Home
Linda Elin Birkhaug Stuhr's picture

Linda Elin Birkhaug Stuhr

Professor
  • E-mailLinda.Stuhr@uib.no
  • Phone+47 55 58 63 86+47 55 58 63 93
  • Visitor Address
    Jonas Lies vei 91
    Room 
    7A109Y
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • Smeland, Hilde Ytre-Hauge; Lu, Ning; Karlsen, Tine Veronica; Salvesen, Gerd Signe; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug. 2019. Stromal integrin α11-deficiency reduces interstitial fluid pressure and perturbs collagen structure in triple-negative breast xenograft tumors. BMC Cancer. 1-13.
  • Primac, Irina; Maquoi, Erik; Blacher, Silvia; Heljasvaara, Ritva Leena; Van Deun, Jan; Smeland, Hilde Ytre-Hauge; Canale, Annalisa; Louis, Thomas A.; Stuhr, Linda Elin Birkhaug; Sounni, Nor Eddine; Cataldo, Didier; Pihlajaniemi, Taina; Pequeux, Christel; De Wever, Olivier; Gullberg, Donald; Noel, Agnes. 2019. Stromal integrin α11 regulates PDGFR-β signaling and promotes breast cancer progression. Journal of Clinical Investigation. 4609-4628.
  • Tveitarås, Maria Kathrine; Selheim, Frode; Sortland, Kristina; Salvesen, Gerd Signe; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug. 2019. Protein expression profiling of plasma and lungs at different stages of metastatic development in a human triple negative breast cancer xenograft model. PLOS ONE.
  • Smeland, Hilde Ytre-Hauge; Askeland, Cecilie; Wik, Elisabeth; Knutsvik, Gøril; Molven, Anders; Edelmann, Reidunn Jetne; Reed, Rolf K.; Warren, David; Gullberg, Donald; Stuhr, Linda Elin Birkhaug; Akslen, Lars A. 2019. Integrin α11β1 is expressed in breast cancer stroma and associates with aggressive tumor phenotypes. The journal of pathology. Clinical research. 69-82.
  • Tveitarås, Maria Kathrine; Reigstad, Inga; Leiss, Lina Wik; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug. 2017. Single factors alone can induce mesenchymal-like morphology, but not promote full EMT in breast cancer cell lines with different hormone statuses. Experimental Cell Research. 257-265.
  • Sletta, Kristine Yttersian; Tveitarås, Maria Kathrine; Lu, Ning; Svendsen, Agnete; Reed, Rolf K.; Garmann-Johnsen, Annette; Stuhr, Linda Elin Birkhaug. 2017. Oxygen-dependent regulation of tumor growth and metastasis in human breast cancer xenografts. PLOS ONE. 1-19.
  • Burmakin, Mikhail; van Wieringen, Tijs; Olsson, Olof; Stuhr, Linda Elin Birkhaug; Åhgren, Aive; Heldin, Carl-Henrik; Reed, Rolf K.; Rubin, Kristofer; Hellberg, Carina. 2017. Imatinib increases oxygen delivery in extracellular matrix-rich but not in matrix-poor experimental carcinoma. Journal of Translational Medicine.
  • Sønstevold, Tonje; Johannessen, Anne Christine; Reed, Rolf K.; Salvesen, Gerd Signe; Stuhr, Linda Elin Birkhaug. 2017. Hyperbaric oxygen treatment did not significantly affect radiation injury in the mandibular area of rats. Oral surgery, oral medicine, oral pathology and oral radiology. 112-119.
  • Bjørkum, Alvhild Alette; Oveland, Eystein; Stuhr, Linda Elin Birkhaug; Havnes, Marianne Bjordal; Berven, Frode; Grønning, Marit; Hope, Arvid. 2017. Fast hyperbaric decompression after heliox saturation altered the brain proteome in rats. PLOS ONE. 1-16.
  • Reigstad, Inga; Sortland, Kristina; Skogstrand, Trude; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug. 2016. The effect of stromal integrin β3-deficiency on two different tumors in mice. Cancers.
