; Moreau, Pascale; Doskeland, Stein Ove; Anizon, Fabrice; Herfindal, Lars. 2019. A kinase inhibitor with anti-Pim kinase activity is a potent and selective cytotoxic agent toward acute myeloid leukemia. Molecular Cancer Therapeutics. 567-578.
  • Bezem, Maria Teresa; Johannessen, Fredrik Gullaksen; K C, Kunwar Jung; Gundersen, Edvin Tang; Jorge Finnigan, Ana; Ying, Ming; Betbeder, Didier; Herfindal, Lars; Martinez, Aurora. 2018. Stabilization of Human Tyrosine Hydroxylase in Maltodextrin Nanoparticles for Delivery to Neuronal Cells and Tissue. Bioconjugate chemistry. 493-502.
  • Prandina, Anthony; Herfindal, Lars; Radix, Sylvie; Rongved, Pål; Doskeland, Stein Ove; Le Borgne, Marc; Perret, Florent. 2018. Enhancement of iodinin solubility by encapsulation into cyclodextrin nanoparticles. Journal of enzyme inhibition and medicinal chemistry (Print). 370-375.
  • Viktorsson, Elvar Örn; Grøthe, Bendik Melling; Aesoy, Reidun; Sabir, Misbah; Snellingen, Simen; Åstrand, Ove Alexander Høgmoen; Prandina, Anthony; Bonge-Hansen, Tore; Doskeland, Stein Ove; Herfindal, Lars; Rongved, Pål. 2017. Total synthesis and antileukemic evaluations of the phenazine 5,10-dioxide natural products iodinin, myxin and their derivatives. Bioorganic & Medicinal Chemistry. 2285-2293.
  • Nygaard, Gyrid; Herfindal, Lars; Sivertsen Åsrud, Kathrine; Bjørnstad, Ronja; Kopperud, Reidun Kristin; Oveland, Eystein; Berven, Frode; Myhren, Lene Elisabeth; Høivik, Erling Andre; Lunde, Turid Helen Felli; Bakke, Marit; Doskeland, Stein Ove; Selheim, Frode. 2017. Epac1-deficient mice have bleeding phenotype and thrombocytes with decreased GPIbβ expression. Scientific Reports. 1-15.
  • Evensen, Lasse; Lie Johansen, Patrick; Koster, Gerbrand; Zhu, Kaizheng; Herfindal, Lars; Speth, Martin; Fenaroli, Federico; Hildahl, Jon Paul; Fam, Shahla Bagheri; Tulotta, Claudia; Prasmickaite, Lina; Mælandsmo, Gunhild; Snaar-Jagalska, Ewa; Griffiths, Gareth Wyn. 2016. Zebrafish as a model system for characterization of nanoparticles against cancer. Nanoscale. 862-877.
  • Vu, Marita Hoang Anh; Herfindal, Lars; Juvik, Ole-Johan; Vedeler, Anni; Haavik, Svein; Fossen, Torgils. 2016. Toxic aromatic compounds from fruits of Narthecium ossifragum L. Phytochemistry. 76-85.
  • Humisto, Anu; Herfindal, Lars; Jokela, Jouni; Karkman, Antti; Bjørnstad, Ronja; Choudhury, Romi Roy; Sivonen, Kaarina. 2016. Cyanobacteria as a source for novel anti-leukemic compounds. Current Pharmaceutical Biotechnology. 78-91.
  • Giraud, Francis; Bourhis, Marion; Ebrahimi, Edris; Herfindal, Lars; Roy Choudhury, Romi; Bjørnstad, Ronja; Doskeland, Stein Ove; Anizon, Fabrice; Moreau, Pascale. 2015. Synthesis and activities of new indolopyrrolobenzodiazepine derivatives toward acute myeloid leukemia cells. Bioorganic & Medicinal Chemistry. 7313-7323.
  • Bouaziz, Zouhair; Issa, Samar; Gentili, Jacques; Gratz, Andreas; Bollacke, Andre; Kassack, Matthias; Jose, Joachim; Herfindal, Lars; Gausdal, Gro; Doskeland, Stein Ove; Mullié, Catherine; Sonnet, Pascal; Desgrouas, Camille; Taudon, Nicolas; Valdameri, Glaucio; Di Pietro, Attilio; Baitiche, Milad; Le Borgne, Marc. 2015. Biologically active carbazole derivatives: focus on oxazinocarbazoles and related compounds. Journal of enzyme inhibition and medicinal chemistry (Print). 180-188.
