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Ming Ying

Chief Engineer, Lab manager (PhD)
  • E-mailMing.Ying@uib.no
  • Phone+47 55 58 60 43
  • Visitor Address
    Jonas Lies vei 91
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • K C, Kunwar Jung; Himmelreich, Nastassja; Prestegård, Karina Skjervheim; Shi, Tie-Jun; Scherer, Tanja; Ying, Ming; Jorge Finnigan, Ana; Thöny, Beat; Blau, Nenad; Martinez, Aurora. 2019. Phenylalanine hydroxylase variants interact with the co-chaperone DNAJC12. Human Mutation.
  • Scherer, Tanja; Allegri, Gabriella; Sarkissian, Christineh N.; Ying, Ming; Grisch-Chan, Hiu Man; Rassi, Anahita; Winn, Shelley R.; Harding, Cary O.; Martinez, Aurora; Thöny, Beat. 2018. Tetrahydrobiopterin treatment reduces brain L-Phe but only partially improves serotonin in hyperphenylalaninemic ENU1/2 mice. Journal of Inherited Metabolic Disease. 709-718.
  • Bezem, Maria Teresa; Johannessen, Fredrik Gullaksen; K C, Kunwar Jung; Gundersen, Edvin Tang; Jorge Finnigan, Ana; Ying, Ming; Betbeder, Didier; Herfindal, Lars; Martinez, Aurora. 2018. Stabilization of Human Tyrosine Hydroxylase in Maltodextrin Nanoparticles for Delivery to Neuronal Cells and Tissue. Bioconjugate chemistry. 493-502.
  • Winn, Shelley R; Scherer, Tanja; Thöny, Beat; Ying, Ming; Martinez, Aurora; Weber, Sydney; Raber, Jacob; Harding, Cary O. 2018. Blood phenylalanine reduction corrects CNS dopamine and serotonin deficiencies and partially improves behavioral performance in adult phenylketonuric mice. Molecular Genetics and Metabolism. 6-20.
  • Jorge Finnigan, Ana; Kleppe, Rune; K C, Kunwar Jung; Ying, Ming; Marie, Michael Bruno Eric; Rios Mondragon, Ivan; Salvatore, Michael F; Saraste, Jaakko; Martinez, Aurora. 2017. Phosphorylation at serine 31 targets tyrosine hydroxylase to vesicles for transport along microtubules. Journal of Biological Chemistry. 14092-14107.
  • Hole, Magnus; Underhaug, Jarl; Diez, Hector; Ying, Ming; Røhr, Åsmund Kjendseth; Jorge Finnigan, Ana; Fernàndez-Castillo, Noèlia; García-Cazorla, Angels; Andersson, K. Kristoffer; Teigen, Knut; Martinez, Aurora. 2015. Discovery of compounds that protect tyrosine hydroxylase activity through different mechanisms. Biochimica et Biophysica Acta - Proteins and Proteomics. 1078-1089.
  • Korner, Germaine; Noain, Daniela; Ying, Ming; Hole, Magnus; Flydal, Marte Innselset; Scherer, Tanja; Allegri, Gabriella; Rassi, Anahita; Fingerhut, Ralph; Becu-Villalobos, Damasia; Pillai, Samyuktha; Wueest, Stephan; Konrad, Daniel; Lauber-Biason, Anna; Baumann, Christian R.; Bindoff, Laurence; Martinez, Aurora; Thöny, Beat. 2015. Brain catecholamine depletion and motor impairment in a Th knock-in mouse with type B tyrosine hydroxylase deficiency. Brain. 2948-2963.
  • Totland, Cecilie; Ying, Ming; Haugen, Mette; Mazengia, Kibret Yimer; Storstein, Anette; Aarseth, Jan Harald; Martinez, Aurora; Vedeler, Christian A. 2013. Avidity of onconeural antibodies is of clinical relevance. Cancer Immunology and Immunotherapy. 1393-1396.
  • Bustad, Helene J.; Skjærven, Lars; Ying, Ming; Halskau jr, Øyvind; Baumann, Anne; Rodriguez-Larrea, David; Costas, Miguel; Underhaug, Jarl; Sanchez-Ruiz, Jose Manuel; Martinez, Aurora. 2012. The peripheral binding of 14-3-3gamma to membranes involves isoform-specific histidine residues. PLOS ONE.
  • Sarkissian, Christineh N.; Ying, Ming; Scherer, Tanja; Thöny, Beat; Martinez, Aurora. 2012. The mechanism of BH4-responsive hyperphenylalaninemia-as it Occurs in the ENU1/2 genetic mouse model. Human Mutation. 1464-1473.
  • Baumann, Anne; Gjerde, Anja Underhaug; Ying, Ming; Svanborg, Catharina; Holmsen, Holm A; Glomm, Wilhelm; Martinez, Aurora; Halskau jr, Øyvind. 2012. HAMLET forms annular oligomers when deposited with phoshpolipid monolayers. Journal of Molecular Biology. 90-102.
  • Ying, Ming; Pey, Rodroguez Angel Luis; Aarsaether, Niels; Martinez, Aurora. 2010. Phenylalanine hydroxylase expression in primary rat hepatocytes is modulated by oxygen concentration. Molecular Genetics and Metabolism. 279-281.
