Home
Marit Bakke's picture

Marit Bakke

Professor, Vice Dean of Research, Faculty of Medicine
  • E-mailMarit.Bakke@uib.no
  • Phone+47 55 58 60 14+47 958 18 531
  • Visitor Address
    Armauer Hansens Hus
    Haukelandsveien 28
    Room 
    410, 4th floor
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • Åsrud, Kathrine Sivertsen; Pedersen, Line; Aesoy, Reidun; Muwonge, Haruna; Aasebø, Elise; Pettersen, Ina Katrine Nitschke; Herfindal, Lars; Dobie, Ross; Jenkins, Stephen; Berge, Rolf Kristian; Henderson, Neil Cowan; Selheim, Frode; Doskeland, Stein Ove; Bakke, Marit. 2019. Mice depleted for Exchange Proteins Directly Activated by cAMP (Epac) exhibit irregular liver regeneration in response to partial hepatectomy. Scientific Reports. 1-17.
  • Gucek, Alenka; Gandasi, Nikhil R.; Omar-Hmeadi, Muhmmad; Bakke, Marit; Doskeland, Stein Ove; Tengholm, Anders; Barg, Sebastian. 2019. Fusion pore regulation by cAMP/Epac2 controls cargo release during insulin exocytosis . eLIFE.
  • Aesoy, Reidun; Muwonge, Haruna; Sivertsen Åsrud, Kathrine; Sabir, Misbah; Witsø, Solveig Lund; Bjørnstad, Ronja; Kopperud, Reidun Kristin; Høivik, Erling Andre; Doskeland, Stein Ove; Bakke, Marit. 2018. Deletion of exchange proteins directly activated by cAMP (Epac) causes defects in hippocampal signaling in female mice. PLOS ONE.
  • Kopperud, Reidun Kristin; Rygh, Cecilie Brekke; Karlsen, Tine Veronica; Krakstad, Camilla; Kleppe, Rune; Høivik, Erling Andre; Bakke, Marit; Tenstad, Olav; Selheim, Frode; Liden, Åsa; Madsen, Lise; Pavlin, Tina; Taxt, Torfinn; kristiansen, k; Curry, FE; Reed, Rolf K.; Doskeland, Stein Ove. 2017. Increased microvascular permeability in mice lacking Epac1 (Rapgef3). Acta Physiologica. 441-452.
  • Nygaard, Gyrid; Herfindal, Lars; Sivertsen Åsrud, Kathrine; Bjørnstad, Ronja; Kopperud, Reidun Kristin; Oveland, Eystein; Berven, Frode; Myhren, Lene Elisabeth; Høivik, Erling Andre; Lunde, Turid Helen Felli; Bakke, Marit; Doskeland, Stein Ove; Selheim, Frode. 2017. Epac1-deficient mice have bleeding phenotype and thrombocytes with decreased GPIbβ expression. Scientific Reports. 1-15.
  • Lewis, Aurelia Eva; Aesoy, Reidun; Bakke, Marit. 2016. Role of EPAC in cAMP-mediated actions in adrenocortical cells. Frontiers in Endocrinology. 7 pages.
  • Edland, Ravn Fritdtjov; Wergeland, Anita; Kopperud, Reidun Kristin; Sivertsen åsrud, Kathrine; Høivik, Erling Andre; Witsø, Solveig Lund; Æsøy, Reidun; Madsen, Lise; Kristiansen, K; Bakke, Marit; Doskeland, Stein Ove; Jonassen, Anne K. 2016. Long-term consumption of an obesogenic high fat diet prior to ischemia-reperfusion mediates cardioprotection via Epac1-dependent signaling. Nutrition & Metabolism. 1-11.
  • Edvardsen, Kine Susann Waade; Bjånesøy, Trine Elholm; Hellesen, Alexander; Breivik, Lars Ertesvåg; Bakke, Marit; Husebye, Eystein Sverre; Bratland, Eirik. 2015. Peripheral blood cells from patients with autoimmune Addison's disease poorly respond to interferons in vitro, despite elevated serum levels of interferon-inducible chemokines. Journal of Interferon and Cytokine Research. 759-770.
  • Æsøy, Reidun; Gradin, Katarina; Åsrud, Kathrine Sivertsen; Høivik, Erling Andre; Ruas, Jorge Lira; Poellinger, Lorenz; Bakke, Marit. 2014. Regulation of CDKN2B expression by interaction of Arnt with Miz-1 - a basis for functional integration between the HIF and Myc gene regulatory pathways. Molecular Cancer.
  • Sharma, Yogita; Chilamakuri, Chandra Sekhar Reddy; Bakke, Marit; Lenhard, Boris. 2014. Computational characterization of modes of transcriptional regulation of nuclear receptor genes. PLOS ONE.
  • Bjånesøy, Trine Elholm; Kulle, Bettina; Bratland, Eirik; Reiner, Andrew Henry; Islam, Shahinul; Husebye, Eystein Sverre; Bakke, Marit. 2014. Altered DNA methylation profile in Norwegian patients with Autoimmune Addison's Disease. Molecular Immunology. 208-216.
  • Høivik, Erling Andre; Witsø, Solveig Lund; Bergheim, Inger Riise; Xu, Yunjian; Jakobsson, Ida; Tengholm, Anders; Doskeland, Stein Ove; Bakke, Marit. 2013. DNA methylation of alternative promoters directs tissue specific expression of Epac2 isoforms. PLOS ONE. 12 pages.
  • Høivik, Erling Andre; Bjånesøy, Trine Elholm; Mai, Oliver; Okamoto, Shiki; Minokoshi, Yasuhiko; Shima, Yuichi; Morohashi, Ken-Ichirou; Boehm, Ulrich; Bakke, Marit. 2011. DNA methylation of intronic enhancers directs tissue- specific expression of steroidogenic factor 1/adrenal 4 binding protein (SF-1/Ad4BP). Endocrinology. 2100-2112.