  • Reigstad, Inga; Smeland, Hilde Ytre-Hauge; Skogstrand, Trude; Sortland, Kristina; Schmid, Caroline; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug. 2016. Stromal integrin α11β1 affects RM11 prostate and 4T1 breast xenograft tumors differently. PLOS ONE.
  • Hope, Arvid; Stuhr, Linda Elin Birkhaug; Pavlin, Tina; Bjørkum, Alvhild Alette; Grønning, Marit. 2015. MRI of the central nervous system in rats following heliox saturation decompression. Undersea & Hyperbaric Medicine. 57-64.
  • Fack, Fred; Espedal, Heidi; Keunen, Olivier; Golebiewska, Anna; Obad, Nina; Harter, Patrick N.; Mittelbronn, Michel; Bähr, Oliver; Weyerbrock, Astrid; Stuhr, Linda Elin Birkhaug; Miletic, Hrvoje; Sakariassen, Per Øystein; Stieber, Daniel; Brekke, Cecilie; Lund-Johansen, Morten; Zheng, Liang; Gottlieb, Eyal; Niclou, Simone; Bjerkvig, Rolf. 2015. Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas. Acta Neuropathologica. 115-131.
  • Sønstevold, Tonje; Johannessen, Anne Christine; Stuhr, Linda Elin Birkhaug. 2015. A rat model of radiation injury in the mandibular area. Radiation Oncology.
  • Friman, Tomas; Gustafsson, Renata; Stuhr, Linda Elin Birkhaug; Chidiac, Jean; Heldin, Nils-Erik; Reed, Rolf K.; Oldberg, Åke; Rubin, Kristofer. 2012. Increased fibrosis and interstitial fluid pressure in two different types of syngeneic murine carcinoma grown in integrin beta 3-subunit deficient mice. PLOS ONE. 10 pages.
  • Moen, Ingrid; Jevne, Alison Charlotte; Wang, Jian; Kalland, Karl-Henning; Chekenya, Martha; Akslen, Lars A.; Sleire, Linda; Enger, Per Øyvind; Reed, Rolf K.; Øyan, Anne Margrete; Stuhr, Linda Elin Birkhaug. 2012. Gene expression in tumor cells and stroma in dsRed 4T1 tumors in eGFP-expressing mice with and without enhanced oxygenation. BMC Cancer. 10 pages.
  • Keunen, Olivier; Johansson, Mikael; Oudin, Anaîs; Sanzey, Morgane; Rahim, Siti A. Abdul; Fack, Fred; Thorsen, Frits Alan; Taxt, Torfinn; Bartos, Michael; Jirík, Radovan; Miletic, Hrvoje; Wang, Jian; Stieber, Daniel; Stuhr, Linda Elin Birkhaug; Moen, Ingrid; Brekke, Cecilie; Bjerkvig, Rolf; Niclou, Simone P. 2011. Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 3749-3754.
  • Moen, Ingrid; Salvesen, Gerd Signe; Reed, Rolf K.; Jevne, Alison Charlotte; Stuhr, Linda Elin Birkhaug. 2011. A reduction in the interstitial fluid pressure per se, does not enhance the uptake of the small molecular weight compound 5-fluoroacil into 4T1 mammary tumours. Drugs and Theapy Studies.
  • Moen, Ingrid; Øyan, Anne Margrete; Kalland, Karl-Henning; Tronstad, Karl Johan; Akslen, Lars A.; Chekenya, Martha; Sakariassen, Per Øystein; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug. 2009. Hyperoxic treatment induces mesenchymal to epithelial transition in a rat adenocarcinoma model. PLOS ONE.
  • Moen, Ingrid; Tronstad, Karl Johan; Kolmannskog, Odd; Salvesen, Gerd Signe; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug. 2009. Hyperoxia increases the uptake of 5-FU in mammary tumors independently of cganges in interstitial pressure and tumor stroma. BMC Cancer.
  • Klosowska-Wardegata, Agnieska; Hasumi, Yoko; Burmakin, Mikhail; Åhgren, Aive; Stuhr, Linda Elin Birkhaug; Moen, Ingrid; Reed, Rolf K.; Rubin, Kristofer; Hellberg, Carina; Heldin, Carl-Henrik. 2009. Combined anti-angiogenic therapy targeting PDGF- and VEGF reseptors lowered the interstitial fluid pressure in a murine experimental carcinoma. PLOS ONE.
