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Rolf Kristian Berge's picture

Rolf Kristian Berge

Professor
  • E-mailRolf.Berge@uib.no
  • Phone+47 55 97 30 98
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • 2014. Reduction of early sexual maturation in male SO Atlantic salmon (Salmo salar L.) by dietary supplementation of tetradecylthioacetic acid (TTA). Aquaculture Research. 922-933.
  • 2013. Tetradecylthioacetic Acid Increases Fat Metabolism and Improves Cardiac Function in Experimental Heart Failure. Lipids. 139-154.
  • 2013. Smooth muscle cells in human atherosclerosis: Proteomic profiling reveals differences in expression of Annexin A1 and mitochondrial proteins in carotid disease. Journal of Molecular and Cellular Cardiology. 65-72.
  • 2013. Krill oil versus fish oil in modulation of inflammation and lipid metabolism in mice transgenic for TNF-α. European Journal of Nutrition. 1315-1325.
  • 2013. Krill hydrolysate free amino acids responsible for feed intake stimulation in Atlantic salmon (Salmo salar). Aquaculture Nutrition. 47-61.
  • 2013. Induction of mitochondrial biogenesis and respiration is associated with mTOR regulation in hepatocytes of rats treated with the pan-PPAR activator tetradecylthioacetic acid (TTA). Biochemical and Biophysical Research Communications - BBRC. 573-578.
  • 2013. Fish Oil and the Pan-PPAR Agonist Tetradecylthioacetic Acid Affect the Amino Acid and Carnitine Metabolism in Rats. PLOS ONE. 9 pages.
  • 2013. Disturbed carnitine regulation in chronic heart failure - Increased plasma levels of palmitoyl-carnitine are associated with poor prognosis. International Journal of Cardiology. 1892-1899.
  • 2013. Dietary intake of n-3 long-chain polyunsaturated fatty acids and risk of myocardial infarction in coronary artery disease patients with or without diabetes mellitus: a prospective cohort study. BMC Medicine.
  • 2012. Omega-3 status and the relationship between plasma asymmetric dimethylarginine and risk of myocardial infarction in patients with suspected coronary artery disease. Cardiology Research and Practice. 11 pages.
  • 2012. Long-term treatment with the pan-PPAR agonist tetradecylthioacetic acid or fish oil is associated with increased cardiac content of n-3 fatty acids in rat. Lipids in Health and Disease. 11 pages.
  • 2012. Lipid-lowering effects of tetradecylthioacetic acid in antipsychotic-exposed, female rats: challenges with long-term treatment. PLOS ONE. 11 pages.
  • 2012. Krill powder increases liver lipid catabolism and reduces glucose mobilization in tumor necrosis factor-alpha transgenic mice fed a high-fat diet. Metabolism: Clinical and Experimental. 1461-1472.
  • 2012. Genome wide response to dietary tetradecylthioacetic acid supplementation in the heart of Atlantic Salmon (Salmo salar L). BMC Genomics. 13 pages.
  • 2012. Free carnitine and acylcarnitines in obese patients with polycystic ovary syndrome and effects of pioglitazone treatment. Fertility and Sterility. 1620-1626,e1.
  • 2012. Fish oil and 3-thia fatty acid have additive effects on lipid metabolism but antagonistic effects on oxidative damage when fed to rats for 50 weeks. Journal of Nutritional Biochemistry. 1384-1393.
  • 2012. Effects of local delivery of Tetradecylthioacetic acid within the injured coronary vessel wall. Scandinavian Cardiovascular Journal. 366-373.
  • 2012. Bioactive fatty acids reduce development of gastric cancer following duodenogastric reflux in rats. Surgical Science. 34-42.
  • 2011. Synthesis of novel PPARα/γ dual agonists as potential drugs for the treatment of the metabolic syndrome and diabetes type II designed using a new de novo design program protobuild. Organic and biomolecular chemistry. 1169-1188.
  • 2011. Salmon diet in patients with active ulcerative colitis reduced the simple clinical colitis activity index and increased the anti-infl ammatory fatty acid index – a pilot study. Scandinavian Journal of Clinical and Laboratory Investigation. 68-73.