  • Nygaard, Gyrid; Herfindal, Lars; Kopperud, Reidun Kristin; Aragay, Anna M.; Holmsen, Holm A; Doskeland, Stein Ove; Kleppe, Rune; Selheim, Frode. 2014. Time-dependent inhibitory effects of cGMP-analogues on thrombin-induced platelet-derived microparticles formation, platelet aggregation, and P-selectin expression. Biochemical and Biophysical Research Communications - BBRC. 357-363.
  • Giraud, Francis; Bourhis, Marion; Nauton, Lionel; Théry, Vincent; Herfindal, Lars; Doskeland, Stein Ove; Anizon, Fabrice; Moreau, Pascale. 2014. New N-1,N-10 bridged pyrrolo[2,3-α]carbazole-3-carbaldehydes: synthesis and biological activities. Bioorganic chemistry (Print). 108-115.
  • Herfindal, Lars; Krakstad, Camilla; Myhren, Lene Elisabeth; Hagland, Hanne; Kopperud, Reidun Kristin; Teigen, Knut; Schwede, Frank; Kleppe, Rune; Doskeland, Stein Ove. 2014. Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3. PLOS ONE.
  • Myhren, Lene Elisabeth; Nilssen, Ida Mostrøm; Nicolas, Valérie; Doskeland, Stein Ove; Barratt, Gillian; Herfindal, Lars. 2014. Efficacy of multi-functional liposomes containing daunorubicin and emetine for treatment of acute myeloid leukaemia. European journal of pharmaceutics and biopharmaceutics.
  • Liu, Liwei; Herfindal, Lars; Jokela, Jouni; Shishido, Tania Keiko; Wahlsten, Matti; Doskeland, Stein Ove; Sivonen, Kaarina. 2014. Cyanobacteria from terrestrial and marine sources contain apoptogens able to overcome chemoresistance in acute myeloid leukemia cells. Marine Drugs. 2036-2053.
  • Sletta, Håvard; Degnes, Kristin Fløgstad; Herfindal, Lars; Klinkenberg, Geir; Fjærvik, Espen; Zahlsen, Kolbjørn; Brunsvik, Anders; Nygaard, Gyrid; Aachmann, Finn Lillelund; Ellingsen, Trond Erling; Doskeland, Stein Ove; Zotchev, Sergey. 2014. Anti-microbial and cytotoxic 1,6-dihydroxyphenazine-5,10-dioxide (iodinin) produced by Streptosporangium sp. DSM 45942 isolated from the fjord sediment. Applied Microbiology and Biotechnology. 603-610.
  • Prestegard, Siv Kristin; Knutsen, Gjert; Herfindal, Lars. 2014. Adenosine content and growth in the diatom Phaeodactylum tricornutum (Bacillariophyceae): effect of salinity, light, temperature and nitrate. Diatom Research. 361-369.
  • Prestegard, Siv Kristin; Knutsen, Gjert; Herfindal, Lars. 2014. Adenosine content and growth in the diatom Phaeodactylum tricornutum (Bacillariophyceae): effect of salinity, light, temperature and nitrate. Diatom Research. 361-369.
  • Liu, Liwei; Jokela, Jouni; Herfindal, Lars; Wahlsten, Matti; Sinkkonen, Jari; Permi, Perttu; Fewer, David P.; Doskeland, Stein Ove; Sivonen, Kaarina. 2014. 4-methylproline guided natural product discovery: co-occurrence of 4-hydroxy- and 4-methylprolines in nostoweipeptins and nostopeptolides. ACS Chemical Biology. 2646-2655.
  • Herfindal, Lars; Nygaard, Gyrid; Kopperud, Reidun Kristin; Krakstad, Camilla; Doskeland, Stein Ove; Selheim, Frode. 2013. Off-target effect of the Epac agonist 8-pCPT-2'-O-Me-cAMP on P2Y12 receptors in blood platelets. Biochemical and Biophysical Research Communications - BBRC. 603-608.
