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Rolf Kristian Berge

Professor
  • E-mailRolf.Berge@uib.no
  • Phone+47 55 97 30 98
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • Arge, Regin; Thomassen, Magny S.; Berge, Rolf Kristian; Zambonino-Infante, Jose L; Terjesen, Bendik Fyhn; Oehme, Maike Marlene; Rørvik, Kjell-Arne. 2014. Reduction of early sexual maturation in male SO Atlantic salmon (Salmo salar L.) by dietary supplementation of tetradecylthioacetic acid (TTA). Aquaculture Research. 922-933.
  • Bjørndal, Bodil; Grimstad, Tore; Cacabelos, Daniel; Nylund, Kim; Aasprong, Ole Gunnar; Omdal, Roald; Portero-Otin, Manuel; Pamplona, Reinald; Hausken, Trygve; Lied, Gülen Arslan; Berge, Rolf Kristian. 2013. Tetradecylthioacetic acid attenuates inflammation and has antioxidative potential during experimental colitis in rats. Digestive Diseases and Sciences. 97-106.
  • Øie, Erik; Berge, Rolf Kristian; Ueland, Thor; Dahl, Christen Peder; Edvardsen, Thor; Beitnes, Jan Otto; Bohov, Pavol; Aukrust, Pål; Yndestad, Arne. 2013. Tetradecylthioacetic Acid Increases Fat Metabolism and Improves Cardiac Function in Experimental Heart Failure. Lipids. 139-154.
  • Viiri, Leena E.; Full, Louise E.; Navin, Tina J.; Begum, Shajna; Didangelos, Athanasios; Astola, Nagore; Berge, Rolf Kristian; Seppäla, Ilkka; Shalhoub, Joseph; Franklin, Ian J.; Perretti, Mauro; Lehtimaki, Terho; Davies, Alun H.; Wait, Robin; Monaco, Claudia. 2013. Smooth muscle cells in human atherosclerosis: Proteomic profiling reveals differences in expression of Annexin A1 and mitochondrial proteins in carotid disease. Journal of Molecular and Cellular Cardiology. 65-72.
  • Vigerust, Natalya Filipchuk; Bjørndal, Bodil; Bohov, Pavol; Brattelid, Trond; Svardal, Asbjørn M.; Berge, Rolf Kristian. 2013. Krill oil versus fish oil in modulation of inflammation and lipid metabolism in mice transgenic for TNF-α. European Journal of Nutrition. 1315-1325.
  • Kousoulaki, Katerina; Rønnestad, Ivar; Olsen, Hanne Jorun; Rathore, Raja Mansingh; Campbell, Paddy; Nordrum, Sigve; Berge, Rolf Kristian; Mjøs, Svein Are; Kalananthan, Tharmini; Albrektsen, Sissel. 2013. Krill hydrolysate free amino acids responsible for feed intake stimulation in Atlantic salmon (Salmo salar). Aquaculture Nutrition. 47-61.
  • Hagland, Hanne; Hodneland, Linn I.; Burri, Lena; Nikolaisen, Julie; Berge, Rolf Kristian; Tronstad, Karl Johan. 2013. Induction of mitochondrial biogenesis and respiration is associated with mTOR regulation in hepatocytes of rats treated with the pan-PPAR activator tetradecylthioacetic acid (TTA). Biochemical and Biophysical Research Communications - BBRC. 573-578.
  • Bjørndal, Bodil; Brattelid, Trond; Strand, Elin; Vigerust, Natalya Filipchuk; Svingen, Gard Frodahl Tveitevåg; Svardal, Asbjørn M.; Nygård, Ottar; Berge, Rolf Kristian. 2013. Fish Oil and the Pan-PPAR Agonist Tetradecylthioacetic Acid Affect the Amino Acid and Carnitine Metabolism in Rats. PLOS ONE. 9 pages.
  • Ueland, Thor; Svardal, Asbjørn M.; Øie, Erik; Askevold, Erik Tandberg; Nymoen, Ståle H.; Bjørndal, Bodil; Dahl, Christen Peder; Gullestad, Lars; Berge, Rolf Kristian; Aukrust, Pål. 2013. Disturbed carnitine regulation in chronic heart failure - Increased plasma levels of palmitoyl-carnitine are associated with poor prognosis. International Journal of Cardiology. 1892-1899.
  • Strand, Elin; Pedersen, Eva Kristine Ringdal; Svingen, Gard Frodahl Tveitevåg; Schartum-Hansen, Hall; Rebnord, Eirik Wilberg; Bjørndal, Bodil; Seifert, Reinhard; Bohov, Pavol; Meyer, Klaus; Hiltunen, J Kalervo; Nordrehaug, Jan Erik; Nilsen, Dennis W.T.; Berge, Rolf Kristian; Nygård, Ottar. 2013. Dietary intake of n-3 long-chain polyunsaturated fatty acids and risk of myocardial infarction in coronary artery disease patients with or without diabetes mellitus: a prospective cohort study. BMC Medicine.
  • Bjørndal, Bodil; Berge, Christ; Ramsvik, Marie Sannes; Svardal, Asbjørn M.; Bohov, Pavol; Skorve, Jon; Berge, Rolf Kristian. 2013. A fish protein hydrolysate alters fatty acid composition in liver and adipose tissue and increases plasma carnitine levels in a mouse model of chronic inflammation. Lipids in Health and Disease. 11 pages.
  • Borgeraas, Heidi; Strand, Elin; Pedersen, Eva Kristine Ringdal; Dierkes, Jutta; Ueland, Per Magne; Seifert, Reinhard; Rebnord, Eirik Wilberg; Bohov, Pavol; Berge, Rolf Kristian; Nilsen, Dennis W.T.; Nygård, Ottar. 2012. Omega-3 status and the relationship between plasma asymmetric dimethylarginine and risk of myocardial infarction in patients with suspected coronary artery disease. Cardiology Research and Practice. 11 pages.
  • Skrede, Silje; Fernø, Johan; Vázquez, Maria Jesús; Fjær, Sveinung; Pavlin, Tina; Lunder, Niclas; Vidal-Puig, Antonio; Diéguez, Carlos; Berge, Rolf Kristian; López, Miguel; Steen, Vidar Martin. 2012. Olanzapine, but not aripiprazole, weight-independently elevates serum triglycerides and activates lipogenic gene expression in female rats. International Journal of Neuropsychopharmacology. 163-179.
  • Strand, Elin; Bjørndal, Bodil; Nygård, Ottar; Burri, Lena; Berge, Christ; Bohov, Pavol; Christensen, Bjørn Jostein; Berge, Kjetil; Wergedahl, Hege; Viste, Asgaut; Berge, Rolf Kristian. 2012. Long-term treatment with the pan-PPAR agonist tetradecylthioacetic acid or fish oil is associated with increased cardiac content of n-3 fatty acids in rat. Lipids in Health and Disease. 11 pages.
  • Skrede, Silje; Fernø, Johan; Bjørndal, Bodil; Brede, Wenche Rødseth; Bohov, Pavol; Berge, Rolf Kristian; Steen, Vidar Martin. 2012. Lipid-lowering effects of tetradecylthioacetic acid in antipsychotic-exposed, female rats: challenges with long-term treatment. PLOS ONE. 11 pages.
  • Bjørndal, Bodil; Vik, Rita; Brattelid, Trond; Vigerust, Natalya Filipchu; Burri, Lena; Bohov, Pavol; Nygård, Ottar; Skorve, Jon; Berge, Rolf Kristian. 2012. Krill powder increases liver lipid catabolism and reduces glucose mobilization in tumor necrosis factor-alpha transgenic mice fed a high-fat diet. Metabolism: Clinical and Experimental. 1461-1472.
  • Grammes, Fabian; Rørvik, Kjell-Arne; Thomassen, Magny S.; Berge, Rolf Kristian; Takle, Harald Rune. 2012. Genome wide response to dietary tetradecylthioacetic acid supplementation in the heart of Atlantic Salmon (Salmo salar L). BMC Genomics. 13 pages.
  • Vigerust, Natalya Filipchu; Bohov, Pavol; Bjørndal, Bodil; Seifert, Reinhard; Nygård, Ottar; Svardal, Asbjørn M.; Glintborg, Dorte; Berge, Rolf Kristian; Gaster, Michael. 2012. Free carnitine and acylcarnitines in obese patients with polycystic ovary syndrome and effects of pioglitazone treatment. Fertility and Sterility. 1620-1626,e1.
  • Vigerust, Natalya Filipchu; Cacabelos, Daniel; Burri, Lena; Berge, Kjetil; Wergedahl, Hege; Christensen, Bjørn Jostein; Portero-Otin, Manuel; Viste, Asgaut; Pamplona, Reinald; Berge, Rolf Kristian; Bjørndal, Bodil. 2012. Fish oil and 3-thia fatty acid have additive effects on lipid metabolism but antagonistic effects on oxidative damage when fed to rats for 50 weeks. Journal of Nutritional Biochemistry. 1384-1393.
