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Rolf Kristian Berge's picture

Rolf Kristian Berge

Assistant Professor
  • E-mailrolf.berge@uib.no
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
    5009 Bergen
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • Show author(s) (2017). Serum acylcarnitines and risk of cardiovascular death and acute myocardial infarction in patients with stable angina pectoris. Journal of the American Heart Association (JAHA). 1-28.
  • Show author(s) (2017). Microbiota-dependent metabolite and cardiovascular disease marker trimethylamine-N-oxide (TMAO) is associated with monocyte activation but not platelet function in untreated HIV infection. BMC Infectious Diseases. 1-8.
  • Show author(s) (2017). Increased hepatic mitochondrial FA oxidation reduces plasma and liver TG levels and is associated with regulation of UCPs and APOC-III in rats. Journal of Lipid Research. 1362-1373.
  • Show author(s) (2017). HIV-infected persons with type 2 diabetes show evidence of endothelial dysfunction and increased inflammation. BMC Infectious Diseases. 1-8.
  • Show author(s) (2017). Bariatric surgery reduces fasting total fatty acids and increases n-3 polyunsaturated fatty acids in morbidly obese individuals. Scandinavian Journal of Clinical and Laboratory Investigation. 628-633.
  • Show author(s) (2016). The molecular structure of thio-ether fatty acids influences PPAR-dependent regulation of lipid metabolism. Bioorganic & Medicinal Chemistry. 1191-1203.
  • Show author(s) (2016). The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis. Atherosclerosis. 64-69.
  • Show author(s) (2016). Tetradecylthiopropionic acid induces hepatic mitochondrial dysfunction and steatosis, accompanied by increased plasma homocysteine in mice. Lipids in Health and Disease. 16 pages.
  • Show author(s) (2016). Serum trans fatty acids, asymmetric dimethylarginine and risk of acute myocardial infarction and mortality in patients with suspected coronary heart disease: a prospective cohort study. Lipids in Health and Disease.
  • Show author(s) (2016). Peroxisome Proliferator-Activated Receptor Activation is Associated with Altered Plasma One-Carbon Metabolites and B-Vitamin Status in Rats. Nutrients.
  • Show author(s) (2016). Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice. Scientific Reports.
  • Show author(s) (2016). Microbiota-Dependent Marker TMAO Is Elevated in Silent Ischemia but Is Not Associated with First-Time Myocardial Infarction in HIV Infection. Journal of Acquired Immune Deficiency Syndromes. 130-136.
  • Show author(s) (2016). Microalgae and organic minerals enhance lipid retention efficiency and fillet quality in Atlantic salmon (Salmo salar L.). Aquaculture. 47-57.
  • Show author(s) (2016). Insulin Postconditioning Reduces Infarct Size in the Porcine Heart in a Dose-Dependent Manner. Journal of Cardiovascular Pharmacology and Therapeutics. 179-188.
  • Show author(s) (2016). Genome-wide association analysis identifies variation in Vitamin D receptor and other host factors influencing the gut microbiota. Nature Genetics. 1396-1406.
  • Show author(s) (2016). Elevated trimethylamine-N-oxide (TMAO) is associated with poor prognosis in primary sclerosing cholangitis patients with normal liver function. United European Gastroenterology journal. 532-541.
  • Show author(s) (2016). Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation. Mucosal Immunology.
  • Show author(s) (2015). Three differently generated salmon protein hydrolysates reveal opposite effects on hepatic lipid metabolism in mice fed a high-fat diet. Food Chemistry. 101-110.
  • Show author(s) (2015). Olanzapine depot exposure in male rats: Dose-dependent lipogenic effects without concomitant weight gain. European Neuropsychopharmacology. 923-932.
  • Show author(s) (2015). Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure. Journal of Internal Medicine. 717-726.
  • Show author(s) (2015). Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults - a pilot study. Lipids in Health and Disease. 12 pages.
  • Show author(s) (2015). Fish oil and krill oil differentially modify the liver and brain lipidome when fed to mice. Lipids in Health and Disease.
  • Show author(s) (2015). Antipsychotic-induced metabolic effects in the female rat: Direct comparison between long-acting injections of risperidone and olanzapine. Journal of Psychopharmacology. 1280-1289.
  • Show author(s) (2015). Altered Levels of Fatty Acids and Inflammatory and Metabolic Mediators in Epicardial Adipose Tissue in Patients With Systolic Heart Failure. Journal of Cardiac Failure. 916-923.
  • Show author(s) (2015). A protein extract from chicken reduces plasma homocysteine in rats. Nutrients. 4498-4511.
  • Show author(s) (2015). A phospholipid-protein complex from krill with antioxidative and immunomodulating properties reduced plasma triacylglycerol and hepatic lipogenesis in rats. Marine Drugs. 4375-4397.
