- E-maillilah.toker@uib.no
- Phone+47 413 79 266
- Visitor AddressHaukeland Universitetssykehus Laboratoriebygget, 7. etg. Heis øst5009 Bergen
- Postal AddressPostboks 78045020 Bergen
Academic article
- (2022). A nationwide study of the incidence, prevalence and mortality of Parkinson’s disease in the Norwegian population. NPJ Parkinson's Disease. 1-8.
- (2021). Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson’s disease brain. Molecular Neurodegeneration. 1-20.
- (2020). Common gene expression signatures in Parkinson’s disease are driven by changes in cell composition. Acta neuropathologica communications. 1-14.
Letter to the editor
- (2021). BMP5/7 protect dopaminergic neurons in an α-synuclein mouse model of Parkinson's disease. Brain.
More information in national current research information system (CRIStin)
- Toker L., Tran GT., Sundaresan J., Tysnes OB., Alves G., Haugarvoll K., Nido G., Dölle C., Tzoulis C. Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson's disease brain. (In press, Molecular Neurodegeneration)
- Vitic Z., Safory H., Jovanovic V.M., Sarusi Y., Stavsky A., Kahn J., Kuzmina A., Toker L., Gitler D., Taube R., Friedel R.H., Engelender S., Brodski C. BMP5/7 protect dopaminergic neurons in an α -synuclein mouse model of Parkinson’s disease. Brain, 2020.
- Beasley C., Toker L., Hercher C., Shao L. Decreased density of activated microglia and lower anti-inflammatory cytokine expression in frontal cortex in bipolar disorder. Bipolar Disorders, 2020
- Nido G., Dick F., Toker L., Petersen K., Alves G., Tysnes OB., Jonassen I., Haugarvoll K., Tzoulis C. Common gene expression signatures in Parkinson’s disease are driven by changes in cell composition. Acta Neuropathol Commun. 2020
- Zhuang B., Mancarci BO., Toker L., Pavlidis P. Mega-analysis of gene expression in mouse models of Alzheimer’s disease. Eneuro, 2019
- L., Mancarci B. O., Tripathy S., Pavlidis P. Transcriptomic evidence for alterations in astrocytes and parvalbumin interneurons in bipolar disorder and schizophrenia subjects. Biological Psychiatry, 2018
- Tripathy S.,Toker L., Bomkamp C., Mancarci B.O., Belmadani M., Pavlidis P. Assessing Transcriptome Quality in Patch-Seq Datasets. Front Mol Neurosci,. 2018
- Damri O., Agam G., Toker L.* The observed alteration in BCL2 expression following lithium treatment is influenced by the choice of normalization method. Scientific Reports, 2018
- Mancarci B. O., Toker L., Tripathy S., Li B., Rocco B., Sibille E., Pavlidis P. Cross-Laboratory analysis of brain cell type transcriptomes with applications to interpretation of bulk tissue data. eNeuro, 2017
- Tripathy S., Toker L., Li B., Crichlow C., Tebaykin D., Mancarci B. O., Pavlidis P. Transcriptomic correlates of neuron electrophysiological diversity PLOS Computational Biology, 2017
- Agam G., Toker L., Sade Y., Damri O. The possible interaction between mitochondrial function and autophagy in the mechanism of mood stabilization. Bipolar Disorders, 2017
- Toker L., Feng M., Pavlidis P. Whose sample is it anyway? Widespread misannotation of samples in transcriptomics studies. F1000Research, 2016
Horvath G., Demos M., Shyr C., Matthews A., Zhang L., Race S., Stockler-Ipsiroglu S., Van Allen MI., Mancarci O., Toker L., Pavlidis P., Ross CJ., Wasserman WW., Trump N., Heales S., Pope S., Cross H., Van Karnebeek CDM.Secondary neurotransmitter deficiencies in epilepsy caused by voltage-gated sodium channelopathies: a potential treatment target? Molecular Genetics and Metabolism, 2016
- Sade Y., Toker L., Kara NZ., Einat H., Rapoport S., Moechars D., Berry GT., Bersudsky Y,Agam G. IP3 accumulation and/or inositol depletion: two downstream lithium’s effects that may mediate its behavioral and cellular changes. Translational Psychiatry, 2016
- Toker L., Pavlidis P. Metaanalysis of flawed expression profiling data leading to erroneous Parkinson’s biomarker identification. PNAS, 2015
- Toker L., Agam G. Mitochondrial dysfunction in psychiatric morbidity: current evidence and therapeutic prospects. Neuropsychiatric disease and treatment.2015
- Toker L., Bersudsky Y., Planchkes I., Chalifa-Caspi V., Berry TG., Buccafusca R., Moehares D., Belmaker RH., Agam G. Inositol-related gene knockouts mimic lithium’s effect on mitochondrial function. Neuropsychopharmacology, 2014
- Toker L., Agam G. Lithium, inositol and mitochondria. ACS chemical neuroscience. 2014
- Sade Y., Kara NZ., Toker L., Bersudsy Y., Einat H., Agam G. Beware of your mouse strain; differential effects of lithium on behavioral and neurochemical phenotypes in Harlan ICR mice bred in Israel or the USA. Pharmacology Biochemistry and Behaviour, 2014
- Kara NZ*, Toker L*., Agam G., Belmaker RH, Einat H. Trehalose induced antidepressant-like effects and autophagy enhancement in mice. Psychopharmacology, 2013
- Toker L., Belmaker RH, Agam G. Gene-expression studies in understanding the mechanism of action of lithium. Expert review of neurotherapeutics, 2012
Fields of competence