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Stephanie Le Hellard

Professor, Human Genetics

The aim of my research group is to identify how different layers of genetics, epigenetics and gene expression can be involved together in the development of mental disorders, their outcome and how they are modulated by the environment.

I am a core researcher at the NORMENT, a Norwegian Centre of Excellence for Research on Mental Health. The NORMENT is described here: http://www.med.uio.no/norment/english/ In Bergen I am situated at the Dr Martens group for research on biological psychiatry, our research activity is described here: http://www.uib.no/en/rg/geneticsgroup/106397/martens-group#at-a-glance

Description of our group in the NORMENT centre:

Epigenetics and multi-omics

About the group

The group consists of people with background in genetics, statistics, medicine and informatics who together bring their complementary expertise to try understand the interaction between genetic and environmental risk in mental disorders. We work in close collaboration with clinicians.

We use datasets generated in house or publicly available that combine genetic, epigenetic and gene expression datasets for mental disorders (mostly schizophrenia and bipolar disorders) that are in addition well annotated for environmental factors.

Aims

Genetic studies of psychiatric disorders have identified numerous genomic regions that harbor genetic variants which explain some of the risk to develop illness. In addition to the genetic risk, many environmental risks (drug use, trauma, migration, etc) can affect the development and the outcome of mental disorders.

Our aim is to identify how the different layers of genetics, epigenetics and gene expression can be involved together in the development of mental disorders, their outcome and how they are modulated by the environment.

Projects
  • Molecular mechanisms of exposure to cannabis in patients with schizophrenia: We are looking at the difference between cannabis users and non users in DNA methylation and modelling these differences in cell models.
  • The 3D sample: In a set of patients and controls we have genetic information, epigenetic information and gene expression. We are combining these 3 datasets to try identify common effects across the 3 dimensions.
  • DNA methylation in psychiatric disorders, and mediation of gene by environment effects, from birth to adulthood. We are examining the variations on DNA methylation associated with mental disorders.
  • An evolutionary epigenetics approach to schizophrenia: We examine if regions differentially methylated in the recent human evolution can be implicated in schizophrenia.
Selected publications
  • van der Meer D, et al. (2018) Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Mol Psychiatry.
  • Banerjee N, et al. (2018) Recently evolved human-specific methylated regions are enriched in schizophrenia signals. Bmc Evol Biol 18.
  • Hughes T, et al. (2018) Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder. Transl Psychiatry 8(1):210.
  • Banerjee N, et al. (2018) Analysis of differentially methylated regions in great apes and extinct hominids provides support for the evolutionary hypothesis of schizophrenia. Schizophr Res.
  • Davies G, et al. (2018) Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications 9.

I teach Genetics and Evolution to medical students in their 3rd semester, at the Faculty of Medicine, UiB.

I teach a MSc course in Human Genetics (HUMGEN301) at the Faculty of Medicine, UiB. http://www.uib.no/en/course/HUMGEN301

I also participate in the IGSIN course for PhD students, UiB, and the Master course in Genetics of Cognitive Neuroscience at the University of Oslo.

 

