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Monica Jordheim's picture

Monica Jordheim

Associate Professor, Marine natural products - Analytical organic chemistry
Department of Chemistry
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  • E-mailmonica.jordheim@uib.no
  • Phone+47 55 58 35 48
  • Visitor Address
    Allégaten 41
    Realfagbygget
    5007 Bergen
    Room 
    3032
  • Postal Address
    Postboks 7803
    5020 Bergen

Natural Products and Marine Bioresource Development

https://www.instagram.com/jordheimresearchmnp/

  • Qualitative and quantitative analysis of high value natural products from marine sources, particularly focused on polyphenols and pigments in seaweeds and seagrasses
  • Chemical analysis of marine deep-sea materials collected in Norway
  • Bioprospecting and search for novel compounds
  • Chemical ecology, biosystematics studies and interdisciplinary applications

Monica Jordheim´s main research interests are to enhance scientific knowledge and application value of various natural products. Jordheim has over twenty years of experience in quantification and identification of natural products, inluding full molecular elucidation.

Because of the structural diversity, characterization of natural products requires an integrated analytical approach including optimized extraction techniques, multiple steps of chromatography, High Resolutions Mass spectrometry (HRMS) and high field NMR analysis.

Jordheim is the:

Jordheim is Head of Education at the Department of Chemistry, working with educational quality and development.

 

B.Sc. and M.Sc.-projects:

Organic analytical projects within bioprospecting and marine bioresource development (seaweeds (harvested and farmed), seagrasses, aquatic angiosperms, deep sea materials). Severel of the projects have industrial partners. 

 

Courses:

KJEM235 https://www.uib.no/emne/KJEM235    (10 ECTS)

Objectives and Content

The course addresses analysis of organic compounds using spectroscopic methods as infrared (IR), ultraviolet-visible (UV-Vis) and nuclear magnetic resonance (NMR) spectroscopy, as well as mass spectrometry (MS). The course concentrates on interpretation of data, and the focus will be to understand and to utilize data from NMR and MS.

