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Rakel Brendsdal Forthun's picture

Rakel Brendsdal Forthun

Staff Engineer
  • E-mailRakel.Forthun@uib.no
  • Phone+47 55 58 45 11+47 414 59 638
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
    Room 
    Armauer Hansens hus, rom 008
  • Postal Address
    Postboks 7804
    5020 Bergen

My main field of interest is proteomic analyses of novel therapeutic combinations for the treatment of Acute Myeloid Leukemia (AML). In this project, my main focus is to find new drugs and chemicals that can complement and increase the anti-leukemic effect of valproic acid, and to discover the mechanisms behind this effect.

Cross-species functional genomic analysis identifies resistance genes of the histone deacetylase inhibitor valproic acid.

Forthun RB, Sengupta T, Skjeldam HK, Lindvall JM, McCormack E, Gjertsen BT, Nilsen H.

PLoS One. 2012

 

Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia.

McCormack E, Haaland I, Venås G, Forthun RB, Huseby S, Gausdal G, Knappskog S, Micklem DR, Lorens JB, Bruserud O, Gjertsen BT.

Leukemia. 2012

 

Clinical proteomics of myeloid leukemia.

Hjelle SM, Forthun RB, Haaland I, Reikvam H, Sjøholt G, Bruserud O, Gjertsen BT.

Genome Med. 2010

 

 

• Master degree in medical cell biology, "A phosphoproteomic study of the Theophylline-Valproic acid-ATRA combination therapy in the BNML rat model" 2008

• PhD, "Phosphoproteomics in disease stratification and therapy design of acute myeloid leukemia", 2012