  • Show author(s) (2015). A Phospholipid-Protein Complex from Antarctic Krill Reduced Plasma Homocysteine Levels and Increased Plasma Trimethylamine-N-Oxide (TMAO) and Carnitine Levels in Male Wistar Rats. Mar. Drugs. Marine Drugs. 5706-5721.
  • Show author(s) (2014). Olanzapine depot formulation in rat: a step forward in modelling antipsychotic-induced metabolic adverse effects. International Journal of Neuropsychopharmacology. 91-104.
  • Show author(s) (2014). Hypolipidemic effect of dietary water-soluble protein extract from chicken: impact on genes regulating hepatic lipid and bile acid metabolism. European Journal of Nutrition. 193-204.
  • Show author(s) (2014). Hypolipidemic effect of dietary water-soluble protein extract from chicken: impact on genes regulating hepatic lipid and bile acid metabolism. European Journal of Nutrition. 193-204.
  • Show author(s) (2014). High consumption of farmed salmon does not disrupt the steady state of persistent organic pollutants (POP) in human plasma and adipose tissue. Journal of Toxicology and Environmental Health, Part A. 1229-1250.
  • Show author(s) (2014). Effect of combined thermal and electrical muscle stimulation on cardiorespiratory fitness and adipose tissue in obese individuals. European Journal of Preventive Cardiology (EJPC). 1292-1299.
  • Show author(s) (2014). A salmon protein hydrolysate exerts lipid-independent anti-atherosclerotic activity in apoE-deficient mice. PLOS ONE.
  • Show author(s) (2014). A krill powder-diet reduces fatty acid and amino acid catabolism while increasing mitochondrial oxidative phosphorylation, a study of the hepatic transcriptome in mice. Journal of Functional Foods. 623-630.
  • Show author(s) (2013). Proteomics identifies molecular networks affected by tetradecylthioacetic acid and fish oil supplemented diets. Journal of Proteomics. 61-77.
  • Show author(s) (2013). Krill protein hydrolysate reduces plasma triacylglycerol level with concurrent increase in plasma bile acid level and hepatic fatty acid catabolism in high-fat fed mice. The Functional Foods in Health and Disease (FFHD). 428-440.
  • Show author(s) (2013). An immunomodulating fatty acid analogue targeting mitochondria exerts anti-atherosclerotic effect beyond plasma cholesterol-lowering activity in apoE(-/-) mice. PLOS ONE. 14 pages.
  • Show author(s) (2013). A salmon peptide diet alleviates experimental colitis as compared with fish oil. Journal of Nutritional Science (JNS). 1-8.
  • Show author(s) (2013). A fish protein hydrolysate alters fatty acid composition in liver and adipose tissue and increases plasma carnitine levels in a mouse model of chronic inflammation. Lipids in Health and Disease. 11 pages.
  • Show author(s) (2010). Protein kinase A activators and the pan-PPAR agonist tetradecylthioacetic acid elicit synergistic anti-leukaemic effects in AML through CREB. Leukemia Research. 77-84.
  • Show author(s) (2010). Novel phospholipid analogues of pan-PPAR activator tetradecylthioacetic acid are more PPARα selective. Bioorganic & Medicinal Chemistry Letters. 1252-1255 .
  • Show author(s) (2009). Trans-10, cis-12-conjugated linoleic acid reduces the hepatic triacylglycerol content and the leptin mRNA level in adipose tissue in obese Zucker fa/fa rats. British Journal of Nutrition. 803-815.
  • Show author(s) (2009). Tetradecylthioacetic acid attenuates dyslipidaemia in male patients with type 2 diabetes mellitus, possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidation. Diabetes, obesity and metabolism. 304-314.
  • Show author(s) (2009). Increased survival by feeding tetradecylthioacetic acid during a natural outbreak of heart and skeletal muscle inflammation in S0 Atlantic salmon, Salmo salar L. Journal of Fish Diseases. 953-961.
  • Show author(s) (2009). Dietary supplementation of tetradecylthioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed on high-fat diets. Diabetes, obesity and metabolism. 1034-1049.
  • Show author(s) (2009). Dietary supplementation of tetradecylhioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed high fat diets. Diabetes, obesity and metabolism. 1034-1049.
  • Show author(s) (2009). Cardiac peroxisome proliferator-activated receptor-alpha activation causes increased fatty acid oxidation, reducing efficiency and post-ischaemic functional loss. Cardiovascular Research (CVR). 519-526.
  • Show author(s) (2009). A pan-PPAR ligand induces hepatic fatty acid oxidation in PPAR alpha-/- mice possibly through PGC-1 mediated PPAR delta coactivation. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1076-1083.
  • Show author(s) (2009). A complex role of activin A in non-alcoholic fatty liver disease. American Journal of Gastroenterology. 2196-2205.
  • Show author(s) (2008). Tetradecylthioacetic acid prevents the inflammatory response in two-kidney, one-clip hypertension. American Journal of Physiology. Regulatory Integrative and Comparative Physiology. R438-R447.