Academic article
  • Show author(s) (2023). Characterization of high value products in the side-stream of Laminaria hyperborea alginate production - Targeting the phenolic content. Algal Research.
  • Show author(s) (2022). Seasonal variation of phenolic compounds in Zostera marina (Zosteraceae) from the Baltic Sea . Phytochemistry.
  • Show author(s) (2022). Advancing quantification methods for polyphenols in brown seaweeds—applying a selective qNMR method compared with the TPC assay. Phytochemical Analysis. 1-12.
  • Show author(s) (2021). Variation in Phenolic Chemistry in Zostera marina Seagrass Along Environmental Gradients. Plants. 17 pages.
  • Show author(s) (2020). Anthocyanin profile and antioxidant property of anti-asthma flowers of cordyline terminalis (L.) Kunth (Agavaceae). Natural Product Communications. 1-7.
  • Show author(s) (2020). Anthocyanin Profile and Antioxidant Activity of Edible Leaves of Dissotis brazzae Cogn (Melastomataceae). Journal of Food and Nutrition Sciences. 139-145.
  • Show author(s) (2019). Quantification of polyphenols in seaweeds: A case study of Ulva intestinalis. Antioxidants. 1-15.
  • Show author(s) (2019). Auronidins are a previously unreported class of flavonoid pigments that challenges when anthocyanin biosynthesis evolved in plants. Proceedings of the National Academy of Sciences of the United States of America. 20232-20239.
  • Show author(s) (2019). Anthocyanins from mauve flowers of Erlangea tomentosa (Bothriocline longipes) based on erlangidin – The first reported natural anthocyanidin with C-ring methoxylation. Phytochemistry Letters. 225-230.
  • Show author(s) (2018). Characterization of Polyphenolic Content in the Aquatic Plants Ruppia cirrhosa and Ruppia maritima —A Source of Nutritional Natural Products. Molecules. 1-15.
  • Show author(s) (2017). Characterization and seasonal variation of individual flavonoids in Zostera marina and Zostera noltii from Norwegian coastal waters. Biochemical Systematics and Ecology. 42-50.
  • Show author(s) (2016). Isolation and Identification of Flavonoids Found in Zostera marina Collected in Norwegian Coastal Waters. American Journal of Plant Sciences. 1163-1172.
  • Show author(s) (2016). High concentrations of aromatic acylated anthocyanins found in cauline hairs in Plectranthus ciliatus. Phytochemistry. 27-34.
  • Show author(s) (2014). Purple anthocyanin colouration on lower (abaxial) leaf surface of Hemigraphis colorata (Acanthaceae). Phytochemistry. 141-146.
  • Show author(s) (2014). Anthocyanins and their differential accumulation in the floral and vegetative tissues of a shrub species (Rhabdothamnus solandri A. Cunn). Scientia Horticulturae. 29-35.
  • Show author(s) (2012). New anthocyanidin and anthocyanin pigments from blue plumbago. Journal of Agricultural and Food Chemistry. 1510-1515.
  • Show author(s) (2011). Primitive anthocyanin from flowers of three hemiparasitic African mistletoes. Archives of Applied Science Research. 1-5.
  • Show author(s) (2011). Identification of Cyanidin 3-O-β-(6″-(3-Hydroxy-3-methylglutaroyl)glucoside) and Other Anthocyanins from Wild and Cultivated Blackberries. Journal of Agricultural and Food Chemistry. 7436-7440.
  • Show author(s) (2011). Anthocyanins from ornamental flowers of red frangipani, Plumeria rubra. Scientia Horticulturae. 840-843.
  • Show author(s) (2011). Anthocyanins from Fuchsia Flowers. Natural Product Communications. 35-40.
  • Show author(s) (2011). Anthocyanidin 3-galactosides from flowers of Abrus canescens Bak Full Text. African Journal of Pure and Applied Chemistry. 356-360.
  • Show author(s) (2010). Novel aspects of the flowers and floral pigmentation of two Cleome species (Cleomaceae), C. hassleriana and C. serrulata. Biochemical Systematics and Ecology. 361-369.
  • Show author(s) (2010). Anthocyanins with unusual furanose sugar (apiose) from leaves of Synadenium grantii (Euphorbiaceae). Phytochemistry. 1558-1563.
  • Show author(s) (2009). Acylated anthocyanins in inflorescence of spider flower (Cleome hassleriana). Phytochemistry. 740-745.
  • Show author(s) (2008). New anthocyanins from stem bark of castor, Ricinus communis. Natural Product Communications. 1497-1500.
  • Show author(s) (2007). Reactivity of anthocyanins and pyranoanthocyanins. Studies on aromatic hydrogen-deuterium exchange reactions in methanol. Journal of Agricultural and Food Chemistry. 8261-8268.
  • Show author(s) (2007). Molar Absorptivities and Reducing Capacity of Pyranoanthocyanins and Other Anthocyanins. Journal of Agricultural and Food Chemistry. 10591-10598.