  • Myhren, Lene Elisabeth; Nygaard, Gyrid; Gausdal, Gro; Sletta, Håvard; Teigen, Knut; Degnes, Kristin Fløgstad; Zahlsen, Kolbjørn; Brunsvik, Anders; Bruserud, Øystein; Doskeland, Stein Ove; Selheim, Frode; Herfindal, Lars. 2013. Iodinin (1,6-dihydroxyphenazine 5,10-dioxide) from streptosporangium sp. induces apoptosis selectively in myeloid leukemia cell lines and patient cells. Marine Drugs. 332-349.
  • Herfindal, Lars; Myhren, Lene Elisabeth; Gjertsen, Bjørn Tore; Doskeland, Stein Ove; Gausdal, Gro. 2013. Functional p53 is required for rapid restoration of daunorubicin-induced lesions of the spleen. BMC Cancer.
  • Gausdal, Gro; Wergeland, Anita; Skavland, Jørn; Nguyen, Eric; Pendino, Frederic; ROUHEE, NAZANIN; McCormack, Emmet ; Herfindal, Lars; Kleppe, Rune; Havemann, Ursula; Schwede, Frank; Bruserud, Øystein; Gjertsen, Bjørn Tore; Lanotte, Michel; Ségal-Bendirdjian, Evelyne; Doskeland, Stein Ove. 2013. Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosis. Cell Death & Disease.
  • Oftedal, Linn Silje Wathne; Myhren, Lene Elisabeth; Jokela, Jouni; Gausdal, Gro; Sivonen, Kaarina; Doskeland, Stein Ove; Herfindal, Lars. 2012. The lipopeptide toxins Anabaenolysin A and B target biological membranes in a cholesterol-dependent manner. Biochimica et Biophysica Acta - Biomembranes. 3000-3009.
  • Jokela, Jouni; Oftedal, Linn Silje Wathne; Herfindal, Lars; Permi, Perttu; Wahlsten, Matti; Døskeland, Stein Ove; Sivonen, Kaarina. 2012. Anabaenolysins, novel cytolytic lipopeptides from benthic anabaena cyanobacteria. PLOS ONE.
  • Oftedal, Linn Silje Wathne; Skjærven, Kaja Helvik; Coyne, Rosie Theresa; Edvardsen, Bente; Rohrlack, Thomas; Skulberg, Olav; Doskeland, Stein Ove; Herfindal, Lars. 2011. The apoptosis-inducing activity towards leukemia and lymphoma cells in a cyanobacterial culture collection is not associated with mouse bioassay toxicity. Journal of Industrial Microbiology & Biotechnology. 489-501.
  • Herfindal, Lars; Myhren, Lene Elisabeth; Kleppe, Rune; Krakstad, Camilla; Selheim, Frode; Jokela, Jouni; Sivonen, Kaarina; Doskeland, Stein Ove. 2011. Nostocyclopeptide-M1: A potent, nontoxic inhibitor of the hepatocyte drug transporters OATP1B3 and 1B1. Molecular Pharmaceutics. 360-367.
  • Oftedal, Linn Silje Wathne; Selheim, Frode; Wahlsten, Matti; Sivonen, Kaarina; Doskeland, Stein Ove; Herfindal, Lars. 2010. Marine Benthic Cyanobacteria Contain Apoptosis-Inducing Activity Synergizing with Daunorubicin to Kill Leukemia Cells, but not Cardiomyocytes. Marine Drugs. 2659-2672.
  • Jokela, Jouni; Herfindal, Lars; Wahlsten, Matti; Permi, Perttu; Selheim, Frode; Vasconçelos, Vitor M.; Doskeland, Stein Ove; Sivonen, Kaarina. 2010. A novel cyanobacterial nostocyclopeptide is a potent antitoxin against microcystins. ChemBioChem. 1594-1599.
  • Prestegard, Siv Kristin; Oftedal, Linn Silje Wathne; Coyne, Rosie Theresa; Nygård, Gyrid; Skjærven, Kaja Helvik; Knutsen, Gjert; Doskeland, Stein Ove; Herfindal, Lars. 2009. Marine Benthic Diatoms Contain Compounds Able to Induce Leukemia Cell Death and Modulate Blood Platelet Activity. Marine Drugs. 605-623.
  • Jørgensen, Hanne; Degnes, Kristin; Sletta, Håvard; Fjærvik, Espen; Dikiy, Alexander; Herfindal, Lars; Bruheim, Per; Klinkenberg, Geir; Bredholt, Harald; Nygård, Gyrid; Doskeland, Stein Ove; Ellingsen, Trond E.; Zotchev, Sergey B. 2009. Biosynthesis of Macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit. Chemistry and Biology. 1109-1121.