  • Pettersen, Reidar J; Salem, Mohamed Abdou Mohamed; Rotevatn, Svein; Kuiper, Karel Kier-Jan; Larsen, Terje H; Bohov, Pavol; Berge, Rolf Kristian; Nordrehaug, Jan Erik. 2012. Effects of local delivery of Tetradecylthioacetic acid within the injured coronary vessel wall. Scandinavian Cardiovascular Journal. 366-373.
  • Grimstad, Tore; Bjørndal, Bodil; Cacabelos, Daniel; Aasprong, Ole Gunnar; Janssen, Emilius Adrianus Maria; Omdal, Roald; Svardal, Asbjørn M.; Hausken, Trygve; Bohov, Pavol; Portero-Otin, Manuel; Pamplona, Reinald; Berge, Rolf Kristian. 2012. Dietary supplementation of krill oil attenuates inflammation and oxidative stress in experimental ulcerative colitis in rats. Scandinavian Journal of Gastroenterology. 49-58.
  • Bjørndal, Bodil; Burri, Lena; Wergedahl, Hege; Svardal, Asbjørn M.; Bohov, Pavol; Berge, Rolf Kristian. 2012. Dietary supplementation of herring roe and milt enhances fatty acid catabolism in female mice transgenic for hTNFa. European Journal of Nutrition. 741-753.
  • Christensen, Bjørn Jostein; Berge, Kjetil; Wergedahl, Hege; Bohov, Pavol; Pettersen, Caroline Hild; Schønberg, Svanhild Margrethe Arentz; Berge, Rolf Kristian; Svendsen, Einar; Viste, Asgaut. 2012. Bioactive fatty acids reduce development of gastric cancer following duodenogastric reflux in rats. Surgical Science. 34-42.
  • Jassim, Goran; Skrede, Silje; Vázquez, Maria Jesús; Vik-Mo, Audun Osland; Lunder, Niclas; Diéguez, Carlos; Vidal-Puig, Antonio; Berge, Rolf Kristian; López, Miguel; Steen, Vidar Martin; Fernø, Johan; Wergedahl, Hege. 2012. Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat. Psychopharmacology. 783-794.
  • Lundemo, Anne Gøril; Pettersen, Caroline Hild; Berge, Kjetil; Berge, Rolf Kristian; Schønberg, Svanhild Margrethe Arentz. 2011. Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells - gene expression profiling implies endoplasmic reticulum stress. Lipids in Health and Disease. 11 pages.
  • Burri, Lena; Bjørndal, Bodil; Wergedahl, Hege; Berge, Kjetil; Bohov, Pavol; Svardal, Asbjørn M.; Berge, Rolf Kristian. 2011. Tetradecylthioacetic acid increases hepatic mitochondrial beta-oxidation and alters fatty acid composition in a mouse model of chronic inflammation. Lipids. 679-689.
  • Bhurruth-Alcor, Yushma; Røst, Therese Halvorsen; Jorgensen, Michael R.; Kontogiorgis, Christos; Skorve, Jon; Cooper, Robert G.; Sheridan, Joseph M.; Hamilton, William D.O.; Heal, Jonathan R.; Berge, Rolf Kristian; Miller, Andrew D. 2011. Synthesis of novel PPARα/γ dual agonists as potential drugs for the treatment of the metabolic syndrome and diabetes type II designed using a new de novo design program protobuild. Organic and biomolecular chemistry. 1169-1188.
  • Stunes, Astrid Kamilla; Westbroek, Irene; Fossmark, Reidar; Berge, Rolf Kristian; Reseland, Janne Elin; Syversen, Unni. 2011. Skeletal effects of the saturated 3-thia fatty acid tetradecylthioacetic acid in rats. PPAR Research. 10 pages.
  • Grimstad, Tore; Berge, Rolf Kristian; Bohov, Pavol; Skorve, Jon; Gøransson, Lasse; Omdal, Roald; Aasprong, Ole Gunnar; Haugen, Margaretha; Meltzer, Helle Margrete; Hausken, Trygve. 2011. Salmon diet in patients with active ulcerative colitis reduced the simple clinical colitis activity index and increased the anti-infl ammatory fatty acid index – a pilot study. Scandinavian Journal of Clinical and Laboratory Investigation. 68-73.
  • Dahl, Tuva Børresdatter; Ranheim, Trine; Holm, Sverre; Berge, Rolf Kristian; Aukrust, Pål; Halvorsen, Bente. 2011. Nicotinamide phosphoribosyltransferase and lipid accumulation in macrophages. European Journal of Clinical Investigation. 1098-1104.
  • Lillerud, Linn Elisabeth; Berge, Rolf Kristian; Beitnes, Jan Otto; Berge, Kjetil; Vik, Hogne; Aukrust, Pål; Gullestad, Lars; Vinge, Leif Erik; Øie, Erik. 2011. Krill oil attenuates left ventricular dilatation after myocardial infarction in rats. Lipids in Health and Disease. 9 pages.
  • Øie, Erik; Ueland, Thor; Dahl, Christen Peder; Bohov, Pavol; Berge, Christ; Yndestad, Arne; Gullestad, Lars; Aukrust, Pål; Berge, Rolf Kristian. 2011. Fatty acid composition in chronic heart failure: low circulating levels of eicosatetraenoic acid and high levels of vaccenic acid are associated with disease severity and mortality. Journal of Internal Medicine. 263-272.
  • Khalid, Ahmed Murtaz; Hafstad, Anne Dragøy; Larsen, Terje; Severson, david lester; Boardman, Neoma Tove; Hagve, Martin; Berge, Rolf Kristian; Aasum, Ellen. 2011. Cardioprotective effect of the PPAR ligand tetradecylthioacetic acid in type 2 diabetic mice. American Journal of Physiology. Heart and Circulatory Physiology. H2116-H2122.
  • Morken, Tore; Bohov, Pavol; Skorve, Jon; Ulvik, Rune Johan; Aukrust, Pål; Berge, Rolf Kristian; Livden, John Karsten. 2011. Anti-inflammatory and hypolipidemic effects of the modified fatty acid tetradecylthioacetic acid in psoriasis -- a pilot study. Scandinavian Journal of Clinical and Laboratory Investigation. 269-273.
  • Pedersen, Eva Kristine Ringdal; Midttun, Øivind; Ueland, Per Magne; Schartum-Hansen, Hall; Seifert, Reinhard; Igland, Jannicke; Nordrehaug, Jan Erik; Ebbing, Marta; Svingen, Gard Frodahl; Bleie, Øyvind; Berge, Rolf Kristian; Nygård, Ottar. 2010. Systemic Markers of Interferon-–Mediated Immune Activation and Long-Term Prognosis in Patients With Stable Coronary Artery Disease. Arteriosclerosis, Thrombosis and Vascular Biology.
  • Gudbrandsen, Oddrun Anita; Rodriguez, Enrique; Wergedahl, Hege; Mørk, Sverre; Reseland, Janne E.; Skorve, Jon; Palou, Andreu; Berge, Rolf Kristian. 2009. Trans-10, cis-12-conjugated linoleic acid reduces the hepatic triacylglycerol content and the leptin mRNA level in adipose tissue in obese Zucker fa/fa rats. British Journal of Nutrition. 803-815.
  • Lovas, K; Rost, TH; Skorve, Jon; Ulvik, Rune Johan; Gudbrandsen, Oddrun Anita; Bohov, Pavol; Wensaas, Andreas J.; Rustan, Arild C.; Berge, Rolf Kristian; Husebye, Eystein Sverre. 2009. Tetradecylthioacetic acid attenuates dyslipidaemia in male patients with type 2 diabetes mellitus, possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidation. Diabetes, obesity and metabolism. 304-314.
  • Alne, Henriette; Thomassen, Magny Skinlo; Takle, Harald Rune; Terjesen, Bendik Fyhn; Grammes, Fabian; Oehme, Maike Marlene; Refstie, Ståle; Sigholt, Trygve; Berge, Rolf Kristian; Rørvik, Kjell-Arne. 2009. Increased survival by feeding tetradecylthioacetic acid during a natural outbreak of heart and skeletal muscle inflammation in S0 Atlantic salmon, Salmo salar L. Journal of Fish Diseases. 953-961.
  • Løvås, K; Wensaas, AJ; Røst, TH; Rustan, AC; Rokling-Andersen, MH; Skorve, Jon; Caesar, R; Ulvik, RJ; Jensen, J; Kaalhus, O; Bohov, P; Graff, Bjørn Anton; Gudbrandsen, OA; Berge, RK; Husebye, ES; Drevon, CA. 2009. Dietary supplementation of tetradecylthioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed on high-fat diets. Diabetes, obesity and metabolism. 1034-1049.
  • Wensaas, Andreas Johansen; Rustan, Arild; Rokling-Andersen, Merethe; Caesar, Robert; Jensen, Jørgen; Kaalhus, O; Graff, BA; Gulbrandsen, OA; Berge, RK; Drevon, Christian A. 2009. Dietary supplementation of tetradecylhioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed high fat diets. Diabetes, obesity and metabolism. 1034-1049.