  • Show author(s) (2008). Tetradecylthioacetic acid downregulates cyclooxygenase 2 in the renal cortex of two-kidney, one-clip hypertensive rats. American Journal of Physiology. Regulatory Integrative and Comparative Physiology. R1866-R1873.
  • Show author(s) (2008). Pharmacology and safety of tetradecylthioacetic acid (TTA): phase-1 study. Journal of Cardiovascular Pharmacology. 410-417.
  • Show author(s) (2008). Improved cognitive development among preterm infants attributable to early supplementation of human milk with docosahexaenoic acid and arachidonic acid. Pediatrics. 1137-1145.
  • Show author(s) (2008). Fenofibrate modulates cardiac and hepatic metabolism and increases ischemic tolerance in diet-induced obese mice. Journal of Molecular and Cellular Cardiology. 201-209.
  • Show author(s) (2008). Dietary single cell protein reduces fatty liver in obese Zucker rats. British Journal of Nutrition. 776-785.
  • Show author(s) (2007). Tetradecylselenoacetic acid, a PPAR ligand with antioxidant, antiinflammatory, and hypolipidemic properties. Arteriosclerosis, Thrombosis and Vascular Biology. 628-634.
  • Show author(s) (2007). Effects of dietary thia fatty acids on lipid composition, morphology and macrophage function of Atlantic salmon (Salmo salar L.) kidney. Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology. 103-111.
  • Show author(s) (2007). Dose-dependent coronary artery intimal thickening after local delivery of the anti-oxidant tetradecylthioacetic acid from stents. Atherosclerosis. e39-e47.
  • Show author(s) (2007). Does the capacity for energy utilization affect the survival of post-smolt Atlantic salmon, Salmo salar L., during natural outbreaks of infectious pancreatic necrosis? Journal of Fish Diseases. 399-409.
  • Show author(s) (2007). Differential effect of tetradecythioacetic acid on the renin-angiotensin system and blood pressure in SHR and 2-kidney, 1-clip hypertension. American Journal of Physiology - Renal, fluid and electrolyte physiology. F839-845.
  • Show author(s) (2006). A bioactively modified fatty acid improves survival and impairs metastasis in preclinical models of acute leukemia. Clinical Cancer Research. 3525-3531.
  • Show author(s) (2005). Oral ferrous fumarate or intravenous iron sucrose for patients with inflammatory bowel disease. Scandinavian Journal of Gastroenterology. 1058-1065.
  • Show author(s) (2005). Influence of high content of dietary soybean oil on quality of large fresh, smoked and frozen Atlantic salmon (Salmo salar). Aquaculture International. 217-231.
  • Show author(s) (2005). In vitro culture of human osteosarcoma cell lines: a comparison of functional characteristics for cell lines cultured in medium without and with fetal calf serum. Journal of Cancer Research and Clinical Oncology. 377-384.
  • Show author(s) (2005). Glucose-induced lipogenesis in pancreatic beta-cells is dependent on SREBP-1. Molecular and Cellular Endocrinology. 94-106.
  • Show author(s) (2005). Effects of ferrous sulphate and non-ionic iron-polymaltose complex on markers of oxidative tissue damage in patients with inflammatory bowel disease. Alimentary Pharmacology and Therapeutics. 831-838.
  • Show author(s) (2005). Effect of 18 : 1n-9, 20 : 5n-3, and 22 : 6n-3 on lipid accumulation and secretion by Atlantic salmon hepatocytes. Lipids. 477-486.
  • Show author(s) (2005). Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action? The Pharmacogenomics Journal. 298-304.
  • Show author(s) (2005). Antiinflammatory effects of tetradecylthioacetic acid involve both peroxisome proliferator-activated receptor alpha-dependent and -independent pathways. Arteriosclerosis, Thrombosis and Vascular Biology. 1364-1369.
  • Show author(s) (2003). Cataract formation in Atlantic salmon, Salmo salar L., smolt relative to dietary pro- and antioxidants and lipid levels. Journal of Fish Diseases. 213-229.
  • Show author(s) (2000). Virological and immunological effects of antioxidant treatment in patients with HIV infection. European Journal of Clinical Investigation. 905-914.
  • Show author(s) (2000). Virological and immunological effects of antioxidant treatment in patients with HIV infection. European Journal of Clinical Investigation. 905-914.
  • Show author(s) (2000). Tetradecylthioacetic acid and tetradecylselenoacetic acid inhibit lipid eroxidation and interact with superoxide radical. Free Radical Biology & Medicine. 1068-1078.
  • Show author(s) (2000). Proliferation of mitochondria and gene expression of carnitine palmitoyltransferase and fatty acyl-CoA oxidase in rat skeletal muscle, heart and liver by hypolipidemic fatty acids. Biology of the Cell. 317-329.