  • 2010. Systemic Markers of Interferon-–Mediated Immune Activation and Long-Term Prognosis in Patients With Stable Coronary Artery Disease. Arteriosclerosis, Thrombosis and Vascular Biology.
  • 2010. Protein kinase A activators and the pan-PPAR agonist tetradecylthioacetic acid elicit synergistic anti-leukaemic effects in AML through CREB. Leukemia Research. 77-84.
  • 2010. Platelet activating factor stimulates arachidonic acid release in differentiated keratinocytes via arachidonyl non-selective phospholipase A(2). Archives of Dermatological Research. 221-227.
  • 2010. Novel phospholipid analogues of pan-PPAR activator tetradecylthioacetic acid are more PPARα selective. Bioorganic & Medicinal Chemistry Letters. 1252-1255 .
  • 2010. Effects of dietary lipid, vitamins and minerals on total amounts and redox status of glutathione and ubiquinone in tissues of Atlantic salmon (Salmo salar): a multivariate approach. British Journal of Nutrition. 980-988.
  • 2009. Trans-10, cis-12-conjugated linoleic acid reduces the hepatic triacylglycerol content and the leptin mRNA level in adipose tissue in obese Zucker fa/fa rats. British Journal of Nutrition. 803-815.
  • 2009. The absorption, distribution and biological effects of a modified fatty acid in its free form and as an ethyl ester in rats. Chemico-Biological Interactions. 227-232.
  • 2009. The absorption, distribution and biological effects of a modified fatty acid in its free form and as an ethyl ester in rats. Chemico-Biological Interactions. 227-232.
  • 2009. Tetradecylthioacetic acid attenuates dyslipidaemia in male patients with type 2 diabetes mellitus, possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidation. Diabetes, obesity and metabolism. 304-314.
  • 2009. Synthesis and Analysis of Novel Glycerolipids for the Treatment of Metabolic Syndrome. Journal of Medicinal Chemistry. 1172-1179.
  • 2009. Reduced sexual maturation in male post-smolt 1+ Atlantic salmon (Salmo salar L.) by dietary tetradecylthioacetic acid. Aquaculture Research. 533-541.
  • 2009. Increased survival by feeding tetradecylthioacetic acid during a natural outbreak of heart and skeletal muscle inflammation in S0 Atlantic salmon, Salmo salar L. Journal of Fish Diseases. 953-961.
  • 2009. Fatty Acid Incubation of Myotubes From Humans With Type 2 Diabetes Leads to Enhanced Release of β-Oxidation Products Because of Impaired Fatty Acid Oxidation. Diabetes. 527-535.
  • 2009. Different skeletal effects of the peroxisome proliferator activated receptor (PPAR)α agonist fenofibrate and the PPARγ agonist pioglitazone. BMC Endocrine Disorders. 13 pages.
  • 2009. Dietary supplementation of tetradecylthioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed on high-fat diets. Diabetes, obesity and metabolism. 1034-1049.
  • 2009. Dietary supplementation of tetradecylhioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed high fat diets. Diabetes, obesity and metabolism. 1034-1049.
  • 2009. Combination of fish oil and fish protein hydrolysate reduces the plasma cholesterol level with a concurrent increase in hepatic cholesterol level in high-fat-fed Wistar rats. Nutrition - The International Journal of Applied and Basic Nutritional Sciences. 98-104.
  • 2009. Cardiac peroxisome proliferator-activated receptor-alpha activation causes increased fatty acid oxidation, reducing efficiency and post-ischaemic functional loss. Cardiovascular Research (CVR). 519-526.
  • 2009. Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver. Psychopharmacology. 73-84.
  • 2009. A pan-PPAR ligand induces hepatic fatty acid oxidation in PPAR alpha-/- mice possibly through PGC-1 mediated PPAR delta coactivation. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1076-1083.
  • 2009. A complex role of activin A in non-alcoholic fatty liver disease. American Journal of Gastroenterology. 2196-2205.
  • 2009. A casein diet added isoflavone-enriched soy protein favorably affects biomarkers of steatohepatitis in obese Zucker rats. Nutrition - The International Journal of Applied and Basic Nutritional Sciences. 574-580.
  • 2008. Tetradecylthioacetic acid prevents the inflammatory response in two-kidney, one-clip hypertension. American Journal of Physiology. Regulatory Integrative and Comparative Physiology. R438-R447.
