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Simon Steinar Hustad

Professor
  • E-mailSteinar.Hustad@uib.no
  • Phone+47 55 97 46 73
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
  • Postal Address
    Postboks 7804
    5020 Bergen
Journal articles
  • Helland, Thomas; Hagen, Kari Britt; Haugstøyl, Martha Eimstad; Kvaløy, Jan Terje; Lunde, Siri; Lode, Kirsten; Lind, Ragna Anne; Gripsrud, Birgitta Haga; Jonsdottir, Kristin; Gjerde, Jennifer; Bifulco, Ersilia; Hustad, Simon Steinar; Jonassen, Janne; Aas, Turid; Lende, Tone Hoel; Lien, Ernst Asbjørn; Janssen, Emiel; Søiland, Håvard; Mellgren, Gunnar. 2019. Drug monitoring of tamoxifen metabolites predicts vaginal dryness and verifies a low discontinuation rate from the Norwegian Prescription Database. Breast Cancer Research and Treatment. 177: 185-195. doi: 10.1007/s10549-019-05294-w
  • Triebner, Kai; Accordini, Simone; Calciano, Lucia; Johannessen, Ane; Benediktsdóttir, Bryndís; Bifulco, Ersilia; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Garcia-Aymerich, Judith; Gullón Blanco, José Antonio; Heinrich, Joachim; Holm, Mathias; Jarvis, Debbie; Jõgi, Rain; Lindberg, Eva; Martínez-Moratalla, Jesús; Muniozguren Agirre, Nerea; Pin, Isabelle; Probst-Hensch, Nicole; Raherison, Chantal; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Svanes, Cecilie; Hustad, Simon Steinar; Leynaert, Bénédicte; Gomez Real, Francisco. 2019. Exogenous female sex steroids may reduce lung ageing after menopause: A 20-year follow-up study of a general population sample (ECRHS). Maturitas. 120: 29-34. doi: 10.1016/j.maturitas.2018.11.007
  • Helland, Thomas; Henne, Nina; Bifulco, Ersilia; Naume, Bjørn; Borgen, Elin; Kristensen, Vessela N.; Kvaløy, Jan Terje; Lash, Timothy L; Grenaker, Grethe Irene; van Schaik, RHN; Janssen, Emiel; Hustad, Simon Steinar; Lien, Ernst Asbjørn; Mellgren, Gunnar; Søiland, Håvard. 2017. Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients. Breast Cancer Research. 19. doi: 10.1186/s13058-017-0916-4
  • Triebner, Kai; Matulonga, Bobette; Johannessen, Ane; Suske, Sandra; Benediktsdóttir, Bryndís; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Garcia-Aymerich, Judith; Blanco, José Antonio Gullón; Heinrich, Joachim; Holm, Mathias; Jarvis, Deborah; Jõgi, Rain; Lindberg, Eva; Rovira, Jesús Martínez Moratalla; Agirre, Nerea Muniozguren; Pin, Isabelle; Probst-Hensch, Nicole; Puggini, Luca; Raherison, Chantal; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Sunyer, Jordi; Svanes, Cecilie; Hustad, Simon Steinar; Leynaert, Bénédicte; Gomez Real, Francisco. 2017. Menopause is associated with accelerated lung function decline. American Journal of Respiratory and Critical Care Medicine. 195: 1058-1065. doi: 10.1164/rccm.201605-0968OC
  • Ulvik, Arve; Hustad, Simon Steinar; Mccann, Adrian; Midttun, Øivind; Nygård, Ottar; Ueland, Per Magne. 2017. Ratios of one-carbon metabolites are functional markers of B-vitamin status in a Norwegian coronary angiography screening cohort. Journal of Nutrition. 147: 1167-1173. doi: 10.3945/jn.116.244657
