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Ming Ying, PhD

Chief Engineer, Lab manager
  • E-mailMing.Ying@uib.no
  • Phone+47 55 58 60 43
  • Visitor Address
    Jonas Lies vei 91
  • Postal Address
    Postboks 7804
    5020 Bergen
Journal articles
  • Bezem, Maria Teresa; Johannessen, Fredrik Gullaksen; K C, Kunwar Jung; Gundersen, Edvin Tang; Jorge Finnigan, Ana; Ying, Ming; Betbeder, Didier; Herfindal, Lars; Martinez, Aurora. 2018. Stabilization of Human Tyrosine Hydroxylase in Maltodextrin Nanoparticles for Delivery to Neuronal Cells and Tissue. Bioconjugate chemistry. 29: 493-502. doi: 10.1021/acs.bioconjchem.7b00807
  • Scherer, Tanja; Allegri, Gabriella; Sarkissian, Christineh N.; Ying, Ming; Grisch-Chan, Hiu Man; Rassi, Anahita; Winn, Shelley R.; Harding, Cary O.; Martinez, Aurora; Thöny, Beat. 2018. Tetrahydrobiopterin treatment reduces brain L-Phe but only partially improves serotonin in hyperphenylalaninemic ENU1/2 mice. Journal of Inherited Metabolic Disease. 41: 709-718. doi: 10.1007/s10545-018-0150-y
  • Winn, Shelley R; Scherer, Tanja; Thöny, Beat; Ying, Ming; Martinez, Aurora; Weber, Sydney; Raber, Jacob; Harding, Cary O. 2018. Blood phenylalanine reduction corrects CNS dopamine and serotonin deficiencies and partially improves behavioral performance in adult phenylketonuric mice. Molecular Genetics and Metabolism. 123: 6-20. doi: 10.1016/j.ymgme.2017.10.009
  • Jorge Finnigan, Ana; Kleppe, Rune; K C, Kunwar Jung; Ying, Ming; Marie, Michael Bruno Eric; Rios Mondragon, Ivan; Salvatore, Michael F; Saraste, Jaakko; Martinez, Aurora. 2017. Phosphorylation at serine 31 targets tyrosine hydroxylase to vesicles for transport along microtubules. Journal of Biological Chemistry. 292: 14092-14107. doi: 10.1074/jbc.M116.762344
  • Hole, Magnus; Underhaug, Jarl; Diez, Hector; Ying, Ming; Røhr, Åsmund Kjendseth; Jorge-Finnigan, Ana; Fernàndez-Castillo, Noèlia; Garcia-Cazorla, Àngels; Kristoffer Andersson, K.; Teigen, Knut; Martinez, Aurora. 2016. Erratum: Discovery of compounds that protect tyrosine hydroxylase activity through different mechanisms (Biochimica et Biophysica Acta - Proteins and Proteomics (2015) 1854:9 (1078-1089) DOI: 10.1016/j.bbapap.2015.04.030). Biochimica et Biophysica Acta - Proteins and Proteomics. 1864: 317. doi: 10.1016/j.bbapap.2015.11.008
  • Hole, Magnus; Underhaug, Jarl; Diez, Hector; Ying, Ming; Røhr, Åsmund Kjendseth; Jorge Finnigan, Ana; Fernàndez-Castillo, Noèlia; García-Cazorla, Angels; Andersson, K. Kristoffer; Teigen, Knut; Martinez, Aurora. 2015. Discovery of compounds that protect tyrosine hydroxylase activity through different mechanisms. Biochimica et Biophysica Acta - Proteins and Proteomics. 1854: 1078-1089. doi: 10.1016/j.bbapap.2015.04.030
  • Korner, Germaine; Noain, Daniela; Ying, Ming; Hole, Magnus; Flydal, Marte Innselset; Scherer, Tanja; Allegri, Gabriella; Rassi, Anahita; Fingerhut, Ralph; Becu-Villalobos, Damasia; Pillai, Samyuktha; Wueest, Stephan; Konrad, Daniel; Lauber-Biason, Anna; Baumann, Christian R.; Bindoff, Laurence; Martinez, Aurora; Thöny, Beat. 2015. Brain catecholamine depletion and motor impairment in a Th knock-in mouse with type B tyrosine hydroxylase deficiency. Brain. 138: 2948-2963. doi: 10.1093/brain/awv224
  • Totland, Cecilie; Ying, Ming; Haugen, Mette; Mazengia, Kibret Yimer; Storstein, Anette; Aarseth, Jan Harald; Martinez, Aurora; Vedeler, Christian A. 2013. Avidity of onconeural antibodies is of clinical relevance. Cancer Immunology and Immunotherapy. 62: 1393-1396. doi: 10.1007/s00262-013-1442-6
  • Baumann, Anne; Gjerde, Anja Underhaug; Ying, Ming; Svanborg, Catharina; Holmsen, Holm A; Glomm, Wilhelm; Martinez, Aurora; Halskau jr, Øyvind. 2012. HAMLET forms annular oligomers when deposited with phoshpolipid monolayers. Journal of Molecular Biology. 418: 90-102. doi: 10.1016/j.jmb.2012.02.006
  • Bustad, Helene J.; Skjærven, Lars; Ying, Ming; Halskau jr, Øyvind; Baumann, Anne; Rodriguez-Larrea, David; Costas, Miguel; Underhaug, Jarl; Sanchez-Ruiz, Jose Manuel; Martinez, Aurora. 2012. The peripheral binding of 14-3-3gamma to membranes involves isoform-specific histidine residues. PLOS ONE. 7. doi: 10.1371/journal.pone.0049671
