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Ole Bernt Fasmer's picture

Ole Bernt Fasmer

Professor, in adult psychiatry
  • E-mailOle.Fasmer@uib.no
  • Phone+47 55 95 86 55+47 415 50 327
  • Visitor Address
    Sandviken Hospital
    5035 Bergen
  • Postal Address
    Postboks 7804
    5020 Bergen

Biological aspects of bipolar disorder and ADHD, in particular comorbidity with somatic disorders. Mathematical analyses of time series (motor activity and heart rate).

Teaches clinical psychiatry for medical students.

Textbook
  • 2012. Bipolare lidelser. Fagbokforlaget.
Academic article
  • 2019. Individual Variability in Reaction Time and Prediction of Clinical Response to Methylphenidate in Adult ADHD: A Prospective Open Label Study Using Conners’ Continuous Performance Test II. Journal of Attention Disorders. 1-15.
  • 2019. Cyclothymic temperament: Associations with ADHD, other psychopathology, and medical morbidity in the general population. Journal of Affective Disorders. 447 pages.
  • 2019. A psychophysiological investigation of the interplay between orienting and executive control during stimulus conflict: A heart rate variability study. Physiology and Behavior. 1-8.
  • 2018. Motor activity patterns in acute schizophrenia and other psychotic disorders can be differentiated from bipolar mania and unipolar depression. Psychiatry Research. 418-425.
  • 2018. Motor activity based classification of depression in unipolar and bipolar patients. IEEE International Symposium on Computer-Based Medical Systems. 316-321.
  • 2018. Graph theory applied to the analysis of motor activity in patients with schizophrenia and depression. PLOS ONE. 1-19.
  • 2018. Diabetes is associated with decreased migraine risk: A nationwide cohort study. Cephalalgia. 1759-1764.
  • 2018. Actigraphy as an objective intra‑individual marker of activity patterns in acute‑phase bipolar disorder: a case series. International journal of bipolar disorders.
  • 2017. Variability of activity patterns across mood disorders and time of day. BMC Psychiatry.
  • 2017. Do medical students and young physicians assess reliably their self-efficacy regarding communication skills? A prospective study from end of medical school until end of internship. BMC Medical Education.
  • 2017. A pilot study to determine whether combinations of objectively measured activity parameters can be used to differentiate between mixed states, mania, and bipolar depression. International journal of bipolar disorders. 1-8.
  • 2016. Patterns of motor activity in spontaneously hypertensive rats compared to Wistar Kyoto rats. Behavioral and Brain Functions. 1-13.
  • 2016. Mood and motor activity in euthymic bipolar disorder with sleep disturbance. Journal of Affective Disorders. 23-31.
  • 2016. Linear and non-linear analyses of Conner's Continuous Performance Test-II discriminate adult patients with attention deficit hyperactivity disorder from patients with mood and anxiety disorders. BMC Psychiatry. 10 pages.
  • 2016. Distribution of active and resting periods in the motor activity of patients with depression and schizophrenia. Psychiatry Investigation. 112-120.
  • 2016. Circadian rest-activity rhythms during benzodiazepine tapering covered by melatonin versus placebo add-on: Data derived from a randomized clinical trial. BMC Psychiatry. 1-8.
  • 2016. Blue-blocking glasses as additive treatment for mania: A randomized placebo-controlled trial. Bipolar Disorders. 221-232.
  • 2016. An ISBD perspective on the sociocultural challenges of managing bipolar disorder: A content analysis. Australian and New Zealand journal of psychiatry (Print). 1096-1103.
  • 2016. Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review. Journal of Attention Disorders. 203-228.
  • 2015. Prevalence and clinical features associated to bipolar disorder-migraine comorbidity: A systematic review. Comprehensive Psychiatry. 1-16.
  • 2015. On the role of NOS1 ex1f-VNTR in ADHD-allelic, subgroup, and meta-analysis. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 445-458.
  • 2015. Motor Activity in Adult Patients with Attention Deficit Hyperactivity Disorder. Psychiatry Investigation. 474-482.
  • 2015. Genome wide association study identifies variants in NBEA associated with migraine in bipolar disorder . Journal of Affective Disorders. 453-461.
  • 2015. Effect of acupuncture at HT7 on heart rate variability: An exploratory study. Acupuncture in Medicine. 30-35.
  • 2015. Can we rely on simulated patients' satisfaction with their consultation for assessing medical students' communication skills? A cross-sectional study. BMC Medical Education. 6 pages.