  • Herfindal, Lars; Kasprzykowski, Franciszek; Schwede, Frank; Lankiewicz, Leszek; Fladmark, Kari Espolin; Lukomska, Joanna; Wahlsten, Matti; Sivonen, Kaarina; Grzonka, Zbigniew; Jastorff, Bernd; Doskeland, Stein Ove. 2009. Acyloxymethyl esterification of Nodularin-R and Microcystin-LA produces inactive protoxins that become reactivated and produce apoptosis inside intact cells. Journal of Medicinal Chemistry. 5758-5762.
  • Martins, Rosário F.; Ramos, Miguel F.; Herfindal, Lars; Sousa, José A. ; Skjærven, Kaja Helvik; Vasconcelos, Vitor M. 2008. Antimicrobial and cytotoxic assessment of marine cyanobacteria - Synechocystis and synechococcus. Marine Drugs. 1-11.
  • Krakstad, Camilla; Herfindal, Lars; Gjertsen, Bjørn Tore; Bøe, Roald; Vintermyr, Olav Karsten; Fladmark, Kari Espolin; Doskeland, Stein Ove. 2006. CaM-kinasell-dependent commitment to microcystin-induced apoptosis is coupled to cell budding, but not to shrinkage or chromatin hypercondensation. Cell Death and Differentiation. 1191-1202.
  • Selheim, Frode; Herfindal, Lars; Martins, Rosario; Vasconcelos, Vitor; Doskeland, Stein Ove. 2005. Neuro-apoptogenic and blood platelet targeting toxins in benthic marine cyanobacteria from the Portuguese coast. Aquatic Toxicology. 294-306.
  • Herfindal, Lars; Selheim, Frode; Oftedal, Linn Silje Wathne; Wahlsten, Matti; Sivonen, Kaarina; Doskeland, Stein Ove. 2005. A high proportion of Baltic Sea benthic cyanobacterial isolates contain apoptogens able to induce rapid death of isolated rat hepatocytes. Toxicon. 252-260.
  • Bruserud, Øystein; Glenjen, Nils; Gjertsen, Bjørn Tore; Herfindal, Lars; Døskeland, Stein Ove. 2002. Use of marine toxins in combination with cytotoxic drugs for induction of apoptosis in acute myelogenous leukaemia cells. Expert Opinion on Biological Therapy. 197-210.
  • Selheim, Frode; Herfindal, Lars; Knutsen, Gjert; Holmsen, Holm; Døskeland, Stein Ove. 2001. Alterations in platelet phospholipid metabolism by substances from a marine microalgae. Chemistry and Physics of Lipids. 139-140.
Report
  • Hagland, Hanne; Selheim, Frode; Keen, TJ; Skjærven, Kaja H; Christensen, Anne Elisabeth; Herfindal, Lars; Doskeland, Stein Ove. 2005. The cAMP Receptors Epac and PKA synergize to induce PC12 cell neuritogenesis and to protect against apoptosis. .
Academic lecture
  • Vu, Marita Hoang Anh; Herfindal, Lars; Juvik, Ole Johan; Vedeler, Anni; Haavik, Svein; Fossen, Torgils. 2017. Rome –en unik kilde til nye antileukemi naturprodukter.
  • Sæbø, Eirik Færøy; Storesund, Julia Endresen; Herfindal, Lars; Øvreås, Lise. 2017. Isolation and screening of novel planctomycetes from Svarthamar ice Cave, Northern Norway.
  • Herfindal, Lars. 2011. Bioactive compounds from culturable marine microorganisms.
  • Stensun, S.; Hatfield, Kimberley; Knutsen, Gjert; Erga, S.R.; Aursland, K.; Herfindal, Lars; Solheim, F.; Døskeland, S.O.; Urtegaard, A.; Gjetle, A.; Andersen, Knut-Jan. 2003. Drug potentials from marine cyanobacteria and microalgae from Norwegian waters.
  • Herfindal, Lars; Selheim, Frode; Knutsen, Gjert; Døskeland, Stein Ove. 2002. New apoptosis-modulating substances from marine microalgae.
