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Oddmund Søvik's picture

Oddmund Søvik

Adjunct Professor
  • E-mailOddmund.Sovik@uib.no
  • Phone+47 55 97 52 47
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • 2017. The HNF1A mutant Ala180Val: Clinical challenges in determining causality of a rare HNF1A variant in familial diabetes. Diabetes Research and Clinical Practice. 142-149.
  • 2017. Targeted next-generation sequencing reveals MODY in up to 6.5% of antibody-negative diabetes cases listed in the Norwegian Childhood Diabetes Registry. Diabetologia. 625-635.
  • 2015. Glycogenin-2 is dispensable for liver glycogen synthesis and glucagon-stimulated glucose release. Journal of Clinical Endocrinology and Metabolism. E767-E775.
  • 2014. GCK-MODY diabetes as a protein misfolding disease: The mutation R275C promotes protein misfolding, self-association and cellular degradation. Molecular and Cellular Endocrinology. 55-65.
  • 2013. SUMOylation of pancreatic glucokinase regulates its cellular stability and activity. Journal of Biological Chemistry. 5951-5962.
  • 2013. Prevalence of monogenic diabetes in the population-based Norwegian Childhood Diabetes Registry. Diabetologia. 1512-1519.
  • 2013. Monogenetic diabetes mellitus in Norway :. Norsk Epidemiologi. 55-60.
  • 2013. Lessons from the Hvidoere International Study Group on childhood diabetes: be dogmatic about outcome and flexible in approach. Pediatric Diabetes. 473-480.
  • 2012. HNF1B mutation in a Turkish child with renal and exocrine pancreas insufficiency, diabetes and liver disease. Pediatric Diabetes. e1-e5.
  • 2012. GCK-MODY diabetes associated with protein misfolding, cellular self-association and degradation. Biochimica et Biophysica Acta - Molecular Basis of Disease. 1705-1715.
  • 2012. Familial occurrence of neonatal diabetes with duplications in chromosome 6q24: treatment with sulfonylurea and 40-yr follow-up. Pediatric Diabetes. 155-162.
  • 2011. Binding of ATP at the active site of human pancreatic glucokinase - nucleotide-induced conformational changes with possible implications for its kinetic cooperativity. The FEBS Journal. 2372-2386.
  • 2010. Fear of hypoglycaemia in mothers and fathers of children with Type 1 diabetes is associated with poor glycaemic control and parental emotional distress: a population-based study. Diabetic Medicine. 72-78.
  • 2010. DNA hypomethylation, transient neonatal diabetes, and prune belly sequence in one of two identical twins. European Journal of Pediatrics. 207-213.
  • 2009. The spectrum of ABCC8 mutations in Norwegian patients with congenital hyperinsulinism of infancy. Clinical Genetics. 440-448.
  • 2009. Mutasjonsdiagnostikk ved syndromer knyttet til RAS/MAPK-signalveien. Tidsskrift for Den norske legeforening. 2358-2361.
  • 2008. Wolcott-Rallison syndrome with 3-hydroxydicarboxylic aciduria and lethal outcome. Journal of Inherited Metabolic Disease.
  • 2008. Utredning og behandling av medfødt hyperinsulinisme (2): Diagnostiske og terapeutiske aspekter. Pediatrisk Endokrinologi. 56-63.
  • 2008. Utredning og behandling av medfødt hyperinsulinisme (1): Molekylære og genetiske aspekter. Pediatrisk Endokrinologi. 37-43.
  • 2008. Prevalence of HNF1A (MODY3) mutations in a Norwegian population (the HUNT2 Study). Diabetic Medicine. 775-781.
  • 2008. Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes. Diabetes. 1131-1135.
  • 2008. Lack of pancreatic body and tail in HNF1B mutation carriers. Diabetic Medicine. 782-787.
  • 2008. Diagnostic screening of MODY2/GCK mutations in the Norwegian MODY Registry. Pediatric Diabetes. 442-449.
  • 2008. Co-occurrence of vitamin D-dependent rickets type 1 and phenylketonuria. Acta Paediatrica. 665-667.
  • 2008. Catalytic activation of human glucokinase by substrate binding - residue contacts involved in the binding of D-glucose to the super-open form and conformational transitions. The FEBS Journal. 2467-2481.
  • 2007. Studies in 3,523 Norwegians and meta-analysis in 11,571 subjects indicate that variants in the hepatocyte nuclear factor 4 alpha (HNF4A) P2 region are associated with type 2 diabetes in Scandinavians. Diabetes. 3112-3117.
  • 2007. Spatiotemporal trends and age-period-cohort modeling of the incidence of type 1 diabetes among children aged < 15 years in Norway 1973-1982 and 1989-2003. Diabetes Care. 884-889.
  • 2007. Pancreatic lipomatosis is a structural marker in nondiabetic children with mutations in carboxyl-Ester lipase. Diabetes. 444-449.
  • 2007. Management of neonatal and infancy-onset diabetes mellitus. Endocrine Development. 94-105.
