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University of Bergen
Lilah Toker's picture

Lilah Toker

Researcher, Senior researcher
Department of Clinical Medicine
  • E-mailLilah.Toker@uib.no
  • Phone+47 413 79 266
  • Visitor Address
    Haukeland Universitetssykehus Laboratoriebygget, 7. etg. Heis øst
    5009 Bergen
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • Show author(s) (2022). A nationwide study of the incidence, prevalence and mortality of Parkinson’s disease in the Norwegian population. NPJ Parkinson's Disease. 1-8.
  • Show author(s) (2021). Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson’s disease brain. Molecular Neurodegeneration. 1-20.
  • Show author(s) (2020). Common gene expression signatures in Parkinson’s disease are driven by changes in cell composition. Acta neuropathologica communications. 1-14.
Letter to the editor
  • Show author(s) (2021). BMP5/7 protect dopaminergic neurons in an α-synuclein mouse model of Parkinson's disease. Brain.

More information in national current research information system (CRIStin)

  1. Toker L., Tran GT., Sundaresan J., Tysnes OB., Alves G., Haugarvoll K., Nido G., Dölle C., Tzoulis C. Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson's disease brain. (In press, Molecular Neurodegeneration)
  2. Vitic Z., Safory H., Jovanovic V.M., Sarusi Y., Stavsky A., Kahn J., Kuzmina A., Toker L., Gitler D., Taube R., Friedel R.H., Engelender S., Brodski C. BMP5/7 protect dopaminergic neurons in an α -synuclein mouse model of Parkinson’s disease. Brain, 2020.
  3. Beasley C., Toker L., Hercher C., Shao L. Decreased density of activated microglia and lower anti-inflammatory cytokine expression in frontal cortex in bipolar disorder. Bipolar Disorders, 2020
  4. Nido G., Dick F., Toker L., Petersen K., Alves G., Tysnes OB., Jonassen I., Haugarvoll K., Tzoulis C. Common gene expression signatures in Parkinson’s disease are driven by changes in cell composition. Acta Neuropathol Commun. 2020
  5. Zhuang B., Mancarci BO., Toker L., Pavlidis P. Mega-analysis of gene expression in mouse models of Alzheimer’s disease. Eneuro, 2019
  6. L., Mancarci B. O., Tripathy S., Pavlidis P. Transcriptomic evidence for alterations in astrocytes and parvalbumin interneurons in bipolar disorder and schizophrenia subjects. Biological Psychiatry, 2018
  7. Tripathy S.,Toker L., Bomkamp C., Mancarci B.O., Belmadani M., Pavlidis P. Assessing Transcriptome Quality in Patch-Seq Datasets. Front Mol Neurosci,. 2018
  8. Damri O., Agam G., Toker L.* The observed alteration in BCL2 expression following lithium treatment is influenced by the choice of normalization method. Scientific Reports, 2018
  9. Mancarci B. O., Toker L., Tripathy S., Li B., Rocco B., Sibille E., Pavlidis P. Cross-Laboratory analysis of brain cell type transcriptomes with applications to interpretation of bulk tissue data. eNeuro, 2017
  10. Tripathy S., Toker L., Li B., Crichlow C., Tebaykin D., Mancarci B. O., Pavlidis P. Transcriptomic correlates of neuron electrophysiological diversity PLOS Computational Biology, 2017  
  11. Agam G., Toker L., Sade Y., Damri O. The possible interaction between mitochondrial function and autophagy in the mechanism of mood stabilization. Bipolar Disorders, 2017
  12. Toker L., Feng M., Pavlidis P. Whose sample is it anyway? Widespread misannotation of samples in transcriptomics studies. F1000Research, 2016

  13. Horvath G., Demos M., Shyr C., Matthews A., Zhang L., Race S., Stockler-Ipsiroglu S., Van Allen MI., Mancarci O., Toker L., Pavlidis P., Ross CJ., Wasserman WW., Trump N., Heales S., Pope S., Cross H., Van Karnebeek CDM.Secondary neurotransmitter deficiencies in epilepsy caused by voltage-gated sodium channelopathies: a potential treatment target? Molecular Genetics and Metabolism, 2016

  14. Sade Y., Toker L., Kara NZ., Einat H., Rapoport S., Moechars D., Berry GT., Bersudsky Y,Agam G. IP3 accumulation and/or inositol depletion: two downstream lithium’s effects that may mediate its behavioral and cellular changes. Translational Psychiatry, 2016
  15. Toker L., Pavlidis P. Metaanalysis of flawed expression profiling data leading to erroneous Parkinson’s biomarker identification. PNAS, 2015
  16. Toker L., Agam G. Mitochondrial dysfunction in psychiatric morbidity: current evidence and therapeutic prospects. Neuropsychiatric disease and treatment.2015
  17. Toker L., Bersudsky Y., Planchkes I., Chalifa-Caspi V., Berry TG., Buccafusca R., Moehares D., Belmaker RH., Agam G. Inositol-related gene knockouts mimic lithium’s effect on mitochondrial function. Neuropsychopharmacology, 2014
  18. Toker L., Agam G. Lithium, inositol and mitochondria. ACS chemical neuroscience. 2014
  19. Sade Y., Kara NZ., Toker L., Bersudsy Y., Einat H., Agam G. Beware of your mouse strain; differential effects of lithium on behavioral and neurochemical phenotypes in Harlan ICR mice bred in Israel or the USA. Pharmacology Biochemistry and Behaviour, 2014
  20. Kara NZ*, Toker L*., Agam G., Belmaker RH, Einat H. Trehalose induced antidepressant-like effects and autophagy enhancement in mice. Psychopharmacology, 2013
  21. Toker L., Belmaker RH, Agam G. Gene-expression studies in understanding the mechanism of action of lithium. Expert review of neurotherapeutics, 2012
Fields of competence 
Animal models
Biochemistry
Bioinformatics
Data Analysis
Parkinson's disease