Academic article
  • Lam, Max; Hill, W. David; Trampush, Joey W.; Yu, Jin; Knowles, Emma; Davies, Gail; Stahl, Eli; Huckins, Laura; Liewald, David C.; Djurovic, Srdjan; Melle, Ingrid; Sundet, Kjetil Søren; Christoforou, Andrea; Reinvang, Ivar; DeRosse, Pamela; Lundervold, Astri; Steen, Vidar Martin; Espeseth, Thomas; Räikkönen, Katri; Widén, Elisabeth; Palotie, Aarno; Eriksson, Johan G.; Giegling, Ina; Konte, Bettina; Hartmann, Annette M.; Roussos, Panos; Giakoumaki, Stella; Burdick, Katherine E.; Payton, Antony; Ollier, William; Chiba-Falek, Ornit; Attix, Deborah K.; Need, Anna C.; Cirulli, Elizabeth T.; Voineskos, Aristotle N.; Stefanis, Nikos C.; Avramopoulos, Dimitrios; Hatzimanolis, Alex; Arking, Dan E.; Smyrnis, Nikolaos; Bilder, Robert M.; Freimer, Nelson A.; Cannon, Tyrone D.; London, Edythe; Poldrack, Russell A.; Sabb, Fred W.; Congdon, Eliza; Conley, Emily Drabant; Scult, Matthew A.; Dickinson, Dwight; Straub, Richard E.; Donohoe, Gary; Morris, Derek; Corvin, Aiden; Gill, Michael; Hariri, Ahmad R.; Weinberger, Daniel R.; Pendleton, Neil; Bitsios, Panos; Rujescu, Dan; Lahti, Jari; Le Hellard, Stephanie; Keller, Matthew C.; Andreassen, Ole Andreas; Deary, Ian J.; Glahn, David C.; Malhotra, Anil K.; Lencz, Todd. 2019. Pleiotropic meta-analysis of cognition, education, and schizophrenia differentiates roles of early neurodevelopmental and adult synaptic pathways. American Journal of Human Genetics. 334-350.
  • Lee, Phil H.; Antilla, Verneri; Won, Hyejung; Feng, Yen-Chen A.; Rosenthal, Jacob; Zhu, Zhaozhong; Bettella, Francesco; Agartz, Ingrid; Dale, Anders; Nærland, Terje; Elvsåshagen, Torbjørn; Ødegaard, Ketil Joachim; Melle, Ingrid; Bøen, Erlend; Knudsen, Gun Peggy Strømstad; Le Hellard, Stephanie; Reichborn-Kjennerud, Ted; Smeland, Olav Bjerkehagen; Kendler, Kenneth S.; Andreassen, Ole Andreas; Neale, Benjamin M; Smoller, Jordan W.; Tucker-Drob, Elliot M.; Nivard, Michel G.; Grotzinger, Andrew D.; Posthuma, Danielle; Wang, Meg M.-J.; Yu, Dongmei; Stahl, Eli A.; Walters, Raymond K.; Anney, Richard J.L.; Duncan, Laramie E.; Ge, Tian; Adolfsson, Rolf; Banaschewski, Tobias J; Belangero, Sintia I.; Cook, Edwin H.; Coppola, Giovanni; Derks, Eske M.; Hoekstra, Pieter J.; Kaprio, Jaakko; Keski-Rahkonen, Anna; Kirov, George; Kranzler, Henry R.; Luykx, Jurjen J.; Rohde, Luis A.; Zai, Clement; Agerbo, Esben; Arranz, M.J.; Asherson, Philip. 2019. Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders. Cell. 1469-1482.
  • Lee, Phil H.; Antilla, Verneri; Won, Hyejung; Feng, Yen-Chen A.; Rosenthal, Jacob; Zhu, Zhaozhong; Tucker-Drob, Elliot M.; Nivard, Michel G.; Grotzinger, Andrew D.; Posthuma, Danielle; Yu, Dongmei; Stahl, Eli A.; Walters, Raymond K.; Anney, Richard J.L.; Duncan, Laramie E.; Ge, Tian; Belangero, Sintia I.; Cook, Edwin H.; Hoekstra, Pieter J.; Keski-Rahkonen, Anna; Kirov, George; Luykx, Jurjen J.; Rohde, Luis A.; Agerbo, Esben; Arranz, M.J.; Asherson, Philip; Bækvad-Hansen, Marie; Bellgrove, Mark A.; Belliveau Jr, Richard A.; Buitelaar, Jan; Bybjerg-Grauholm, Jonas; Casas, Miquel; Chambert, Kimberly; Cerrato, Felecia; Churchhouse, Claire; Cormand, Bru; Crosbie, Jennifer; Dalsgaard, Søren; Haavik, Jan; Hakonarson, Hakon; Hansen, Christine S.; Mors, Ole; Zayats, Tetyana; Bettella, Francesco; Hope, Sigrun; Hultman, Christina M.; Nærland, Terje; Bøen, Erlend; Elvsåshagen, Torbjørn; Ødegaard, Ketil Joachim; Malt, Ulrik Fredrik; Melle, Ingrid; Reinbold, Céline Sonja; Smeland, Olav Bjerkehagen; Wang, Yunpeng; Espeseth, Thomas; Knudsen, Gun Peggy Strømstad; Le Hellard, Stephanie; Reichborn-Kjennerud, Ted; Jönsson, Erik Gunnar; Andreassen, Ole Andreas; Agartz, Ingrid; Morken, Gunnar; Stordal, Eystein; Vaaler, Arne; Joa, Inge. 2019. Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders. Cell. 1469-1482.
  • Watson, Hunna J.; Yilmaz, Zeynep; Thornton, Laura M.; Hübel, Christopher; Coleman, Jonathan R. I.; Gaspar, Héléna A.; Bryois, Julien; Hinney, Anke; Leppä, Virpi M.; Mattheisen, Manuel; Medland, Sarah E.; Ripke, Stephan; Yao, Shuyang; Giusti-Rodríguez, Paola; Hanscombe, Ken B.; Purves, Kirstin L.; Adan, Roger A.H.; Alfredsson, Lars; Ando, Tetsuya; Andreassen, Ole Andreas; Baker, Jessica H; Berrettini, Wade H.; Boehm, Ilka; Boni, Claudette; Perica, Vesna Boraska; Buehren, Katharina; Burghardt, Roland; Cassina, Matteo; Cichon, Sven; Clementi, Maurizio; Cone, Roger D.; Courtet, Philippe; Crow, Scott; Crowley, James J.; Danner, Unna N.; Davis, Oliver S.P.; de Zwaan, Martina; Dedoussis, George; Degortes, Daniela; DeSocio, Janiece E.; Dick, Danielle M.; Dikeos, Dimitris; Dina, Christian; Dmitrzak-Weglarz, Monika; Docampo, Elisa; Duncan, Laramie E.; Egberts, Karin; Ehrlich, Stefan; Escaramis, Geòrgia; Esko, Tõnu; Estivill, Xavier; Farmer, Anne; Favaro, Angela; Fernández-Aranda, Fernando; Fichter, Manfred M.; Fischer, Krista; Föcker, Manuel; Foretova, Lenka; Forstner, Andreas J.; Forzan, Monica; Franklin, Christopher S.; Gallinger, Steven; Giegling, Ina; Giuranna, Johanna; Gonidakis, Fragiskos; Gorwood, Philip; Mayora, Monica Gratacos; Guillaume, Sebastien; Guo, Yiran; Hakonarson, Hakon; Hatzikotoulas, Konstantinos; Hauser, Joanna; Hebebrand, Johannes; Helder, Sietske G.; Herms, Stefan; Herpertz-Dahlmann, Beate; Herzog, Wolfgang; Huckins, Laura M.; Hudson, James I.; Imgart, Hartmut; Inoko, Hidetoshi; Janout, Vladimir; Jiménez-Murcia, Susana; Julià, Antonio; Kalsi, Gursharan; Kaminská, Deborah; Kaprio, Jaakko; Karhunen, Leila; Karwautz, Andreas; Kas, Martien J.H.; Kennedy, James L.; Keski-Rahkonen, Anna; Kiezebrink, Kirsty; Kim, Youl-Ri; Klareskog, Lars; Klump, Kelly L.; Knudsen, Gun Peggy S.; La Via, Maria C.; Le Hellard, Stephanie; Levitan, Robert D. 2019. Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nature Genetics. 1207-1214.
  • Satizabal, Claudia L.; Adams, Hieab H.H.; Hibar, Derrek; White, Charles C.; Knol, Maria J.; Stein, Jason L.; Scholz, Markus; Sargurupremraj, Muralidharan; Jahanshad, Neda; Roshchupkin, Gennady V.; Smith, Albert V.; Bis, Joshua C.; Jian, Xueqiu; Luciano, Michelle; Hofer, Edith; Teumer, Alexander; van der Lee, Sven J.; Yang, Jingyun; Yanek, Lisa R.; Lee, Tom V.; Li, Shuo; Hu, Yanhui; Koh, Jia Yu; Eicher, John D.; Desrivières, Sylvane; Arias-Vasquez, Alejandro; Chauhan, Ganesh; Athanasiu, Lavinia; Rentería, Miguel E.; Kim, Sungeun; Hoehn, David; Armstrong, Nicola J.; Chen, Qiang; Holmes, Avram J.; den Braber, Anouk; Kloszewska, Iwona; Andersson, Micael; Espeseth, Thomas; Grimm, Oliver; Abramovic, Lucija; Alhusaini, Saud; Milaneschi, Yuri; Papmeyer, Martina; Axelsson, Tomas; Ehrlich, Stefan; Roiz-Santiáñez, Roberto; Kraemer, Bernd; Håberg, Asta; Jones, Hannah J; Pike, G. Bruce; Stein, Dan J.; Stevens, Allison; Bralten, Janita; Vernooij, Meike W.; Harris, Tamara B.; Filippi, Irina; Witte, A Veronica; Guadalupe, Tulio; Wittfeld, Katharina; Mosley, Thomas H.; Becker, James T.; Hagenaars, Saskia P.; Saba, Yasaman; Cuellar-Partida, Gabriel; Amin, Najaf; Hilal, Saima; Nho, Kwangsik; Mirza-Schreiber, Nazanin; Arfanakis, Konstantinos; Becker, Diane M.; Ames, David; Goldman, Aaron L.; Lee, Phil H.; Boomsma, Dorret I.; Lovestone, Simon; Giddaluru, Sudheer; Le Hellard, Stephanie; Mattheisen, Manuel; Bohlken, Marc M.; Kasperaviciute, Dalia; Schmaal, Lianne; Lawrie, Stephen M.; Agartz, Ingrid; Walton, Esther; Tordesillas-Gutierrez, Diana; Davies, Gareth E.; Shin, Jean; Ipser, Jonathan C.; Vinke, Louis N.; Hoogman, Martine; Jia, Tianye; Burkhardt, Ralph; Klein, Marieke; Crivello, Fabrice; Janowitz, Deborah; Carmichael, Owen; Haukvik, Unn Kristin H.; Aribisala, Benjamin S.; Schmidt, Helena; Strike, Lachlan T. 2019. Genetic architecture of subcortical brain structures in 38,851 individuals. Nature Genetics. 1624-1636.