  • Show author(s) (2000). Preparation and NMR studies of 3-selenaheptadecanoic and 4-selenaoctadecanoic acid, RSe(CH2)nC(O)OH (R = -C14H29, n = 1 and 2), and their methyl esters. Journal of the Chemical Society. Perkin Transactions 2 (2001). 723-729.
  • Show author(s) (2000). Peroxisome Proliferator-activated Receptor a Activators Improve Insulin Sensitivity and Reduce Adipoisty. Journal of Biological Chemistry. 16638-16642.
  • Show author(s) (2000). Long-chain acyl-CoA esters and acyl-CoA binding protein are present in the nucleus of rat liv er cells. Journal of Lipid Research. 538-545.
  • Show author(s) (2000). Correlation between Plasma Total Homocysteine and Copper in Patients with Peripheral Vascular Disease. Clinical Chemistry. 385-391.
  • Show author(s) (2000). 2,2'-Selenobis(acetic acid), Se(CH2C(o)OH)2: an old compound with a novel structure. Journal of Molecular Structure. 149-161.
  • Show author(s) (1999). Modulation of rat liver apolipoprotein gene expression and serum lipid levels by tetradecylthioacetic acid (TTA) via PPARa activation. Journal of Lipid Research. 2099-2110.
  • Show author(s) (1999). Metochondrial 3-Hydroxy-3-Methylglutaryl Coenzyme A Synthase and Carnitine Palmitoyltransferase II as Potential Control sites for Ketogenesis during Mitochondrion and Peroxisome Proliferation. Biochemical Pharmacology. 1011-1019.
  • Show author(s) (1999). Methylated eicosapentaenoic acid and tetradecylthioacetic acid: Effects on fatty acid metabolism. Biochemical Pharmacology. 1133-1143.
  • Show author(s) (1999). In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacyllycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation. Biochemical Journal. 191-197.
  • Show author(s) (1999). Eicosapentaenoic and docosahexaenoic Acid Affect Mitochondrial and Peroxisomal Fatty Acid Oxidation in Relation to Substrate Preference. Lipids. 951-963.
  • Show author(s) (1999). Beneficial Effects of Fibrates on Apolipoprotein A-I Metabolism Occur Independently of Any Peroxisome Proliferative Response. Circulation. 2445-2451.
  • Show author(s) (1999). 3-Thia Fatty Acid Treatment, in Contrast to Eicosapentaenoic Acid and Starvation, Induces Gene Expression of Carnitine Palmitoyltransferase-II in Rat Liver. Lipids. 447-456.
  • Show author(s) (1998). Turnover of _a-, _g-, and _b-tocopherol and distribution in subcellular and lipoprotein fraction indicate presence of an hepatic tocopherol binding protein in Atlantic salmon (<i>Salmo salar L</i>). Fish Physiology & Biochemistry. 71-83.
  • Show author(s) (1998). On the effect of 2-deuterium- and 2-methyl-eicosapentaenoic acid derivatives on triglycerides, peroxisomal beta-oxidation and platelet aggregation in rats. Biochimica et Biophysica Acta. 193-203.
  • Show author(s) (1998). On the effect of 2-deuterium and 2-methyl-eicosapentaenoic acid derivatives on triglycerides, peroxisomal _b-oxidation and platelet aggregation in rats. Biochimica et Biophysica Acta. 193-203.
  • Show author(s) (1998). Lipid peroxidation of isolated chylomicrons and oxidative status in plasma after prolonged intake of highly purified eicosapentaenoic (EPA) or docosahecaenoic (DHA) acids. Lipids. 1123-1129.
  • Show author(s) (1998). Influence of treatment with aminoglutethimide on plasma and red-blood-cell gluthatione status in breast cancer patients. Cancer Chemotherapy and Pharmacology. 46-52.
  • Show author(s) (1998). Hypolipidemic n-3 fatty acids increases the antioxidant defence system to inhibit increased plasma and LDL lipid peroxidation. Lipids. 1131-1137.
  • Show author(s) (1998). Generalized peroxisomal disorder in male twins: Fatty acid composition of serum lipids and response to n-3 fatty acids. The Journal of Inherited Metabolic Disease (JIMD). 662-670.
  • Show author(s) (1998). Generalized peroxisomal disorder in male twins: Fatty acid composition of serum lipids and response to n -3 fatty acids. The Journal of Inherited Metabolic Disease (JIMD). 662-670.
  • Show author(s) (1998). Effects of Simvastatin and omega-3 fatty acids on plasma lipoproteins and lipid peroxidation in patients with combined hyperlipidaemia. Journal of Internal Medicine. 163-170.
  • Show author(s) (1998). Docosahexaenoic and eicosapentaenoic acids are differently metabolized in rat liver during mitochondria and peroxisome proliferation. Journal of Lipid Research. 583-593.
  • Show author(s) (1998). Disruption of a regulatory system involving cobalamin distribution and function in a methionine-dependent human glioma cell line. Journal of Biological Chemistry. 20180-20184.