  • 2008. Tetradecylthioacetic acid downregulates cyclooxygenase 2 in the renal cortex of two-kidney, one-clip hypertensive rats. American Journal of Physiology. Regulatory Integrative and Comparative Physiology. R1866-R1873.
  • 2008. Pharmacology and safety of tetradecylthioacetic acid (TTA): phase-1 study. Journal of Cardiovascular Pharmacology. 410-417.
  • 2008. Long term treatment with tetradecylthioacetic acid improves the antioxidant status in obese Zucker (fa/fa) rats. Drug Metabolism Letters. 138-145.
  • 2008. Improved cognitive development among preterm infants attributable to early supplementation of human milk with docosahexaenoic acid and arachidonic acid. Pediatrics. 1137-1145.
  • 2008. Fenofibrate modulates cardiac and hepatic metabolism and increases ischemic tolerance in diet-induced obese mice. Journal of Molecular and Cellular Cardiology. 201-209.
  • 2008. Dietary single cell protein reduces fatty liver in obese Zucker rats. British Journal of Nutrition. 776-785.
  • 2007. Tetradecylselenoacetic acid, a PPAR ligand with antioxidant, antiinflammatory, and hypolipidemic properties. Arteriosclerosis, Thrombosis and Vascular Biology. 628-634.
  • 2007. Influence of dietary conjugated linoleic acid (CLA) and tetradecylthioacetic acid (TTA) on growth, lipid composition and key enzymes of fatty acid oxidation in liver and muscle of Atlantic cod (Gadus morhua L.). Aquaculture. 372-382.
  • 2007. Effects of dietary thia fatty acids on lipid composition, morphology and macrophage function of Atlantic salmon (Salmo salar L.) kidney. Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology. 103-111.
  • 2007. Effect of dietary tetradecylthioacetic acid on colon cancer growth studied by dynamic contrast enhanced MRI. Cancer Biology & Therapy. 1810-1816.
  • 2007. Dose-dependent coronary artery intimal thickening after local delivery of the anti-oxidant tetradecylthioacetic acid from stents. Atherosclerosis. e39-e47.
  • 2007. Does the capacity for energy utilization affect the survival of post-smolt Atlantic salmon, Salmo salar L., during natural outbreaks of infectious pancreatic necrosis? Journal of Fish Diseases. 399-409.
  • 2007. Differential effect of tetradecythioacetic acid on the renin-angiotensin system and blood pressure in SHR and 2-kidney, 1-clip hypertension. American Journal of Physiology - Renal, fluid and electrolyte physiology. F839-845.
  • 2006. Thia fatty acids with the sulfur atom in even or odd positions have opposite effects on fatty acid catabolism. Lipids. 169-177.
  • 2006. Prevention of Hypertension and Organ Damage in 2-Kidney, 1-Clip Rats by Tetradecylthioacetic Acid. Hypertension. 460-466.
  • 2006. Dietary soya protein concentrate enriched with isoflavones reduced fatty liver, increased hepatic fatty acid oxidation and decreased the hepatic mRNA level of VLDL receptor in obese Zucker rats. British Journal of Nutrition. 249-257.
  • 2006. Causes and prevention of tamoxifen-induced accumulation of triacylglycerol in rat liver. Journal of Lipid Research. 2223-2232.
  • 2006. A bioactively modified fatty acid improves survival and impairs metastasis in preclinical models of acute leukemia. Clinical Cancer Research. 3525-3531.
  • 2005. The metabolic syndrome and the hepatic fatty acid drainage hypothesis. Biochimie. 15-20.
  • 2005. The metabolic effects of thia fatty acids in rat liver depend on the position of the sulfur atom. Chemico-Biological Interactions. 71-81.
  • 2005. Oral ferrous fumarate or intravenous iron sucrose for patients with inflammatory bowel disease. Scandinavian Journal of Gastroenterology. 1058-1065.
  • 2005. Low-dose oral ferrous fumarate aggravated intestinal inflammation in rats with DSS-induced colitis. Inflammatory Bowel Diseases. 744-748.
  • 2005. In vitro culture of human osteosarcoma cell lines: a comparison of functional characteristics for cell lines cultured in medium without and with fetal calf serum. Journal of Cancer Research and Clinical Oncology. 377-384.