  • Triebner, Kai; Johannessen, Ane; Puggini, Luca; Benediktsdóttir, Bryndís; Bertelsen, Randi Jacobsen; Bifulco, Ersilia; Dharmage, Shyamali C.; Dratva, Julia; Franklin, Karl A.; Gislason, Þórarinn; Holm, Mathias; Jarvis, Deborah L.; Leynaert, Bénédicte; Lindberg, Eva; Malinovschi, Andrei; Macsali, Ferenc; Norbäck, Dan; Omenaas, Ernst; Rodríguez, Francisco J.; Saure, Eirunn Waatevik; Schlünssen, Vivi; Sigsgaard, Torben; Skorge, Trude Duelien; Wieslander, Gunilla; Zemp, Elisabeth; Svanes, Cecilie; Hustad, Simon Steinar; Gomez Real, Francisco. 2016. Menopause as a predictor of new-onset asthma: A longitudinal Northern European population study. Journal of Allergy and Clinical Immunology. 137: 50-57.e6. doi: 10.1016/j.jaci.2015.08.019
  • Björnsdottir, Sigridur; Øksnes, Marianne; Isaksson, Magnus; Methlie, Paal; Nilsen, Roy Miodini; Hustad, Simon Steinar; Kämpe, Olle; Hulting, Anna-Lena; Husebye, Eystein Sverre; Løvås, Kristian; Nyström, Thomas; Bensing, Sophie. 2015. Circadian hormone profiles and insulin sensitivity in patients with Addison's disease: a comparison of continuous subcutaneous hydrocortisone infusion with conventional glucocorticoid replacement therapy. Clinical Endocrinology. 83: 28-35. doi: 10.1111/cen.12670
  • Skeie, Eli; Strand, Elin; Pedersen, Eva Ringdal; Bjørndal, Bodil; Bohov, Pavol; Berge, Rolf Kristian; Svingen, Gard Frodahl Tveitevåg; Seifert, Reinhard; Ueland, Per Magne; Midttun, Øivind; Ulvik, Arve; Hustad, Simon Steinar; Drevon, Christian A; Gregory, Jesse F.; Nygård, Ottar. 2015. Circulating B-vitamins and smoking habits are associated with serum polyunsaturated fatty acids in patients with suspected coronary heart disease: A cross-sectional study. PLoS ONE. 10:e0129049. 14 pages. doi: 10.1371/journal.pone.0129049
  • Theofylaktopoulou, Despoina; Ulvik, Arve; Midttun, Øivind; Ueland, Per Magne; Vollset, Stein Emil; Nygård, Ottar; Hustad, Simon Steinar; Tell, Grethe Seppola; Eussen, Simone. 2014. Vitamins B2 and B6 as determinants of kynurenines and related markers of interferon-gamma-mediated immune activation in the community-based Hordaland health study. British Journal of Nutrition. 112: 1065-1072. doi: 10.1017/S0007114514001858
  • Eussen, Simone; Nilsen, Roy Miodini; Midttun, Øivind; Hustad, Simon Steinar; IJssennagger, Noortje; Meyer, Klaus; Fredriksen, Åse; Ulvik, Arve; Ueland, Per Magne; Brennan, Paul; Johansson, Matthias; Bueno-de-Mesquita, Bas; Vineis, Paolo; Chuang, Shu-Chun; Boutron-Ruault, Marie Christine; Dossus, Laure; Perquier, Florence; Overvad, Kim; Teucher, Birgit; Grote, Verena A.; Trichopoulou, Antonia; Adarakis, George; Plada, Maria; Sieri, Sabina; Tumino, Rosario; Santucci de Magistris, Maria; Ros, Martine M.; Peeters, Petra H.M.; Redondo, Maria Luisa; Zamora-Ros, Raul; Chirlaque, Maria-Dolores; Ardanaz, Eva; Sonestedt, Emily; Ericson, Ulrika; Schneede, Jørn; Van Guelpen, Bethany; Wark, Petra A.; Gallo, Valentina; Norat, Teresa; Riboli, Elio; Vollset, Stein Emil. 2013. North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study. British Journal of Nutrition. 110: 363-374. doi: 10.1017/S0007114512004990
  • Methlie, Paal; Hustad, Simon Steinar; Kellmann, Ralph; Almås, Bjørg; Moter-Erichsen, M; Husebye, ES; Løvås, Kristian. 2013. Multisteroid LC-MS/MS assay for glucocorticoids and androgens, and its application in Addison’s disease. Endocrine Connections. 2: 125-136.