  • Show author(s) (1998). Disruption of a Regulatory system Involving Cobalamin distribution and Function in a Methionine-dependent Human glioma Cell Line. Journal of Biological Chemistry. 20180-20184.
  • Show author(s) (1998). Carnitine Palmitloyltransferase I, Carnitine Palmityltransferase II, and Acyl-CoA Oxidase Activities in Atlantic Salmon (<i>Salmo slar</i>). Lipids. 923-930.
  • Show author(s) (1998). Acute modulation of genes encoding peroxisomal and mitochondrial _b-oxidation enzymes by 3-thia fatty acids. Biochemical Pharmacology. 1571-1582.
  • Show author(s) (1997). Vitamins C and E interact in juvenile Atlantic salmon (Salmo salar, L). Free Radical Biology & Medicine. 137-149.
  • Show author(s) (1997). Up-regulated _D(9)-desaturase gene expression by hypolipidemic peroxisome-proliferating fatty acids results in increased oleic acid content in liver and VLDL: Accumulation of a _D(9)-desaturated metabolite of tetradecylthioacetic acid. Journal of Lipid Research. 554-563.
  • Show author(s) (1997). Tetradecylthioacetic acid inhibits the oxidative modification of low density lipoprotein and 8-hydroxydeoxyguanosine formation in vitro. Arteriosclerosis, Thrombosis and Vascular Biology. 3255-3262.
  • Show author(s) (1997). Tetradecylthioacetic acid inhibits the oxidative modification of low density lipoprotein and 8-hydroxydeoxyguanosine formation in vitro. Arteriosclerosis, Thrombosis and Vascular Biology. 3255-3262.
  • Show author(s) (1997). Tetradecylthioacetic Acid Inibits the Oxidative Modification of Low Density Lipoprotein and 8-Hydroxydeoxyguanosine formation in Vitro. Arteriosclerosis, Thrombosis and Vascular Biology.
  • Show author(s) (1997). On the effects of thia fatty acid analogues on hydrolases involved in the degradation of metabolisable and non-metabolisable acyl-CoA esters. Xenobiotica. 197-202.
  • Show author(s) (1997). Mitochondrion is the principal target for nutritional and pharmacological control of triglyceride metabolism. Journal of Lipid Research. 183-190.
  • Show author(s) (1997). Mitochondrion is the principal target for nutitional and pharmacological control of triglyceride metabolism. Journal of Lipid Research. 183-190.
  • Show author(s) (1997). Hypotriacylglycerolemic component of fish oil. Prostaglandins, Leukotrienes and Essential Fatty Acids. 387-388.
  • Show author(s) (1997). Enhanced hepatic faty acid oxidation and unpregulated carnitiue palmitoyl-transferance II gene expression by methyl 3-tharoctadeca6,9,12,15 - tetraenoate in rats. Journal of Lipid Mediators and Cell Signalling. 115-134.
  • Show author(s) (1997). Enhanced hepatic fatty acid oxidation and unpregulated carnitinu palmitoyl-transferase II gene expression by methyl 3-tharoctadeca6,9,12,15 - tetraenoate in rats. Journal of Lipid Mediators and Cell Signalling. 115-134.
  • Show author(s) (1997). Elevated plasma levels of reduced homocysteine in common variable immunodeficiency - a marker of enhanced oxidative stress. European Journal of Clinical Investigation. 723-730.
  • Show author(s) (1997). Elevated plasma levels of reduced homocysteine in common variable immunodeficiency - a marker of enhanced oxidative stress. European Journal of Clinical Investigation. 730-790.
  • Show author(s) (1997). Eikcosapentaenoic acid and sulphur substituted fatty acid analogues inhibit the proliferation of human breast cancer cells in culture. Breast Cancer Research and Treatment. 229-239.
  • Show author(s) (1997). Effect of 3-thia fatty acids on the lipid composition of rat liver, lipoproteins, and heart. Journal of Lipid Research. 1522-1534.
  • Show author(s) (1997). 1-@(Carboxymethylthio@)-tetradecane attenuates PDGF- and TPA-induced c-fos mRNA expression and increases the formation of phosphatidylethanolamine with a shift from less to more polar molecular species in C3H/10 1/2 mouse fibroblasts. Experimental Cell Research. 330-340.
  • Show author(s) (1997). 1-@(Carboxymethylthio@)-tetradecane attenuates PDGF- and TPA-induced c-fos mRNA expression and increases the formation of phosphatidylethanolamine with a shift from less to more polar molecular species in C3H/10 1/2 mouse fibroblasts. Experimental Cell Research. 330-340.
  • Show author(s) (1996). Long-term effect of tetradecylthioacetic acid: a study on lipid profile and fatty acid composition and oxidation in different rat organs. Biochimica et Biophysica Acta. 86-96.
  • Show author(s) (1996). Eicosapentaenoic acid, but not docosahexaenoic acid, increases mitochondrial fatty acid oxidation and upregulates 2,4-dienoyl-CoA reductase gene expression in rats. Lipids. 579-592.