  • Røst, Therese Halvorsen; Moi, Line Leonore Haugan; Berge, Kjetil; Staels, Bart; Mellgren, Gunnar; Berge, Rolf Kristian. 2009. A pan-PPAR ligand induces hepatic fatty acid oxidation in PPAR alpha-/- mice possibly through PGC-1 mediated PPAR delta coactivation. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1076-1083.
  • Yndestad, A; Haukeland, John Willy; Dahl, Tuva Børresdatter ; Bjoro, K; Gladhaug, Ivar Prydz; Berge, Christ; Damas, Jan Kristian; Haaland, Terese; Loberg, EM; Linnestad, Paul; Birkeland, Kåre; Konopski, Zbigniew; Halvorsen, B; Berge, Rolf Kristian; Aukrust, P. 2009. A complex role of activin A in non-alcoholic fatty liver disease. American Journal of Gastroenterology. 2196-2205.
  • Pettersen, Reidar J.; Salem, Mohamed; Skorve, Jon; Ulvik, Rune Johan; Berge, Rolf Kristian; Nordrehaug, Jan Erik. 2008. Pharmacology and safety of tetradecylthioacetic acid (TTA): phase-1 study. Journal of Cardiovascular Pharmacology. 410-417.
  • Aasum, Ellen; Khalid, Ahmed Murtaz; Gudbrandsen, Oddrun Anita; How, Ole-Jakob; Berge, Rolf; Larsen, Terje. 2008. Fenofibrate modulates cardiac and hepatic metabolism and increases ischemic tolerance in diet-induced obese mice. Journal of Molecular and Cellular Cardiology. 201-209.
  • Gudbrandsen, Oddrun Anita; Wergedahl, Hege; Liaset, Bjørn; Espe, Marit; Mørk, Sverre; Berge, Rolf Kristian. 2008. Dietary single cell protein reduces fatty liver in obese Zucker rats. British Journal of Nutrition. 776-785.
  • Dyrøy, Endre; Røst, Therese Halvorsen ; Pettersen, Reidar J.; Halvorsen, Bente; Gudbrandsen, Oddrun Anita; Ueland, Thor; Muna, Ziad Ahmed; Muller, Fredrik; Nordrehaug, Jan Erik; Aukrust, Pål; Berge, Rolf Kristian. 2007. Tetradecylselenoacetic acid, a PPAR ligand with antioxidant, antiinflammatory, and hypolipidemic properties. Arteriosclerosis, Thrombosis and Vascular Biology. 628-634.
  • Kennedy, Sean R.; Bickerdike, Ralph; Berge, Rolf Kristian; Porter, Allen R.; Tocher, Douglas R. 2007. Influence of dietary conjugated linoleic acid (CLA) and tetradecylthioacetic acid (TTA) on growth, lipid composition and key enzymes of fatty acid oxidation in liver and muscle of Atlantic cod (Gadus morhua L.). Aquaculture. 372-382.
  • Gjøen, Tor; Kleveland, Ellen Johanne; Moya-Falcón, Corina; Frøystad, Marianne K.; Vegusdal, Anne; Hvatturn, Erlend; Berge, Rolf Kristian; Ruyter, Bente. 2007. Effects of dietary thia fatty acids on lipid composition, morphology and macrophage function of Atlantic salmon (Salmo salar L.) kidney. Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology. 103-111.
  • Jensen, Line Rørstad; Berge, Kjetil; Bathen, Tone Frost; Wergedahl, Hege; Schønberg, Svanhild A.; Bofin, Anna; Berge, Rolf Kristian; Gribbestad, Ingrid S. 2007. Effect of dietary tetradecylthioacetic acid on colon cancer growth studied by dynamic contrast enhanced MRI. Cancer Biology & Therapy. 1810-1816.
  • Kuiper, Karel Kier-Jan; Salem, M.; Gudbrandsen, Oddrun Anita; Muna, Ziad Ahmed; Berge, Rolf Kristian; Nordrehaug, Jan Erik. 2007. Dose-dependent coronary artery intimal thickening after local delivery of the anti-oxidant tetradecylthioacetic acid from stents. Atherosclerosis. e39-e47.
  • Rørvik, Kjell-Arne; Alne, Henriette; Gaarder, Mari; Ruyter, Bente; Måseide, Niels Petter; Jakobsen, Jan Vidar; Berge, Rolf Kristian; Sigholt, Trygve; Thomassen, Magny Skinlo. 2007. Does the capacity for energy utilization affect the survival of post-smolt Atlantic salmon, Salmo salar L., during natural outbreaks of infectious pancreatic necrosis? Journal of Fish Diseases. 399-409.
  • Bivol, Liliana-Monica; Berge, Rolf Kristian; Iversen, Bjarne Magnus. 2007. Differential effect of tetradecythioacetic acid on the renin-angiotensin system and blood pressure in SHR and 2-kidney, 1-clip hypertension. American Journal of Physiology - Renal, fluid and electrolyte physiology. F839-845.
  • Dyrøy, Endre; Wergedahl, Hege; Skorve, Jon Andreas; Gudbrandsen, Oddrun Anita; Songstad, Jon; Berge, Rolf Kristian. 2006. Thia fatty acids with the sulfur atom in even or odd positions have opposite effects on fatty acid catabolism. Lipids. 169-177.
  • Gudbrandsen, Oddrun Anita; Hultström, Michael; Leh, Sabine; Bivol, Liliana-Monica; Vågnes, Øyvind Brune; Berge, Rolf Kristian; Iversen, Bjarne Magnus. 2006. Prevention of Hypertension and Organ Damage in 2-Kidney, 1-Clip Rats by Tetradecylthioacetic Acid. Hypertension. 460-466.
  • Gudbrandsen, Oddrun Anita; Wergedahl, Hege; Mørk, Sverre; Liaset, Bjørn; Espe, Marit; Berge, Rolf Kristian. 2006. Dietary soya protein concentrate enriched with isoflavones reduced fatty liver, increased hepatic fatty acid oxidation and decreased the hepatic mRNA level of VLDL receptor in obese Zucker rats. British Journal of Nutrition. 249-257.
  • Gudbrandsen, Oddrun Anita; Røst, Therese Halvorsen ; Berge, Rolf Kristian. 2006. Causes and prevention of tamoxifen-induced accumulation of triacylglycerol in rat liver. Journal of Lipid Research. 2223-2232.
  • Iversen, Per O.; Sørensen, Dag R.; Tronstad, Karl Johan; Gudbrandsen, Oddrun; Rustan, Arild C.; Berge, Rolf Kristian; Drevon, Christian A. 2006. A bioactively modified fatty acid improves survival and impairs metastasis in preclinical models of acute leukemia. Clinical Cancer Research. 3525-3531.
  • Erichsen, Kari; Ulvik, Rune Johan; Nysæter, Gunnar; Johansen, Jack; Ostborg, Jens; Berstad, Arnold; Berge, Rolf Kristian; Hausken, Trygve. 2005. Oral ferrous fumarate or intravenous iron sucrose for patients with inflammatory bowel disease. Scandinavian Journal of Gastroenterology. 1058-1065.
  • Bruserud, Øystein; Tronstad, Karl Johan; Berge, Rolf Kristian. 2005. In vitro culture of human osteosarcoma cell lines: a comparison of functional characteristics for cell lines cultured in medium without and with fetal calf serum. Journal of Cancer Research and Clinical Oncology. 377-384.
  • Sandberg, Maria B; Fridriksson, Jakob; Madsen, Lise; Rishi, Vika; Vinson, Charles; Holmsen, Holm A; Berge, Rolf Kristian; Mandrup, Susanne. 2005. Glucose-induced lipogenesis in pancreatic beta-cells is dependent on SREBP-1. Molecular and Cellular Endocrinology. 94-106.
  • Erichsen, Kari; Ulvik, Rune Johan; Grimstad, Tore; Berstad, Arnold; Berge, Rolf Kristian; Hausken, Trygve. 2005. Effects of ferrous sulphate and non-ionic iron-polymaltose complex on markers of oxidative tissue damage in patients with inflammatory bowel disease. Alimentary Pharmacology and Therapeutics. 831-838.
  • Vegusdal, Anne; Gjøen, Tor; Berge, Rolf Kristian; Thomassen, Magny Skinlo; Ruyter, Bente. 2005. Effect of 18 : 1n-9, 20 : 5n-3, and 22 : 6n-3 on lipid accumulation and secretion by Atlantic salmon hepatocytes. Lipids. 477-486.
  • Fernø, Johan; Ræder, Maria Therese Barøy; Vik-Mo, Audun Osland; Skrede, Silje; Glambek, Marte; Tronstad, Karl Johan; Breilid, Harald; Løvlie, Roger; Berge, Rolf Kristian; Stansberg, Christine; Steen, Vidar Martin. 2005. Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action? The Pharmacogenomics Journal. 298-304.