  • Kaufmann, Tobias; van der Meer, Dennis; Doan, Nhat Trung; Schwarz, Emanuel; Lund, Martina Jonette; Agartz, Ingrid; Alnæs, Dag; Barch, Deanna M.; Baur-Streubel, Ramona; Bertolino, Alessandro; Bettella, Francesco; Beyer, Mona K.; Bøen, Erlend; Borgwardt, Stefan; Brandt, Christine Lycke; Buitelaar, Jan; Celius, Elisabeth Gulowsen; Cervenka, Simon; Conzelmann, Annette; Còrdova Palomera, Aldo; Dale, Anders; de Quervain, Dominique J.F.; di Carlo, Pasquale; Djurovic, Srdjan; Dørum, Erlend Solberg; Eisenacher, Sarah; Elvsåshagen, Torbjørn; Espeseth, Thomas; Fatouros-Bergman, Helena; Flyckt, Lena; Franke, Barbara; Frei, Oleksandr; Haatveit, Beathe ; Håberg, Asta; Harbo, Hanne Flinstad; Hartman, Catharina A; Heslenfeld, Dirk J; Hoekstra, Pieter J; Høgestøl, Einar August; Jernigan, Terry L.; Jonassen, Rune; Jönsson, Erik Gunnar; Kirsch, Peter; Kłoszewska, Iwona; Kolskår, Knut-Kristian; Landrø, Nils Inge; Le Hellard, Stephanie; Lesch, Klaus-Peter; Lovestone, Simon; Lundervold, Arvid; Lundervold, Astri; Maglanoc, Luigi Angelo; Malt, Ulrik Fredrik; Mecocci, Patrizia; Melle, Ingrid; Meyer-Lindenberg, Andreas; Moberget, Torgeir; Norbom, Linn Christin Bonaventure; Nordvik, Jan Egil; Nyberg, Lars; Oosterlaan, Jaap; Papalino, Marco; Papassotiropoulos, Andreas; Pauli, Paul; Pergola, Giulio; Persson, Karin Ester Torun; Richard, Geneviève; Rokicki, Jaroslav; Sanders, Anne-Marthe; Selbæk, Geir; Shadrin, Alexey A.; Smeland, Olav Bjerkehagen; Soininen, Hilkka; Sowa, Piotr; Steen, Vidar Martin; Tsolaki, Magda; Ulrichsen, Kristine Moe; Vellas, Bruno; Wang, Lei; Westman, Eric; Ziegler, Georg C.; Zink, Mathias; Andreassen, Ole Andreas; Westlye, Lars Tjelta. 2019. Common brain disorders are associated with heritable patterns of apparent aging of the brain. Nature Neuroscience. 1617-1623.
  • van der Meer, Dennis; Sønderby, Ida Elken; Kaufmann, Tobias; Walters, G. Bragi; Abdellaoui, Abdel; Ames, David; Amunts, Katrin; Andersson, Micael; Armstrong, Nicola J.; Bernard, Manon; Blackburn, Nicholas B.; Blangero, John; Boomsma, Dorret I.; Brodaty, Henry; Brouwer, Rachel M.; Bülow, Robin; Cahn, Wiepke; Calhoun, Vince D.; Caspers, Svenja; Cavalleri, Gianpiero L.; Ching, Christopher R.K.; Cichon, Sven; Ciufolini, Simone; Corvin, Aiden; Crespo-Facorro, Benedicto; Curran, Joanne E.; Dalvie, Shareefa; Dazzan, Paola; de Geus, Eco J.C.; de Zubicaray, Greig I.; de Zwarte, Sonja M.C.; Delanty, Norman; den Braber, Anouk; Desrivieres, Sylvane; di Forti, Marta; Doherty, Joanne L.; Donohoe, Gary; Ehrlich, Stefan; Eising, Else; Espeseth, Thomas; Fisher, Simon E.; Fladby, Tormod; Frei, Oleksandr; Frouin, Vincent; Fukunaga, Masaki; Gareau, Thomas; Glahn, David C.; Grabe, Hans J.; Groenewold, Nynke A.; Gustafsson, Omar; Haavik, Jan; Håberg, Asta; Hashimoto, Ryota; Hehir-Kwa, Jayne Y.; Hibar, Derrek; Hillegers, Manon H.J.; Hoffmann, Per; Holleran, Laurena; Hottenga, Jouke-Jan; Hulshoff Pol, Hilleke E.; Ikeda, Masashi; Jacquemont, Sébastien; Jahanshad, Neda; Jockwitz, Christiane; Johansson, Stefan; Jönsson, Erik Gunnar; Kikuchi, Masataka; Knowles, Emma E.M.; Kwok, John B.; Le Hellard, Stephanie; Linden, David E.J.; Liu, Jingyu; Lundervold, Arvid; Lundervold, Astri; Martin, Nicholas G.; Mather, Karen A.; Mathias, Samuel R.; McMahon, Katie L.; McRae, Allan F.; Medland, Sarah E.; Moberget, Torgeir; Moreau, Clara; Morris, Derek W.; Mühleisen, Thomas W.; Murray, Robin M.; Nordvik, Jan Egil; Nyberg, Lars; Olde Loohuis, Loes M.; Ophoff, Roel A.; Owen, Michael J.; Paus, Tomáš; Pausova, Zdenka; Peralta, Juan M.; Pike, Bruce; Prieto, Carlos; Quinlan, Erin Burke; Reinbold, Céline Sonja; Reis Marques, Tiago; Rucker, James J.H.; Sachdev, Perminder S. 2019. Association of copy number variation of the 15q11.2 BP1-BP2 region with cortical and subcortical morphology and cognition. JAMA psychiatry. 11 pages.
  • Fan, Chun Chieh; Schork, Andrew J.; Brown, Timothy T.; Spencer, Barbara E.; Akshoomoff, Natacha; Chen, Chi-Hua; Kuperman, Joshua M.; Hagler, Donald J.; Steen, Vidar Martin; Le Hellard, Stephanie; Håberg, Asta; Espeseth, Thomas; Andreassen, Ole Andreas; Dale, Anders; Jernigan, Terry L.; Halgren, Eric. 2018. Williams Syndrome neuroanatomical score associates with GTF2IRD1 in large-scale magnetic resonance imaging cohorts: A proof of concept for multivariate endophenotypes. Translational psychiatry. 1-8.
  • Davies, Gail; Lam, Max; Harris, Sarah E.; Trampush, Joey W.; Luciano, Michelle; Hill, W. David; Hagenaars, Saskia P.; Ritchie, Stuart J.; Marioni, Riccardo E.; Fawns-Ritchie, Chloe; Liewald, David C.M.; Okely, Judith A.; Ahola-Olli, Ari V.; Barnes, Catriona L.K.; Bertram, Lars; Bis, Joshua C.; Burdick, Katherine E.; Derosse, Pamela; Djurovic, Srdjan; Espeseth, Thomas; Giakoumaki, Stella; Giddaluru, Sudheer; Gustavson, Daniel E.; Hayward, Caroline; Hofer, Edith; Ikram, M. Arfan; Karlsson, Robert; Knowles, Emma; Lahti, Jari; Leber, Markus; Li, Shuo; Mather, Karen A.; Melle, Ingrid; Morris, Derek; Oldmeadow, Christopher; Palviainen, Teemu; Payton, Antony; Pazoki, Raha; Petrovic, Katja; Reynolds, Chandra A.; Sargurupremraj, Muralidharan; Scholz, Markus; Smith, Jennifer A.; Smith, Albert V.; Terzikhan, Natalie; Thalamuthu, Anbupalam; Trompet, Stella; van der Lee, Sven J.; Ware, Erin B.; Windham, B. Gwen; Wright, Margaret J.; Yang, Jingyun; Yu, Jin; Ames, David; Amin, Najaf; Amouyel, Philippe; Andreassen, Ole Andreas; Armstrong, Nicola J.; Assareh, Amelia A; Attia, John R.; Attix, Deborah; Avramopoulos, Dimitrios; Bennett, David A.; Böhmer, Anne C.; Boyle, Patricia A.; Brodaty, Henry; Campbell, Harry; Cannon, Tyrone D.; Cirulli, Elizabeth T.; Congdon, Eliza; Conley, Emily Drabant; Corley, Janie; Cox, Simon R.; Dale, Anders; Dehghan, Abbas; Dick, Danielle; Dickinson, Dwight; Eriksson, Johan G.; Evangelou, Evangelos; Faul, Jessica D.; Ford, Ian; Freimer, Nelson A.; Gao, He; Giegling, Ina; Gillespie, Nathan A.; Gordon, Scott D.; Gottesman, Rebecca F.; Griswold, Michael E.; Gudnason, Vilmundur; Harris, Tamara B.; Hartmann, Annette M.; Hatzimanolis, Alex; Heiss, Gerardo; Holliday, Elizabeth G.; Joshi, Peter K.; Kähönen, Mika; Kardia, Sharon L.R.; Karlsson, Ida; Kleineidam, Luca; Knopman, David S. 2018. Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications. 1-16.
  • Banerjee, Niladri; Polushina, Tatiana; Bettella, Francesco; Giddaluru, Sudheer; Steen, Vidar Martin; Andreassen, Ole Andreas; Le Hellard, Stephanie. 2018. Recently evolved human-specific methylated regions are enriched in schizophrenia signals. BMC Evolutionary Biology. 1-11.
  • Witoelar, Aree; Rongve, Arvid; Almdahl, Ina Selseth; Ulstein, Ingun; Engvig, Andreas; White, Linda Rosemary; Selbæk, Geir; Stordal, Eystein; Andersen, Fred; Brækhus, Anne; Saltvedt, Ingvild; Engedal, Knut; Hughes, Timothy; Bergh, Sverre; Bråthen, Geir; Bogdanovic, Nenad; Bettella, Francesco; Wang, Yunpeng; Athanasiu, Lavinia; Bahrami, Shahram; Le Hellard, Stephanie; Giddaluru, Sudheer; Dale, Anders M; Sando, Sigrid Botne; Steinberg, Stacy; Stefansson, Hreinn; Snaedal, Jon; Desikan, Rahul S; Stefansson, Kari; Aarsland, Dag; Djurovic, Srdjan; Fladby, Tormod; Andreassen, Ole Andreas. 2018. Meta-analysis of Alzheimer’s disease on 9,751 samples from Norway and IGAP study identifies four risk loci. Scientific Reports. 8 pages.
  • Savage, Jeanne E.; Jansen, Philip R.; Stringer, Sven; Watanabe, Kyoko; Bryois, Julien; de Leeuw, Christiaan A.; Nagel, Mats; Awasthi, Swapnil; Barr, Peter B.; Coleman, Jonathan R.I.; Grasby, Katrina L.; Hammerschlag, Anke R.; Kaminski, Jakob A.; Karlsson, Robert; Krapohl, Eva; Lam, Max; Nygaard, Marianne; Reynolds, Chandra A.; Trampush, Joey W.; Young, Hannah; Zabaneh, Delilah; Hägg, Sara; Hansell, Narelle K.; Karlsson, Ida K.; Linnarsson, Sten; Montgomery, Grant W.; Muñoz-Manchado, Ana B.; Quinlan, Erin B.; Schumann, Gunter; Skene, Nathan G.; Webb, Bradley T.; White, Tonya; Arking, Dan E.; Avramopoulos, Dimitrios; Bilder, Robert M.; Bitsios, Panos; Burdick, Katherine E.; Cannon, Tyrone D.; Chiba-Falek, Ornit; Christoforou, Andrea; Cirulli, Elizabeth T.; Congdon, Eliza; Corvin, Aiden; Davies, Gail; Deary, Ian J.; DeRosse, Pamela; Dickinson, Dwight; Djurovic, Srdjan; Donohoe, Gary; Conley, Emily Drabant; Eriksson, Johan G.; Espeseth, Thomas; Freimer, Nelson A.; Giakoumaki, Stella; Giegling, Ina; Gill, Michael; Glahn, David C.; Hariri, Ahmad; Hatzimanolis, Alex; Keller, Matthew C.; Knowles, Emma; Koltai, Deborah; Konte, Bettina; Lahti, Jari; Le Hellard, Stephanie; Lencz, Todd; Liewald, David C.; London, Edythe; Lundervold, Astri; Malhotra, Anil K.; Melle, Ingrid; Morris, Derek; Need, Anna C.; Ollier, William; Palotie, Aarno; Payton, Antony; Pendleton, Neil; Poldrack, Russell A.; Räikkönen, Katri; Reinvang, Ivar; Roussos, Panos; Rujescu, Dan; Sabb, Fred W.; Scult, Matthew A; Smeland, Olav Bjerkehagen; Smyrnis, Nikolaos; Starr, John M; Steen, Vidar Martin; Stefanis, Nikos C.; Straub, Richard E.; Sundet, Kjetil Søren; Tiemeier, Henning; Voineskos, Aristotle N.; Weinberger, Daniel R.; Widén, Elisabeth; Yu, Jin; Abecasis, Goncalo; Andreassen, Ole Andreas; Breen, Gerome; Christiansen, Lene. 2018. Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Nature Genetics. 912-919.
