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Odd André Karlsen

Associate Professor
  • E-mailOdd.Karlsen@uib.no
  • Phone+47 55 58 46 51
  • Visitor Address
    Thormøhlensgt. 53 A/B
  • Postal Address
    Postboks 7803
    5020 Bergen
Academic article
  • 2020. Proteomics and lipidomics analyses reveal modulation of lipid metabolism by perfluoroalkyl substances in liver of Atlantic cod (Gadus morhua). Aquatic Toxicology. 13 pages.
  • 2020. Molecular and Functional Properties of the Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. Environmental Science and Technology.
  • 2020. Expression and localization of the aryl hydrocarbon receptors and cytochrome P450 1A during early development of Atlantic cod (Gadus morhua). Aquatic Toxicology. 10 pages.
  • 2019. Modulation of neuro-dopamine homeostasis in juvenile female Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances. Environmental Science and Technology. 7036-7044.
  • 2019. Effects of agricultural pesticides in aquafeeds on wild fish feeding on leftover pellets near fish farms. Frontiers in Genetics. 1-18.
  • 2019. Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) caged at a capped waste disposal site in Kollevåg, Western Norway. Marine Environmental Research. 39-51.
  • 2019. Analysis of immunoglobulin and T cell receptor gene expression in ballan wrasse (Labrus bergylta) revealed an extraordinarily high IgM expression in the gut. Fish and Shellfish Immunology. 650-658.
  • 2018. Sequence variations in pxr (nr1i2) from Zebrafish (Danio rerio) strains affect nuclear receptor function. Toxicological Sciences. 28-39.
  • 2018. RNA-Seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision-cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol. Aquatic Toxicology. 174-186.
  • 2018. LC-MS/MS based profiling and dynamic modelling of the steroidogenesis pathway in adrenocarcinoma H295R cells. Toxicology in Vitro. 332-341.
  • 2018. Independent losses of a xenobiotic receptor across teleost evolution. Scientific Reports. 1-13.
  • 2018. Effects of defined mixtures of POPs and endocrine disruptors on the steroid metabolome of the human H295R adrenocortical cell line. Chemosphere. 328-339.
  • 2018. Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays. Science of the Total Environment. 1640-1648.
  • 2017. Quantitative proteomics analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153. Aquatic Toxicology. 19-28.
  • 2016. Transcriptomic profiling of Methylococcus capsulatus (Bath)during growth with two different methane monooxygenases. MicrobiologyOpen. 254-267.
  • 2016. Quantitative analyses of the hepatic proteome of methylmercury-exposed Atlantic cod (Gadus morhua) suggest oxidative stress-mediated effects on cellular energy metabolism. BMC Genomics. 1-15.
  • 2016. Characterization of IgM in Norwegian cleaner fish (lumpfish and wrasses). Fish and Shellfish Immunology. 9-17.
  • 2016. Assessment of the environmental quality of coastal sediments by using a combination of in vitro bioassays. Marine Pollution Bulletin. 53-61.
  • 2014. Precision-cut liver slices of Atlantic cod (Gadus morhua): An in vitro system for studying the effects of environmental contaminants. Aquatic Toxicology. 110-115.
  • 2014. Liver transcriptome analysis of Atlantic cod (Gadus morhua) exposed to PCB 153 indicates effects on cell cycle regulation and lipid metabolism. BMC Genomics.
  • 2014. CorA is a copper repressible surface-associated copper(I)-binding protein produced in Methylomicrobium album BG8. PLOS ONE.
  • 2014. Alterations in the atlantic COD (Gadus morhua) hepatic thiol-proteome after methylmercury exposure. Journal of Toxicology and Environmental Health, Part A. 650-662.
  • 2013. Global transcriptome analysis of Atlantic cod (Gadus morhua) liver after in vivo methylmercury exposure suggests effects on energy metabolism pathways. Aquatic Toxicology. 314-325.
  • 2012. The Methylococcus capsulatus (Bath) Secreted Protein, MopE*, Binds Both Reduced and Oxidized Copper. PLOS ONE. 10 pages.
  • 2012. Mass spectrometric analyses of microsomal cytochrome P450 isozymes isolated from beta-naphthoflavone-treated Atlantic cod (Gadus morhua) liver reveal insights into the cod CYPome. Aquatic Toxicology. 2-10.
  • 2012. Conservation and divergence of chemical defense system in the tunicate Oikopleura dioica revealed by genome wide response to two xenobiotics. BMC Genomics. 17 pages.