  • 2005. Glucose-induced lipogenesis in pancreatic beta-cells is dependent on SREBP-1. Molecular and Cellular Endocrinology. 94-106.
  • 2005. Effects of ferrous sulphate and non-ionic iron-polymaltose complex on markers of oxidative tissue damage in patients with inflammatory bowel disease. Alimentary Pharmacology and Therapeutics. 831-838.
  • 2005. Effect of 18 : 1n-9, 20 : 5n-3, and 22 : 6n-3 on lipid accumulation and secretion by Atlantic salmon hepatocytes. Lipids. 477-486.
  • 2005. Down-regulated expression of PPAR alpha target genes, reduced fatty acid oxidation and altered fatty acid composition in the liver of mice transgenic for hTNF alpha. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 235-246.
  • 2005. Dietary proteins with high isoflavone content or low methionine-glycine and lysine-arginine ratios are hypocholesterolaemic and lower the plasma homocysteine level in male Zucker fa/fa rats. British Journal of Nutrition. 321-330.
  • 2005. Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action? The Pharmacogenomics Journal. 298-304.
  • 2003. Modified fatty acids and their possible therapeutic targets in malingnant diseases. Expert Opin. Ther. Targets. 663-677.
  • 2003. Impact of mitochondrial beta-oxidation in fatty acid-mediated inhibition of glioma cell proliferation. Journal of Lipid Research. 118-127.
  • 2003. Immunomodulating effects of 3-thia fatty acids in activated peripheral blood mononuclear cells. European Journal of Clinical Investigation. 426-433.
  • 2003. Ferrous fumarate deteriorated plasma antioxidant status in patients with Crohn disease. Scandinavian Journal of Gastroenterology. 543-548.
  • 2003. Disturbed glutathione metabolism and decreased antioxidant levels in human immunodeficiency virus-infected patients during highly active antiretroviral therapy - potential immunomodulatory effects of antioxidants. Journal of Infectious Diseases. 232-238.
  • 2003. Circulating antioxidants and lipid peroxidation products in untreated tuberculosis patients in Ethiopia. American Journal of Clinical Nutrition. 117-122.
  • 2003. Changed energy state and increased mitochondrial beta-oxidation rate in liver of rats associated with lowered proton electrochemical potential and stimulated uncoupling protein 2 (UCP-2) expression. Journal of Biological Chemistry. 30525-30533.
  • 2003. Changed Energy State and Increased Mitochondrial B-Oxidation Rate in Liver of Rats Associated with Lowered Proton Electrochemical Potential and Stimulated Uncoupling Protein 2 (UCP-2) Expression. Journal of Biological Chemistry. 30525-30533.
  • 2003. Cataract formation in Atlantic salmon, Salmo salar L., smolt relative to dietary pro- and antioxidants and lipid levels. Journal of Fish Diseases. 213-229.
  • 2002. Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance. Journal of Lipid Research. 742-750.
  • 2002. Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance. Journal of Lipid Research. 742-750.
  • 2002. Nuclear import of factors involved in signaling is inhibited in C3H/10T1/2 cells treated with tetradecylthioacetic acid. Journal of Lipid Research. 1630-1640.
  • 2002. Metabolic effects of thia fatty acids. Current Opinion in Lipidology. 295-304.
  • 2002. Inhibition of rat lipoprotein oxidation after tetradecylthioacetic acid feeding. Biochemical Pharmacology. 1127-1135.
  • 2002. Human TNFa in transgenic mice induces differential changes in redox status and glutathione-regulating enzymes. The FASEB Journal.
  • 2002. Human TNF- alfa in transgenic mice induces differential changes in redox status and glutathione-regulating enzymes. The FASEB Journal. 1450-1452.
  • 2002. Evidence for selective induction of phosphoenolpyruvate carboxykinase gene expression by unsaturated and nonmetabolized fatty acids in adipocytes. Journal of Cellular Biochemistry. 651-661.
  • 2002. Antiproliferative effects of a non-beta-oxidizable fatty acid, tetradecylthioacetic acid, in native human acute myelogenous leukemia blast cultures. Leukemia. 2292-2301.