  • Dyrøy, Endre; Yndestad, Arne; Ueland, Thor; Damås, Jan Kristian; Damas, Jan Kristian; Aukrust, Pål; Berge, Rolf Kristian. 2005. Antiinflammatory effects of tetradecylthioacetic acid involve both peroxisome proliferator-activated receptor alpha-dependent and -independent pathways. Arteriosclerosis, Thrombosis and Vascular Biology. 1364-1369.
  • Fredriksen, Jannicke; Ueland, Thor; Dyrøy, E; Halvorsen, Bente; Melby, K; Melbye, L; Skålhegg, Bjørn Steen; Bohov, P; Skorve, Jon; Berge, RK; Aukrust, Pål; Frøland, Stig Sophus. 2004. Lipid-lowering and anti-inflammatory effects of tetradecylthioacetic acid in HIV-infected patients on highly active antiretroviral therapy. European Journal of Clinical Investigation. 709-715.
  • Wergedahl, Hege; Liaset, Bjørn; Gudbrandsen, Oddrun Anita; Lied, Einar; Espe, Marit; Muna, Ziad A; Mørk, Sverre; Berge, Rolf Kristian. 2004. Fish protein hydrolysate reduces plasma total cholesterol, increases the proportion of HDL cholesterol, and lowers acyl-CoA : Cholesterol acyltransferase activity in liver of Zucker rats. Journal of Nutrition. 1320-1327.
  • Waagbø, Rune; Hamre, Kristin; Bjerkås, Ellen; Berge, Rolf Kristian; Wathne, Einar; Lie, Ø; Torstensen, Bente. 2003. Cataract formation in Atlantic salmon, Salmo salar L., smolt relative to dietary pro- and antioxidants and lipid levels. Journal of Fish Diseases. 213-229.
  • Madsen, Lars; Guerre-Millo, Michele; Flindt, Esben N.; Berge, K.; Tronstad, Karl Johan; Bergene, Elin; Sebokova, Elena; Rustan, Arild; Jensen, J.; Mandrup, Susanne; Kristiansen, K.; Klimes, Ivar; Staels, Bart; Berge, Rolf Kristian. 2002. Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance. Journal of Lipid Research. 742-750.
  • Halvorsen, Bente; Rustan, Arild; Madsen, Lars; Reseland, Janne Elin; Berge, Rolf Kristian; Sletnes, P.; Christiansen, Erling N. 2001. Effect of long-chain n-3 and mono-unsaturated fatty acids on fatty acid oxidation and lipid composition in rats. Annals of Nutrition and Metabolism. 30-37.
  • Müller, F.; Svardal, A.M.; Nordøy, I.; Berge, Rolf Kristian; Aukrust, P.; Frøland, S. S. 2000. Virological and immunological effects of antioxidant treatment in patients with HIV infection. European Journal of Clinical Investigation. 905-914.
  • Müller, F.; Svardal, A.M.; Nordøy, I.; Berge, Rolf Kristian; Aukrust, P.; Frøland, S. S. 2000. Virological and immunological effects of antioxidant treatment in patients with HIV infection. European Journal of Clinical Investigation. 905-914.
  • Muna, Ziad A.; Bolann, Bjørn Johan; Chen, Xin; Songstad, Jon; Berge, Rolf Kristian. 2000. Tetradecylthioacetic acid and tetradecylselenoacetic acid inhibit lipid eroxidation and interact with superoxide radical. Free Radical Biology & Medicine. 1068-1078.
  • Totland, Geir Kåre; Madsen, Lise; Klementsen, Beate; Vaagenes, Hege; Kryvi, Harald; Frøyland, Livar; Hexeberg, Sofie; Berge, Rolf Kristian. 2000. Proliferation of mitochondria and gene expression of carnitine palmitoyltransferase and fatty acyl-CoA oxidase in rat skeletal muscle, heart and liver by hypolipidemic fatty acids. Biology of the Cell. 317-329.
  • Doudin, K.; Berge, Rolf Kristian; Frøystein, Nils Åge; Songstad, Jon. 2000. Preparation and NMR studies of 3-selenaheptadecanoic and 4-selenaoctadecanoic acid, RSe(CH2)nC(O)OH (R = -C14H29, n = 1 and 2), and their methyl esters. Journal of the Chemical Society. Perkin Transactions 2 (2001). 723-729.
  • Guerre-Millo, Michèle; Gervois, Phillippe; Raspé, Eric; Madsen, Lise; Poulain, Philippe; Derudas, Bruno; Herbert, Jean-Marc; Winegar, Deborah A.; Willson, Timothy M.; Fruchart, Jean-Charles; Berge, Rolf Kristian; Staels, Bart. 2000. Peroxisome Proliferator-activated Receptor a Activators Improve Insulin Sensitivity and Reduce Adipoisty. Journal of Biological Chemistry. 16638-16642.
  • Elholm, Morten; Garras, Alexis; Neve, Søren; Tornehave, Ditte; Lund, Tommy Byskov; Skorve, Jon; Flatmark, Torgeir; Kristiansen, Karsten; Berge, Rolf Kristian. 2000. Long-chain acyl-CoA esters and acyl-CoA binding protein are present in the nucleus of rat liv er cells. Journal of Lipid Research. 538-545.
  • Mansoor, Mohammad A.; Bergmark, Claes; Haswell, Steve; Savage, Ian F.; Evans, Peter H.; Berge, Rolf Kristian; Svardal, Asbjørn; Kristensen, Ole. 2000. Correlation between Plasma Total Homocysteine and Copper in Patients with Peripheral Vascular Disease. Clinical Chemistry. 385-391.
  • Doudin, K.; Berge, Rolf Kristian; Børve, Knut; Skogstad, J.; Törnroos, Karl Wilhelm. 2000. 2,2'-Selenobis(acetic acid), Se(CH2C(o)OH)2: an old compound with a novel structure. Journal of Molecular Structure. 149-161.
  • Rasepé, E.; Madsen, Lise; Lefebvre, M-M.; Leitersdorf, I.; Gelman, L.; Peinado-Onsurbe, J.; Dallongeville, J.; Fruchart, Jean-Charles; Berge, Rolf Kristian; Staels, B. 1999. Modulation of rat liver apolipoprotein gene expression and serum lipid levels by tetradecylthioacetic acid (TTA) via PPARa activation. Journal of Lipid Research. 2099-2110.
  • Madsen, Lise; Garras, Alexis; Asins, Guilermina; Serra, Dolors; Hegardt, Fausto G.; Berge, Rolf Kristian. 1999. Metochondrial 3-Hydroxy-3-Methylglutaryl Coenzyme A Synthase and Carnitine Palmitoyltransferase II as Potential Control sites for Ketogenesis during Mitochondrion and Peroxisome Proliferation. Biochemical Pharmacology. 1011-1019.
  • Vaagenes, Hege; Madsen, Lise; Dyrøy, Endre; Elholm, Morten; Stray-Pedersen, Agnete; Frøyland, Livar; Lie, Øyvind; Berge, Rolf Kristian. 1999. Methylated eicosapentaenoic acid and tetradecylthioacetic acid: Effects on fatty acid metabolism. Biochemical Pharmacology. 1133-1143.
  • Berge, Rolf Kristian; Madsen, Lise; Vaagenes, Hege; Tronstad, Karl Johan; Göttlicher, Martin; Rustan, Arild C. 1999. In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacyllycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation. Biochemical Journal. 191-197.
  • Madsen, Lise; Rustan, Arild C.; Vaagenes, Hege; Berge, Kjetil; Dyrøy, Endre; Berge, Rolf Kristian. 1999. Eicosapentaenoic and docosahexaenoic Acid Affect Mitochondrial and Peroxisomal Fatty Acid Oxidation in Relation to Substrate Preference. Lipids. 951-963.
  • Hennuyer, Nathalie; Poulain, Philippe; Madsen, Lise; Berge, Rolf Kristian; Houdebine, Louis-Marie; Branellec, Didier; Fruchart, Jean-Charles; Fiévet, Catherine; Duverger, Nicolas; Staels, Bart. 1999. Beneficial Effects of Fibrates on Apolipoprotein A-I Metabolism Occur Independently of Any Peroxisome Proliferative Response. Circulation. 2445-2451.
  • Madsen, Lise; Berge, Rolf Kristian. 1999. 3-Thia Fatty Acid Treatment, in Contrast to Eicosapentaenoic Acid and Starvation, Induces Gene Expression of Carnitine Palmitoyltransferase-II in Rat Liver. Lipids. 447-456.
  • Hamre, K.; Berge, Rolf Kristian; Lie, Ø. 1998. Turnover of _a-, _g-, and _b-tocopherol and distribution in subcellular and lipoprotein fraction indicate presence of an hepatic tocopherol binding protein in Atlantic salmon (<i>Salmo salar L</i>). Fish Physiology & Biochemistry. 71-83.
  • Willumsen, Nina; Vaagenes, Hege; Holmsen, Holm A; Berge, Rolf Kristian. 1998. On the effect of 2-deuterium- and 2-methyl-eicosapentaenoic acid derivatives on triglycerides, peroxisomal beta-oxidation and platelet aggregation in rats. Biochimica et Biophysica Acta. 193-203.