  • Fladmark, Kari Espolin; Herfindal, Lars; Døskeland, Stein Ove; Knutsen, Gjert; Rivero, A; Eriksson, J.E.; Wahlsten, M; Sivonen, K; Valle, R; Vasconcelos, V; Webb, P; Lord, J; Schwede, F; Jastorff, B; Genieser, H.G.; Lankiewicz, L.; Kasprzykowski, F.; Graslund, A; Langel, U; Törnroos, Karl Wilhelm; Villa-Moruzzi, E. 2002. Bioactive compounds from cyanobacteria.
  • Herfindal, Lars; Tanaka, Masaru; Rønnestad, Ivar. 1999. Effect of feeding Artemia enriched with free phenylalanine and tyrosine to larval Japanese flounder.
Editorial
  • Selheim, Frode; Herfindal, Lars. 2016. Toward personalized treatment for acute myeloid leukemia. Current Pharmaceutical Biotechnology. 4-5.
  • Selheim, Frode; Herfindal, Lars. 2016. Editorial: Toward Personalized Treatment for Acute Myeloid Leukemia. Current Pharmaceutical Biotechnology. 4-5.
Short communication
  • Serkland, Trond T.; Schjøtt, Jan; Berg, Jon Andsnes; Herfindal, Lars; Riedel, Bettina; Skrede, Silje. 2019. Short communication: Distribution of psychotropic drugs into lipoproteins. Therapeutic Drug Monitoring. 766-771.
Masters thesis
  • Gundersen, Edvin Tang. 2016. The production and characterization of drug-loaded liposomal and PLGA nanocarriers for targeted treatment of acute myeloid leukemia.
  • Johannessen, Fredrik Gullaksen. 2016. The efficiency of maltodextrin and porous silicon nanoparticles for the in vitro and in vivo stabilization of tyrosine hydroxylase.
  • Furevik, Sarah Marie Vie. 2015. The role of Epac1 in endothelial barrier function Fluorescence intensity measurements of nano capsules in Wnt1-induced breast cancer.
  • Milankovic, Silje. 2012. In vivo biodistribution of fluorescent nanocolloids intended for drug delivery. Evaluation of PEGylation state and fluorophore incorporation approach.
  • Nilssen, Ida Mostrøm. 2012. In vitro validation of multifunctional liposomes for leukaemia and prostate cancer therapy ¿ the folate receptor and the prostate-specific membrane antigen as targets for drug delivery.
  • Larsen, Maria Helen Kurki. 2008. Platelet inhibitory compounds from marine microorganisms.
  • Nygård, Gyrid. 2008. Bioactive compounds from marine microorganisms: search for anti-leukemic drugs and finding mechanisms of action.
Popular scientific article
  • Herfindal, Lars; Nilssen, Ida Mostrøm; Milankovic, Silje. 2012. Nanokolloidar som verkty for å betra distribusjon av legemiddel. Naturen. 103-110.
  • Prestegard, Siv Kristin; Herfindal, Lars. 2004. Havet som apotek. Naturen. 15-24.
  • Tonheim, Sigurd; Herfindal, Lars; Rønnestad, I. 2000. Anrikning av vannløselige komponenter i Artemia. Norsk Fiskeoppdrett. 26-27.
Doctoral dissertation
  • Herfindal, Lars. 2006. Apoptosis modulating and anti-thrombotic activities from marine micro-organisms.
Interview
  • Oppegård, Guri Gunnes; Øvreås, Lise; Herfindal, Lars; Lauritzen, Stein-Erik. 2019. Mikrobejakten. Langt inne i en isgrotte i Nordland har forskerne lett ettr ny antibiotika. Det haster å hente ut ukjente bakteriestammer, for verdens minste organismer står if are for å smelte bort.
Academic chapter/article/Conference paper
  • Gausdal, Gro; Krakstad, Camilla; Herfindal, Lars; Doskeland, Stein Ove. 2007. Serine/Threonine Protein Phosphatases in Apoptosis. 16 pages.
Abstract
  • Myhren, Lene Elisabeth; Nilsen, IM; Nicolas, Valerie; Doskeland, Stein Ove; Barratt, Gillian; Herfindal, Lars. 2013. Development and in vitro efficacy of liposomes carrying anthracyclines and emetine for enhanced therapeutic effect. The FEBS Journal. 322-322.