  • Hustad, Simon Steinar; Eussen, Simone; Midttun, Øivind; Ulvik, Arve; van de Kant, Puck M; Mørkrid, Lars; Gislefoss, Randi Elin; Ueland, Per Magne. 2012. Kinetic modeling of storage ffects on biomarkers related to B vitamin status and one-carbon metabolism. Clinical Chemistry. 58: 402-410. doi: 10.1373/clinchem.2011.174490
  • Reikvam, Anne-Grete; Hustad, Simon Steinar; Reikvam, Håkon; Apelseth, Torunn Oveland; Nepstad, Ina; Hervig, Tor. 2012. The effects of selective serotonin reuptake inhibitors on platelet function in whole blood and platelet concentrates. Platelets. 23: 299-308. doi: 10.3109/09537104.2011.618852
  • Methlie, Paal; Husebye, Eystein Sverre; Hustad, Simon Steinar; Lien, Ernst Asbjørn; Løvås, Kristian. 2011. Grapefruit juice and licorice increase cortisol availability in patients with Addison's disease. European Journal of Endocrinology. 165: 761-769. doi: 10.1530/EJE-11-0518
  • Christensen, Monika; Lien, Ernst Asbjørn; Hustad, Simon Steinar; Almås, Bjørg. 2010. Seasonal and age-related differences in serum 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D and parathyroid hormone in patients from Western Norway. Scandinavian Journal of Clinical and Laboratory Investigation. 70: 281-286. doi: 10.3109/00365511003797172
  • Eussen, Simone; Vollset, Stein Emil; Hustad, Simon Steinar; Midttun, Øivind; Meyer, Klaus; Fredriksen, Åse; Ueland, Per Magne; Jenab, Mazda; Slimani, Nadia; Boffetta, Paolo; Overvad, Kim; Thorlacius-Ussing, Ole; Tjønneland, A; Olsen, A; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie-Christine; Morois, Sophie; Weikert, Cornelia; Pischon, Tobias; Linseisen, Jakob; Kaaks, Rudolf; Trichopoulou, Antonia; Zilis, Demosthenes; Katsoulis, Michael; Palli, Domenico; Pala, Valeria; Vineis, P; Tumino, Rosario; Panico, Salvatore; Peeters, Petra H.M.; Bueno-De-Mesquita, BH; van Duijnhoven, Fränzel J.B.; Skeie, Guri; Munoz, Zavier; Martinez, Carmen; Dorronsoro, Miren; Ardanaz, Eva; Navarro, Carmen; Rodriguez, Laudina; Van Guelpen, Bethany; Palmqvist, Richard; Manjer, Jonas; Ericson, Ulrika; Bingham, Sheila A; Khaw, Kay-Tee; Norat, Teresa; Riboli, Eilo. 2010. Plasma vitamins B2, B6, and B12, and related genetic variants as predictors of colorectal cancer risk. Cancer Epidemiology, Biomarkers and Prevention. 19: 2549-2561. doi: 10.1158/1055-9965.EPI-10-0407
  • Eussen, Simone; Vollset, Stein Emil; Hustad, Simon Steinar; Midttun, Øivind; Meyer, Klaus; Fredriksen, Åse; Ueland, Per Magne; Jenab, Mazda; Slimani, Nadia; Ferrari, Pietro; Agudo, Antonio; Sala, Núria; Capella, Gabriel; Del Giudice, Giuseppe; Palli, Domenico; Boeing, Heiner; Weikert, Cornelia; Bueno-de-Mesquita, H. Bas; Büchner, Frederike L; Carneiro, Fátima; Berrino, Franco; Vineis, Paolo; Tumino, Rosario; Panico, Salvatore; Berglund, Göran; Manjer, Jonas; Stenling, Roger; Hallmans, Göran; Martinez, Carmen; Arrizola, Larraitz; Barricarte, Aurelio; Navarro, Carmen; Rodriguez, Laudina; Bingham, Sheila; Linseisen, Jakob; Kaaks, Rudolf; Overvad, Kim; Tjønneland, Anne; Peeters, Petra H.M.; Numans, Mattijs E.; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie-Christine; Morois, Sophie; Trichopoulou, Antonia; Lund, Eiliv; Plebani, Mario; Riboli, Elio; González, Carlos A. 2010. Vitamins B2 and B6 and Genetic Polymorphisms Related to One-Carbon Metabolism as Risk Factors for Gastric Adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition. Cancer Epidemiology, Biomarkers and Prevention. 19: 28-38. doi: 10.1158/1055-9965.EPI-08-1096
  • Hannisdal, Rita; Gislefoss, Randi Elin; Grimsrud, Tom K.; Hustad, Simon Steinar; Mørkrid, Lars; Ueland, Per Magne. 2010. Analytical Recovery of Folate and Its Degradation Products in Human Serum Stored at-25 degrees C for up to 29 Years. Journal of Nutrition. 140: 522-526. doi: 10.3945/jn.109.116418
  • Ulvik, Arve; Ebbing, Marta; Hustad, Steinar; Midttun, Øivind; Nygård, Ottar; Vollset, Stein Emil; Bønaa, Kaare Harald; Nordrehaug, Jan Erik; Nilsen, Dennis W; Schirmer, Henrik; Ueland, Per M. 2010. Long- and short-term effects of tobacco smoking on circulating concentrations of B vitamins. Clinical Chemistry. 56: 755-763. doi: 10.1373/clinchem.2009.137513