  • Aumo, Linda; Rusten, Marte; Mellgren, Gunnar; Bakke, Marit; Lewis, Aurelia. 2010. Functional roles of protein kinase A (PKA) and exchange protein directly activated by 3',5'-cyclic adenosine 5'-monophosphate (cAMP) 2 (EPAC2) in cAMP-mediated actions in adrenocortical cells. Endocrinology. 2151-2161.
  • Lewis, Aurelia; Rusten, Marte; Høivik, Erling Andre; Vikse, Elisabeth Lea; Hansson, Magnus L.; Wallberg, Annika E.; Bakke, Marit. 2008. Phosphorylation of steroidogenic factor 1 is mediated by cyclin-dependent kinase 7. Molecular Endocrinology. 91-104.
  • Høivik, Erling Andre; Aumo, Linda; Æsøy, Reidun; Lillefosse, Haldis Haukås; Lewis, Aurelia; Perrett, Rebecca; Stallings, Nancy; Hanley, Neil; Bakke, Marit. 2008. Deoxyribonucleic acid methylation controls cell type-specific expression of steroidogenic factor 1. Endocrinology. 5599-5609.
  • Hoang, Tuyen; Fenne, Ingvild Sveinsgjerd; Cook, Carol Ann; Børud, Bente; Bakke, Marit; Lien, Ernst Asbjørn; Mellgren, Gunnar. 2004. cAMP-dependent protein kinase regulates ubiquitin-proteasome-mediated degradation and subcellular localization of the nuclear receptor coactivator GRIP1. Journal of Biological Chemistry. 49120-49130.
  • Rusten, Marte; Lewis, Aurelia; Bakke, Marit. 2004. NGFI-B is important for induction of SF-1 dependent transcription in response to cAMP. Endocrine Research. 607-607.
  • Børud, Bente; Mellgren, Gunnar; Lund, Johan; Bakke, Marit. 2003. Cloning and Characterization of a Novel Zinc Finger Protein that Modulates the Transcriptional Activity of Nuclear Receptors. Molecular Endocrinology. 2303-2319.
Masters thesis
  • Karki, Aljeena. 2017. DNA Methylation Analyses of the Fetal Leydig cell-specific Enhancer of the Gene Encoding Steroidogenic Factor 1.
  • Dey, Hymonti. 2016. Exchange Protein Directly Activated by cAMP 2 (Epac2): A Novel target for miR-30c.
  • Pedersen, Torhild Thue. 2015. Night work and disturbances in sleep - an animal model.
  • Sabir, Misbah Mohammad. 2015. Molecular Characterization of the Altered Stress Response in Female Mice Deleted for Exchange Proteins Directly Activated by cAMP (Epac).
  • Pedersen, Line. 2014. Characterization of liver functions in Epac knockout models.
  • Islam, Shahinul. 2012. Autoimmune Addison's Disease and DNA Methylation Identification of Differentially Methylated Regions and Development of Methylation Specific PCR for Selected Genes.
  • Åsrud, Kathrine Sivertsen. 2012. Arnt interacts with Miz-1 and activates transcription from the CDKN2B promoter.
  • Bergheim, Inger Riise. 2011. Regulation of tissue-specific expression of Exchange protein directly activated by cAMP 2 (Epac2) by epigenetic mechanisms.
  • Bjånesøy, Trine Elholm. 2010. Epigenetic Regulation of Tissue-Specific Expression of Steroidogenic Factor-1 (SF-1) by DNA Methylation.
  • Chudasama, Kishankumar. 2009. Activation of p21WAFI/CIP1 by ARNT and HIF-α proteins.
  • Lillefosse, Haldis Haukås. 2007. Use of a retroviral vector system to repress DNA methylases by siRNA in adrenocortical cells.
  • Vikse, Elisabeth Lea. 2006. Phosphorylation and Regulation of Steroidogenic Factor-1 by Signal Transduction Pathways in Adrenocortical Cells.
Doctoral dissertation
  • Åsrud, Kathrine Sivertsen. 2017. Physiological Roles of Exchange Factors Directly Activated by cAMP (Epac); Characterization of gene knockout models.
  • Muwonge, Haruna. 2017. Exchange Proteins directly Activated by cAMP (Epac): Physiological roles and Regulation of expression .
  • Aumo, Linda. 2009. Molecular mechanisms of Steroidogenesis:Gene expression and cAMP-induced signaling in adrenocortical cells.
Abstract
  • Høivik, Erling Andre; Bjånesøy, Trine Elholm; Witsø, Solveig Lund; Bakke, Marit. 2010. Tissue Specific Methylation of Intronic Enhancers in the Gene Encoding Steroidogenic Factor 1. Endocrine reviews. 1 pages.
Academic literature review
  • Høivik, Erling Andre; Bjånesøy, Trine Elholm; Bakke, Marit. 2013. Epigenetic regulation of the gene encoding steroidogenic factor-1. 133-139.
  • Høivik, Erling Andre; Lewis, Aurelia; Aumo, Linda; Bakke, Marit. 2010. Molecular aspects of steroidogenic factor 1 (SF-1). 27-39.

More information in national current research information system (CRIStin)