  • Skogland, Steffen; Stuhr, Linda Elin Birkhaug; Sundland, Harald; Olsen, Roy Edgar; Hope, Arvid. 2008. Venous gas emboli in normal and dehydrated rats following decompression from a saturation dive. Aviation, Space and Environmental Medicine. 565-569.
  • Stuhr, Linda Elin Birkhaug; Moen, Ingrid; Nedrebø, Torbjørn; Salnikov, Alexei; Wiig, Helge; Rubin, Kristofer; Reed, Rolf K. 2008. Peritumoral TNFalpha administration influences tumor stroma structure and physiology independently of growth in DMBA-induced mammary tumours. Scandinavian Journal of Clinical and Laboratory Investigation. 602-611.
  • Stuhr, Linda Elin Birkhaug; Moen, Ingrid; Nedrebø, Torbjørn; Salnikov, Alexei; Wiig, Helge; Rubin, Kristofer; Reed, Rolf K. 2008. Peritumoral TNF alpha administration influences tumour stroma structure and physiology independently of growth in DMBA-induced mammary tumours. Scandinavian Journal of Clinical and Laboratory Investigation. 602-611.
  • Wang, Jian; Sakariassen, Per Øystein; Tsinkalovsky, Oleg; Immervoll, Heike; Bøe, Stig Ove; Svendsen, Agnete; Prestegarden, Lars; Røsland, Gro Vatne; Thorsen, Frits Alan; Stuhr, Linda Elin Birkhaug; Molven, Anders; Bjerkvig, Rolf; Enger, Per Øyvind. 2008. CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. International Journal of Cancer. 761-768.
  • Stuhr, Linda Elin Birkhaug; Raa, Anette Bjaaland; Øyan, Anne Margrete; Kalland, Karl-Henning; Sakariassen, Per Øystein; Petersen, Kjell; Bjerkvig, Rolf; Reed, Rolf Kåre. 2007. Hyperoxia retards growth and induces apoptosis, changes in vascular density and gene expression in transplanted gliomas in nude rats. Journal of Neuro-Oncology. 191-202.
  • Raa, Anette Bjaaland; Stansberg, Christine; Steen, Vidar Martin; Bjerkvig, Rolf; Reed, Rolf Kåre; Stuhr, Linda Elin Birkhaug. 2007. Hyperoxia retards growth and induces apoptosis and loss of glands and blood vessels in DMBA-induced rat mammary tumors. BMC Cancer. 10 pages.
  • Oldberg, Å; Kalamajski, S; Sainikov, AV; Stuhr, Linda Elin Birkhaug; Morgelin, M; Reed, Rolf Kåre; Heldin, Nils-Erik; Rubin, Kristofer. 2007. Collagen-binding proteoglycan fibromodulin can determine stroma matrix structure and fluid balance in experimental carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 13966-13971.
  • Thorsen, Einar; Segadal, Kåre; Stuhr, Linda Elin Birkhaug; Troland, Kari; Grønning, M.; Marstein, Sverre; Hope, Arvid. 2006. No changes in lung function after a saturation dive to 2.5 MPa with intermittent reduction in Po-2 during decompression. European Journal of Applied Physiology. 270-275.
  • Salnikov, Alexei V.; Heldin, Nils-Erik; Stuhr, Linda Elin Birkhaug; Wiig, Helge; Gerber, Hanspeter; Reed, Rolf Kåre; Rubin, Kristofer. 2006. Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma. International Journal of Cancer. 2795-2802.
  • Stuhr, Linda Elin Birkhaug; Salnikov, Andrej V.; Iversen, Vegard Vereide; Salvesen, Gerd Signe; Rubin, Kristofer; Reed, Rolf Kåre. 2006. High-dose, short-term, anti-inflammatory treatment with dexamethasone reduces growth and augments the effects of 5-fluorouracil on dimethyl-alpha- benzanthracene-induced mammary tumors in rats. Scandinavian Journal of Clinical and Laboratory Investigation. 477-486.