  • Willumsen, N.; Vaagenes, Hege; Holmsen, Holm A; Berge, Rolf Kristian. 1998. On the effect of 2-deuterium and 2-methyl-eicosapentaenoic acid derivatives on triglycerides, peroxisomal _b-oxidation and platelet aggregation in rats. Biochimica et Biophysica Acta. 193-203.
  • Hansen, J. B.; Berge, Rolf Kristian; Nordøy, A.; Bønaa, K. H. 1998. Lipid peroxidation of isolated chylomicrons and oxidative status in plasma after prolonged intake of highly purified eicosapentaenoic (EPA) or docosahecaenoic (DHA) acids. Lipids. 1123-1129.
  • Berntsen, Hildegunn; Ekse, Dagfinn; Netteland, Bjørn; Berge, Rolf Kristian; Svardal, Asbjørn; Johannessen, Dag Clement; Lønning, Per Eystein. 1998. Influence of treatment with aminoglutethimide on plasma and red-blood-cell gluthatione status in breast cancer patients. Cancer Chemotherapy and Pharmacology. 46-52.
  • Vaagenes, Hege; Muna, Ziad A.; Madsen, Lise; Berge, Rolf Kristian. 1998. Hypolipidemic n-3 fatty acids increases the antioxidant defence system to inhibit increased plasma and LDL lipid peroxidation. Lipids. 1131-1137.
  • Søvik, Oddmund; Månsson, J-E; Monsen, A.-L. Bjørke ; Jellum, Egil; Berge, Rolf Kristian. 1998. Generalized peroxisomal disorder in male twins: Fatty acid composition of serum lipids and response to n-3 fatty acids. Journal of Inherited Metabolic Disease. 662-670.
  • Søvik, Oddmund; Månsson, J. E.; Bjørke Monsen, Anne Lise; Jellum, E.; Berge, Rolf Kristian. 1998. Generalized peroxisomal disorder in male twins: Fatty acid composition of serum lipids and response to n-3 fatty acids. Journal of Inherited Metabolic Disease. 662-670.
  • Søvik, Oddmund; Månsson, J. E.; Bjørke Monsen, Anne Lise; Jellum, E.; Berge, Rolf Kristian. 1998. Generalized peroxisomal disorder in male twins: Fatty acid composition of serum lipids and response to n -3 fatty acids. Journal of Inherited Metabolic Disease. 662-670.
  • Nordøy, A.; Bønaa, K. H.; Nilsen, H.; Berge, Rolf Kristian; Hansen, J. B.; Ingebretsen, O. C. 1998. Effects of Simvastatin and omega-3 fatty acids on plasma lipoproteins and lipid peroxidation in patients with combined hyperlipidaemia. Journal of Internal Medicine. 163-170.
  • Madsen, Lise; Frøyland, Livar; Dyrøy, Endre; Helland, Kari; Berge, Rolf Kristian. 1998. Docosahexaenoic and eicosapentaenoic acids are differently metabolized in rat liver during mitochondria and peroxisome proliferation. Journal of Lipid Research. 583-593.
  • Fiskerstrand, T.; Riedel, Bettina; Ueland, Per Magne; Seetharam, B.; Pezacka, E. H.; Gulati, S.; Bose, S.; Banerjee, R.; Berge, Rolf Kristian; Refsum, Helga. 1998. Disruption of a regulatory system involving cobalamin distribution and function in a methionine-dependent human glioma cell line. Journal of Biological Chemistry. 20180-20184.
  • Fiskerstrand, T.; Reidel, B.; Ueland, Per Magne; Seetharam, B.; Pezacka, E.; Gulati, S.; Bose, S.; Banerjee, R.; Berge, Rolf Kristian; Refsum, H. 1998. Disruption of a Regulatory system Involving Cobalamin distribution and Function in a Methionine-dependent Human glioma Cell Line. Journal of Biological Chemistry. 20180-20184.
  • Frøyland, Livar; Madsen, Lise; Echoff, K. M.; Lie, Ø; Berge, Rolf Kristian. 1998. Carnitine Palmitloyltransferase I, Carnitine Palmityltransferase II, and Acyl-CoA Oxidase Activities in Atlantic Salmon (<i>Salmo slar</i>). Lipids. 923-930.
  • Vaagenes, Hege; Madsen, Lise; Asiedu, D.; Lillehaug, Johan; Berge, Rolf Kristian. 1998. Acute modulation of genes encoding peroxisomal and mitochondrial _b-oxidation enzymes by 3-thia fatty acids. Biochemical Pharmacology. 1571-1582.
  • Hamre, K.; Waagbø, Rune; Berge, Rolf Kristian; Lie, Ø. 1997. Vitamins C and E interact in juvenile Atlantic salmon (Salmo salar, L). Free Radical Biology & Medicine. 137-149.
  • Madsen, Lise; Frøyland, Livar; Grav, H.J; Berge, Rolf Kristian. 1997. Up-regulated _D(9)-desaturase gene expression by hypolipidemic peroxisome-proliferating fatty acids results in increased oleic acid content in liver and VLDL: Accumulation of a _D(9)-desaturated metabolite of tetradecylthioacetic acid. Journal of Lipid Research. 554-563.
  • Muna, Ziad A.; Doudin, K.; Songstad, Jon; Ulvik, Rune Johan; Berge, Rolf Kristian. 1997. Tetradecylthioacetic acid inhibits the oxidative modification of low density lipoprotein and 8-hydroxydeoxyguanosine formation in vitro. Arteriosclerosis, Thrombosis and Vascular Biology. 3255-3262.
  • Muna, Ziad A.; Doudin, K.; Songstad, Jon; Ulvik, Rune Johan; Berge, Rolf Kristian. 1997. Tetradecylthioacetic acid inhibits the oxidative modification of low density lipoprotein and 8-hydroxydeoxyguanosine formation in vitro. Arteriosclerosis, Thrombosis and Vascular Biology. 3255-3262.
  • Ziad, Muna A.; Doudin, K.; Songstad, Jon; Ulvik, Rune Johan; Berge, Rolf Kristian. 1997. Tetradecylthioacetic Acid Inibits the Oxidative Modification of Low Density Lipoprotein and 8-Hydroxydeoxyguanosine formation in Vitro. Arteriosclerosis, Thrombosis and Vascular Biology.
  • Garras, A.; Elholm, M.; Sleboda, J.; Frøyland, H.; Osmundsen, H.; Berge, Rolf Kristian. 1997. On the effects of thia fatty acid analogues on hydrolases involved in the degradation of metabolisable and non-metabolisable acyl-CoA esters. Xenobiotica. 197-202.
  • Frøyland, Livar; Madsen, Lise; Vaagenes, Hege; Totland, Geir Kåre; Auwerx, J.; Kryvi, Harald; Staels, B; Berge, Rolf Kristian. 1997. Mitochondrion is the principal target for nutritional and pharmacological control of triglyceride metabolism. Journal of Lipid Research. 183-190.
  • Frøyland, Livar; Madsen, Lise; Vaagenes, H; Totland, Geir Kåre; Auwerx, J; Kryvi, Harald; Staels, B; Berge, Rolf Kristian. 1997. Mitochondrion is the principal target for nutitional and pharmacological control of triglyceride metabolism. Journal of Lipid Research. 183-190.
  • Frøyland, Livar; Vaagenes, Hege; Asiedu, D.K.; Garras, Alexis; Lie, Ø; Berge, Rolf Kristian. 1997. Hypotriacylglycerolemic component of fish oil. Prostaglandins, Leukotrienes and Essential Fatty Acids. 387-388.
  • Willumsen, Nina; Vaagenes, H.; Rustan, A.C.; Grav, H.; Lundquist, M.; Skattebøl, L.; Songstad, Jon; Berge, Rolf Kristian. 1997. Enhanced hepatic faty acid oxidation and unpregulated carnitiue palmitoyl-transferance II gene expression by methyl 3-tharoctadeca6,9,12,15 - tetraenoate in rats. Journal of Lipid Mediators and Cell Signalling. 115-134.
  • Willumsen, Nina; Vaagenes, H.; Rustan, A.C.; Grav, H.; Lundquist, M.; Skattebøl, L.; Songstad, Jon; Berge, Rolf Kristian. 1997. Enhanced hepatic fatty acid oxidation and unpregulated carnitinu palmitoyl-transferase II gene expression by methyl 3-tharoctadeca6,9,12,15 - tetraenoate in rats. Journal of Lipid Mediators and Cell Signalling. 115-134.
  • Aukrust, P.; Berge, Rolf Kristian; Müller, F.; Ueland, Per Magne; Svardal, A.M.; Frøland, S.S. 1997. Elevated plasma levels of reduced homocysteine in common variable immunodeficiency - a marker of enhanced oxidative stress. European Journal of Clinical Investigation. 723-730.