  • Calvo, Ana C; Scherer, Tanja; Pey, Rodroguez Angel Luis; Ying, Ming; Winge, Ingeborg; Mc Kinney, Jeffrey Alan; Haavik, Jan; Thöny, Beat; Martinez, Aurora. 2010. Effect of pharmacological chaperones on brain tyrosine hydroxylase and tryptophan hydroxylase 2. Journal of Neurochemistry. 853-863.
  • Halskau jr, Øyvind; Ying, Ming; Baumann, Anne; Kleppe, Rune; Rodriguez-Larrea, David; Almås, Bjørg; Haavik, Jan; Martinez, Aurora. 2009. Three-way interaction between 14-3-3 proteins, the N-terminal region of tyrosine hydroxylase and negatively charged membranes. Journal of Biological Chemistry. 32758-32769.
  • Pey, Angel; Ying, Ming; Cremades, Nunilo; Velazquez-Campoy, Adrian; Scherer, Tanja; Thöny, Beat; Sancho, Javier; Martinez, Aurora. 2008. Identification of pharmacological chaperones as potential therapeutic agents to treat phenylketonuria. Journal of Clinical Investigation. 2858-2867.
  • Calvo, Ana C; Pey, Angel; Ying, Ming; Loer, Curtis M.; Martinez, Aurora. 2008. Anabolic function of phenylalanine hydroxylase in Caenorhabditis elegans. The FASEB Journal.
  • Winge, Ingeborg; Mckinney, Jeffrey; Ying, Ming; D Santos, Clive; Kleppe, Rune; Knappskog, Per; Haavik, Jan. 2008. Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding. Biochemical Journal. 195-204.
  • Kanhema, Tambudzai; Dagestad, Grethe; Panja, Debabrata; Tiron, Adrian; Messaoudi, Elhoucine; Håvik, Bjarte; Ying, Ming; Nairn, Angus C.; Sonenberg, Nahum; Bramham, Clive R. Evjen. 2006. Dual regulation of translation initiation and peptide chain elongation during BDNF-induced LTP in vivo: evidence for compartment-specific translation control. Journal of Neurochemistry. 1328-1337.
  • Ying, Ming; Flatmark, Torgeir. 2006. Binding of the viral immunogenic octapeptide VSV8 to native glucose-regulated protein Grp94 (gp96) and its inhibition by the physiological ligands ATP and Ca2+. The FEBS Journal. 513-522.
  • Ying, Ming; Sannerud, Ragna; Flatmark, Torgeir; Saraste, J. 2002. Colocalization of Ca2+ATPase and GRP94 with p58 and the effects of thapsigargin on protein recycling suggest the participation of the pre-Golgi intermediate compartment in intracellular Ca2+ storage. European Journal of Cell Biology. 469-524.
  • Ying, Ming; Flatmark, Torgeir; Saraste, J. 2000. The p58-positive pre-Golgi intermediates consist of distinct subpopulations of particles that show differential binding of COPI and COPII coats and contain vacuolar H+ - ATPase. Journal of Cell Science. 3623-3638.
  • Palokangas, H.; Ying, Ming; Väänänen, K.; Saraste, Jaakko. 1998. Retrograde transport from the pre-Golgi intermediate compartment and the Golgi complex is affected by the vacuolar H -ATPase inhibitor bafilomycin. Molecular Biology of the Cell. 3561-3578.
Academic lecture
  • Saraste, Jaakko; Ying, Ming; Palokangas, H. 1998. The pre-Golgi intermediate compartment and protein recycling at the ER-Golgi boundary: Studies of p58-binding ligands and the effect of transport inhibitors.
  • Saraste, Jaakko; Ying, Ming; Palokangas, H. 1997. Protein transport between the rough endoplasmic reticulum and the Golgi apparatus: role of the intermediate compartment.
  • Ying, Ming; Hendershot, L; Saraste, Jaakko. 1997. Identification of protein ligands that bind to p58 in the early secretory pathway.
Doctoral dissertation
  • Ying, Ming. 2001. Structural and Functional Organisation of the Pre-Golgi Intermediate Compartment. -.
Abstract
  • Martinez, Aurora; Calvo, Ana C; Scherer, Tanja; Pey, Rodroguez Angel Luis; Ying, Ming; Winge, Ingeborg; Mc Kinney, Jeffrey Alan; Haavik, Jan; Thöny, Beat. 2010. PHARMACOLOGICAL CHAPERONES FOR THE AROMATIC AMINO ACID HYDROXYLASES. Journal of Inherited Metabolic Disease. S163-S163.
Errata
  • Hole, Magnus; Underhaug, Jarl; Diez, Hector; Ying, Ming; Røhr, Åsmund Kjendseth; Jorge-Finnigan, Ana; Fernàndez-Castillo, Noèlia; Garcia-Cazorla, Àngels; Kristoffer Andersson, K.; Teigen, Knut; Martinez, Aurora. 2016. Erratum: Discovery of compounds that protect tyrosine hydroxylase activity through different mechanisms (Biochimica et Biophysica Acta - Proteins and Proteomics (2015) 1854:9 (1078-1089) DOI: 10.1016/j.bbapap.2015.04.030). Biochimica et Biophysica Acta - Proteins and Proteomics. 317.

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