  • Stuhr, Linda Elin Birkhaug; Iversen, Vegard Vereide; Straume, Oddbjørn; Mæhle, Bjørn Ove; Reed, Rolf Kåre. 2004. Hyperbaric oxygen alone or combined with 5-FU attenuates growth of DMBA-induced rat mammary tumors. Cancer Letters. 35-40.
  • Stuhr, Linda Elin Birkhaug; Mæhle, Bjørn Ove. 1997. The effect of Losartan, an angiotensin II antagonist, on cardiac function, mass and morphology in rats after repeated hyperbaric exposures. Scandinavian Journal of Clinical and Laboratory Investigation. 253-262.
Report
  • Stuhr, Linda Elin Birkhaug. 1995. Hvordan påvirkes sirkulasjon av trykk og oksygen. .
Popular scientific lecture
  • Stuhr, Linda Elin Birkhaug. 1993. Effekter av simulerte dykk på hjertefunksjonen.
Non-fiction book
  • Dalgaard, I.; Kleinert, P.; Stuhr, Linda Elin Birkhaug. 1994. Øje for øje : en antologi om synet. Det Kongelige Danske Kunstakademi.
Masters thesis
  • Brodahl, Tore-Andre. 2018. The in vivo effect of integrin α11-deficiency and PDGFR inhibition in breast cancer.
  • Sletta, Kristine Yttersian. 2016. The effect of hyperbaric oxygen treatment on malignant progression in different breast cancer models in vivo.
  • Sortland, Kristina. 2014. THE EFFECT OF INTEGRIN β3-DEFICIENCY ON 4T1 MAMMARY TUMORS IN MICE.
  • Sønstevold, Tonje. 2014. Model for Late Radiation Tissue Injury.
  • Halvorsen, Mariel Baustad. 2013. Physical activity and cardiovascular health in the elderly population.
  • Garmann-Johnsen, Annette. 2012. The effect of hyperbaric oxygen treatment, alone or in combination with 5-FU, on a MDA-MB-231 human mammary tumor model.
  • Jevne, Alison Charlotte. 2010. AN eGFP-EXPRESSING IMMUNODEFICIENT MOUSE MODEL WITH dsRED TRANSFECTED MAMMARY TUMOURS, AND THE EFFECT OF HYPERBARIC OXYGEN TREATMENT.
  • Monsen, Agnete. 2008. Simplified detection of dynamic hyperinflation in patients with chronic obstructive pulmonary disease. Validity and reproducibility in a clinic relevant context.
  • Moen, Ingrid. 2007. The effect of hyperbaric oxygen on the tumor interstitium; physiology and structure. A study on DMBA-induced mammary tumors in rats.
Popular scientific article
  • Stuhr, Linda Elin Birkhaug. 1995. Effekten av simulerte dykk på hjertets funksjon og morfologi. Insicura. 27-28.
Doctoral dissertation
  • Reigstad, Inga. 2017. Investigation of different aspects of the tumor microenvironment as determinants of tumor development and progression.
  • Stuhr, Linda Elin Birkhaug. 1993. Cardiovascular changes during moderate hyperbaric exposures. Effect of acute, and repeated hyperbaric exposure, and pharmacological interventions on cardiac functions. (cand.philos).
Poster
  • Moen, Ingrid; Øyan, Anne Margrete; Kalland, Karl-Henning; Tronstad, Karl Johan; Akslen, Lars A.; Chekenya, Martha; Sakariassen, Per Øystein; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug. 2009. Hyperoxic Treatment induces Mesenchymal-to-Epithelial Transition in a Rat Adenocarcinoma Model.
Academic literature review
  • Stuhr, Linda Elin Birkhaug; Wei, Eddie T.; Reed, Rolf K. 2014. Corticotropin-releasing factor reduces tumor volume, halts further growth, and enhances the effect of chemotherapy in 4T1 mammary carcinoma in mice. 1365-1370.
  • Moen, Ingrid; Stuhr, Linda Elin Birkhaug. 2012. Hyperbaric oxygen therapy and cancer-a review. 233-242.

More information in national current research information system (CRIStin)