  • Stokowy, Tomasz; Polushina, Tatiana; Sønderby, Ida Elken; Karlsson, Robert; Giddaluru, Sudheer; Le Hellard, Stephanie; Bergen, Sarah E.; Sullivan, Patrick F.; Andreassen, Ole Andreas; Djurovic, Srdjan; Hultman, Christina M.; Steen, Vidar Martin. 2018. Genetic variation in 117 myelination-related genes in schizophrenia: Replication of association to lipid biosynthesis genes. Scientific Reports. 1-8.
  • Tronstad, Rune Rose; Polushina, Tatiana; Brattbakk, Hans-Richard; Stansberg, Christine; Volkmann, Hilde Løland Von; Hanevik, Kurt; Ellinghaus, Eva; Jørgensen, Silje Fjellgård; Ersland, Kari Merete; Pham, Khanh Do-Cong; Gilja, Odd Helge; Hovdenak, Nils; Hausken, Trygve; Vatn, Morten H; Franke, Andre; Knappskog, Per; Le Hellard, Stephanie; Karlsen, Tom Hemming; Fiskerstrand, Torunn. 2018. Genetic and transcriptional analysis of inflammatory bowel disease-associated pathways in patients with GUCY2C-linked familial diarrhea. Scandinavian Journal of Gastroenterology. 1264-1273.
  • Hughes, Timothy; Sønderby, Ida Elken; Polushina, Tatiana; Hansson, Lars Johan Axel; Holmgren, Asbjørn; Athanasiu, Lavinia; Melbø-Jørgensen, Christian; Hassani, Sahar; Hoeffding, Louise K.; Herms, Stefan; Bergen, Sarah E.; Karlsson, Robert; Song, Jie; Rietschel, Marcella; Nöthen, Markus M.; Forstner, Andreas J.; Hoffmann, Per; Hultman, Christina M.; Landén, Mikael; Cichon, Sven; Werge, Thomas; Andreassen, Ole Andreas; Le Hellard, Stephanie; Djurovic, Srdjan. 2018. Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder. Translational psychiatry. 1-10.
  • van der Meer, Dennis; Rokicki, Jaroslav; Kaufmann, Tobias; Còrdova Palomera, Aldo; Moberget, Torgeir; Alnæs, Dag; Bettella, Francesco; Frei, Oleksandr; Doan, Nhat Trung; Sønderby, Ida Elken; Smeland, Olav Bjerkehagen; Agartz, Ingrid; Bertolino, Alessandro; Bralten, Janita; Brandt, Christine Lycke; Buitelaar, Jan K.; Djurovic, Srdjan; van Donkelaar, Marjolein; Dørum, Erlend Solberg; Espeseth, Thomas; Faraone, Stephen V.; Fernandéz, Guillén; Fisher, Simon E.; Franke, Barbara; Haatveit, Beathe Christin; Hartman, Catharina A.; Hoekstra, Pieter J.; Håberg, Asta; Jönsson, Erik Gunnar; Kolskår, Knut-Kristian; Le Hellard, Stephanie; Lund, Martina Jonette; Lundervold, Astri; Lundervold, Arvid; Melle, Ingrid; Monereo Sanchez, Jennifer; Norbom, Linn Christin Bonaventure; Nordvik, Jan Egil; Nyberg, Lars; Oosterlaan, Jaap; Papalino, Marco; Papassotiropoulos, Andreas; Pergola, Giulio; de Quervain, Dominique J.F.; Richard, Geneviéve´; Sanders, Anne-Marthe; Selvaggi, Pierluigi; Shumskaya, Elena; Steen, Vidar Martin; Tønnesen, Siren; Ulrichsen, Kristine Moe; Zwiers, Marcel P.; Andreassen, Ole Andreas; Westlye, Lars Tjelta. 2018. Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Molecular Psychiatry. 1-13.
  • Banerjee, Niladri; Polushina, Tatiana; Bettella, Francesco; Steen, Vidar Martin; Andreassen, Ole Andreas; Le Hellard, Stephanie. 2018. Analysis of differentially methylated regions in great apes and extinct hominids provides support for the evolutionary hypothesis of schizophrenia. Schizophrenia Research. 8 pages.
  • Maretty, Lasse; Jensen, Jacob Malte; Petersen, Bent; Sibbesen, Jonas Andreas; Liu, Siyang; Villesen, Palle; Skov, Laurits; Belling, Kirstine; Theil Have, Christian; Izarzugaza, José M.G.; Grosjean, Marie; Bork-Jensen, Jette; Grove, Jakob; Als, Thomas D.; Huang, Shujia; Chang, Yuqi; Xu, Ruiqi; Ye, Weijian; Rao, Junhua; Guo, Xiaosen; Sun, Jihua; Cao, Hongzhi; Ye, Chen; Van Beusekom, Johan; Espeseth, Thomas; Flindt, Esben; Friborg, Rune Møllegaard; Halager, Anders E.; Le Hellard, Stephanie; Hultman, Christina M.; Lescai, Francesco; Li, Shengting; Lund, Ole; Løngren, Peter; Mailund, Thomas; Matey-Hernandez, Maria Luisa; Mors, Ole; Pedersen, Christian N.S.; Sicheritz-Pontén, Thomas; Sullivan, Patrick; Syed, Ali; Westergaard, David; Yadav, Rachita; Li, Ning; Xu, Xun; Hansen, Torben; Krogh, Anders; Bolund, Lars; Sørensen, Thorkild I.A.; Pedersen, Oluf; Gupta, Ramneek; Rasmussen, Simon; Besenbacher, Søren; Børglum, Anders D.; Wang, Jun; Eiberg, Hans; Kristiansen, Karsten; Brunak, Søren; Schierup, Mikkel Heide. 2017. Sequencing and de novo assembly of 150 genomes from Denmark as a population reference. Nature. 87-91.
  • Aas, Monica; Melle, Ingrid; Bettella, Francesco; Djurovic, Srdjan; Le Hellard, Stephanie; Bjella, Thomas; Ringen, Petter Andreas; Lagerberg, Trine Vik; Smeland, Olav Bjerkehagen; Agartz, Ingrid; Andreassen, Ole Andreas; Tesli, Martin Steen. 2017. Psychotic patients who used cannabis frequently before illness onset have higher genetic predisposition to schizophrenia than those who did not. Psychological Medicine. 43-49.
  • Hibar, Derrek; Adams, Hieab H.H.; Jahanshad, Neda; Chauhan, Ganesh; Stein, Jason L.; Hofer, Edith; Renteriá, Miguel E.; Bis, Joshua C.; Arias-Vasquez, Alejandro; Ikram, M. Kamran; Desrivières, Sylvane; Vernooij, Meike W; Abramovic, Lucija; Alhusaini, Saud; Amin, Najaf; Andersson, Micael; Arfanakis, Konstantinos; Aribisala, Benjamin S.; Armstrong, Nicola J.; Athanasiu, Lavinia; Axelsson, Tomas; Beecham, Ashley H.; Beiser, Alexa; Bernard, Manon; Blanton, Susan H.; Bohlken, Marc M.; Boks, Marco P.; Bralten, Janita; Brickman, Adam M.; Carmichael, Owen; Chakravarty, M. Mallar; Chen, Qiang; Ching, Christopher R.K.; Chouraki, Vincent; Cuellar-Partida, Gabriel; Crivello, Fabrice; Den Braber, Anouk; Doan, Nhat Trung; Ehrlich, Stefan; Giddaluru, Sudheer; Goldman, Aaron L; Gottesman, Rebecca F.; Grimm, Oliver; Griswold, Michael E.; Guadalupe, Tulio; Gutman, Boris A.; Hass, Johanna; Haukvik, Unn Kristin H.; Hoehn, David; Holmes, Avram J.; Hoogman, Martine; Janowitz, Deborah; Jia, Tianye; Jørgensen, Kjetil Nordbø; Karbalai, Nazanin; Kasperaviciute, Dalia; Kim, Sungeun; Klein, Marieke; Kraemer, Bernd; Lee, Phil H.; Liewald, David C.M.; Lopez, Lorna M.; Luciano, Michelle; MacAre, Christine; Marquand, André F.; Matarin, Mar; Mather, Karen A.; Mattheisen, Manuel; McKay, David R.; Milaneschi, Yuri; Muñoz Maniega, Susana; Nho, Kwangsik; Nugent, Allison C.; Nyquist, Paul; Loohuis, Loes M. Olde; Oosterlaan, Jaap; Papmeyer, Martina; Pirpamer, Lukas; Pütz, Benno; Ramasamy, Adaikalavan; Richards, Jennifer S.; Risacher, Shannon L.; Roiz-Santiañez, Roberto; Rommelse, Nanda; Ropele, Stefan; Rose, Emma J.; Royle, Natalie A.; Rundek, Tatjana; Sämann, Philipp G.; Saremi, Arvin; Satizabal, Claudia L.; Schmaal, Lianne; Schork, Andrew J.; Shen, Li; Shin, Jean; Shumskaya, Elena; Smith, Albert V.; Sprooten, Emma; Strike, Lachlan T.; Teumer, Alexander. 2017. Novel genetic loci associated with hippocampal volume. Nature Communications. 1-12.