  • Jokela, J; Matti, W; Herfindal, Lars; Fewer, D; Rouhiainen, L; Oksanen, I; Halinen, K; Sivonen, K. 2008. Bioactive peptides from cyanobacteria. Journal of Peptide Science. 93-93.
Poster
  • Viktorsson, Elvar Örn; Åstrand, Ove Alexander Høgmoen; Bonge-Hansen, Tore; Doskeland, Stein Ove; Herfindal, Lars; Rongved, Pål. 2016. Total synthesis and initial antileukemic evaluation of the phenazine 5,10-dioxide natural products iodinin and myxin.
  • Fouillet, Bruno; Nacereddine, Abdelhamid; Larsen, Nina Lied; Bouaziz, Zouhair; Herfindal, Lars; Marminon, Christelle; Bollacke, Andre; Doskeland, Stein Ove; Le Borgne, Marc. 2015. Indeno[1,2-b]indole derivatives as protein kinase CK2 inhibitors: comparison of in silico models for Tox prediction.
  • Herfindal, Lars; Myhren, Lene Elisabeth; Nilssen, Ida Mostrøm; Nicolas, Valerie; Doskeland, Stein Ove; Barratt, Gillian. 2012. Development and in vitro efficacy of liposomes carrying anthracyclines and emetine for enhanced therapeutic effect.
  • Perander, maria; Stiberg, Trine; Myhren, Lene Elisabeth; Hansen, Espen; Seternes, ole morten; Herfindal, Lars; Andersen, Jeanette hammer; Jørgensen, Trond Ø. 2011. Characterization of cytotoxic activities in extracts from two marine invertebrates.
  • Herfindal, Lars; Myhren, Lene Elisabeth; Kleppe, Rune; Krakstad, Camilla; Selheim, Frode; Doskeland, Stein Ove. 2010. Liver specific transporters of microcystins as a tool to find novel inhibitors of OATP1B1 and OATP1B3.
  • Jørgensen, Hanne; Degnes, Kristin F.; Sletta, Håvard; Fjærvik, Espen; Dikiy, Alexander; Herfindal, Lars; Bruheim, Per; Klinkenberg, Geir; Bredholt, Harald; Nygård, Gyrid; Døskeland, Stein O.; Ellingsen, Trond Erling; Zotchev, Sergey. 2009. The biosynthesis of macrolactam BE-14106: a new way of generating an aminoacyl starter unit.
  • Prestegard, S; Hatfield, Kimberley Joanne; Knutsen, G.; Erga, Svein Rune; Aursland, Kjetil; Herfindal, Lars; Selheim, Frode; Døskeland, S.O.; Urtegaard, Asta Sande; Andersen, Knut-Jan. 2005. Searching cyanobacteria and microalgae from Norwegian waters for drug candidates.
  • Herfindal, Lars; Selheim, Frode; Aursland, Kjetil; Krakstad, Camilla; Knutsen, Gjert; Døskeland, Stein Ove. 2002. Effects of a new bioactive substance from a marine microalga on mammalian cells.
  • Herfindal, Lars; Krakstad, Camilla; Selheim, Frode; Wahlsten, Matti; Knutsen, Gjert; Sivonen, Kaarina; Døskeland, Stein Ove. 2001. TWO NOVEL APOPTOSIS-MODULATION SUBSTANCES ISOLATED FROM MARINE MICRO-ALGAE.
  • Herfindal, Lars; Selheim, Frode; Knutsen, Gjert; Døskeland, Stein Ove. 2001. New apoptosis-modulating substances from marine microalgae.
Academic literature review
  • Singh, Aditi; Myklebust, Nikolai Norevik; Furevik, Sarah Marie Vie; Haugse, Ragnhild; Herfindal, Lars. 2019. Immunoliposomes in acute myeloid leukaemia therapy. An overview of possible targets and obstacles. 5278-5292.
  • Sauvage, Félix; Barratt, Gillian; Herfindal, Lars; Vergnaud-Gauduchon, Juliette. 2016. The use of nanocarriers in acute myeloid leukaemia therapy: Challenges and current status. 30-41.
  • Kleppe, Rune; Herfindal, Lars; Doskeland, Stein Ove. 2015. Cell Death inducing microbial protein phosphatase inhibitors-mechanisms of action. 6505-6520.
  • Herfindal, Lars; Selheim, Frode. 2006. Microcystin produces disparate effects on liver cells in a dose dependent manner. 279-285.

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