  • 2001. Transient up-regulation of liver mitochondrial thymidine kinase activity in proliferating mitochondria. IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology. 99-104.
  • 2001. Tetradecylthioacetic acid reduces stenosis development after balloon angioplasty injury of rabbit iliac arteries. Atherosclerosis. 269-275.
  • 2001. Tetradecylthioacetic acid inhibits growth of rat glioma cells ex vivo and in vivo via PPAR-dependent and PPAR-independent pathways. Carcinogenesis. 1747-1755.
  • 2001. Optimization of methods and treatment conditions for studying effects of fatty acids on cell growth. Lipids. 305-313.
  • 2001. Omega-3 fatty acids enhance tumor necrosis factor-alpha levels in heart transplant recipients. Transplantation. 706-711.
  • 2001. Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid. Journal of Investigative Dermatology. 702-712.
  • 2001. Long-term retention of a novel antioxidant sulphur-substituted fatty acid analogue after local delivery in porcine coronary arteries. Scandinavian Cardiovascular Journal. 101-106.
  • 2001. Interaction between chemokines and oxidative stress: possible pathogenic role in acute coronary syndromes. Journal of the American College of Cardiology. 485-491.
  • 2001. Interaction between chemokines and oxidative stress: possible pathogenic role in acute coronary syndromes. Journal of the American College of Cardiology. 485-491.
  • 2001. Growth reduction in glioma cells after treatment with tetradecylthioacetic acid: changes in fatty acid metabolism and oxidative status. Biochemical Pharmacology. 639-649.
  • 2001. Growth reduction in glioma cells after treatment with tetradecylthioacetic acid: changes in fatty acid metabolism and oxidative status. Biochemical Pharmacology. 639-649.
  • 2001. Effects of long-chain monounsaturated and n-3 fatty acids on fatty acid oxidation and lipid composition in rats. Annals of Nutrition and Metabolism. 30-37.
  • 2001. Effect of long-chain n-3 and mono-unsaturated fatty acids on fatty acid oxidation and lipid composition in rats. Annals of Nutrition and Metabolism. 30-37.
  • 2001. Acyl-CoA esters antagonize the effects of ligands on peroxisome proliferator-activated receptor alpha conformation, DNA binding, and interaction with Co-factors. Journal of Biological Chemistry. 21410-21416.
  • 2000. Virological and immunological effects of antioxidant treatment in patients with HIV infection. European Journal of Clinical Investigation. 905-914.
  • 2000. Virological and immunological effects of antioxidant treatment in patients with HIV infection. European Journal of Clinical Investigation. 905-14.
  • 2000. Virological and immunological effects of antioxidant treatment in patients with HIV infection. European Journal of Clinical Investigation. 905-914.
  • 2000. Tetradecylthioacetic acid and tetradecylselenoacetic acid inhibit lipid peroxidation and interact with superoxide radical. Free Radical Biology & Medicine. 1068-1078.
  • 2000. Tetradecylthioacetic acid and tetradecylselenoacetic acid inhibit lipid eroxidation and interact with superoxide radical. Free Radical Biology & Medicine. 1068-1078.
  • 2000. Proliferation of mitochondria and gene expression of carnitine palmitoyltransferase and fatty acyl-CoA oxidase in rat skeletal muscle, heart and liver by hypolipidemic fatty acids. Biology of the Cell. 317-329.
  • 2000. Proliferation of mitochondria and gene expression of carnitine palmitoyltransferase and fatty acyl-CoA oxidase in rat skeletal muscle, heart and liver by hypolipidemic fatty acids. Biology of the Cell. 317-329.
  • 2000. Preparation and NMR studies of 3-selenaheptadecanoic and 4-selenaoctadecanoic acid, RSe(CH2)nC(O)OH (R = -C14H29, n = 1 and 2), and their methyl esters. Journal of the Chemical Society. Perkin Transactions 2 (2001). 723-729.
  • 2000. Preparation and NMR studies of 3-selenaheptadecanoic and 4-selenaoctadecanoic acid, RSe(CH2)nC(O)OH (R = -C14H29, n = 1 and 2), and their methyl esters. Journal of the Chemical Society. Perkin Transactions 2 (2001). 723-729.
  • 2000. Peroxisome Proliferator-activated Receptor a Activators Improve Insulin Sensitivity and Reduce Adiposity. Journal of Biological Chemistry. 16638-16642.