  • Show author(s) (1996). Chronic administration of eicosapentaenoic acid and docosahexaenoic acid as ethyl esters reduced plasma cholesterol and changed fatty acid composition in rat blood and organs. Lipids. 169-178.
  • Show author(s) (1996). A hypolipidemic peroxisome proliferating fatty acid induces polydispersity of rat liver mitochondria. Biology of the Cell. 105-112.
  • Show author(s) (1996). 3-Thia fettsyrer - et nytt lipidsenkende legemiddel? NBS-nytt. 6-11.
  • Show author(s) (1995). Fatty acid-CoA oxidase activity is induced before long-chain acyl-CoA hydrolase activity and acyl-CoA binding protein in liver of rats treated with peroxisome proliferating 3-thia fatty acids. Xenobiotica. 1181-1194.
  • Show author(s) (1995). Eicosapentaenoic acid causes transient accumalation of lipids in rat myocardium. Biochimica et Biophysica Acta. 341-345.
  • Show author(s) (1994). On the mechanism of 3-thia fatty acids. Lipid-forum.
  • Show author(s) (1994). Modulation of plasma and hepatic oxidative status and changes in plasma lipid profile by n-3 (EPA and DHA), n-6 (corn-oil) and a 3-thia fatty acid in rats. Biochimica et biophysica acta. Specialized section on nucleic acids and related subjects. 238-244.
  • Show author(s) (1994). Impact of cytochrome P450 system on lipoprotein metabolism. Effect of abnormal fatty acids (3-thia fatty acid). Pharmacology and Therapeutics. 345-383.
  • Show author(s) (1994). Gas chromatographic measurement of 3- and 4-thia fatty acids incorporated into various classes of rat liver lipids during feeding experiments. Journal of chromatography. B. 1-10.
  • Show author(s) (1994). Effects of saturated and polyunsaturated fatty acids and their 3-thia fatty acid analougues on MCF-7 breast cancer cell growth. Annals of the New York Academy of Sciences. 306-309.
  • Show author(s) (1994). Docosahexaenoic induced lipid accumulation in myocardial cells of rats. Scandinavian Journal of Clinical and Laboratory Investigation. 665-671.
  • Show author(s) (1994). Coordinate induction of hepatic fatty acyl-CoA oxidase and P450A1 in rat after activation of the peroxisome proliferator-activated receptor (PPAR) by sulphur-substituted fatty acid analogues. Xenobiotica. 943-954.
  • Show author(s) (1994). Coordinate induction of hepatic fatty acyl-CoA oxidase and P450A1 in rat after activation of the peroxisome proliferator-activated receptor (PPAR) by sulphur-substituted fatty acid analogues. Xenobiotica. 943-954.
  • Show author(s) (1994). A study on lipid metabolism in heart and liver of cholesterol- and pectin-fed rats. British Journal of Nutrition. 181-192.
  • Show author(s) (1994). A study on lipid metabolism in heart and liver of cholesterol and pectin fed rats. British Journal of Nutrition. 181-192.
  • Show author(s) (1993). The triglyceride-lowering effect on omega-3 fatty acids. Is it all in eicosapentaenoc acid. Omega-3 News. 5-8.
  • Show author(s) (1993). The hypotriglyceridemic effect of eicosapentaenoic acid in rats is reflected in increased mitochondrial fatty acid oxidation followed by diminished lipogenesis. Lipids. 683-690.
  • Show author(s) (1993). The effect of 3-thiadicarboxcylic acid on lipid metabolism in experimental nephrosis. Arteriosclerosis and thrombosis. 1580-1586.
  • Show author(s) (1993). Structural and metaboli requirements for activators of the peroxisome proliferator activated receptor (PPAR). Biochemical Pharmacology. 36-43.
  • Show author(s) (1993). Relationship between peroxisomes proliferating sulfur substituted fatty acid analogues, heatic lipid peroxidation and hydrogen peroxide metabolism. Biochemical Pharmacology. 257-259.
  • Show author(s) (1993). Pretranslational regulation of cytochrome P-450 4A1 by free fatty acids in primary cultures of rat hepatocytes. Journal of Lipid Research. 1758-1791.
  • Show author(s) (1993). On the mechanism of the hypolipidemic effect on sulfur-substituted hexadecanediotic (3-thiadicarboxylic acid) in normolipidemic rats. Journal of Lipid Research. 1177-1185.
  • Show author(s) (1993). Modulation of phosphatidylcholine biosynthesis by peroxisomal proliferating fatty acid analogs. Lipids. 795-801.
  • Show author(s) (1993). Hypolipidemic effect of sulfur-substitutet fatty acid analogues in rats fed a high carbohydrate diet. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 175-183.
  • Show author(s) (1993). Eicosapentaenoic acid at hypotriglyceridemic dose enhances the hepatic antioxidant defense in mice. Lipids. 968-971.