  • 2015. Actigraphically assessed activity in unipolar depression: A comparison of inpatients with and without motor retardation. Journal of Clinical Psychiatry. 1181-1187.
  • 2014. Holdninger til bruk av medisiner hos voksne med ADHD målt ved hjelp av Beliefs about Medicines Questionnaire (BMQ). Tidsskrift for Norsk Psykologforening. 119-121.
  • 2014. Blocking blue light during mania - markedly increased regularity of sleep and rapid improvement of symptoms: A case report. Bipolar Disorders. 894-898.
  • 2014. Attention deficit hyperactivity disorder among inmates in Bergen Prison. Scandinavian Journal of Psychology. 343-349.
  • 2014. Actigraphic assessment of motor activity in acutely admitted inpatients with bipolar disorder. PLOS ONE. 9 pages.
  • 2013. The influence of glutamatergic antagonism on motor variability, and comparison to findings in schizophrenia patients. Acta Neuropsychiatrica. 105-112.
  • 2013. Does diabetes have a protective effect on migraine? Epidemiology. 129-134.
  • 2012. The impact of cyclothymic temperament in adult ADHD. Journal of Affective Disorders. 241-247.
  • 2012. Risk of depression in diabetes is highest for young persons using oral anti-diabetic agents. Diabetic Medicine. 509-514.
  • 2012. Comorbidity of Migraine With ADHD. Journal of Attention Disorders. 339-345.
  • 2012. Co-prescription of medication for bipolar disorder and diabetes mellitus: A nationwide population-based study. BMC Medicine. 6 pages.
  • 2011. Nonlinear analysis of motor activity shows differences between schizophrenia and depression: a study using Fourier analysis and sample entropy. PLOS ONE. 10 pages.
  • 2011. No association between the serotonin transporter gene polymorphism 5-HTTLPR and cyclothymic temperament as measured by TEMPS-A. Journal of Affective Disorders. 308-312.
  • 2011. DIRAS2 is Associated with Adult ADHD, Related Traits, and Co-Morbid Disorders. Neuropsychopharmacology. 2318-2327.
  • 2011. Comorbidity of Asthma With ADHD. Journal of Attention Disorders. 564-571.
  • 2011. Bipolar disorder risk alleles in adult ADHD patients. Genes, Brain and Behavior. 418-423.
  • 2011. Are Migraine and Bipolar Disorders Comorbid Phenomena? Findings From a Pharmacoepidemiological Study Using the Norwegian Prescription Database. Journal of Clinical Psychopharmacology. 734-739.
  • 2011. Adult attention deficit hyperactivity disorder is associated with migraine headaches. European Archives of Psychiatry and Clinical Neuroscience. 595-602.
  • 2011. Adult attention deficit hyperactivity disorder is associated with asthma. BMC Psychiatry. 7 pages.
  • 2011. A pharmaco-epidemiological study of migraine and antidepressant medications: Complete one year data from the Norwegian population. Journal of Affective Disorders. 198-204.
  • 2010. Multicenter analysis of the SLC6A3/DAT1 VNTR haplotype in persistent ADHD suggests differential involvement of the gene in childhood and persistent ADHD. Neuropsychopharmacology. 656-664.
  • 2010. Meta-analysis of brain-derived neurotrophic factor p.Val66Met in adult ADHD in four European populations. American Journal of Medical Genetics. 512-523.
  • 2010. Bipolar symptoms in adult attention-deficit/hyperactivity disorder: A cross-sectional study of 510 clinically diagnosed patients and 417 population-based controls. Journal of Clinical Psychiatry. 48-57.
  • 2010. A genome-wide linkage study of bipolar disorder and co-morbid migraine: Replication of migraine linkage on chromosome 4q24, and suggestion of an overlapping susceptibility region for both disorders on chromosome 20p11. Journal of Affective Disorders. 14-26.
  • 2010. A genome-wide association study of bipolar disorder and comorbid migraine. Genes, Brain and Behavior. 673-680.
  • 2009. The relationship of bulimia and anorexia nervosa with bipolar disorder and its temperamental foundations. Journal of Affective Disorders. 309-314.
  • 2009. Occupational outcome in adult ADHD:impact of symptom profile, comorbid psychiatric problems, and treatment: a cross-sectional study of 414 clinically diagnosed adult ADHD patients. Journal of Attention Disorders. 175-187.
  • 2009. Multicenter analysis of the SLC6A3/DAT1 VNTR haplotype in persistent ADHD suggests differential involvement of the gene in childhood and persistent ADHD. Neuropsychopharmacology. 656-664.
  • 2009. Migraine in affectively ill Mexican adolescents. World Psychiatry. 37-39.
  • 2009. Is a Family History of Bipolar Disorder a Risk Factor for Migraine among Affectively Ill Patients? Psychopathology. 119-123.
  • 2009. Do physicians improve their communication skills between finishing medical school and completing internship? A nationwide prospective observational cohort study. Patient Education and Counseling. 207-212.