  • 2000. Peroxisome Proliferator-activated Receptor a Activators Improve Insulin Sensitivity and Reduce Adipoisty. Journal of Biological Chemistry. 16638-16642.
  • 2000. Long-chain acyl-CoA esters and acyl-CoA binding protein are present in the nucleus of rat liver cells. Journal of Lipid Research. 538-545.
  • 2000. Long-chain acyl-CoA esters and acyl-CoA binding protein are present in the nucleus of rat liv er cells. Journal of Lipid Research. 538-545.
  • 2000. Correlation between Plasma Total Homocysteine and Copper in Patients with Peripheral Vascular Disease. Clinical Chemistry. 385-391.
  • 1998. On the effect of 2-deuterium- and 2-methyl-eicosapentaenoic acid derivatives on triglycerides, peroxisomal beta-oxidation and platelet aggregation in rats. Biochimica et Biophysica Acta. 193-203.
  • 1998. Influence of treatment with aminoglutethimide on plasma and red-blood-cell gluthatione status in breast cancer patients. Cancer Chemotherapy and Pharmacology. 46-52.
  • 1998. Generalized peroxisomal disorder in male twins: Fatty acid composition of serum lipids and response to n-3 fatty acids. Journal of Inherited Metabolic Disease. 662-670.
  • 1998. Docosahexaenoic and eicosapentaenoic acids are differently metabolized in rat liver during mitochondria and peroxisome proliferation. Journal of Lipid Research. 583-593.
  • 1997. Vitamins C and E interact in juvenile Atlantic salmon (Salmo salar, L). Free Radical Biology & Medicine. 137-149.
  • 1997. Up-regulated _D(9)-desaturase gene expression by hypolipidemic peroxisome-proliferating fatty acids results in increased oleic acid content in liver and VLDL: Accumulation of a _D(9)-desaturated metabolite of tetradecylthioacetic acid. Journal of Lipid Research. 554-563.
  • 1997. Tetradecylthioacetic acid inhibits the oxidative modification of low density lipoprotein and 8-hydroxydeoxyguanosine formation in vitro. Arteriosclerosis, Thrombosis and Vascular Biology. 3255-3262.
  • 1997. Tetradecylthioacetic acid inhibits the oxidative modification of low density lipoprotein and 8-hydroxydeoxyguanosine formation in vitro. Arteriosclerosis, Thrombosis and Vascular Biology. 3255-3262.
  • 1997. Tetradecylthioacetic Acid Inibits the Oxidative Modification of Low Density Lipoprotein and 8-Hydroxydeoxyguanosine formation in Vitro. Arteriosclerosis, Thrombosis and Vascular Biology.
  • 1997. On the effects of thia fatty acid analogues on hydrolases involved in the degradation of metabolisable and non-metabolisable acyl-CoA esters. Xenobiotica. 197-202.
  • 1997. Mitochondrion is the principal target for nutritional and pharmacological control of triglyceride metabolism. Journal of Lipid Research. 183-190.
  • 1997. Hypotriacylglycerolemic component of fish oil. Prostaglandins, Leukotrienes and Essential Fatty Acids. 387-388.
  • 1997. Enhanced hepatic fatty acid oxidation and unpregulated carnitinu palmitoyl-transferase II gene expression by methyl 3-tharoctadeca6,9,12,15 - tetraenoate in rats. Journal of Lipid Mediators and Cell Signalling. 115-134.
  • 1997. Elevated plasma levels of reduced homocysteine in common variable immunodeficiency - a marker of enhanced oxidative stress. European Journal of Clinical Investigation. 730-790.
  • 1997. Elevated plasma levels of reduced homocysteine in common variable immunodeficiency - a marker of enhanced oxidative stress. European Journal of Clinical Investigation. 723-730.
  • 1997. Eikcosapentaenoic acid and sulphur substituted fatty acid analogues inhibit the proliferation of human breast cancer cells in culture. Breast Cancer Research and Treatment. 229-239.
  • 1997. Effect of 3-thia fatty acids on the lipid composition of rat liver, lipoproteins, and heart. Journal of Lipid Research. 1522-1534.