  • Show author(s) (1993). Early affects on mitocondrial and peroxisomal beta-oxidation by the hypolipidemic 3-thia fatty acid in rat livers. Biochimica et Biophysica Acta. 73-76.
  • Show author(s) (1993). Docosahexaenoic Acid Shows no Triglyceride-Lowering Effects, but increases the Peroxisomal Fatty Acid Oxidation in Liver of Rats. Journal of Lipid Research. 13-22.
  • Show author(s) (1993). Cholesterol induced lipid accumulation in myocardial cells of rats. Cardiovascular Research (CVR). 442-446.
  • Show author(s) (1993). Cholesterol induced lipid accumulation in myocardial cells of rats. Cardiovascular Research (CVR). 442-446.
  • Show author(s) (1993). Allupurinol does not affect the concentration of endogenous glutathione in liver cells in rats after 60 min of normothermic liver ischemia. European Journal of Surgery. 355-359.
  • Show author(s) (1992). The activity and subcellular distribution of the peroxisomal enzyme acyl-CoA oxidase in human bloodplatelets. Biochemical Journal. 829-831.
  • Show author(s) (1992). Relationship between translocation of long-chain acyl-CoA hydrolase, phosphatidate phosphohydrolase and CTP:Phosphocholine cytidylyltransferase and the synthesis of triglycerides and phosphatidylcholine in rat liver. Lipids. 241-147.
  • Show author(s) (1992). Relationship between translocation of long-chain Acyl-CoA hydrolase, phosphatidate phosphohydrolase and CTP: phosphocholine cytidyltransferase and the synthesis of triglycerides and phosphatidylcholine in rat liver. Lipids. 241-247.
  • Show author(s) (1992). Eicosapentaenoic acid at hypotriglyceridemic dose enhances the hepatic antiocidant defense in mice. Lipids. 968-972.
  • Show author(s) (1992). Comparative effects of oxygen and sulfur-substituted fatty acids on serum lipids and mitochondrial and peroxisomal fatty acid-oxidation in rat. Biochemical Pharmacology. 815-822.
  • Show author(s) (1992). Camparative effects of oxygen and sulfur-substituted fatty acids on serum lipids and mitochondrial and peroxisomal fatty acid oxidation in rat. Biochemical Pharmacology. 815-822.
  • Show author(s) (1991). Peroxsisome proliferating sulfur - and oxysubstituted fatty acid analogues are activated to coenzyme-A thioesters. Biochemical Pharmacology. 53-61.
  • Show author(s) (1990). The presence of acyl-CoA hydrolase in rat brown-adipose-tissue peroxisomes. Biochemical Journal. 41-46.
  • Show author(s) (1990). The hypolipidemic peroxisome proliferating drug bis (carboxymethylthio)-1.10-decane, a dicarboxylic metabolite of tiadenol, is activated to an acyl-coenzyme A thioester. Biochimica et Biophysica Acta. 176-183.
  • Show author(s) (1990). Regulation of fatty acid oxidation, triglyceride- and phospholipid metabolism by hypolipidemic sulfur-substituted fatty acid and analogues. Journal of Lipid Research. 1627-1635.
  • Show author(s) (1990). On the effect of peroxisomal _b-oxidation and carnitine palmitoyltransferase activity by eicosapentaenoic acid in liver and hearts from rats. Lipids. 546-549.
  • Show author(s) (1990). Morphologic effects of sulfursubstituted fatty acids on rat hepatocytes with special references to proliferation of peroxisomes and mitochondria. Journal of Structural Biology. 257-265.
  • Show author(s) (1990). Fatty acid metabolism in livers of rats treated with hypolipidemic sulphur substituted fatty acid analogues. Role of long-chain acyl-CoA and requirement for stimulated fatty acid oxidation in peroxisomes. Biochimica et Biophysica Acta. 211-221.
  • Show author(s) (1990). Effects of the tumor promoter 12-0-tetradecanoylphorbol-13-acetate, on peroxisomal activities and enzyme activities involved in lipid metabolism in liver. Biochimica et Biophysica Acta. 86-93.
  • Show author(s) (1990). Effects of 3- and 4-thia substituted fatty acids on mitochondrial and peroxisomal _b-oxidation. In vivo and in vitro studies. Biochemical Journal. 321-330.
Academic lecture
  • Show author(s) (2020). Low 3-hydroxyisobutyrate (3-HIB) and high methylmalonic acid (MMA) levels in plasma reflect increased hepatic fatty acid oxidation.
  • Show author(s) (2018). Effect of tetradecylthioacetic acid (TTA) on energy intake and body fat deposition in silver foxes (Vulpes vulpes).
  • Show author(s) (2015). Plasma Interferon-inducible Protein 10 Levels, T-cell Activation and Regulation are Increased in HIV Immunological Non-Responders.
