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Sean Alexander Bankier's picture

Sean Alexander Bankier

Postdoctoral Fellow
  • E-mailsean.bankier@uib.no
  • Visitor Address
    HIB - Thormøhlens gate 55
    5006 Bergen
  • Postal Address
    Postboks 7803
    5020 Bergen

The focus of my research is to understand how individual genetic variation is related to the prevalence of complex traits and disease within populations. Using multi-omic datasets and causal inference methods, I am particularly interested in the role of the plasma proteome in mediating gene expression signalling between tissues and how this relates to mechanisms of disease.

At UiB, I work on the NFR funded project; Intelligent systems for personalized and precise risk prediction and diagnosis of non-communicable diseases (INTRePID). In this project we aim to create computer methods for risk prediction and diagnosis of non-communicable diseases using multi-omics data, by developing, implementing and validating novel algorithms for structure learning and inference in large-scale, multi-organ causal Bayesian gene networks with applications in cardiovascular medicine. 

Academic article
  • Show author(s) (2024). Single-Cell Gene-Regulatory Networks of Advanced Symptomatic Atherosclerosis. Circulation Research.
  • Show author(s) (2023). Plasma cortisol-linked gene networks in hepatic and adipose tissues implicate corticosteroid-binding globulin in modulating tissue glucocorticoid action and cardiovascular risk. Frontiers in Endocrinology. 12 pages.
  • Show author(s) (2022). eQTLs as causal instruments for the reconstruction of hormone linked gene networks. Frontiers in Endocrinology.

More information in national current research information system (CRIStin)

Avaliable at: https://scholar.google.com/citations?user=tsa5dR8AAAAJ&hl=en