  • Lam, Max; Trampush, Joey W.; Yu, Jin; Knowles, Emma; Davies, Gail; Liewald, David C.; Starr, John M.; Djurovic, Srdjan; Melle, Ingrid; Sundet, Kjetil Søren; Christoforou, Andrea; Reinvang, Ivar; DeRosse, Pamela; Lundervold, Astri; Steen, Vidar Martin; Espeseth, Thomas; Räikkönen, Katri; Widén, Elisabeth; Palotie, Aarno; Eriksson, Johan G.; Giegling, Ina; Konte, Bettina; Roussos, Panos; Giakoumaki, Stella; Burdick, Katherine E.; Payton, Antony; Ollier, William; Chiba-Falek, Ornit; Attix, Deborah K.; Need, Anna C.; Cirulli, Elizabeth Trilby; Voineskos, Aristotle N.; Stefanis, Nikos C.; Avramopoulos, Dimitrios A.; Hatzimanolis, Alex; Arking, Dan E.; Smyrnis, Nikolaos; Bilder, Robert M.; Freimer, Nelson A.; Cannon, Tyrone D.; London, Edythe D; Poldrack, Russell A.; Sabb, Fred W.; Congdon, Eliza L.; Conley, Emily Drabant; Scult, Matthew A.; Dickinson, Dwight; Straub, Richard E.; Donohoe, Gary; Morris, Derek; Corvin, Aiden; Gill, Michael; Hariri, Ahmad R.; Weinberger, Daniel R.; Pendleton, Neil; Bitsios, Panos; Rujescu, Dan; Lahti, Jari; Le Hellard, Stephanie; Keller, Matthew C.; Andreassen, Ole Andreas; Deary, Ian J.; Glahn, David C.; Malhotra, Anil K.; Lencz, Todd. 2017. Large-scale cognitive GWAS meta-analysis reveals tissue-specific neural expression and potential nootropic drug targets. Cell reports. 2597-2613.
  • Le Hellard, Stephanie; Wang, Yunpeng; Witoelar, Aree; Zuber, Verena; Bettella, Francesco; Hugdahl, Kenneth; Espeseth, Thomas; Steen, Vidar Martin; Melle, Ingrid; Desikan, Rahul S.; Schork, Andrew J.; Thompson, Wesley Kurt; Dale, Anders; Djurovic, Srdjan; Andreassen, Ole Andreas. 2017. Identification of gene loci that overlap between schizophrenia and educational attainment. Schizophrenia Bulletin. 654-664.
  • Trampush, Joey W.; Yang, M.L.Z.; Yu, Jin; Knowles, Emma; Davies, Gail; Liewald, David C.M.; Starr, John M.; Djurovic, Srdjan; Melle, Ingrid; Sundet, Kjetil Søren; Christoforou, Andrea; Reinvang, Ivar; DeRosse, Pamela; Lundervold, Astri; Steen, Vidar Martin; Espeseth, Thomas; Räikkönen, Katri; Widén, Elisabeth; Palotie, Aarno; Eriksson, Johan Gunnar; Giegling, Ina; Konte, Bettina; Roussos, Panos; Giakoumaki, Stella; Burdick, Katherine E.; Payton, Antony; Ollier, William E.R.; Horan, Michael Arthur; Chiba-Falek, Ornit; Attix, Deborah K.; Need, Anna C.; Cirulli, Elizabeth Trilby; Voineskos, Aristotle N.; Stefanis, Nikos C.; Avramopoulos, Dimitrios A.; Hatzimanolis, Alex; Arking, Dan E.; Smyrnis, Nikolaos; Bilder, Robert Martin; Freimer, Nelson A.; Cannon, Tyrone D.; London, Edyth; Poldrack, Russell Alan; Sabb, Fred W.; Congdon, Eliza L.; Conley, Emily Drabant; Scult, Matthew A.; Dickinson, Dwight; Straub, Richard E.; Donohoe, Gary J.; Morris, Derek W.; Corvin, Aiden; Gill, Michael; Hariri, Ahmad; Weinberger, Daniel R.; Pendleton, Neil; Bitsios, Panos; Rujescu, Dan; Lahti, Jari; Le Hellard, Stephanie; Keller, Matthew C.; Andreassen, Ole Andreas; Deary, Ian John; Glahn, David C.; Malhotra, Anil K.; Lencz, Todd. 2017. GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report form the COGENT consortium. Molecular Psychiatry. 336-345.
  • Jensen, Jacob Malte; Villesen, Palle; Friborg, Rune Møllegaard; Espeseth, Thomas; Le Hellard, Stephanie; Mailund, Thomas; Besenbacher, Søren; Schierup, Mikkel Heide. 2017. Assembly and analysis of 100 full MHC haplotypes from the Danish population. Genome Research. 1597-1607.
  • Polushina, Tatiana; Giddaluru, Sudheer; Bettella, Francesco; Espeseth, Thomas; Lundervold, Astri; Djurovic, Srdjan; Cichon, Sven; Hoffmann, P; Nöthen, Markus M; Steen, Vidar Martin; Andreassen, Ole Andreas; Le Hellard, Stephanie. 2017. Analysis of the joint effect of SNPs to identify independent loci and allelic heterogeneity in schizophrenia GWAS data. Translational psychiatry.
  • Li, Dong; Chang, Xiao; Connolly, John J.; Tian, Lifeng; Liu, Yichuan; Bhoj, Elizabeth J.; Robinson, Nora; Abrams, Debra; Li, Yun R.; Bradfield, Jonathan P.; Kim, Cecilia E.; Li, Jin; Wang, Fengxiang; Snyder, James; Lemma, Maria; Hou, Cuiping; Wei, Zhi; Guo, Yiran; Qiu, Haijun; Mentch, Frank D.; Thomas, Kelly A.; Chiavacci, Rosetta M.; Cone, Roger; Li, Bingshan; Sleiman, Patrick A.; Hakonarson, Hakon; Reichborn-Kjennerud, Ted; Knudsen, Gun Peggy; Andreassen, Ole Andreas; Espeseth, Thomas; Huckins, Laura M; Reinvang, Ivar; Steen, Vidar Martin; Le Hellard, Stephanie; Mattingsdal, Morten; Tozzi, Federica; Kiezebrink, Kirsty; Hebebrand, Johannes; Gorwood, Philip; Adan, Roger A H; Kas, Martien J H; Favaro, Angela; Santonastaso, Paolo; Fernande-Aranda, Fernando; Gratacos, Monica; Rybakowski, Filip; Dmitrzak-Weglarz, Monika; Kaprio, Jaakko; Keski-Rahkonen, Anna; Raevuori-Helkamaa, Anu; Furth, Eric F Van; Slof-Opt Landt, Margarita C T; Hudson, James I; Reichborn-Kjennerud, Ted; Knudsen, Gun Peggy S; Monteleone, Palmiero; Karwautz, Andreas; Berrettini, Wade H; Schork, Nicholas J; Ando, Tetsuya; Inoko, Hidetoshi; Esko, Tonu; Fischer, Krista; Mannik, Katrin; Metspalu, Andres; Baker, Jessica H; DeSocio, Janiece E; Hilliard, Christopher E; O'Toole, Julie K; Pantel, Jacques; Szatkiewicz, Jin P; Zerwas, Stephanie; Davis, Oliver S P; Helder, Sietske; Buhren, Katharina; Burghardt, Roland; De Zwaan, Martina; Egberts, Karin; Ehrlich, Stefan; Herpertz-Dahlmann, Beate; Herzog, Wolfgang; Imgart, Hartmut; Scherag, Andre; Zipfel, Stephan; Boni, Claudette; Ramoz, Nicolas; Versini, Audrey; Danner, Unna N; Hendriks, Judith; Koeleman, Bobby P C; Ophoff, Roel A; Strengman, Eric; Van Elburg, Annemarie A; Bruson, Alice; Clementi, Maurizio; Degortes, Daniela; Forzan, Monica; Tenconi, Elena; Docampo, Elisa; Escaramis, Georgia. 2017. A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling. Scientific Reports. 1-9.
  • Athanasiu, Lavinia; Giddaluru, Sudheer; Neto, Carla Patricia Duarte Fernande; Christoforou, Andrea; Reinvang, Ivar; Lundervold, Astri; Nilsson, Lars-Göran; Kauppi, Karolina; Adolfsson, Rolf; Eriksson, Elias; Sundet, Kjetil Søren; Djurovic, Srdjan; Espeseth, Thomas; Nyberg, Lars Erik; Steen, Vidar Martin; Andreassen, Ole Andreas; Le Hellard, Stephanie. 2017. A genetic association study of CSMD1 and CSMD2 with cognitive function. Brain, behavior, and immunity. 209-216.
  • Adams, Hieab H.H.; Hibar, Derrek; Chouraki, Vincent; Stein, Jason L.; Nyquist, Paul A.; Renteriá, Miguel E.; Trompet, Stella; Arias-Vasquez, Alejandro; Seshadri, Sudha; Desrivieres, Sylvane; Beecham, Ashley H.; Jahanshad, Neda; Wittfeld, Katharina; Van Der Lee, Sven J.; Abramovic, Lucija; Alhusaini, Saud; Amin, Najaf; Andersson, Micael; Arfanakis, Konstantinos; Aribisala, Benjamin S.; Armstrong, Nicola J.; Athanasiu, Lavinia; Axelsson, Tomas; Beiser, Alexa; Bernard, Manon; Bis, Joshua C.; Blanken, Laura M.E.; Blanton, Susan H.; Bohlken, Marc M.; Boks, Marco P.; Bralten, Janita; Brickman, Adam M.; Carmichael, Owen; Chakravarty, M. Mallar; Chauhan, Ganesh; Chen, Qiang; Ching, Christopher R.K.; Cuellar-Partida, Gabriel; Braber, Anouk Den; Doan, Nhat Trung; Ehrlich, Stefan; Filippi, Irina; Ge, Tian; Giddaluru, Sudheer; Goldman, Aaron L.; Gottesman, Rebecca F.; Greven, Corina U.; Grimm, Oliver; Griswold, Michael E.; Guadalupe, Tulio; Hass, Johanna; Haukvik, Unn Kristin H.; Hilal, Saima; Hofer, Edith; Hoehn, David; Holmes, Avram J.; Hoogman, Martine; Janowitz, Deborah; Jia, Tianye; Kasperaviciute, Dalia; Kim, Sungeun; Klein, Marieke; Kraemer, Bernd; Lee, Phil H.; Liao, Jiemin; Liewald, David C.M.; Lopez, Lorna M.; Luciano, Michelle; Macare, Christine; Marquand, Andre; Matarin, Mar; Mather, Karen A.; Mattheisen, Manuel; Mazoyer, Bernard; McKay, David R.; McWhirter, Rebekah; Milaneschi, Yuri; Mirza-Schreiber, Nazanin; Muetzel, Ryan L.; Maniega, Susana Munoz; Nho, Kwangsik; Nugent, Allison C.; Loohuis, Loes M. Olde; Oosterlaan, Jaap; Papmeyer, Martina; Pappa, Irene; Pirpamer, Lukas; Pudas, Sara; Putz, Benno; Rajan, Kumar B.; Ramasamy, Adaikalavan; Richards, Jennifer S.; Risacher, Shannon L.; Roiz-Santianez, Roberto; Rommelse, Nanda; Rose, Emma J.; Royle, Natalie A.; Rundek, Tatjana; Sämann, Philipp G.; Satizabal, Claudia L. 2016. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience. 1569-1582.
  • Athanasiadis, Georgios; Cheng, Jade Y.; Vilhjálmsson, Bjarni J.; Jørgensen, Frank G.; Als, Thomas D.; Le Hellard, Stephanie; Espeseth, Thomas; Sullivan, Patrick F.; Hultman, Christina M.; Kjærgaard, Peter C.; Schierup, Mikkel H.; Mailund, Thomas. 2016. Nationwide genomic study in Denmark reveals remarkable population homogeneity. Genetics. 711-722.