  • 2007. Diagnose og behandling av monogene former for nyfødt- og spebarnsdiabetes. Pediatrisk Endokrinologi. 23-28.
  • 2007. De novo HRAS and KRAS mutations in two siblings with short stature and neuro-cardio-facio-cutaneous features. Journal of Medical Genetics. 6 pages.
  • 2007. Allosteric activation of human glucokinase by free polyubiquitin chains and its ubiquitin-dependent cotranslational proteasomal degradation. Journal of Biological Chemistry. 22757-22764.
  • 2006. The impact of continuous subcutaneous insulin infusion on health-related quality of life in children and adolescents with type 1 diabetes. Acta Paediatrica. 1481-1487.
  • 2006. Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations. New England Journal of Medicine. 467-477.
  • 2006. Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction. Nature Genetics. 54-62.
  • 2006. From clinicogenetic studies of maturity-onset diabetes of the young to unraveling complex mechanisms of glucokinase regulation. Diabetes. 1713-1722.
  • 2006. A hepatocyte nuclear factor-4 alpha gene (HNF4A) P2 promoter haplotype linked with late-onset diabetes - Studies of HNF4A variants in the Norwegian MODY registry. Diabetes. 1899-1903.
  • 2005. Væskebehandling og risiko for hjerneødem hos barn med diabetiskketoacidose. Tidsskrift for Den norske legeforening. 2932-2935.
  • 2005. Preserved insulin response to tolbutamide in hepatocyte nuclear factor-1 alpha mutation carriers. Diabetic Medicine. 406-409.
  • 2005. Molekylærgenetisk diagnostikk ved diabetes mellitus. Tidsskrift for Den norske legeforening. 2968-2972.
  • 2005. Health-related quality of life and metabolic control in adolescents with diabetes: the role of parental care, control and involvement. Journal of Pediatric Nursing : Nursing Care of Children and Families. 373-82.
  • 2005. Evaluation of a program of group visits and computer-assisted consultations in the treatment of adolescents with Type 1 diabetes. Diabetic Medicine. 1522-9.
  • 2005. Diagnostic screening of NEUROD1 (MODY6) in subjects with MODY or gestational diabetes mellitus. Diabetic Medicine. 1012-1015.
  • 2004. The Coping Styles of Adolescents with Type 1 Diabetes areAssociated with Degree of Metabolic Control. Diabetes Care. 1313-1317.
  • 2003. [Intravenous Enzyme Substitution Therapy in Children With Fabry's Disease] . Tidsskrift for Den norske legeforening.
  • 2003. Permanent neonatal diabetes caused by glucokinase deficiency; inborn error of the glucose-insulin signaling pathway. Diabetes. 2854-2860.
  • 2003. Measuring self-reported, health-related, quality of life in adolescents with type 1 diabetes using both generic and disease-specific instruments. Acta Paediatrica. 1190-1196.
  • 2003. Intravenøs enzymsubstitusjons-behandling ved Fabry sykdom hos barn. Tidsskrift for Den norske legeforening. 3338-3390.
  • 2001. N EONATAL D IABETES M ELLITUS D UE TO C OMPLETE G LUCOKINASE D EFICIENCY. New England Journal of Medicine. 1588-1592.
  • 2000. MODY associated with two novel hepatocyte nuclear factor 1 alpha loss of function mutations. Biochemical and Biophysical Research Communications - BBRC. 792-798.
  • 2000. A simple test for the hot spot mutation P291fsinsC in MODY3. Diabetologia. 818-819.
Academic lecture
  • 2004. Health-related quality of life in adolescents with type 1 diabetes.
  • 2002. Functional health status and wellbeing in adolescents with type 1 diabetes – a 15 months intervention study.
  • 1999. Quality of life and metabolic control among adolecents with diabetes in western Norway.
  • 1999. Livskvalitet og metabolsk kontroll hos unge med diabetes.
Academic chapter/article/Conference paper
  • 2008. MODY5 due to mutations in TCF2 (HNF-1ß): The clinical spectrum with special reference to urogenital malformations. 7 pages.
  • 2005. Diagnosis and mangement of MODY in a pediatric setting. 10 pages.
Poster
  • 2005. Evaluering av et tverrfaglig poliklinisk oppfølgingstilbud til ungdom med type 1 diabetes og deres foreldre.
  • 2002. Experiences with an educational and psychosocial intervention program designed for adolescents with type 1 diabetes and their parents.
  • 2002. Adolescents with type 1 diabetes - experiences with an outpatient intervention program.
  • 2001. A population based study of functional health status and well being in adolescents with type 1 diabetes.
  • 2000. Quality of life in adolescents with type 1 diabetes; differences according to gender.
  • 2000. Adolescents with type 1 diabetes and quality of life.
Academic literature review
  • 2010. Fremskritt innen diabetesgenetikk. 1145-1149.

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