  • Hannisdal, Rita; Ueland, Per Magne; Eussen, Simone; Svardal, Asbjørn; Hustad, Simon Steinar. 2009. Analytical Recovery of Folate Degradation Products Formed in Human Serum and Plasma at Room Temperature. Journal of Nutrition. 139: 1415-1418. doi: 10.3945/jn.109.105635
  • Midttun, Øivind; Hustad, Simon Steinar; Ueland, Per Magne. 2009. Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry. 23: 1371-1379. doi: 10.1002/rcm.4013
  • Ueland, Per Magne; Hustad, Simon Steinar. 2008. Homocysteine and folate status in an era of folic acid fortification: Balancing benefits, risks, and B-vitamins. Clinical Chemistry. 54: 779-781. doi: 10.1373/clinchem.2008.103218
  • Holm, Pål Ivar; Hustad, Simon Steinar; Ueland, Per Magne; Vollset, Stein Emil; Grotmol, Tom; Schneede, Jørn. 2007. Modulation of the homocysteine-betaine relationship by methylenetetrahydrofolate reductase 677 C-> T genotypes and B-vitamin status in a large-scale epidemiological study. Journal of Clinical Endocrinology and Metabolism. 92: 1535-1541. doi: 10.1210/jc.2006-1471
  • Hustad, Simon Steinar; Midttun, Øivind; Schneede, Jørn; Vollset, Stein Emil; Grotmol, Tom; Ueland, Per Magne. 2007. The methylenetetrahydrofolate reductase 677C -> T polymorphism as a modulator of a B vitamin network with major effects on homocysteine metabolism. American Journal of Human Genetics. 80: 846-855. doi: 10.1086/513520
  • Midttun, Øivind; Hustad, Simon Steinar; Schneede, Jørn; Vollset, Stein Emil; Ueland, Per Magne. 2007. Plasma vitamin B-6 forms and their relation to transsulfuration metabolites in a large, population-based study. American Journal of Clinical Nutrition. 86: 131-138.
  • Ueland, Per Magne; Midttun, Øivind; Windelberg, Amrei; Svardal, Asbjørn; Hannisdal, Rita; Hustad, Simon Steinar. 2007. Review: Quantitative profiling of folate and one-carbon metabolism in large-scale epidemiological studies by mass spectrometry. Clinical Chemistry and Laboratory Medicine. 45: 1737-1745.
  • Ueland, Per Magne; Midttun, Øivind; Windelberg, Amrei; Svardal, Asbjørn; Skålevik, Rita; Hustad, Simon Steinar. 2007. Quantitative profiling of folate and one-carbon metabolism in large-scale epidemiological studies by mass spectrometry. Clinical Chemistry and Laboratory Medicine. 45: 1737-1745. doi: 10.1515/CCLM.2007.339
  • Bjørn Øivind, Midttun; Hustad, Simon Steinar; Solheim, Einar; Schneede, Jørn; Ueland, Per Magne. 2005. Multianalyte quantification of vitamin B-6 and B-2 species in the nanomolar range in human plasma by liquid chromatography - Tandem mass spectrometry. Clinical Chemistry. 51: 1206-1216. doi: 10.1373/clinchem.2005.051169
  • Ueland, Per Magne; Holm, Pål Ivar; Hustad, Simon Steinar. 2005. Betaine: a key modulator of one-carbon metabolism and homocysteine status. Clinical Chemistry and Laboratory Medicine. 43: 1069-1075. doi: 10.1515/CCLM.2005.187
  • Hustad, Simon Steinar; Nedrebø, Bjørn Gunnar; Ueland, Per Magne; Schneede, Jørn; Vollset, Stein Emil; Ulvik, Arve; Lien, Ernst Asbjørn. 2004. Phenotypic expression of the methylenetetrahydrofolate reductase 677C->T polymorphism and flavine cofactor availability in thyroid dysfunction. American Journal of Clinical Nutrition. 80: 1050-1057.
  • Hustad, Simon Steinar; Ueland, PM; Vollset, Stein Emil; Zhang, Y; Bjorke-Monsen, AL; Schneede, Jørn. 2000. Riboflavin as a determinant og plasma total homocysteine: effect modification by the methylenetetrahydrofolate reductase C677T polymorphism. Clinical Chemistry. 46: 1065-1071.
  • Hustad, Simon Steinar; Ueland, Per Magne; Schneede, Jørn. 1999. Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in human plasma by capillary electrophoresis and laser-induced fluorescence detection. Clinical Chemistry. 45: 862-868.
Reports and theses
  • Hustad, Simon Steinar. 2005. Assessment of Riboflavin Status in Humans: Method Development and Clinical Studies. University of Bergen, Section of Pharmacology, Institute of Inernal Medicine. 91 pages.
Book sections
  • Hustad, Simon Steinar; Schneede, Jørn; Ueland, Per Magne. 2004. Riboflavin and methylenetetrahydrofolate reductase. Kap. 6, pages 71-77. In:
    • Ueland, Per Magne; Rozen, Rima. 2004. MTHFR Polymorphisms and Disease. 206 pages. ISBN: 1-58706-217-8.

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