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Olayiwola Adekoya's picture

Olayiwola Adekoya

Assistant Professor
  • E-mailOlayiwola.Adekoya@uib.no
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • Sylte, Ingebrigt; Dawadi, Rangita; Malla, Nabin; von Hofsten, Susannah; Nguyen, Tra-Mi; Solli, Ann Iren; Berg, Eli; Adekoya, Olayiwola; Svineng, Gunbjørg; Winberg, Jan-Olof. 2018. The selectivity of galardin and an azasugar-based hydroxamate compound for human Matrix metalloproteases and bacterial metalloproteases. PLOS ONE. 28 pages.
  • Sjøli, Stian; Nuti, Elisa; Camodeca, Caterina; Bilto, Irina; Rossello, Armando; Winberg, Jan-Olof; Sylte, Ingebrigt; Adekoya, Olayiwola. 2016. Synthesis, experimental evaluation and molecular modelling of hydroxamate derivatives as zinc metalloproteinase inhibitors. European Journal of Medicinal Chemistry. 141-153.
  • Singh, Tanya; Adekoya, Olayiwola; Jayaram, B. 2015. Understanding the binding of inhibitors of matrix metalloproteinases by molecular docking, quantum mechanical calculations, molecular dynamics simulations, and a MMGBSA/MMBappl study. Molecular Biosystems. 1041-1051.
  • Odunuga, Odutayo O.; Adekoya, Olayiwola; Sylte, Ingebrigt. 2015. High-level expression of pseudolysin, the extracellular elastase of Pseudomonas aeruginosa, in Escherichia coli and its purification. Protein Expression and Purification. 79-84.
  • Jantan, Ibrahim; Bukhari, Syed Nasir Abbas; Adekoya, Olayiwola; Sylte, Ingebrigt. 2014. Studies of synthetic chalcone derivatives as potential inhibitors of secretory phospholipase A<sub>2</sub>, cyclooxygenases, lipoxygenase and pro-inflammatory cytokines. Drug Design, Development and Therapy. 1405-1418.
  • Adekoya, Olayiwola; Sjøli, Stian; Wushur, Imin; Bilto, Irina; Marques, Sergio M; Santos, M Amelia; Nuti, Elisa; Cercignani, Giovanni; Rossello, Armando; Winberg, Jan-Olof; Sylte, Ingebrigt. 2014. Inhibition of pseudolysin and thermolysin by hydroxamate-based MMP inhibitors. European Journal of Medicinal Chemistry. 340-348.
  • Volti, Giovanni Li; Galvano, Fabio; Frigiola, Alessandro; Guccione, Salvatore; Di Giacomo, Claudia; Forte, Stefano; Tringali, Giovanni; Caruso, Massimo; Adekoya, Olayiwola; Gazzolo, Diego. 2010. Potential immunoregulatory role of heme oxygenase-1 in human milk: a combined biochemical and molecular modeling approach. Journal of Nutritional Biochemistry. 865-871.
  • Okeke, Malachy Ifeanyi; Adekoya, Olayiwola; Moens, Ugo; Tryland, Morten; Traavik, Terje; Nilssen, Øivind. 2009. Comparative sequence analysis of A-type inclusion (ATI) and P4c proteins of orthopoxviruses that produce typical and atypical ATI phenotypes. Virus genes. 200-209.
  • Gani, Osman A.B.S.M.; Adekoya, Olayiwola; Giurato, L; Spyrakis, F; Cozzini, P; Guccione, S; Winberg, Jan-Olof; Sylte, Ingebrigt. 2008. Theoretical calculations of the catalytic triad in short-chain alcohol dehydrogenases/reductases. Biophysical Journal.
  • Adekoya, Olayiwola; Willassen, Nils Peder; Sylte, Ingebrigt. 2006. Molecular insight into pseudolysin inhibition using the MM-PBSA and LIE methods. Journal of Structural Biology. 129-144.
  • Adekoya, Olayiwola; Helland, Ronny; Willassen, Nils P; Sylte, Ingebrigt. 2006. Comparative sequence and structure analysis reveal features of cold adaptation of an enzyme in the thermolysin family. Proteins: Structure, Function, and Bioinformatics.
  • Adekoya, Olayiwola Adedotun; Willassen, Nils Peder; Sylte, Ingebrigt. 2005. The protein-protein interactions between SMPI and thermolysin studied by molecular dynamics and MM/PBSA calculations. Journal of Biomolecular Structure and Dynamics. 521-532.
Academic chapter/article/Conference paper
  • Sylte, Ingebrigt; Adekoya, Olayiwola. 2013. Thermolsyin. 9 pages.
Abstract
  • Tarpley, Reid S.; Adekoya, Olayiwola; Sylte, Ingebrigt; Odunuga, Odutayo O. 2013. Large-scale expression and purification of active pseudolysin in Escherichia coli. The FASEB Journal. 1 pages.
  • Adekoya, Olayiwola; Sylte, Ingebrigt. 2011. Molecular interactions of ABT and matrix metalloproteinases. The FEBS Journal. 322-322.
  • Sjøli, Stian; Adekoya, Olayiwola; Jiang, Yang; Akselsen, O; Hansen, VT; Svineng, Gunbjørg; Sylte, Ingebrigt; Winberg, Jan-Olof. 2010. Novel Inhibitors of Matrix Metalloprotease-9 and-14. The FEBS Journal. 265-265.
Poster
  • Okeke, malachy ifeanyi; Adekoya, Olayiwola; Traavik, Terje; Nilssen, Øivind. 2007. Comparative sequence and structure analysis of A-tpe inclusion body (ATI) and p4c proteins of Orthopoxviruses that produce typical and atypical ATI phenotypes.
  • Ghani, Osman A.b.s.m; Adekoya, Olayiwola; Giuratob, L; Guccione, S; Winberg, Jan-Olof; Sylte, Ingebrigt. 2005. The catalytic mechanisms of short-chain dehydrogenases/ reductases.
  • Ghani, Osman A.b.s.m; Adekoya, Olayiwola; Giuratob, L; Guccione, S; Winberg, Jan-Olof; Sylte, Ingebrigt. 2005. The catalytic mechanisms of short-chain dehydrogenases/ reductases.
  • Adekoya, Olayiwola Adedotun; Helland, Ronny; Willassen, Nils Peder; Sylte, Ingebrigt. 2005. Structural determinants for a cold adapted enzyme in the thermolysin family.
  • Helland, Ronny; Adekoya, Olayiwola; Mekonnen, Seble Merid; Gjellesvik, Dag Rune; Edvardsen, Øyvind; Høgda, Kjell Arild; Grøttum, Karl Johan; Sylte, Ingebrigt; Smalås, Arne Oskar; Willassen, Nils Peder. 2002. Determination of Molecular Descriptors from Analysis of Sequence and Genome Data.
  • Helland, Ronny; Adekoya, Olayiwola; Mekonnen, Seble Merid; Gjellesvik, Dag Rune; Edvardsen, Øyvind; Høgda, Kjell Arild; Grøttum, Karl Johan; Sylte, Ingebrigt; Smalås, Arne Oskar; Willassen, Nils Peder. 2001. Determination of Molecular Descriptors from Analysis of Sequence and Genome Data.
Academic literature review
  • Adekoya, Olayiwola; Sylte, Ingebrigt. 2009. The Thermolysin Family (M4) of Enzymes: Therapeutic and Biotechnological Potential. 7-16.

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