  • Show author(s) (2007). Anthocyanins in berries of Ribes including gooseberry cultivars with a high content of acylated pigments. Journal of Agricultural and Food Chemistry.
  • Show author(s) (2007). Anthocyanins in berries of Ribes including gooseberry cultivars with a high content of acylated pigments. Journal of Agricultural and Food Chemistry. 5529-5535.
  • Show author(s) (2007). Anthocyanins in Caprifoliaceae. Biochemical Systematics and Ecology. 153-159.
  • Show author(s) (2006). Preparative isolation and NMR characterization of carboxypyranoanthocyanins. Journal of Agricultural and Food Chemistry. 3572 -3577.
  • Show author(s) (2006). Characterization of Hemiacetal Forms of Anthocyanidin 3-O-b-Glycopyranosides. Journal of Agricultural and Food Chemistry. 9340-9346.
  • Show author(s) (2006). Anthocyanins from flowers of Hippeastrum cultivars. Scientia Horticulturae. 262-266.
Lecture
  • Show author(s) (2022). Shaping European Research Leaders for Marine Sustainability - the algal component .
  • Show author(s) (2021). Totalutnyttelse av marine ressurser og utvikling av norsk kompetanse – hvordan får vi dette til? Targeting High-Value Products: The Next Level .
  • Show author(s) (2020). Tang og tare - den nye mirakelmaten? II.
  • Show author(s) (2019). Tang og tare - den nye mirakelmaten? I.
  • Show author(s) (2019). Analyse i marin kjemi.
  • Show author(s) (2018). Bruk av spektroskopiske metoder i marin naturstoffkjemi.
  • Show author(s) (2016). Organisk analyse og naturstoffkjemi - hvilke verktøy trenger vi?
  • Show author(s) (2015). Naturstoffkjemi - skattejakt?
Popular scientific lecture
  • Show author(s) (2009). Fra blåbær til medisin - fargestoffer i frukt og grønnsaker.
  • Show author(s) (2007). Fargerik mat og helse: Hva kan vi hente ut av antocyaner og andre flavonoider?
  • Show author(s) (2006). Blåbær er ikke bare blåbær - blåbærforskning ved kjemisk institutt.
  • Show author(s) (2006). Antocyaner - vin og helseeffekter.
Academic lecture
  • Show author(s) (2020). MYCOTOXIN AND METABOLITES DETERMINATION IN NORWEGIAN FISH FEEDS USING LC-MS/MS INSTRUMENTS.
  • Show author(s) (2014). New anthocyanin with potential beneficial nutraceutical and colorant properties isolated from Cyphostemma adenocaule.
  • Show author(s) (2014). Anthocyanins with new anthocyanidin A-ring substitution patterns.
  • Show author(s) (2013). Nutraceutical potential of Dissotis brazzae Cogn. (Melastomataceae) with respect to anthocyanins.
  • Show author(s) (2013). Differences in anthocyanin content of food and natural sources correlated with differences in anthocyanin chemistry and properties.
  • Show author(s) (2013). Anthocyanins from Pink-mauve flowers of Draceana terminalis (Asparagaceae).
  • Show author(s) (2011). The rise and fall of anthocyanins.
  • Show author(s) (2011). Anthocyanin sources, diversity and properties.
  • Show author(s) (2011). Anthocyanin equilibrium forms.
  • Show author(s) (2009). Chemistry of Anthocyanin-Based Colours in Plants.
  • Show author(s) (2008). Hydrogen-deuterium exchange rates of various anthocyanin classes as basis for reactivity studies.
  • Show author(s) (2008). Anthocyanins - Food Applications.
  • Show author(s) (2007). Biological functionality of anthocyanins expressed through structure details.
  • Show author(s) (2007). Advances in the field of anthocyanins.
  • Show author(s) (2006). Characterization of novel flavonoid classes by NMR spectroscopy.
  • Show author(s) (2005). The anthocyanins: A review on occurence, chemistry and properties during the last decade.
  • Show author(s) (2005). Anthocyanins from ripe edible fruits of wild Carissa edulis.
Thesis at a second degree level
  • Show author(s) (2013). ISOLATION AND STRUCTURE ELUCIDATION OF ANTHOCYANIN-PIGMENTS FROM STRAWBERRY - Complete characterization of quinonoidal and hemiketal forms.
  • Show author(s) (2003). Plantepigmenter i bær. Isolering, karakterisering og kjemotaxonomi.
Masters thesis
  • Show author(s) (2022). Quantification of fucoidan isolated from Laminaria hyperborea using two different colorimetric assays and qNMR method.
  • Show author(s) (2022). Develop a multi-analyte screening method for authorized and prohibited veterinary drugs in seafood by using HPLC-HR-MS .
  • Show author(s) (2021). Quantification of polyphenols in seaweeds,Total Phenolic Concentration assay (TPC) .
  • Show author(s) (2021). Qualitative Analysis of Flavonoid content in Marine Plant, Lysimachia maritima .
  • Show author(s) (2020). Method development using LC-MS/MS and LC-IMS-QTOF MS to determine mycotoxins in fish feed samples .
  • Show author(s) (2020). Karakterisering og kvantifisering av flavonoider i den akvatiske planten vanlig Tjønnaks (Potamogeton natans) .