  • 2011. Integrative Environmental Genomics of Cod (Gadus morhua): The Proteomics Approach. Journal of Toxicology and Environmental Health, Part A. 494-507.
  • 2010. Identification of a bacterial di-haem cytochrome c peroxidase from Methylomicrobium album BG8. Microbiology. 2682-2690.
  • 2009. Human Naa50p (Nat5/San) Displays Both Protein N-alpha- and N-epsilon-Acetyltransferase Activity. Journal of Biological Chemistry. 31122-31129.
  • 2008. The presence of multiple c-type cytochromes at the surface of the methanotrophic bacterium Methylococcus capsulatus (Bath) is regulated by copper. Molecular Microbiology. 15-26.
  • 2008. An oxidized tryptophan facilitates copper binding in Methylococcus capsulatus-secreted protein MopE. Journal of Biological Chemistry. 13897-13904.
  • 2006. Analysing the outer membrane subproteome of Methylococcus capsulatus (Bath) using proteomics and novel biocomputing tools. Archives of Microbiology. 362-377.
  • 2005. Identification of a copper-repressible cytochrome c peroxidase of Methylococcus capsulatus (Bath); a member of a novel group of the bacterial di-heme cytochrome c peroxidase family of proteins. The FEBS Journal. 6324-6335.
  • 2005. Characterisation of a prokaryotic hemerythrin from the methanotrophic bacterium Methylococcus capsulatus (Bath). The FEBS Journal. 2428-2440.
  • 2004. The core 2 ß-1,6-N-acetylglucosaminyltransferase-M encoded by bovine herpesvirus 4 is not essential for virus replication despite contributing to post-translational modifications of structural proteins. Journal of General Virology. 355-367.
  • 2003. The surface-associated and secreted MopE protein of Methylococcus capsulatus (Bath) responds to changes in the concentration of copper in the growth medium. Applied and Environmental Microbiology. 2386-2388.
  • 2003. Multiple polypeptide forms observed in two-dimensional gels of Methylococcus capsulatus (Bath) polypeptides are generated during the separation procedure. Electrophoresis. 757-761.
Lecture
  • 2019. Chemical warfare in the marine environment.
  • 2018. Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.
Academic lecture
  • 2020. Polar cod and Goliat: How an oil spill may affect polar cod reproduction.
  • 2020. Adapting a liver slice culture method for ex vivo toxicological studies in arctic and sub-arctic fish species during sampling cruises.
  • 2020. ANTIESTROGENIC EFFECTS OF BENZO[a]PYRENE REVEALED BY TRANSCRIPTOME ANALYSIS IN POLAR COD LIVER SLICE CULTURE.
  • 2020. A multi-omics approach to study Ppar-mediated regulation of lipid metabolism in Atlantic cod (Gadus morhua).
  • 2019. dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR.
  • 2019. Toxicogenomic responses in Atlantic cod (Gadus morhua) after treatment with selected environmental contaminants in vivo and ex vivo.
  • 2019. The chemical defensome of Atlantic cod (Gadus morhua).
  • 2019. In vitro assessment of estrogenic and androgenic effects of bisphenols on Atlantic cod (Gadus morhua).
  • 2019. Effects of agricultural pesticides in aquafeeds on wild fish feeding on leftover pellets near fish farms. Conference talk.
  • 2019. EFFECTS OF SELECTED ENVIRONMENTAL ESTROGENS ON EXPRESSION OF FIBROBLAST GROWTH FACTOR SIGNALING PATHWAY GENES IN THE LIVER OF ATLANTIC COD (GADUS MORHUA) IN VIVO AND EX VIVO.
  • 2019. Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances.
  • 2019. Biological responses of Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances.
  • 2019. Assessment of endocrine disrupting effects of bisphenols in Atlantic cod (Gadus morhua) using luciferase reporter assays and precision-cut liver slices.
  • 2019. Agricultural pesticides in aquafeeds might harm wild fish feeding on leftover pellets near fish farms.
  • 2018. dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA).
  • 2018. The nuclear receptor complement of Atlantic cod (Gadus morhua) as potential targets for endocrine disrupting compounds.
  • 2018. RNA-seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol.
  • 2018. RNA-seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol.
  • 2018. Modelling the chemical defensome networks --- a dynamic visualisation of the involved genes and interactions in two fish species and human.