  • 2009. Clinical and pathophysiological relations between migraine and mood disorders. Current Psychiatry Reviews. 93-109.
  • 2009. A study of age at onset and affective temperaments in a Norwegian sample of patients with mood disorders. Journal of Affective Disorders. 229-233.
  • 2008. Non-right-handedness is assosiated with migraine and soft bipolarity in patients with mood disorders. Journal of Affective Disorders. 217-224.
  • 2008. Medical students' cognitive and affective attitudes towards learning and using communication skills - a nationwide cross-sectional study. Medical Teacher. 272-279.
  • 2008. Genetic Analyses of Dopamine Related Genes in Adult ADHD Patients Suggest an Association With the DRD5-Microsatellite Repeat, But Not With DRD4 or SLC6A3 VNTRs. American Journal of Medical Genetics. 1470-1475.
  • 2008. Dissociative experiences differentiate bipolar-II from unipolar depressed patients: The mediating role of cyclothymia and the Type A behaviour speed and impatience subscale. Journal of Affective Disorders. 207-216.
  • 2007. Observed communication skills: how do they relate to the consultation content? A nation-wide study of graduate medical students seeing a standardized patient for a first-time consultation in a general practice setting. BMC Medical Education. 43.
  • 2007. Observed Communication Skills: How Do They Relate To The Consultation Content?A nation-wide study of graduate medical students seeing a standardized patient for afirst-time consultation in a general practice setting. BMC Medical Education.
  • 2007. Curriculum factors influencing knowledge of communication skills among medical students. BMC Medical Education.
  • 2007. Assessing medical students' attitudes toward learning communication skills- which components of attitudes do we measure? BMC Medical Education. 7 pages.
  • 2006. Type A behaviour differentiates bipolar II from unipolar depressed patients. Journal of Affective Disorders. 7-13.
  • 2006. Migraine with and without aura: association with depression and anxiety disorder in a population-based study. The HUNT Study. Cephalalgia. 1-6.
  • 2005. Migraine aura without headache compared to migraine with aura in patients with affective disorders. The Journal of Headache and Pain. 378-386.
  • 2005. Is migraine in unipolar depressed patients a bipolar spectrum trait? Journal of Affective Disorders. 233-242.
  • 2005. Does change from a traditional to a new medical curriculum reduce negative attitudes among students? A quasi-experimental study. Medical Teacher. 737-739.
  • 2005. Does change from a traditional to a new medical curriculum reduce negative attitudes among students? A quasi-experimental study. Medical Teacher. 737-739.
  • 2005. Bipolar II and migraine - interrelated disorders with a possible common treatment. Aspects of affection. 60-63.
  • 2004. Migrene og psykiske lidelser. Tidsskrift for Den norske legeforening. 2350-2353.
  • 2003. Undervisning i klinisk kommunikasjon for medisinstudenter i Norge. Tidsskrift for Den norske legeforening. 2277-2280.
  • 2002. Laterality of pain in migraine with comorbid unipolar depressive and bipolar II disorders. Bipolar Disorders. 290-295.
  • 2002. Are Migraines and Bipolar Disorder Related ? The Psychiatric Times. 48-51.
  • 2001. The prevalence of migraine in patients with bipolar and unipolar affective disorders. Cephalalgia. 894-899.
  • 2001. Clinical characteristics of patients with major affective disorders and comorbid migraine. The World Journal of Biological Psychiatry. 149-155.
Academic lecture
  • 2017. Actigraphic assessment of motor activity in acutely admitted inpatients with bipolar disorder.
  • 2007. Does the internship period improve clinical communication skills.
  • 2007. Communication skills and job stress during medical internship.
  • 2006. Development of communication skills through medical school.
  • 2005. Factors influencing knowledge of communication skills in medical school.
  • 2003. Bipolar disorder II and Migraine.
  • 2001. Clinical characteristics of patients with affective temperaments and major affective disorders.
Non-fiction book
  • 1991. Biologisk psykiatri. Alma Mater.
Popular scientific article
  • 2013. ADHD og astma. BestPractice. 22-24.
Feature article
  • 2013. Antidepressive legemidler – klinisk praksis må endres. Tidsskrift for Den norske legeforening. 428-430.
Letter to the editor
  • 2016. Distribution and Characteristics of Active and Inactive Periods Distinguish Unipolar Depression With and Without Motor Retardation. Journal of Clinical Psychiatry.