  • Show author(s) (2020). Analysis of the marine sponge Pachymatisma normani.
  • Show author(s) (2019). Qualitative and Quantitative Analysis of Polyphenols and Pigments in Marine Sources - Zostera marina and Cultivated Microalgae - .
  • Show author(s) (2019). Polyphenols and Pigments in Marine Algae.
  • Show author(s) (2018). Search for Flavonoids in Macroalgae, extraction, detection and quantification.
  • Show author(s) (2013). Methods for purification and isolation of anthocyanins from peat moss (Sphagnum sp.) and black chokeberry (Aronia melanocarpa).
  • Show author(s) (2013). Karakterisering av plantepigmenter, med vekt på quinonoidale former av antocyaner.
  • Show author(s) (2011). Anthocyanpigment i blodappelsin (Citrus sinensis L. Osbeck) Nye sambindingar og stabilitetsstudiar.
  • Show author(s) (2011). Analyse av antocyaner med unike skjellett isolert fra Torvmose.
Doctoral dissertation
  • Show author(s) (2021). Novel and colorful flavonoids - characterization, secondary structures and properties.
  • Show author(s) (2018). Analysis of polyphenolic content in marine and aquatic angiosperms from Norwegian coastal waters.
  • Show author(s) (2013). Identification of New Anthocyanins and Secondary Anthocyanidin Structures and their impact on Anthocyanin Properties.
  • Show author(s) (2007). Isolation, identification and properties of pyranoanthocyanins and anthocyanin forms.
Academic chapter/article/Conference paper
  • Show author(s) (2013). Basic anthocyanin chemistry and dietary source. 78 pages.
  • Show author(s) (2010). Chemistry of flavonoid-based colors in plants. 67 pages.
  • Show author(s) (2006). The Anthocyanins. 81 pages.
Encyclopedia article
  • Show author(s) (2010). Anthocyanins. . In:
    • Show author(s) (2010). Encyclopedia of Life Sciences.
Poster
  • Show author(s) (2022). Targeting high-value products from the epiphytes of Laminaria hyperborea.
  • Show author(s) (2022). Polyphenols in kelp: A Case Study of Laminaria hyperborea.
  • Show author(s) (2020). Extraction optimization for high value products from Laminaria hyperborea.
  • Show author(s) (2016). Analysis of Flavonoids in the Seagrass Zostera Marina L.
  • Show author(s) (2015). Anthocyanins from Erlangea tomentosa based on erlangidin, an anthocyanidin with 3-methoxylation.
  • Show author(s) (2013). Special anthocyanin structures behind colouration of abaxial leaves of Hemigraphis colorata.
  • Show author(s) (2013). Diagnostic analysis of anthocyanins with new anthocyanidin A-ring substitution patterns.
  • Show author(s) (2012). Characterization of the quinonoidal form of the anthocyanin malvidin 3-glucoside by NMR.
  • Show author(s) (2011). Sphagnorubins from peat mosses, Sphagnum spp.
  • Show author(s) (2011). New anthocyanins in Plectranthus ciliatus and their distribution in trichomes, internodes and leaves.
  • Show author(s) (2011). Cyanidin 3-O-β-(6''-(3-hydroxy-3-methylglutaroyl)glucoside and other anthocyanins in blackberries and blood oranges.
  • Show author(s) (2011). Correction of anthocyanin identity in blood orange (Citrus sinensis L. Osbeck).
  • Show author(s) (2010). Natural anthocyanidins with dimethoxylated A-rings from Plumbago auriculata.
  • Show author(s) (2008). Reactivity studies by NMR on anthocyanins occurring in fruits and berries.
  • Show author(s) (2007). The impact of anthocyanin purity in antioxidant measurements.
  • Show author(s) (2006). NMR characterization of various forms of anthocyanin 3-glucosides in deuterated methanolic solutions with and without acid.
  • Show author(s) (2006). Characterization of 5-carboxypyranoanthocyanins.
  • Show author(s) (2005). Nutritional aspects of anthocyanin pigments.
  • Show author(s) (2004). Characterization of Pyranoanthocyanins.
Article in business/trade/industry journal
  • Show author(s) (2021). The under-explored chemistry of seaweeds. NBS-nytt. 14-18.
  • Show author(s) (2016). Improving students learning process in a small class setting ‐ chemistry course in spectroscopy. UPED-skrift.

More information in national current research information system (CRIStin)

Jordheim Research Group:

Postdoctoral researchers:

  • Diego Rodriguez Hernandes (SEAS, Horizon 2020 -Marie Skłodowska-Curie grant agreement No 101034309)
  • Liaqat Zeb (SEAS, Horizon 2020 -Marie Skłodowska-Curie grant agreement No 101034309)

PhD-students:

MSc-students:

 

Fields of competence 
Bioprospecting
Chemical Ecology
Chromatography
Marine natural products chemistry
Mass Spectrometry
NMR
Organic Analytical Chemistry
Quantitative analysis

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