  • 2018. Modelling the chemical defensome network - a dynamic visualisation of the involved genes and pathways in two fish species and humans .
  • 2018. Modelling The Chemical Defensome Networks - A Comparative Dynamic Visualisation Of The Involved Genes And Interactions In Two Fish Species And Humans.
  • 2018. Establishing a cellfree method for xenobiotic detection using ligand activated receptors from the Atlantic cod, Gadus morhua.
  • 2018. Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway .
  • 2018. Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway .
  • 2018. Characterization of the aryl hydrocarbon receptors Ahr1a and Ahr2a in Atlantic cod (Gadus morhua).
  • 2018. Characterization of the aryl hydrocarbon receptors Ahr1a and Ahr2a in Atlantic cod (Gadus morhua).
  • 2018. Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.
  • 2018. Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.
  • 2018. Agonistic and antagonistic effects of perfluorinated compounds on Atlantic cod (Gadus morhua) PPARαa and PPARαb nuclear receptors.
  • 2017. PRECISION-CUT LIVER SLICES (PCLS) FOR TOXICOGENOMIC STUDIES IN ATLANTIC COD (Gadus morhua): THE dCOD 1.0 PROJECT.
  • 2017. Integrative transcriptome and proteome analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153.
  • 2017. Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway .
  • 2017. CHARACTERIZATION OF THE ARYL HYDROCARBON RECEPTORS AHR1B AND AHR2 IN ATLANTIC COD (GADUS MORHUA).
  • 2016. Toxicogenomics as a tool for understanding responses to pollutants in organisms: Using Atlantic cod (Gadus morhua) and a systems biology approach to environmental toxicology.
  • 2016. Integrative -omics analyses reveal perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) exposed to the persistent organic pollutant PCB 153.
  • 2016. Chemical warfare in the marine environment: genomic survey of the Atlantic cod (Gadus morhua) defensome reveals the absence of an important xenosensor.
  • 2014. ALTERATIONS IN THE HEPATIC PROTEOME OF POLAR COD (BOREOGADUS SAIDA) AFTER DIETARY EXPOSURE TO BENZO[A]PYRENE.
  • 2011. Genome-wide gene expression and proteome analysis of cod (Gadus morhua) liver after treatment with methylmecury and PCB153.
  • 2003. The expression of the surface associated MopE protein of Methylococcus capsulatus (Bath) is regulated by the concentration of copper in the growth medium.
  • 2003. Proteome studies on the methanotrophic bacterium Methylococcus capsulatus (Bath).
  • 2003. Multiple polypeptide forms observed in twodimensional gels of Methylococcus capsulatus (Bath)polypeptides are generated during the separation procedure.
  • 2002. Initial proteome studies of Methylococcus capsulatus (Bath).
Thesis at a second degree level
  • 2005. A study of McHr – a novel prokaryotic hemerythrin from Methylococcus capsulatus (Bath).
  • 2004. Studies of Methylococcus capsulatus (Bath): The surface associated protein SapE.
  • 2001. The proteome of Methylococcus capsulatus; An initial study by two-domentional gel electrophoresis.
Feature article
  • 2018. Torsken manglar eit viktig gen i forsvaret mot miljøgifter. Forskning.no.
Doctoral dissertation
  • 2019. Molecular characterization of key components of the adaptive immune system in ballan wrasse (Labrus bergylta).
  • 2005. Molecular analyses of copper responding proteins in Methylococcus capsulatus (Bath).
Abstract
  • 2012. Integrative environmental genomics of cod (Gadus morhua) reveal the mechanisms underlying MeHg- and PCB153 induced toxicity. Comparative Biochemistry and Physiology A. S49-S49.
  • 2010. iCod: Integrative environmental genomics of cod (Gadus morhua); the proteomics approach. Comparative Biochemistry and Physiology A. S44-S44.
  • 2010. The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation. The FEBS Journal. 185-185.
  • 2010. Human Naa50p (Nat5/San) displays both protein N-alpha- and N-epsilon-Acetyltransferase activity. The FEBS Journal. 182-182.
Poster
  • 2019. dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR.
  • 2019. THE CHEMICAL DEFENSOME OF ATLANTIC COD (GADUS MORHUA): HOW DOES IT DIFFER FROM DEFENSOME NETWORKS IN OTHER TELEOST SPECIES?
  • 2019. Polycyclic aromatic hydrocarbons potentiate vitamin D receptor (Vdr) activation by calcitriol in Atlantic cod (Gadus morhua).