Doctoral dissertation
  • 1988. The involvement of serotonergic systems in the regulation of nociception in mice.
Academic chapter/article/Conference paper
  • 2018. Depresjon: a motor activity database of depression episodes in unipolar and bipolar patients. 6 pages.
  • 2012. Migrene og bipolare lidelser. 14 pages.
  • 2012. Historisk utvikling, epidemiologi og klassifikasjon av bipolare lidelser. 32 pages.
  • 2012. Det bipolar spektrum. 23 pages.
  • 2012. Affektive temperamenter og personlighet ved bipolare lidelser. 22 pages.
  • 2012. ADHD og bipolar lidelse. 14 pages.
  • 2005. Co-morbidity of migraine and affective disorders. 16 pages.
  • 1992. Modifications in nociceptive reactivity following various serotonergic treatments. Methodological difficulties. 16 pages.
Abstract
  • 2015. Actigraphy can identify differences in motor activity in acute episodes of mood disorders. Bipolar Disorders. 86-86.
  • 2013. Virtual darkness as additive treatment in mania - a randomized controlled trial. Bipolar Disorders. 60-60.
  • 2010. A genetic study of bipolar disorder and co-morbid migraine. Bipolar Disorders. 62-62.
  • 2008. Non-right handedness is associated with migraine and soft bipolar spectrum diagnoses. Bipolar Disorders. 4-4.
  • 2007. The complex relationship between migraine and psychiatry. European Neuropsychopharmacology. 133-134.
  • 2006. Vagal nerve stimulation in bipolar disorders. Bipolar Disorders. 11.
  • 2006. Reduced complexity of motor activity patterns in schizophrenia. Schizophrenia Research. 39-39.
  • 2004. Patterns of motor activity in schizophrenia and depression. European Neuropsychopharmacology. S375-S375.
Poster
  • 2019. Detecting and Predicting Mood Transitions in Bipolar Disorder - study protocol.
  • 2016. Socio- Cultural Challenges in the Management of Bipolar Disorder: A Trans- Cultural qualitative Study by the International Society of Bipolar Disorders (ISBD).
  • 2016. MOTOR ACTIVITY PATTERNS IN EUTHYMIC BIPOLAR PATIENTS WITH UNSTABLE REST-ACTIVITY CYCLES AND MOOD VARIABILITY RESEMBLE FINDINGS IN AFFECTIVE EPISODES.
  • 2015. Actigraphy can Identify Differences in Motor Activity in Acute Episodes of Mood Disorders.
  • 2014. Motor Activity in Acutely Admitted Inpatients with Bipolar Disorder.
  • 2014. Differences in Actigraphically Assessed Activity in Unipolar Depression between Inpatients with and without Motor Retardation.
  • 2006. Genetic Analysis of Candidate Genes in Adult ADHD Patients from Norway.
  • 2005. Vagus nerve stimulation in Major Depression and bipolar II disorders.
  • 2005. Objective registration of motor activity pattern in schizophrenia and depression.
  • 2005. Objective registration of motor activity pattern in schizophrenia and depression.
  • 2005. Objective registration of motor activity in schizophrenia.
  • 2005. Objective registration motor activity in schizophrenia.
  • 2005. Graduating medical students achieved level of clinical communication skills and its impact upon outcome.
  • 2005. A Nation-wide Bio-bank of blood samples from adult ADHD patients in Norway.
  • 2005. A Nation-wide Bio-bank of blood samples from adult ADHD patients in Norway.
  • 2001. Migrane anxiety and depression. A large population based study in Norway.
  • 2001. Migraine with aura increases suicide risk in patients with major affective disorders.
  • 2001. HUNT: Migraine, anxiety and depression. A large population-based study in Norway.
  • 2001. Clinical characteristics of patients with major affective disorders and comorbid migraine.
Academic literature review
  • 2010. Clinical assessment and diagnosis of adults with attention-deficit/hyperactivity disorder. 1569-1580.

More information in national current research information system (CRIStin)

 

Key publications:

 

Fasmer OB (2001). The prevalence of migraine in patients with bipolar and unipolar        affective disorders. Cephalalgia 21: 894 – 899.

 

Fasmer OB, Akiskal HS, Kelsoe JR, Oedegaard KJ (2009). Clinical and pathophysiological relations between migraine and mood disorders. Current Psychiatry Reviews 5 : 93 – 109.

 

Fasmer OB, Liao H, Huang Y, Berle JØ, Wu J, Oedegaard KJ, Wik G, Zhang Z. (2012).

A naturalistic study of the effect of acupuncture on heart-rate variability. J Acupunct Meridian Stud. 5 : 15-20.

 

Fasmer OB, Riise T, Lund A, Dilsaver SC, Hundal O, Oedegaard KJ. (2012). Comorbidity of migraine with ADHD. J Atten Disord. 16 :339 - 345.

 

Krane-Gartiser K, Henriksen TE, Morken G, Vaaler A, Fasmer OB (2014). Actigraphic assessment of motor activity in acutely admitted inpatients with bipolar disorder. PLoS One   9 :  e89574

Fields of competence