  • 1997. 1-@(Carboxymethylthio@)-tetradecane attenuates PDGF- and TPA-induced c-fos mRNA expression and increases the formation of phosphatidylethanolamine with a shift from less to more polar molecular species in C3H/10 1/2 mouse fibroblasts. Experimental Cell Research. 330-340.
  • 1996. Peroxisomal fatty acid oxidation capacity is more resistant to ischaemic and reperfusion injury than mitochondrial fatty acid oxidation capacity in feline hearts. Acta Physiologica Scandinavica. 133-145.
  • 1996. Long-term effect of tetradecylthioacetic acid: a study on lipid profile and fatty acid composition and oxidation in different rat organs. Biochimica et Biophysica Acta. 86-96.
  • 1996. Eicosapentaenoic acid, but not docosahexaenoic acid, increases mitochondrial fatty acid oxidation and upregulates 2,4-dienoyl-CoA reductase gene expression in rats. Lipids. 579-592.
  • 1996. Chronic administration of eicosapentaenoic acid and docosahexaenoic acid as ethyl esters reduced plasma cholesterol and changed fatty acid composition in rat blood and organs. Lipids. 169-178.
  • 1996. Carvedilol protects against lethal reperfusion injury through antiadrenergic mechanisms. Journal of Cardiovascular Pharmacology. 409-417.
  • 1996. Carvedilol improves function and reduces infarct size in the feline myocardium by protecting against lethal reperfusion injury. European Journal of Pharmacology. 99-107.
  • 1996. A hypolipidemic peroxisome proliferating fatty acid induces polydispersity of rat liver mitochondria. Biology of the Cell. 105-112.
  • 1996. 3-Thia fettsyrer - et nytt lipidsenkende legemiddel? NBS-nytt. 6-11.
  • 1995. Tetradecylthioacetic acid (a 3-thia fatty acid) decreases triacylglycerol secretion in CaCo-2 cells. Journal of Lipid Research. 535-543.
  • 1995. Fatty acid-CoA oxidase activity is induced before long-chain acyl-CoA hydrolase activity and acyl-CoA binding protein in liver of rats treated with peroxisome proliferating 3-thia fatty acids. Xenobiotica. 1181-1194.
  • 1994. On the mechanism of 3-thia fatty acids. Lipid-forum.
  • 1994. Modulation of plasma and hepatic oxidative status and changes in plasma lipid profile by n-3 (EPA and DHA), n-6 (corn-oil) and a 3-thia fatty acid in rats. Biochimica et biophysica acta. Specialized section on nucleic acids and related subjects. 238-244.
  • 1994. Gas chromatographic measurement of 3- and 4-thia fatty acids incorporated into various classes of rat liver lipids during feeding experiments. Journal of chromatography. B. 1-10.
  • 1994. Docosahexaenoic induced lipid accumulation in myocardial cells of rats. Scandinavian Journal of Clinical and Laboratory Investigation. 665-671.
  • 1994. A study on lipid metabolism in heart and liver of cholesterol- and pectin-fed rats. British Journal of Nutrition. 181-192.
  • 1993. The triglyceride-lowering effect on omega-3 fatty acids. Is it all in eicosapentaenoc acid. Omega-3 News. 5-8.
  • 1993. Structural and metaboli requirements for activators of the peroxisome proliferator activated receptor (PPAR). Biochemical Pharmacology. 36-43.
  • 1993. On the mechanism of the hypolipidemic effect on sulfur-substituted hexadecanediotic (3-thiadicarboxylic acid) in normolipidemic rats. Journal of Lipid Research. 1177-1185.
  • 1993. Modulation of phosphatidylcholine biosynthesis by peroxisomal proliferating fatty acid analogs. Lipids. 795-801.
  • 1993. Docosahexaenoic Acid Shows no Triglyceride-Lowering Effects, but increases the Peroxisomal Fatty Acid Oxidation in Liver of Rats. Journal of Lipid Research. 13-22.
  • 1993. Cholesterol induced lipid accumulation in myocardial cells of rats. Cardiovascular Research (CVR). 442-446.
  • 1993. Cholesterol induced lipid accumulation in myocardial cells of rats. Cardiovascular Research (CVR). 442-446.