  • 2019. In vitro assessment of estrogenic effects of bisphenols on Atlantic cod (Gadus morhua).
  • 2019. Evaluation of estrogenic effects of bisphenols using luciferase reporter assay and Atlantic cod (Gadus morhua) liver slice culture.
  • 2019. Chemical warfare in the aquatic environment - The chemical defensome networks of model fish species.
  • 2019. Biological responses of Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons (PAHs) and perfluoroalkyl substances (PFASs) .
  • 2019. Assessment of produced water toxicity using in vitro tools developed from Atlantic cod (Gadus morhua).
  • 2018. PW-Exposed: Produced water fractionation and advanced chemical and toxicological characterization using sensitive life stages of marine fish species.
  • 2018. MODELLING THE CHEMICAL DEFENSOME NETWORKS - a comparative visualisation of the defense genes and interactions in two fish species and human.
  • 2018. Establishing a cell-free method for xenobiotic detection using ligand activated receptors from the Atlantic cod (Gadus morhua).
  • 2018. Effects of perfluorinated compounds on Atlantic cod (Gadus morhua) PPARαa and PPARαb nuclear receptors.
  • 2017. dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua).
  • 2017. dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua) - WP8: biomarkers and xenosensors.
  • 2017. dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua) - WP8: biomarkers and xenosensors.
  • 2017. dCod 1.0 decoding the systems toxicology of Atlantic cod.
  • 2017. Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
  • 2017. Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
  • 2017. Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
  • 2017. Using precision cut liver slices (PCLS) for studying effects of environmental contaminants on the Atlantic cod (Gadus morhua) lipid metabolism.
  • 2017. Studying estrogenic effects of environmental pollutants by using the Atlantic cod (Gadus morhua) estrogen receptor α and a reporter gene assay.
  • 2017. Peroxisome proliferator-activated receptors (PPARs) as tools for studying effects of contaminants on the Atlantic cod (Gadus morhua) lipid metabolism.
  • 2017. Establishing a cell-free method for xenobiotic detection using ligand activated receptors from the Atlantic cod (Gadus morhua).
  • 2017. Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway .
  • 2017. Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway .
  • 2017. Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway .
  • 2016. Using precision-cut liver slices (PCLS) and luciferase reporter gene assay to characterize the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
  • 2016. Systems Toxicology Studies to Investigate Mechanisms of Toxicity of Environmental Chemicals Using Atlantic cod (Gadus morhua) as a Model Organism.
  • 2016. Peroxisome proliferator-activated receptors (PPARs) as tools to study effects of contaminants on the Atlantic cod (Gadus morhua) lipid metabolism.
  • 2016. Integrated analysis of transcriptome and proteome reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with the persistent organic pollutant PCB 153 .
  • 2016. Effektar på lipidmetabolismen til atlanterhavstorsk (Gadus morhua) etter eksponering mot enkeltsambindingar og blandingar av miljøgiftar.
  • 2014. Alterations in the hepatic proteome of polar cod (Boreogadus saida) after dietary exposure to benzo(a)pyrene .
  • 2012. Integrative environmental genomics of Atlantic cod (Gadus morhua): exposure of cod liver slices to environmental contaminants.
  • 2010. Human Naa50p (Nat5/San) Displays Both Protein Na-and Ne-Acetyltransferase activity.
  • 2004. Surface proteins of M. capsulatus (Bath) possibly involved in copper uptake.
  • 2004. Copper-regulation of some surface-exposed and secreted proteins of the methane-oxidizing bacterium Methylococcus capsulatus (Bath).
  • 2004. Copper homeostasis in Methylococcus capsulatus.
  • 2004. An introduction to copper homeostasis in Methylococcus capsulatus.
  • 2003. Identification of the ORF upstream of MopE in Methylococcus capsulatus.
  • 2003. Differential expression in sMMO and pMMO producing cells of Methylococcus capsulatus (Bath).
  • 2002. Initial proteome studies on Methylococcus capsulatus (Bath).
  • 2002. Characterization of copper-repressible extracellular protein of Methylococcus capsulatus (Bath).
Academic literature review
  • 2011. The copper responding surfaceome of Methylococccus capsulatus Bath. 97-104.
  • 2011. Methylococcus capsulatus (Bath): From Genome to Protein Function, and Vice Versa. 63-79.
  • 2011. METHANOTROPH OUTER MEMBRANE PREPARATION. 167-176.

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