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  • E-mailRunar.Stokke@uib.no
  • Phone+47 55 58 38 33+47 908 36 074
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    Thormøhlens gate 53 A/B
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    Postboks 7803
    5020 Bergen

My research has a strong focus on deep-sea hydrothermal vent ecosystems.

In spite of the recent technological and analytical advancement in the field of hydrothermal vent research and metagenomics, fundamental and systematic knowledge on the biodiversity of microbial life and their functional role in the unique deep sea vent environments can still be considered as in its infancy and in the exploratory phase. This hampers our ability to evaluate the global ecological role of the hydrothermal vent biota. Since genomic knowledge is still missing for most of the uncultivated lineages in hydrothermal vents, there is a comprehensive knowledge need and potential to discover new microbial lineages with novel and primordial metabolisms, as well as new metabolic inter-dependencies and species interactions. At present, knowledge is also lacking on the encoded capacity of hydrothermal vent microorganisms to produce bioactive compounds to be used in communications between and across trophic levels in the ecosystem, and in turn represent compounds for human benefit.

Integrated studies combining genome-centric metagenomics with metatrascriptomics and high-resolution microscopy is central in my research to infer potential functions of uncultured novel hydrothermal vent microbial lineages, and identifying microbial metabolic interdependencies and co-operations.

 

 

  • Show author(s) 2021. Insights into alginate degradation through the characterization of a thermophilic exolytic alginate lyase. Applied and Environmental Microbiology.
  • Show author(s) 2021. Insights into alginate degradation through the characterization of a thermophilic exolytic alginate lyase. Applied and Environmental Microbiology.
  • Show author(s) 2020. “Candidatus Ethanoperedens,” a thermophilic genus of archaea mediating the anaerobic oxidation of ethane. mBio. 1-18.
  • Show author(s) 2020. Tailoring hydrothermal vent biodiversity towards improved biodiscovery using a novel in-situ enrichment strategy. Frontiers in Microbiology.
  • Show author(s) 2020. Enzyme discovery from the edge of (sequence) space.
  • Show author(s) 2020. Bringing deep-sea enzymes to light.
  • Show author(s) 2019. Production, characterization, and application of an alginate lyase, AMOR_PL7A, from hot vents in the Arctic mid-ocean ridge. Journal of Agricultural and Food Chemistry. 2936-2945.
  • Show author(s) 2019. Identification of key-players in anaerobic alkane oxidation in the diffuse venting Barite Field at the Loki´s castle.
  • Show author(s) 2019. Identification and characterization of a hyperthermophilic GH9 cellulase from the Arctic Mid-Ocean Ridge vent field. PLOS ONE.
  • Show author(s) 2019. Discovery of a Thermostable GH10 Xylanase with Broad Substrate Specificity from the Arctic Mid-Ocean Ridge Vent System. Applied and Environmental Microbiology. 1-16.

More information in national current research information system (CRIStin)

PRINCIPAL INVESTIGATOR:

  • 2021-2024 (Project start 01.06.21)

Research Council of Norway, FRINATEK Researcher Project DeepSeaQuence

Uncovering the metabolic secrets and capacity of Arctic deep-sea hydrothermal vent microbiomes

 

PROJECT PARTNER/COLLABORATOR:

  • 2017-2021

K.G. Jebsen FoundationUiB Centre for Deep-Sea Research (Work Package Leader)

WP6 "Biodiscovery and Bioprospecting" 

Key qualifications:

  • Advanced Bioinformatics
  • Proteomics and Mass spectrometry
  • Metagenomics, metaproteomics and metatranscriptomics
  • Genome assembly and annotation
  • Cultivations of extremophilic microorganisms
  • Protein expression and purification
  • Protein chemistry and structural biology
  • Protein stability

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