  • Aukrust, P.; Berge, Rolf Kristian; Müller, F.; Ueland, Per Magne; Svardal, A.M.; Frøland, S.S. 1997. Elevated plasma levels of reduced homocysteine in common variable immunodeficiency - a marker of enhanced oxidative stress. European Journal of Clinical Investigation. 730-790.
  • Farzaad, A.D.; Frøyland, Livar; Thorsen, Thor Elias; Aakvaag, Asbjørn; Berge, Rolf Kristian. 1997. Eikcosapentaenoic acid and sulphur substituted fatty acid analogues inhibit the proliferation of human breast cancer cells in culture. Breast Cancer Research and Treatment. 229-239.
  • Frøyland, Livar; Madsen, Lise; Sjursen, W.; Garras, Alexis; Lie, Ø.; Songstad, Jon; Rustan, A. C.; Berge, Rolf Kristian. 1997. Effect of 3-thia fatty acids on the lipid composition of rat liver, lipoproteins, and heart. Journal of Lipid Research. 1522-1534.
  • Helleland, Charlotte; Eiane, S.A.; Berge, Rolf Kristian; Holmsen, Holm A; Lillehaug, Johan. 1997. 1-@(Carboxymethylthio@)-tetradecane attenuates PDGF- and TPA-induced c-fos mRNA expression and increases the formation of phosphatidylethanolamine with a shift from less to more polar molecular species in C3H/10 1/2 mouse fibroblasts. Experimental Cell Research. 330-340.
  • Helleland, Charlotte; Eiane, S.A.; Berge, Rolf Kristian; Holmsen, Holm A; Lillehaug, Johan. 1997. 1-@(Carboxymethylthio@)-tetradecane attenuates PDGF- and TPA-induced c-fos mRNA expression and increases the formation of phosphatidylethanolamine with a shift from less to more polar molecular species in C3H/10 1/2 mouse fibroblasts. Experimental Cell Research. 330-340.
  • Asiedu, D. K.; Frøyland, Livar; Vaagenes, H.; Lie, Ø.; Demoz, A.; Berge, Rolf Kristian. 1996. Long-term effect of tetradecylthioacetic acid: a study on lipid profile and fatty acid composition and oxidation in different rat organs. Biochimica et Biophysica Acta. 86-96.
  • Muller, Fredrik; Svardal, Asbjørn M.; Aukrust, Pål; Berge, Rolf Kristian; Ueland, Per Magne; Frøland, Stig Sophus. 1996. Elevated plasma concentration of reduced homocysteine in patients with human immunodeficiency virus infection. American Journal of Clinical Nutrition. 242-248.
  • Willumsen, N.; Vaagenes, H; Lie, Ø.; Berge, Rolf Kristian. 1996. Eicosapentaenoic acid, but not docosahexaenoic acid, increases mitochondrial fatty acid oxidation and upregulates 2,4-dienoyl-CoA reductase gene expression in rats. Lipids. 579-592.
  • Frøyland, Livar; Vaagenes, H.; Asiedu, D. K.; Garras, A.; Lie, Ø.; Berge, Rolf Kristian; Farstad, Marit; Søreide, Odd. 1996. Chronic administration of eicosapentaenoic acid and docosahexaenoic acid as ethyl esters reduced plasma cholesterol and changed fatty acid composition in rat blood and organs. Lipids. 169-178.
  • Frøyland, Livar; Helland, Knut; Totland, Geir Kåre; Kryvi, Harald; Berge, Rolf Kristian. 1996. A hypolipidemic peroxisome proliferating fatty acid induces polydispersity of rat liver mitochondria. Biology of the Cell. 105-112.
  • Frøyland, Livar; Berge, Rolf Kristian. 1996. 3-Thia fettsyrer - et nytt lipidsenkende legemiddel? NBS-nytt. 6-11.
  • Skorve, Jon; Vaagenes, H.; Rosendal, J.; Knudsen, John Chr; Lillehaug, Johan; Berge, Rolf Kristian. 1995. Fatty acid-CoA oxidase activity is induced before long-chain acyl-CoA hydrolase activity and acyl-CoA binding protein in liver of rats treated with peroxisome proliferating 3-thia fatty acids. Xenobiotica. 1181-1194.
  • Hexeberg, S; Willumsen, N; Berge, Rolf Kristian. 1995. Eicosapentaenoic acid causes transient accumalation of lipids in rat myocardium. Biochimica et Biophysica Acta. 341-345.
  • Asiedu, D. K.; Berge, Rolf Kristian. 1994. On the mechanism of 3-thia fatty acids. Lipid-forum.
  • Demoz, A.; Asiedu, D. K.; Lie, Ø.; Berge, Rolf Kristian. 1994. Modulation of plasma and hepatic oxidative status and changes in plasma lipid profile by n-3 (EPA and DHA), n-6 (corn-oil) and a 3-thia fatty acid in rats. Biochimica et biophysica acta. Specialized section on nucleic acids and related subjects. 238-244.
  • Berge, Rolf Kristian; Hvattum, E. 1994. Impact of cytochrome P450 system on lipoprotein metabolism. Effect of abnormal fatty acids (3-thia fatty acid). Pharmacology and Therapeutics. 345-383.
  • Grav, H. J.; Asiedu, D. K.; Berge, Rolf Kristian. 1994. Gas chromatographic measurement of 3- and 4-thia fatty acids incorporated into various classes of rat liver lipids during feeding experiments. Journal of chromatography. B. 1-10.
  • Abdi-Dezfuli, F.; Berge, Rolf Kristian; Rasmussen, M.; Thorsen, Thor Elias; Aakvaag, Asbjørn. 1994. Effects of saturated and polyunsaturated fatty acids and their 3-thia fatty acid analougues on MCF-7 breast cancer cell growth. Annals of the New York Academy of Sciences. 306-309.
  • Hexeberg, S.; Willumsen, N.; Berge, Rolf Kristian. 1994. Docosahexaenoic induced lipid accumulation in myocardial cells of rats. Scandinavian Journal of Clinical and Laboratory Investigation. 665-671.
  • Demoz, A.; Vaagenes, H.; Aareæther, N.; Hvattum, E.; Skorve, Jon; Goettlicher, M.; Lillehaug, Johan; Gibson, G. G.; Gustafsson, J. Å.; Hood, S.; Berge, Rolf Kristian. 1994. Coordinate induction of hepatic fatty acyl-CoA oxidase and P450A1 in rat after activation of the peroxisome proliferator-activated receptor (PPAR) by sulphur-substituted fatty acid analogues. Xenobiotica. 943-954.
  • Demoz, A.; Vaagenes, H.; Aareæther, N.; Hvattum, E.; Skorve, Jon; Goettlicher, M.; Lillehaug, Johan; Gibson, G. G.; Gustafsson, J. Å.; Hood, S.; Berge, Rolf Kristian. 1994. Coordinate induction of hepatic fatty acyl-CoA oxidase and P450A1 in rat after activation of the peroxisome proliferator-activated receptor (PPAR) by sulphur-substituted fatty acid analogues. Xenobiotica. 943-954.
  • Hexeberg, S; Hexeberg, E; Willumsen, N; Berge, Rolf Kristian. 1994. A study on lipid metabolism in heart and liver of cholesterol- and pectin-fed rats. British Journal of Nutrition. 181-192.
  • Hexeberg, S.; Hexeberg, E.; Willumsen, N.; Berge, Rolf Kristian. 1994. A study on lipid metabolism in heart and liver of cholesterol and pectin fed rats. British Journal of Nutrition. 181-192.
  • Berge, Rolf Kristian. 1993. The triglyceride-lowering effect on omega-3 fatty acids. Is it all in eicosapentaenoc acid. Omega-3 News. 5-8.
  • Willumsen, N.; Skorve, Jon; Hexeberg, S.; Berge, Rolf Kristian. 1993. The hypotriglyceridemic effect of eicosapentaenoic acid in rats is reflected in increased mitochondrial fatty acid oxidation followed by diminished lipogenesis. Lipids. 683-690.
  • Shurbaji, A.; Skorve, Jon; Berge, Rolf Kristian; Rudling, M.; Bjørkheim, I.; Berglund, L. 1993. The effect of 3-thiadicarboxcylic acid on lipid metabolism in experimental nephrosis. Arteriosclerosis and thrombosis. 1580-1586.
  • Gøttlicher, M.; Demoz, A.; Svensson, D.; Gustafsson, J. Å.; Berge, Rolf Kristian. 1993. Structural and metaboli requirements for activators of the peroxisome proliferator activated receptor (PPAR). Biochemical Pharmacology. 36-43.
  • Demoz, A.; Svardal, A.; Berge, Rolf Kristian. 1993. Relationship between peroxisomes proliferating sulfur substituted fatty acid analogues, heatic lipid peroxidation and hydrogen peroxide metabolism. Biochemical Pharmacology. 257-259.
  • Tollef, P.; Strømstedt, M.; Frøyland, Livar; Berge, Rolf Kristian; Gustafsson, J. A. 1993. Pretranslational regulation of cytochrome P-450 4A1 by free fatty acids in primary cultures of rat hepatocytes. Journal of Lipid Research. 1758-1791.