  • Howrigan, Dave; Simonson, M.A.; Davies, Gail; Harris, SE; Tenesa, A.; Starr, JM; Liewald, DC; Deary, IJ; McRae, A.; Wright, MJ; Montgomery, GW; Hansell, Narelle K; Martin, NG; Payton, A.; Horan, M.; Ollier, W.; Abdellaoui, A.; Boomsma, DI; Derosse, P; Knowles, Emma; Glahn, David C.; Djurovic, Srdjan; Melle, Ingrid; Andreassen, Ole Andreas; Christoforou, Andrea; Steen, Vidar Martin; Le Hellard, Stephanie; Sundet, Kjetil Søren; Reinvang, Ivar; Espeseth, Thomas; Lundervold, Astri; Giegling, I; Konte, B; Hartmann, AM; Rujesco, D.; Roussos, P; Giakoumaki, S; Burdick, KE; Bitsios, P; Donohoe, G; Corley, Robin P; Visscher, PM; Pendleton, N.; Malhotra, AK; Neale, BM; Lencz, T; Keller, M. 2016. Genome-wide autozygosity is associated with lower general cognitive ability. Molecular Psychiatry. 837-843.
  • Giddaluru, Sudheer; Espeseth, Thomas; Salami, Alireza; Westlye, Lars Tjelta; Lundquist, Anders; Christoforou, Andrea; Cichon, Sven; Adolfsson, Rolf; Steen, Vidar Martin; Reinvang, Ivar; Nilsson, Lars Göran; Le Hellard, Stephanie; Nyberg, Lars Erik. 2016. Genetics of structural connectivity and information processing in the brain. Brain Structure and Function. 4643-4661.
  • Steen, Vidar Martin; Skrede, Silje; Polushina, Tatiana; López, Miguel; Andreassen, Ole Andreas; Fernø, Johan; Le Hellard, Stephanie. 2016. Genetic evidence for a role of the SREBP transcription system and lipid biosynthesis in schizophrenia and antipsychotic treatment. European Neuropsychopharmacology. 589-598.
  • Qian, Peng; Schork, Andrew J.; Bartsch, Hauke; Lo, Min-Tzu; Panizzon, Matthew S.; Westlye, Lars Tjelta; Kremen, William S.; Jernigan, Terry L.; Le Hellard, Stephanie; Steen, Vidar Martin; Espeseth, Thomas; Huentelman, Matt; Håberg, Asta; Agartz, Ingrid; Djurovic, Srdjan; Andreassen, Ole Andreas; Dale, Anders; Schork, Nicholas J.; Chen, Chi-Hua; Schork, Nicholas J. 2016. Conservation of Distinct Genetically-Mediated Human Cortical Pattern. PLoS Genetics. 18 pages.
  • Thun, Eirunn; Le Hellard, Stephanie; Osland, Teresa Maria; Bjorvatn, Bjørn; Moen, Bente Elisabeth; Magerøy, Nils; Steen, Vidar Martin; Giddaluru, Sudheer; Brattbakk, Hans-Richard; Pallesen, Ståle. 2016. Circadian clock gene variants and insomnia, sleepiness, and shift work disorder. Sleep and Biological Rhythms. 55-62.
  • Chen, Chi-Hua; Peng, Qian; Schork, Andrew J.; Lo, Min-Tzu; Fan, Chun-Chieh; Wang, Yunpeng; Desikan, Rahul S.; Bettella, Franscesco; Hagler, Donald J.; Westlye, Lars Tjelta; Kremen, William S.; Jernigan, Terry L.; Le Hellard, Stephanie; Steen, Vidar Martin; Espeseth, Thomas; Huentelman, Matt; Håberg, Asta; Agartz, Ingrid; Djurovic, Srdjan; Andreassen, Ole Andreas; Schork, Nicholas; Dale, Anders. 2015. Large-scale genomics unveil polygenic architecture of human cortical surface area. Nature Communications.
  • Trampush, Joey W.; Lencz, Todd; Knowles, Emma; Davies, Gail; Guha, Saurav; Pe'er, Itsik; Liewald, David Cherry McLachlan; Starr, John M.; Djurovic, Srdjan; Melle, Ingrid; Sundet, Kjetil Søren; Christoforou, Andrea; Reinvang, Ivar; Mukherjee, Semanti; DeRosse, Pamela; Lundervold, Astri; Steen, Vidar Martin; John, Majnu; Espeseth, Thomas; Räikkönen, Katri; Widen, Elisabeth; Palotie, Aarno; Eriksson, Johan G.; Giegling, Ina; Konte, Bettina; Ikeda, Masashi; Roussos, Panos; Giakoumaki, Stella; Burdick, Katherine E.; Payton, Antony; Ollier, William; Horan, Mike; Scult, Matthew; Dickinson, Dwight; Straub, Richard E.; Donohoe, Gary; Morris, Derek; Corvin, Aiden; Gill, Michael; Hariri, Ahmad R.; Weinberger, Daniel R.; Pendleton, Neil; Iwata, Nakao; Darvasi, Ariel; Bitsios, Panos; Rujescu, Dan; Lahti, Jari; Le Hellard, Stephanie; Keller, Matthew C.; Andreassen, Ole Andreas; Deary, Ian J.; Glahn, David C.; Malhotra, Anil K. 2015. Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 363-373.
  • Davies, Gail; Armstrong, N; Bis, JC; Bressler, J; Chouraki, V; Giddaluru, Sudheer; Hofer, E; Ibrahim-Verbaas, CA; Kirin, M; Lahti, J; Van Der Lee, SJ; Le Hellard, Stephanie; Liu, T; Marioni, RE; Oldmeadow, C; Postmus, I; Smith, AV; Smith, JA; Thalamuthu, A; Thomson, R; Vitart, V; Wang, J; Yu, L; Zgaga, L; Zhao, W; Boxall, R; Harris, SE; Hill, WD; Liewald, DC; Luciano, M; Adams, H; Ames, D; Amin, N; Amouyel, P; Assareh, AA; Au, R; Becker, JT; Beiser, A; Berr, C; Bertram, L; Boerwinkle, E; Buckley, BM; Campbell, H; Corley, J; De Jager, PL; Dufouil, C; Eriksson, JG; Espeseth, Thomas; Faul, JD; Ford, I; Scotland, Generation; Gottesman, RF; Griswold, ME; Gudnason, V; Harris, TB; Heiss, G; Hofman, A; Holliday, EG; Huffman, J; Kardia, SLR; Kochan, N; Knopman, DS; Kwok, JB; Lambert, JC; Lee, T; Li, G; Li, SC; Loitfelder, M; Lopez, OL; Lundervold, Astri; Lundqvist, A; Mather, KA; Mirza, SS; Nyberg, L; Oostra, BA; Palotie, A; Papenberg, G; Pattie, A; Petrovic, K; Polasek, O; Psaty, BM; Redmond, P; Reppermund, S; Rotter, JI; Schmidt, H; Schuur, M; Schofield, PW; Scott, RJ; Steen, Vidar Martin; Stott, DJ; Van Swieten, JC; Taylor, KD; Trollor, J; Trompet, S; Uitterlinden, AG; Weinstein, G; Widen, E; Windham, BG; Jukema, JW; Wright, AF. 2015. Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949). Molecular Psychiatry. 183-192.
  • Hansell, Narelle K.; Halford, Graeme S.; Andrews, Glenda; Shum, David H.K.; Harris, Sarah E.; Davies, Gail; Franic, Sanja; Christoforou, Andrea; Zietsch, Brendan; Painter, Jodie; Medland, Sarah E.; Ehli, Erik A.; Davies, Gareth E.; Steen, Vidar Martin; Lundervold, Astri; Reinvang, Ivar; Montgomery, Grant W.; Espeseth, Thomas; Pol, Hilleke E. Hulshoff; Starr, John M.; Martin, Nicholas G.; Le Hellard, Stephanie; Boomsma, Dorret I.; Deary, Ian J.; Wright, Margaret J. 2015. Genetic basis of a cognitive complexity metric. PLOS ONE.
  • Myrum, Craig; Giddaluru, Sudheer; Jacobsen, Kaya Kvarme; Espeseth, Thomas; Nyberg, Lars; Lundervold, Astri; Haavik, Jan; Nilsson, Lars-Göran; Reinvang, Ivar; Steen, Vidar Martin; Johansson, Stefan; Wibrand, Karin; Le Hellard, Stephanie; Bramham, Clive R. 2015. Common variants in the ARC gene are not associated with cognitive abilities. Brain and Behavior. 8 pages.
  • Hibar, Derrek; Stein, Jason L; Renteria, Miguel E; Arias-Vasquez, Alejandro; Desrivieres, Sylvane; Jahanshad, Neda; Toro, Roberto; Wittfeld, Katharina; Abramovic, Lucija; Andersson, Micael; Aribisala, Benjamin S; Armstrong, Nicola J; Bernard, Manon; Bohlken, Marc M; Boks, Marco P; Bralten, Janita; Brown, Andrew; Mallar Chakravarty, M; Chen, Qiang; Ching, Christopher R K; Cuellar-Partida, Gabriel; Den Braber, Anouk; Giddaluru, Sudheer; Goldman, Aaron L; Grimm, Oliver; Guadalupe, Tulio; Hass, Johanna; Woldehawariat, Girma; Holmes, Avram J; Hoogman, Martine; Janowitz, Deborah; Jia, Tianye; Kim, Sungeun; Klein, Marieke; Kraemer, Bernd; Lee, Phil H; Olde Loohuis, Loes M; Luciano, Michelle; MacAre, Christine; Mather, Karen A; Mattheisen, Manuel; Milaneschi, Yuri; Nho, Kwangsik; Papmeyer, Martina; Ramasamy, Adaikalavan; Risacher, Shannon L; Roiz-Santianez, Roberto; Rose, Emma J; Salami, Alireza; Sämann, Philipp G; Schmaal, Lianne; Schork, Andrew J; Shin, Jean; Strike, Lachlan T; Teumer, Alexander; Van Donkelaar, Marjolein M J; Van Eijk, Kristel R; Walters, Raymond K; Westlye, Lars Tjelta; Whelan, Christopher D; Winkler, Anderson M; Zwiers, Marcel P; Alhusaini, Saud; Athanasiu, Lavinia; Ehrlich, Stefan; Hakobjan, Marina M H; Hartberg, Cecilie Bhandari; Haukvik, Unn Kristin H.; Heister, Angelien J G A M; Hoehn, David; Kasperaviciute, Dalia; Liewald, David C M; Lopez, Lorna M; Makkinje, Remco R R; Matarin, Mar; Naber, Marlies A M; Reese McKay, D; Needham, Margaret; Nugent, Allison C; Putz, Benno; Royle, Natalie A; Shen, Li; Sprooten, Emma; Trabzuni, Daniah; Van Der Marel, Saskia S L; Van Hulzen, Kimm J E; Walton, Esther; Wolf, Christiane; Almasy, Laura; Ames, David; Arepalli, Sampath; Assareh, Amelia A; Bastin, Mark E; Brodaty, Henry; Bulayeva, Kazima B; Carless, Melanie A; Cichon, Sven; Corvin, Aiden; Curran, Joanne E; Czisch, Michael. 2015. Common genetic variants influence human subcortical brain structures. Nature. 224-229.