  • Show author(s) (2008). Administration of tetradecylthioacetic acid (TTA) in mice accelerates myocardial FA oxidation via increased expression of pparα target genes.
  • Show author(s) (2006). The Antioxidant,Anti-inflammatory and Hypolipidemic Properties of a Seleno-substituted Fatty Acid.
  • Show author(s) (2005). A pan-PPAR ligand induces differential coactivation of PPARs by SRCs and PGC-1.
  • Show author(s) (2004). Tetradecylthioacetic acid induces ligand dependent coactivation of PPARs by PGC-1 and SRC coactivators.
  • Show author(s) (2004). Different effects of PPAR ligands on cardiac metabolism in mice fed high fat diet.
  • Show author(s) (2004). Decreased TNFα induced endothelial activation in the presence of a new bioactive fatty acid.
  • Show author(s) (2003). Effects of Omega-3 Fatty Acids on DSS-induced Colitis in Rats.
  • Show author(s) (2003). Effect of Ferrous Fumarate Supplementation in Dextran Sulfate Sodium Colitis in Rats.
  • Show author(s) (2001). Tetradecylthioacetic acid inhibits growth of rat glioma cells ex vivo and in vivo via PPAR-dependent and PPAR-independent pathways.
  • Show author(s) (2001). PPAR-activating 3-thia fatty acid influences the growth potential and metabolism in glioma cells.
  • Show author(s) (2001). Expression of PPARa target genes improve insulin action and reduce adiposity.
  • Show author(s) (2001). Dietary treatment of highly concentrated omega-3 fatty acids increases tumor necrosis factor alpha and reduces antioxidant levels in stable heart transplant recipients.
  • Show author(s) (2001). 3-Thia fatty acid induces mitochondrial alterations and triggers apoptosis in cancer cells.
  • Show author(s) (2000). Expression of PPAR alpha target genes improve insulin action and reduce adiposity.
  • Show author(s) (1998). On the antioxidant effect of tetradecylthioacetic acid and tetradecylselenoacetic acid.
  • Show author(s) (1998). Metabolic effects of 3-thia fatty acid in cancer cells.
  • Show author(s) (1998). Antioxidant properties of 3-Thia fatty acids.
  • Show author(s) (1994). Zellweger-like syndrome: Prolonged survival in male twins during treatment with n-3 fatty acids.
Abstract
  • Show author(s) (2012). Combined thermal and electrical muscle stimulation reduce visceral fat and improve lipid profile during weight loss. Circulation. E679-E680.
  • Show author(s) (2010). Low circulating eicosatetraenoic acid and high vaccenic acid are associated with disease severity and predict mortality in heart failure. European Heart Journal. 570-570.
  • Show author(s) (2008). TTA is a pan PPAR ligand which markedly stimulates fatty acid oxidation following in vivo administration. Cardiovascular Drugs and Therapy. 142-143.
  • Show author(s) (2007). The PPAR gamma agonist pioglitazone exaggerates bone loss, while the PPAR alpha agonist fenofibrate maintains BMD and bone architecture in ovarectomized rats. Calcified Tissue International. S40-S40.
  • Show author(s) (2007). Synergistic anti-leukemic effect of protein kinase a activator and PPAR7agonist is independent of Bcl-2 status. Blood. 117B-117B.
  • Show author(s) (2007). In vivo administration of tetradecylthioacetic acid (TTA) in mice causes cardiac inefficiency and reduced post-ischemic ventricular function. Journal of Molecular and Cellular Cardiology.
  • Show author(s) (2007). Health effects from a regular intake of Atlantic salmon in patients with active ulcerative colitis. Scandinavian Journal of Gastroenterology. 26-26.
  • Show author(s) (2006). Indirect and direct effects of PPAR ligands on myocardial metabolism. Journal of Molecular and Cellular Cardiology. 931-932.
  • Show author(s) (2005). Effects of the modified fatty acid tetradecylthioacetic acid (TTA) on an oral cancer progression model. Genomic and proteomic approaches. Oral Oncology. 164-165.
  • Show author(s) (2005). A sulfur-substituted fatty acid analog improves survival and impairs metastasis in rat models of acute leukemia. Experimental Hematology.
  • Show author(s) (2004). Improved insulin sensitivity and reduced adipose tissue mass in relation to mitochondrial function, energy state and PPAR activation. Biochimica et Biophysica Acta - Bioenergetics. 203-203.
  • Show author(s) (2004). Decreased TNF alpha induced endothelial activation in the presence of a new bioactive fatty acid. Chemistry and Physics of Lipids. 39-39.
  • Show author(s) (2004). Cholesterol lowering effect of bioactive proteins. Chemistry and Physics of Lipids. 74-74.
Academic literature review
  • Show author(s) (2011). Tissue-specific effects of bariatric surgery including mitochondrial function. International Journal of Obesity. 435245.
  • Show author(s) (2010). The Role of PPAR alpha Activation in Liver and Muscle. PPAR Research. 11 pages.

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