  • Skorve, Jon; Al-Shurbaji, A.; Asiedu, D. K.; Bjørkheim, I.; Berglund, L.; Berge, Rolf Kristian. 1993. On the mechanism of the hypolipidemic effect on sulfur-substituted hexadecanediotic (3-thiadicarboxylic acid) in normolipidemic rats. Journal of Lipid Research. 1177-1185.
  • Skorve, Jon; Svardal, Asbjørn; Mansoor, M. A.; Berge, Rolf Kristian. 1993. Modulation of phosphatidylcholine biosynthesis by peroxisomal proliferating fatty acid analogs. Lipids. 795-801.
  • Skorve, Jon; Berge, Rolf Kristian. 1993. Hypolipidemic effect of sulfur-substitutet fatty acid analogues in rats fed a high carbohydrate diet. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 175-183.
  • Demoz, A.; Willumsen, N.; Berge, Rolf Kristian. 1993. Eicosapentaenoic acid at hypotriglyceridemic dose enhances the hepatic antioxidant defense in mice. Lipids. 968-971.
  • Asiedu, D. K.; Skorve, Jon; Willumsen, N.; Demoz, A.; Berge, Rolf Kristian. 1993. Early affects on mitocondrial and peroxisomal beta-oxidation by the hypolipidemic 3-thia fatty acid in rat livers. Biochimica et Biophysica Acta. 73-76.
  • Willumsen, N.; Hexeberg, S.; Skorve, Jon; Lundquist, M.; Berge, Rolf Kristian. 1993. Docosahexaenoic Acid Shows no Triglyceride-Lowering Effects, but increases the Peroxisomal Fatty Acid Oxidation in Liver of Rats. Journal of Lipid Research. 13-22.
  • Hexeberg, S.; Willumsen, N.; Rotevatn, S.; Hexeberg, E.; Berge, Rolf Kristian. 1993. Cholesterol induced lipid accumulation in myocardial cells of rats. Cardiovascular Research (CVR). 442-446.
  • Hexeberg, S.; Willumsen, N.; Rotevatn, S.; Hexeberg, E.; Berge, Rolf Kristian. 1993. Cholesterol induced lipid accumulation in myocardial cells of rats. Cardiovascular Research (CVR). 442-446.
  • Karwinski, W.; Ulvik, Rune Johan; Farstad, Marit; Svardal, Asbjørn; Berge, Rolf Kristian; Søreide, Odd. 1993. Allupurinol does not affect the concentration of endogenous glutathione in liver cells in rats after 60 min of normothermic liver ischemia. European Journal of Surgery. 355-359.
  • Farstad, Marit; Bakken, A. M.; Berge, Rolf Kristian. 1992. The activity and subcellular distribution of the peroxisomal enzyme acyl-CoA oxidase in human bloodplatelets. Biochemical Journal. 829-831.
  • Asiedu, D.; Skorve, Jon; Demoz, A.; Willumsen, N.; Berge, Rolf Kristian. 1992. Relationship between translocation of long-chain acyl-CoA hydrolase, phosphatidate phosphohydrolase and CTP:Phosphocholine cytidylyltransferase and the synthesis of triglycerides and phosphatidylcholine in rat liver. Lipids. 241-147.
  • Asiedu, D. K.; Skorve, Jon; Demoz, A.; Willumsen, N.; Berge, Rolf Kristian. 1992. Relationship between translocation of long-chain Acyl-CoA hydrolase, phosphatidate phosphohydrolase and CTP: phosphocholine cytidyltransferase and the synthesis of triglycerides and phosphatidylcholine in rat liver. Lipids. 241-247.
  • Demoz, A.; Willumsen, N.; Berge, Rolf Kristian. 1992. Eicosapentaenoic acid at hypotriglyceridemic dose enhances the hepatic antiocidant defense in mice. Lipids. 968-972.
  • Skorve, Jon; Asiedu, D.; Solbakken, M.; Gjestdal, M.; Songstad, Jon; Berge, Rolf Kristian. 1992. Comparative effects of oxygen and sulfur-substituted fatty acids on serum lipids and mitochondrial and peroxisomal fatty acid-oxidation in rat. Biochemical Pharmacology. 815-822.
  • Skorve, Jon; Asiedu, D.; Solbakken, M.; Gjestdal, J.; Berge, Rolf Kristian; Sognstad, J. 1992. Camparative effects of oxygen and sulfur-substituted fatty acids on serum lipids and mitochondrial and peroxisomal fatty acid oxidation in rat. Biochemical Pharmacology. 815-822.
  • Aarsland, A.; Berge, Rolf Kristian. 1991. Peroxsisome proliferating sulfur - and oxysubstituted fatty acid analogues are activated to coenzyme-A thioesters. Biochemical Pharmacology. 53-61.
  • Axelson, S. E. H.; Osmundsen, H.; Berge, Rolf Kristian. 1990. The presence of acyl-CoA hydrolase in rat brown-adipose-tissue peroxisomes. Biochemical Journal. 41-46.
  • Aarsland, A.; Berge, Rolf Kristian; Bremer, J.; Aarsæther, Niels. 1990. The hypolipidemic peroxisome proliferating drug bis (carboxymethylthio)-1.10-decane, a dicarboxylic metabolite of tiadenol, is activated to an acyl-coenzyme A thioester. Biochimica et Biophysica Acta. 176-183.
  • Skorve, Jon; Asiedu, D.; Rustan, A. C.; Drevon, C.; Al-Shurbaji, [Mangler fornavn]; Berge, Rolf Kristian. 1990. Regulation of fatty acid oxidation, triglyceride- and phospholipid metabolism by hypolipidemic sulfur-substituted fatty acid and analogues. Journal of Lipid Research. 1627-1635.
  • Aarsland, A.; Lundquist, M.; Børretsen, B.; Berge, Rolf Kristian. 1990. On the effect of peroxisomal _b-oxidation and carnitine palmitoyltransferase activity by eicosapentaenoic acid in liver and hearts from rats. Lipids. 546-549.
  • Kryvi, Harald; Aarsland, A.; Berge, Rolf Kristian. 1990. Morphologic effects of sulfursubstituted fatty acids on rat hepatocytes with special references to proliferation of peroxisomes and mitochondria. Journal of Structural Biology. 257-265.
  • Asiedu, D.; Aarsland, A.; Skorve, R.; Svardal, Asbjørn; Berge, Rolf Kristian. 1990. Fatty acid metabolism in livers of rats treated with hypolipidemic sulphur substituted fatty acid analogues. Role of long-chain acyl-CoA and requirement for stimulated fatty acid oxidation in peroxisomes. Biochimica et Biophysica Acta. 211-221.
  • Aarsæther, Niels; Aarsland, A.; Fosse, R.; Berge, Rolf Kristian. 1990. Effects of the tumor promoter 12-0-tetradecanoylphorbol-13-acetate, on peroxisomal activities and enzyme activities involved in lipid metabolism in liver. Biochimica et Biophysica Acta. 86-93.
  • Hovik, R.; Aarsland, A.; Osmundsen, H.; Bergseth, S.; Bremer, J.; Berge, Rolf Kristian. 1990. Effects of 3- and 4-thia substituted fatty acids on mitochondrial and peroxisomal _b-oxidation. In vivo and in vitro studies. Biochemical Journal. 321-330.
Academic lecture
  • Ahlstrøm, Øystein; Berge, Rolf Kristian; Bjørndal, Bodil; Xue, Chen. 2018. Effect of tetradecylthioacetic acid (TTA) on energy intake and body fat deposition in silver foxes (Vulpes vulpes).
  • Stiksrud, Birgitte; Lorvik, Kristina Berg; Kvale, Dag; Mollnes, Tom Eirik; Ueland, Per Magne; Berge, Rolf Kristian; Trøseid, Marius; Tasken, Kjetil; Dyrhol-Riise, Anne Ma. 2015. Plasma Interferon-inducible Protein 10 Levels, T-cell Activation and Regulation are Increased in HIV Immunological Non-Responders.
  • Khalid, Ahmed Murtaz; Hafstad, Anne Dragøy; Lund, trine; Larsen, Terje; Severson, david lester; Berge, Rolf; Clarke, Kieran; Aasum, Ellen. 2008. Administration of tetradecylthioacetic acid (TTA) in mice accelerates myocardial FA oxidation via increased expression of pparα target genes.
  • Røst, Therese Halvorsen ; Dyrøy, Endre; Pettersen, Reidar J.; Halvorsen, Bente ; Gudbrandsen, Oddrun Anita; Ueland, Thor; Muna, Ziad; Muller, Fredrik; Nordrehaug, Jan Erik; Aukrust, Pål; Berge, Rolf Kristian. 2006. The Antioxidant,Anti-inflammatory and Hypolipidemic Properties of a Seleno-substituted Fatty Acid.
  • Røst, Therese Halvorsen; Mellgren, Gunnar; Berge, Rolf Kristian. 2005. A pan-PPAR ligand induces differential coactivation of PPARs by SRCs and PGC-1.