  • Thompson, Paul M; Stein, Jason L; Medland, Sarah E; Hibar, Derrek P; Vasquez, Alejandro Arias; Renteria, Miguel E; Toro, Roberto; Jahanshad, Neda; Schumann, Gunter; Franke, Barbara; Wright, Margaret J; Martin, Nicholas G; Agartz, Ingrid; Alda, Martin; Alhusaini, Saud; Almasy, Laura; Almeida, Jorge; Alpert, Kathryn; Andreasen, Nancy C; Andreassen, Ole Andreas; Apostolova, Liana G; Appel, Katja; Armstrong, Nicola J; Aribisala, Benjamin; Bastin, Mark E; Bauer, Michael; Bearden, Carrie E; Bergmann, Ørjan; Binder, Elisabeth B; Blangero, John; Bockholt, Henry J; Bøen, Erlend; Bois, Catherine; Boomsma, Dorret I; Booth, Tom; Bowman, Ian J; Bralten, Janita; Brouwer, Rachel M; Brunner, Han G; Brohawn, David G; Buckner, Randy L; Buitelaar, Jan; Bulayeva, Kazima; Bustillo, Juan R; Calhoun, Vince D; Cannon, Dara M; Cantor, Rita M; Carless, Melanie A; Caseras, Xavier; Cavalleri, Gianpiero L; Chakravarty, M Mallar; Chang, Kiki D; Ching, Christopher RK; Christoforou, Andrea; Cichon, Sven; Clark, Vincent P; Conrod, Patricia; Coppola, Giovanni; Crespo-Facorro, Benedicto; Curran, Joanne E; Czisch, Michael; Deary, Ian J; de Geus, Eco JC; den Braber, Anouk; Delvecchio, Giuseppe; Depondt, Chantal; de Haan, Lieuwe; de Zubicaray, Greig I; Dima, Danai; Dimitrova, Rali; Djurovic, Srdjan; Dong, Hongwei; Donohoe, Gary; Duggirala, Ravindranath; Dyer, Thomas D; Ehrlich, Stefan; Ekman, Carl Johan; Elvsåshagen, Torbjørn; Emsell, Louise; Erk, Susanne; Espeseth, Thomas; Fagerness, Jesen; Fears, Scott; Fedko, Iryna; Fernandez, Guillen; Fisher, Simon E; Foroud, Tatiana; Fox, Peter T; Francks, Clyde; Frangou, Sophia; Frey, Eva Maria; Frodl, Thomas; Frouin, Vincent; Garavan, Hugh; Giddaluru, Sudheer; Glahn, David C; Godlewska, Beata; Goldstein, Rita Z; Gollub, Randy L; Grabe, Hans J. 2014. The ENIGMA Consortium: Large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging and Behavior. 153-182.
  • Lencz, T; Knowles, Emily; Davies, G; Guha, S; Liewald, DC; Starr, JM; Djurovic, Srdjan; Melle, Ingrid; Sundet, Kjetil Søren; Christoforou, Andrea; Reinvang, Ivar; Mukherjee, Sayan; Derosse, P; Lundervold, Arvid; Steen, Vidar Martin; Espeseth, Thomas; John, M.; Räikkönen, K; Widen, E; Palotie, A; Eriksson, JG; Giegling, I; Konte, B; Ikeda, M; Roussos, P; Giakoumaki, S; Burdick, KE; Payton, A.; Ollier, W; Horan, M.; Donohoe, G; Morris, D; Corvin, A; Gill, M; Pendleton, N; Iwata, N; Darvasi, A; Bitsios, P; Rujescu, D; Lahti, J; Le Hellard, Stephanie; Keller, MC; Andreassen, Ole Andreas; Deary, IJ; Glahn, DC; Malhotra, AK. 2014. Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: A report from the Cognitive Genomics consorTium (COGENT). Molecular Psychiatry. 168-174.
  • Duarte Fernandes, Carla; Westlye, Lars Tjelta; Giddaluru, Sudheer; Christoforou, Andrea; Kauppi, Karolina; Adolfsson, Rolf; Nilsson, Lars-Göran; Nyberg, Lars; Lundervold, Astri ; Reinvang, Ivar; Steen, Vidar Martin; Le Hellard, Stephanie; Espeseth, Thomas. 2014. Lack of association of the rs1344706 ZNF804A variant with cognitive functions and DTI indices of white matter microstructure in two independent healthy populations. Psychiatry Research : Neuroimaging. 60-66.
  • Hill, Wayne David; Davies, Gail; Van De Lagemaat, Louie N.; Christoforou, Andrea; Marioni, Riccardo R.; Duarte Fernandes, Carla; Liewald, David Cherry; Croning, Mike D.R.; Payton, Anthony; Craig, Leone C.A.; Whalley, Lawrence J.; Horan, Michael; Ollier, William E.R.; Hansell, Narelle K.; Wright, Margaret J.; Martin, Nicholas G.; Montgomery, Grant W.; Steen, Vidar Martin; Le Hellard, Stephanie; Espeseth, Thomas; Lundervold, Astri ; Reinvang, Ivar; Starr, John M.; Pendleton, Neil; Grant, Seth G.N.; Bates, Timothy C.; Deary, Ian John. 2014. Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins. Translational psychiatry.
  • Le Hellard, Stephanie; Steen, Vidar Martin. 2014. Genetic architecture of cognitive traits. Scandinavian Journal of Psychology. 255-262.
  • Christoforou, Andrea; Espeseth, Thomas; Davies, Gail L.; Duarte Fernandes, Carla; Giddaluru, Sudheer; Mattheisen, Manuel; Tenesa, Albert; Harris, Sarah E.; Liewald, David C; Payton, Anthony; Ollier, William E.R.; Horan, Michael Arthur; Pendleton, Neil; Haggarty, Paul; Djurovic, Srdjan; Herms, Stefan; Hoffmann, Per; Cichon, Sven; Lundervold, Astri; Starr, John M; Reinvang, Ivar; Steen, Vidar Martin; Deary, Ian J; Le Hellard, Stephanie. 2014. GWAS-based pathway analysis differentiates between fluid and crystallized intelligence. Genes, Brain and Behavior.
  • Norheim, Katrine Brække; Le Hellard, Stephanie; Nordmark, Gunnel; Harboe, Erna; Gøransson, Lasse G; Brun, Johan G; Marie, Wahren-Herlenius; Jonsson, Roland; Omdal, Roald. 2014. A possible genetic association with chronic fatigue in primary Sjögren’s syndrome: a candidate gene study. Rheumatology International. 191-197.
  • Reichborn-Kjennerud, Ted; Knudsen, Gun Peggy; Andreassen, Ole Andreas; Espeseth, Thomas; Lundervold, Astri; Reinvang, Ivar; Steen, Vidar Martin; Le Hellard, Stephanie; Mattingsdal, Morten; Boraske, V; Franklin, CS; Floyd, James A. B.; Thornton, Laura M; Huckins, L. M.; Southam, L; Rayner, NW; Tachmazidou, I; Klump, KL; Treasure, Jim; Lewis, C. M.; Schmidt, U; Tozzi, F; Kiezebrink, K; Hebebrand, J.; Gorwood, P.; Adan, R. A. H.; Kas, M. J. H.; Favaro, A; Santonastaso, P; Fernández-Aranda, Fernando; Gratacòs, Mònica; Rybakowski, Finn; Dmitrzak-Weglarz, M.; Kaprio, J; Keski-Rahkonen, A; Raevuori, A.; Van Furth, E. F.; Slof-Op 't Landt, M. C. T.; Hudson, JI; Monteleone, P.; Kaplan, AS; Karwautz, A; Hakonarson, H; Berrettini, W. H.; Guo, Y; Li, D; Schork, NJ; Komaki, G; Ando, T; Inoko, H. 2014. A genome-wide association study of anorexia nervosa. Molecular Psychiatry. 1085-1094.
  • Haldorsen, Karstein; Appel, Silke; Le Hellard, Stephanie; Bruland, Ove; Brun, Johan G; Omdal, Roald; Kristjansdottir, Gudlaug; Theander, Elke; Duarte Fernandes, Carla; Kvarnström, Marika; Eriksson, Per; Rönnblom, Lars; Herlenius, Maria Wahrén; Nordmark, Gunnel; Jonsson, Roland; Bolstad, Anne Isine. 2013. No association of primary Sjögren's syndrome with Fcγ receptor gene variants. Genes and Immunity. 234-237.
  • Duarte Fernandes, Carla; Christoforou, Andrea; Giddaluru, Sudheer; Ersland, Kari Merete; Djurovic, Srdjan; Mattheisen, Manuel; Lundervold, Astri ; Reinvang, Ivar; Nöthen, Markus M.; Rietschel, Marcella; Ophoff, Roel A.; Hofman, Albert; Uitterlinden, André G.; Werge, Thomas; Cichon, Sven; Espeseth, Thomas; Andreassen, Ole Andreas; Steen, Vidar Martin; Le Hellard, Stephanie. 2013. A genetic deconstruction of neurocognitive traits in schizophrenia and bipolar disorder. PLOS ONE. 9 pages.
  • Christoforou, Andrea; Dondrup, Michael; Mattingsdal, Morten; Mattheisen, Manuel; Giddaluru, Sudheer; Nöthen, Markus M.; Rietschel, Marcella; Cichon, Sven; Djurovic, Srdjan; Andreassen, Ole Andreas; Jonassen, Inge; Steen, Vidar Martin; Puntervoll, Pål; Le Hellard, Stephanie. 2012. Linkage-disequilibrium-based binning affects the interpretation of GWASs. American Journal of Human Genetics. 727-733.
  • Espeseth, Thomas; Christoforou, Andrea; Lundervold, Astri ; Steen, Vidar Martin; Le Hellard, Stephanie; Reinvang, Ivar. 2012. Imaging and cognitive genetics: the Norwegian Cognitive NeuroGenetics Sample. Twin Research and Human Genetics. 442-452.
  • Stein, Jason L; Medland, Sarah E; Vasquez, Alejandro Arias; Hibar, Derrek P; Senstad, Rudy E; Winkler, Anderson M; Toro, Roberto; Appel, Katja; Bartecek, Richard; Bergmann, Ørjan; Bernard, Manon; Cannon, Dara M; Chakravarty, Mallar; Christoforou, Andrea; Domin, Martin; Grimm, Oliver; Hollinshead, Marisa; Holmes, Avran; Homuth, Georg; Hottenga, Jouke-Jan; Langan, Camilla; Lopez, Lorna M; Hansel, Narelle K; Hwang, Kristy S.; Kim, Sungeun; Laje, Gonzalo; Lee, Phil H; Liu, Xinmin; Loth, Eva; Lourdusamy, Anbarasu; Mattingsdal, Morten; Mohnke, Sebastian; Maniega, Susana Muñoz; Nho, Kwangsik; Nugent, Allison C; O’Brien, Carol; Papmeyer, Martina; Pütz, Benno; Ramasamy, Adaikalavan; Rasmussen, Jerod; Rijpkema, Mark; Risacher, Shannon L; Roddey, J Cooper; Rose, Emma; Ryten, Mina; Shen, Li; Sprooten, Emma; Strengman, Eric; Teumer, Alexander; Trabzuni, Daniah; Turner, Jessica; van Eijk, Kristel; van Erp, Theo G M; van Tol, Marie-Jose; Wittfeld, Katharina; Wolf, Christiane; Woudstra, Saskia; Aleman, Andre; Alhusaini, Saud; Almasy, Laura; Binder, Elisabeth B; Brohawn, David G; Cantor, Rita M; Carless, Melanie A; Corvin, Aiden; Czisch, Michael; Curran, Joanne E; Davies, Gail; de Almeida, Marcio A A; Delanty, Norman; Depondt, Chantal; Duggirala, Ravi; Dyer, Thomas D.; Erk, Susanne; Fagerness, Jesen; Fox, Peter T; Freimer, Nelson B.; Gill, Michael; Göring, Harald H H; Hagler, Donald J.; Hoehn, David; Holsboer, Florian; Hoogman, Martine; Hosten, Norbert; Jahanshad, Neda; Johnson, Matthew p.; Kasperaviciute, Dalia; Kent Jr, Jack W; Kochunov, Peter; Lancaster, Jack L; Lawrie, Stephen M; Liewald, David C; Mandl, René; Matarin, Mar; Mattheisen, Manuel; Meisenzahl, Eva; Melle, Ingrid; Moses, Eric K; Mühleisen, Thomas W.; Nauck, Matthias. 2012. Identification of common variants associated with human hippocampal and intracranial volumes. Nature Genetics. 552-561.