  • 1993. Allupurinol does not affect the concentration of endogenous glutathione in liver cells in rats after 60 min of normothermic liver ischemia. European Journal of Surgery. 355-359.
  • 1992. The activity and subcellular distribution of the peroxisomal enzyme acyl-CoA oxidase in human bloodplatelets. Biochemical Journal. 829-831.
  • 1992. Relationship between translocation of long-chain acyl-CoA hydrolase, phosphatidate phosphohydrolase and CTP:Phosphocholine cytidylyltransferase and the synthesis of triglycerides and phosphatidylcholine in rat liver. Lipids. 241-147.
  • 1992. Eicosapentaenoic acid at hypotriglyceridemic dose enhances the hepatic antiocidant defense in mice. Lipids. 968-972.
  • 1992. Camparative effects of oxygen and sulfur-substituted fatty acids on serum lipids and mitochondrial and peroxisomal fatty acid oxidation in rat. Biochemical Pharmacology. 815-822.
  • 1990. Effect of 3- and 4-thia-substituted fatty acids on glycerolipid metabolism and mitochondrial beta-oxidation in rat liver. Biochemical Pharmacology. 2005-2012.
Academic lecture
  • 2020. Low 3-hydroxyisobutyrate (3-HIB) and high methylmalonic acid (MMA) levels in plasma reflect increased hepatic fatty acid oxidation.
  • 2018. Effect of tetradecylthioacetic acid (TTA) on energy intake and body fat deposition in silver foxes (Vulpes vulpes).
  • 2015. Plasma Interferon-inducible Protein 10 Levels, T-cell Activation and Regulation are Increased in HIV Immunological Non-Responders.
  • 2008. Administration of tetradecylthioacetic acid (TTA) in mice accelerates myocardial FA oxidation via increased expression of pparα target genes.
  • 2006. The Antioxidant,Anti-inflammatory and Hypolipidemic Properties of a Seleno-substituted Fatty Acid.
  • 2005. A pan-PPAR ligand induces differential coactivation of PPARs by SRCs and PGC-1.
  • 2004. Tetradecylthioacetic acid induces ligand dependent coactivation of PPARs by PGC-1 and SRC coactivators.
  • 2004. Different effects of PPAR ligands on cardiac metabolism in mice fed high fat diet.
  • 2004. Decreased TNFα induced endothelial activation in the presence of a new bioactive fatty acid.
  • 2003. Effects of Omega-3 Fatty Acids on DSS-induced Colitis in Rats.
  • 2003. Effect of Ferrous Fumarate Supplementation in Dextran Sulfate Sodium Colitis in Rats.
  • 2001. Tetradecylthioacetic acid inhibits growth of rat glioma cells ex vivo and in vivo via PPAR-dependent and PPAR-independent pathways.
  • 2001. PPAR-activating 3-thia fatty acid influences the growth potential and metabolism in glioma cells.
  • 2001. Expression of PPARa target genes improve insulin action and reduce adiposity.
  • 2001. Dietary treatment of highly concentrated omega-3 fatty acids increases tumor necrosis factor alpha and reduces antioxidant levels in stable heart transplant recipients.
  • 2001. 3-Thia fatty acid induces mitochondrial alterations and triggers apoptosis in cancer cells.
  • 2000. Expression of PPAR alpha target genes improve insulin action and reduce adiposity.
  • 1998. On the antioxidant effect of tetradecylthioacetic acid and tetradecylselenoacetic acid.
  • 1998. Metabolic effects of 3-thia fatty acid in cancer cells.
  • 1998. Antioxidant properties of 3-Thia fatty acids.
  • 1994. Zellweger-like syndrome: Prolonged survival in male twins during treatment with n-3 fatty acids.
Abstract
  • 2012. Combined thermal and electrical muscle stimulation reduce visceral fat and improve lipid profile during weight loss. Circulation. E679-E680.
  • 2010. Low circulating eicosatetraenoic acid and high vaccenic acid are associated with disease severity and predict mortality in heart failure. European Heart Journal. 570-570.
  • 2008. TTA is a pan PPAR ligand which markedly stimulates fatty acid oxidation following in vivo administration. Cardiovascular Drugs and Therapy. 142-143.
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Academic literature review
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  • 2010. The Role of PPAR alpha Activation in Liver and Muscle. 11 pages.

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