  • Sarkissian, Christineh N.; Ying, Ming; Scherer, Tanja; Thöny, Beat; Martinez, Aurora. 2012. The mechanism of BH4-responsive hyperphenylalaninemia-as it Occurs in the ENU1/2 genetic mouse model. Human Mutation. 33: 1464-1473. doi: 10.1002/humu.22128
  • Calvo, Ana C; Scherer, Tanja; Pey, Rodroguez Angel Luis; Ying, Ming; Winge, Ingeborg; Mc Kinney, Jeffrey Alan; Haavik, Jan; Thöny, Beat; Martinez, Aurora. 2010. Effect of pharmacological chaperones on brain tyrosine hydroxylase and tryptophan hydroxylase 2. Journal of Neurochemistry. 114: 853-863. doi: 10.1111/j.1471-4159.2010.06821.x
  • Martinez, Aurora; Calvo, Ana C; Scherer, Tanja; Pey, Rodroguez Angel Luis; Ying, Ming; Winge, Ingeborg; Mc Kinney, Jeffrey Alan; Haavik, Jan; Thöny, Beat. 2010. PHARMACOLOGICAL CHAPERONES FOR THE AROMATIC AMINO ACID HYDROXYLASES. Journal of Inherited Metabolic Disease. 33: S163-S163.
  • Ying, Ming; Pey, Rodroguez Angel Luis; Aarsaether, Niels; Martinez, Aurora. 2010. Phenylalanine hydroxylase expression in primary rat hepatocytes is modulated by oxygen concentration. Molecular Genetics and Metabolism. 101: 279-281. doi: 10.1016/j.ymgme.2010.06.013
  • Halskau jr, Øyvind; Ying, Ming; Baumann, Anne; Kleppe, Rune; Rodriguez-Larrea, David; Almås, Bjørg; Haavik, Jan; Martinez, Aurora. 2009. Three-way interaction between 14-3-3 proteins, the N-terminal region of tyrosine hydroxylase and negatively charged membranes. Journal of Biological Chemistry. 284: 32758-32769. doi: 10.1074/jbc.M109.027706
  • Calvo, Ana C; Pey, Angel; Ying, Ming; Loer, Curtis M.; Martinez, Aurora. 2008. Anabolic function of phenylalanine hydroxylase in Caenorhabditis elegans. The FASEB Journal. 22. doi: 10.1096/fj.08-108522
  • Pey, Angel; Ying, Ming; Cremades, Nunilo; Velazquez-Campoy, Adrian; Scherer, Tanja; Thöny, Beat; Sancho, Javier; Martinez, Aurora. 2008. Identification of pharmacological chaperones as potential therapeutic agents to treat phenylketonuria. Journal of Clinical Investigation. 118: 2858-2867. doi: 10.1172/JCI34355
  • Winge, Ingeborg; Mckinney, Jeffrey; Ying, Ming; D Santos, Clive; Kleppe, Rune; Knappskog, Per; Haavik, Jan. 2008. Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding. Biochemical Journal. 410: 195-204. doi: 10.1042/BJ20071033
  • Kanhema, Tambudzai; Dagestad, Grethe; Panja, Debabrata; Tiron, Adrian; Messaoudi, Elhoucine; Håvik, Bjarte; Ying, Ming; Nairn, Angus C.; Sonenberg, Nahum; Bramham, Clive R. Evjen. 2006. Dual regulation of translation initiation and peptide chain elongation during BDNF-induced LTP in vivo: evidence for compartment-specific translation control. Journal of Neurochemistry. 99: 1328-1337.
  • Ying, Ming; Flatmark, Torgeir. 2006. Binding of the viral immunogenic octapeptide VSV8 to native glucose-regulated protein Grp94 (gp96) and its inhibition by the physiological ligands ATP and Ca2+. The FEBS Journal. 273: 513-522. doi: Sesammendrag
  • Ying, Ming; Sannerud, Ragna; Flatmark, Torgeir; Saraste, J. 2002. Colocalization of Ca2+ATPase and GRP94 with p58 and the effects of thapsigargin on protein recycling suggest the participation of the pre-Golgi intermediate compartment in intracellular Ca2+ storage. European Journal of Cell Biology. 81: 469-524.
  • Ying, Ming; Flatmark, Torgeir; Saraste, J. 2000. The p58-positive pre-Golgi intermediates consist of distinct subpopulations of particles that show differential binding of COPI and COPII coats and contain vacuolar H+ - ATPase. Journal of Cell Science. 113: 3623-3638.
  • Palokangas, H.; Ying, Ming; Väänänen, K.; Saraste, Jaakko. 1998. Retrograde transport from the pre-Golgi intermediate compartment and the Golgi complex is affected by the vacuolar H -ATPase inhibitor bafilomycin. Molecular Biology of the Cell. 9: 3561-3578.
Reports and theses
  • Ying, Ming. 2001. Structural and Functional Organisation of the Pre-Golgi Intermediate Compartment. Dr.med.. -.

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