  • Røst, Therese Halvorsen; Mellgren, Gunnar; Berge, Rolf Kristian. 2004. Tetradecylthioacetic acid induces ligand dependent coactivation of PPARs by PGC-1 and SRC coactivators.
  • Aasum, Ellen; Khalid, Ahmed Murtaz; Gudbrandsen, Oddrun Anita; How, Ole-Jacob; Berge, Rolf; Larsen, Terje. 2004. Different effects of PPAR ligands on cardiac metabolism in mice fed high fat diet.
  • Dyrøy, Endre; Berge, Rolf Kristian. 2004. Decreased TNFα induced endothelial activation in the presence of a new bioactive fatty acid.
  • Arslan, Gülen; Erichsen, Kari; Milde, Anne Marita; Gudbrandsen, Oddrun; Helgeland, Lars; Basu, Simon; Berge, Rolf Kristian; Murison, Robert; Hausken, Trygve; Frøyland, Livar; Berstad, Arnold. 2003. Effects of Omega-3 Fatty Acids on DSS-induced Colitis in Rats.
  • Erichsen, Kari; Gudbrandsen, Oddrun; Arslan, Gülen; Milde, Anne Marita; Helgeland, Lars; Ulvik, Rune Johan; Frøyland, Livar; Berstad, Arnold; Berge, Rolf Kristian; Hausken, Trygve. 2003. Effect of Ferrous Fumarate Supplementation in Dextran Sulfate Sodium Colitis in Rats.
  • Berge, Kjetil; Tronstad, Karl Johan; Nørgaard Flint, Esben; Høj Rasmussen, Thomas; Madsen, Lise; Kristiansen, Karsten; Berge, Rolf Kristian. 2001. Tetradecylthioacetic acid inhibits growth of rat glioma cells ex vivo and in vivo via PPAR-dependent and PPAR-independent pathways.
  • Tronstad, Karl Johan; Berge, Kjetil; Dyrøy, Endre; Madsen, Lise; Berge, Rolf Kristian. 2001. PPAR-activating 3-thia fatty acid influences the growth potential and metabolism in glioma cells.
  • Madsen, Lise; Berge, Rolf Kristian; Guerre-Millo, Michele; Berge, Kjetil; Bergene, Elin; Flindt, Esben N.; Rustan, Arild; Jensen, Jørgen; Sebokova, Elena; Mandrup, Susanne; Kristiansen, Karsten; Klimes, Ivar; Staels, Bart. 2001. Expression of PPARa target genes improve insulin action and reduce adiposity.
  • Holm, Torbjørn; Berge, Rolf Kristian; Andreassen, Arne K.; Ueland, Thor; Kjekshus, John; Simonsen, Svein; Gullestad, Lars; Aukrust, Pål. 2001. Dietary treatment of highly concentrated omega-3 fatty acids increases tumor necrosis factor alpha and reduces antioxidant levels in stable heart transplant recipients.
  • Tronstad, Karl Johan; Gjertsen, Bjorn Tore; Berge, Kjetil; Brustugun, Odd Terje; Døskeland, Stein Ove; Berge, Rolf Kristian. 2001. 3-Thia fatty acid induces mitochondrial alterations and triggers apoptosis in cancer cells.
  • Berge, Rolf Kristian; Madsen, Lise; Guerre-Millo, Michele; Berge, Kjetil; Bergene, Elin; Nørgaard Flint, Esben. 2000. Expression of PPAR alpha target genes improve insulin action and reduce adiposity.
  • Bolann, Bjørn Johan; Chen, Xin; Ulvik, Rune Johan; Berge, Rolf Kristian. 1998. On the antioxidant effect of tetradecylthioacetic acid and tetradecylselenoacetic acid.
  • Tronstad, Karl Johan; Berge, Kjetil; Brustugun, Odd Terje; Bjerkvig, Rolf; Berge, Rolf Kristian. 1998. Metabolic effects of 3-thia fatty acid in cancer cells.
  • Chen, Xin; Bolann, Bjørn Johan; Berge, Rolf Kristian; Ulvik, Rune Johan. 1998. Antioxidant properties of 3-Thia fatty acids.
  • Søvik, Oddmund; Monsen, A. L. B.; Berge, Rolf Kristian; Kryvi, Harald; Jellum, E. 1994. Zellweger-like syndrome: Prolonged survival in male twins during treatment with n-3 fatty acids.
Abstract
  • Rostrup, Espen; Slettom, Grete; Seifert, Reinhard; Berge, Rolf Kristian; Nordrehaug, Jan Erik. 2012. Combined thermal and electrical muscle stimulation reduce visceral fat and improve lipid profile during weight loss. Circulation. E679-E680.
  • Øie, Erik; Ueland, Thor; Dahl, Christen Peder; Bohov, Pavol; Berge, Christ; Yndestad, Arne; Gullestad, Lars; Aukrust, Pål; Berge, Rolf Kristian. 2010. Low circulating eicosatetraenoic acid and high vaccenic acid are associated with disease severity and predict mortality in heart failure. European Heart Journal. 570-570.
  • Khalid, Ahmed Murtaz; Aasum, Ellen; Hafstad, Anne Dragøy; Clarke, K; Berge, Rolf; Larsen, Terje. 2008. TTA is a pan PPAR ligand which markedly stimulates fatty acid oxidation following in vivo administration. Cardiovascular Drugs and Therapy. 142-143.
  • Stunes, Astrid Kamilla; Gustafsson, Björn; Berge, Rolf Kristian; Westbroek, Irene; Reseland, Janne; Syversen, Unni. 2007. The PPAR gamma agonist pioglitazone exaggerates bone loss, while the PPAR alpha agonist fenofibrate maintains BMD and bone architecture in ovarectomized rats. Calcified Tissue International. S40-S40.
  • Erikstein, Bjarte Skoe; Tronstad, Karl Johan; McCormack, Emmet Martin; Schwede, Frank; Berge, Rolf Kristian; Gjertsen, Bjørn Tore. 2007. Synergistic anti-leukemic effect of protein kinase a activator and PPAR7agonist is independent of Bcl-2 status. Blood. 117B-117B.
  • Hafstad, Anne Dragøy; Khalid, Ahmed Murtaz; How, Ole-Jakob; Berge, Rolf; Larsen, Terje; Aasum, Ellen. 2007. In vivo administration of tetradecylthioacetic acid (TTA) in mice causes cardiac inefficiency and reduced post-ischemic ventricular function. Journal of Molecular and Cellular Cardiology.
  • Grimstad, Tore; Hausken, Trygve; Berge, Rolf Kristian; Aarsland, Torbjørn. 2007. Health effects from a regular intake of Atlantic salmon in patients with active ulcerative colitis. Scandinavian Journal of Gastroenterology. 26-26.
  • Aasum, Ellen; Khalid, Ahmed Murtaz; Gudbrandsen, OA; Larsen, Terje; Berge, Rolf. 2006. Indirect and direct effects of PPAR ligands on myocardial metabolism. Journal of Molecular and Cellular Cardiology. 931-932.
  • Ibrahim, Salah Osman; Haraldsen, Heidi Ellis; Miron, Talia; Dysvik, Bjarte; Berge, Rolf Kristian; Vasstrand, Endre N. 2005. Effects of the modified fatty acid tetradecylthioacetic acid (TTA) on an oral cancer progression model. Genomic and proteomic approaches. Oral Oncology. 164-165.
  • Iversen, PO; Sorensen, DR; Berge, Rolf Kristian; Rustan, AC; Drevon, CA. 2005. A sulfur-substituted fatty acid analog improves survival and impairs metastasis in rat models of acute leukemia. Experimental Hematology.
  • Berge, RK; Tronstad, KJ; Gudbrandsen, OA; Berge, K; Wergedahl, H; Grav, Hans J. 2004. Improved insulin sensitivity and reduced adipose tissue mass in relation to mitochondrial function, energy state and PPAR activation. Biochimica et Biophysica Acta - Bioenergetics. 203-203.
  • Dyrøy, Endre; Yndestad, A; Ueland, T; Aukrust, P; Berge, Rolf Kristian. 2004. Decreased TNF alpha induced endothelial activation in the presence of a new bioactive fatty acid. Chemistry and Physics of Lipids. 39-39.
  • Gudbrandsen, Oddrun Anita; Wergedahl, Hege; Berge, Rolf Kristian. 2004. Cholesterol lowering effect of bioactive proteins. Chemistry and Physics of Lipids. 74-74.
Academic literature review
  • Dankel, Simon E Nitter; Staalesen, Vidar; Bjørndal, Bodil; Berge, Rolf Kristian; Mellgren, Gunnar; Burri, Lena. 2011. Tissue-specific effects of bariatric surgery including mitochondrial function. 435245.
  • Burri, Lena; Thoresen, G. Hege; Berge, Rolf Kristian. 2010. The Role of PPAR alpha Activation in Liver and Muscle. 11 pages.

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