  • Ersland, Kari Merete; Christoforou, Andrea; Stansberg, Christine; Espeseth, Thomas; Mattheisen, Manuel; Mattingsdal, Morten; Hardarson, Gudmundur A.; Hansen, Thomas; Duarte Fernandes, Carla; Giddaluru, Sudheer; Breuer, Rene; Strohmaier, Jana; Djurovic, Srdjan; Nöthen, Markus M.; Rietschel, Marcella; Lundervold, Astri ; Werge, Thomas; Cichon, Sven; Andreassen, Ole Andreas; Reinvang, Ivar; Steen, Vidar Martin; Le Hellard, Stephanie. 2012. Gene-based analysis of regionally enriched cortical genes in GWAS data sets of cognitive traits and psychiatric disorders. PLOS ONE. 14 pages.
  • Håvik, Bjarte; Degenhardt, Franziska A.; Johansson, Stefan; Duarte Fernandes, Carla; Hinney, Anke; Scherag, André; Lybæk, Helle; Djurovic, Srdjan; Christoforou, Andrea; Ersland, Kari; Giddaluru, Sudheer; O'Donovan, Michael C.; Owen, Michael J.; Craddock, Nick; Mühleisen, Thomas W.; Mattheisen, Manuel; Schimmelmann, Benno G.; Renner, Tobias J.; Warnke, Andreas; Herpertz-Dahlmann, Beate; Sinzig, Judith; Albayrak, Özgür; Rietschel, Marcella; Nöthen, Markus M.; Bramham, Clive R.; Werge, Thomas; Hebebrand, Johannes; Haavik, Jan; Andreassen, Ole Andreas; Cichon, Sven; Steen, Vidar Martin; Le Hellard, Stephanie. 2012. DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder. PLOS ONE. 12 pages.
  • Bolstad, Anne Isine; Le Hellard, Stephanie; Kristjansdottir, Gudlaug; Vasaitis, Lillian; Kvarnström, Marika; Sjöwall, Christopher; Johnsen, Svein Joar Auglæn; Eriksson, Per; Omdal, Roald; Brun, Johan G; Wahren-Herlenius, Marie; Theander, Elke; Syvänen, Ann-Christine; Rönnblom, Lars; Nordmark, Gunnel; Jonsson, Roland. 2012. Association between genetic variants in the tumour necrosis factor/lymphotoxin alpha/lymphotoxin beta locus and primary Sjogren's syndrome in Scandinavian samples. Annals of the Rheumatic Diseases. 981-988.
  • Håvik, Bjarte; Le Hellard, Stephanie; Rietschel, Marcella; Lybæk, Helle; Djurovic, Srdjan; Mattheisen, Manuel; Mühleisen, Thomas W.; Degenhardt, Franziska A.; Priebe, Lutz; Maier, Wolfgang; Breuer, Rene; Schulze, Thomas G.; Agartz, Ingrid; Melle, Ingrid; Hansen, Thomas; Bramham, Clive R. Evjen; Nöthen, Markus M.; Stevens, Beth; Werge, Thomas; Andreassen, Ole Andreas; Cichon, Sven; Steen, Vidar Martin. 2011. The Complement Control-Related Genes CSMD1 and CSMD2 Associate to Schizophrenia. Biological Psychiatry. 35-42.
  • Appel, Silke; Le Hellard, Stephanie; Bruland, Ove; Brun, Johan G; Omdal, Roald; Kristjansdottir, Gudlaug; Theander, Elke; Nordmark, Gunnel; Kvarnström, Marika; Eriksson, Per; Rönnblom, Lars; Wahren-Herlenius, Marie; Jonsson, Roland. 2011. Potential association of muscarinic receptor 3 gene variants with primary Sjögren's syndrome. Annals of the Rheumatic Diseases. 1327-1329.
  • Fernø, Johan; Skrede, Silje; Vik-Mo, Audun Osland; Jassim, Goran; Le Hellard, Stephanie; Steen, Vidar Martin. 2011. Lipogenic effects of psychotropic drugs: focus on the SREBP system. Frontiers in Bioscience. 49-60.
  • Davies, G.; Tenesa, A.; Payton, A.; Yang, J.; Harris, Sarah E.; Liewald, D.; Ke, X.; Le Hellard, Stephanie; Christoforou, Andrea; Luciano, Michelle; McGhee, K.; Lopez, L.; Gow, Alan J.; Corley, J.; Redmond, P.; Fox, Helen C.; Haggarty, Paul; Whalley, Lawrence J.; McNeill, Geraldine; Goddard, Mike E.; Espeseth, Thomas; Lundervold, Astri ; Reinvang, Ivar; Pickles, Andrew; Steen, Vidar Martin; Ollier, W.; Porteous, David J.; Horan, Maeve; Starr, John M.; Pendleton, N.; Visscher, Peter M.; Deary, Ian J. 2011. Genome-wide association studies establish that human intelligence is highly heritable and polygenic. Molecular Psychiatry. 996-1005.
  • Jassim, Goran; Fernø, Johan; Theisen, Frank M.; Haberhausen, Michael; Christoforou, Andrea; Håvik, Bjarte; Gebhardt, Stefan; Remschmidt, Helmut; Mehler-Wex, Claudia; Hebebrand, Johannes; Le Hellard, Stephanie; Steen, Vidar Martin. 2011. Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia. Pharmacopsychiatry. 15-20.
  • Le Hellard, Stephanie; Mühleisen, Thomas W.; Djurovic, Srdjan; Fernø, Johan; Ouriaghi, Zohra; Mattheisen, Manuel; Vasilescu, Catalina; Ræder, Maria Therese Barøy; Hansen, Thomas; Strohmaier, Jana; Georgi, Alexander; Brockschmidt, Felix F.; Melle, Ingrid; Nenadic, Igor; Sauer, Heinrich; Rietschel, Marcella; Nöthen, Markus M.; Werge, Thomas; Andreassen, Ole Andreas; Cichon, Sven; Steen, Vidar Martin. 2010. Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples. Molecular Psychiatry. 463-472.
  • Le Hellard, Stephanie; Håvik, Bjarte; Espeseth, Thomas; Breilid, Harald; Løvlie, Roger; Luciano, Michelle; Gow, Alan J.; Harris, Sarah E.; Starr, John M.; Wibrand, Karin; Lundervold, Astri ; Porteous, David J.; Bramham, Clive R. Evjen; Deary, Ian J.; Reinvang, Ivar; Steen, Vidar Martin. 2009. Variants in doublecortin- and calmodulin kinase like 1, a gene up-regulated by BDNF, are Associated with memory and general cognitive abilities. PLOS ONE.
  • Djurovic, Srdjan; Le Hellard, Stephanie; Kähler, Anna Katarina; Jönsson, Erik G.; Agartz, Ingrid; Steen, Vidar Martin; Hall, Håkan; Wang, August G.; Rasmussen, Henrik B.; Melle, Ingrid; Werge, Thomas; Andreassen, Ole Andreas. 2009. Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE). Psychiatry Research. 256-258.
  • Le Hellard, Stephanie; Theisen, Frank M.; Haberhausen, Michael; Ræder, Maria Therese Barøy; Fernø, Johan; Gebhardt, Stefan; Hinney, Anke; Remschmidt, Helmut; Krieg, Jürgen-Christian; Mehler-Wex, Claudia; Nöthen, Markus M.; Hebebrand, Johannes; Steen, Vidar Martin. 2009. Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects? Molecular Psychiatry. 308-317.
  • Djurovic, Srdjan; Kähler, Anna Katarina; Kulle, Bettina; Jönsson, Erik G.; Agartz, Ingrid; Le Hellard, Stephanie; Hall, Håkan; Jakobsen, Klaus Damsgaard; Hansen, Torben; Melle, Ingrid; Werge, Thomas; Steen, Vidar Martin; Andreassen, Ole Andreas. 2009. A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE). Schizophrenia Research. 242-248.
  • Le Hellard, S; Muhleisen, TW; Djurovic, Srdjan; Fernø, J; Ouriaghi, Z; Mattheisen, M; Vasilescu, C; Raeder, MB; Hansen, T; Strohmaier, J; Georgi, A; Brockschmidt, FF; Melle, I; Nenadic, I; Sauer, H; Rietschel, M; Nothen, MM; Werge, T; Andreassen, Ole Andreas; Cichon, S; Steen, VM. 2008. Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples. Molecular Psychiatry.
  • Le Hellard, Stephanie; Theisen, F.M.; Haberhausen, M; Ræder, Maria Therese Barøy; Fernø, Johan; Gebhardt, S; Hinney, A.; Remschmidt, H.; Krieg, J.C.; Mehler-Wex, C.; Nöthen, Markus M.; Hebebrand, J.; Steen, Vidar Martin. 2008. Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: pertubation of SREBP-controlled lipogenesis in drug-realted metabolic adverse effects? Molecular Psychiatry. 308-317.
  • Djurovic, Srdjan; Kähler, Anna Katarina; Kulle, Bettina; Jõnsson, EG; Agartz, Ingrid; Le Hellard, S; Hall, H; Jakobsen, KD; Hansen, T; Melle, Ingrid; Werge, T; Steen, VM; Andreassen, Ole Andreas. 2008. A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE). Schizophrenia Research.
Reader opinion piece
  • Lam, Max; Trampush, Joey W.; Yu, Jin; Knowles, Emma; Djurovic, Srdjan; Melle, Ingrid; Sundet, Kjetil Søren; Christoforou, Andrea; Reinvang, Ivar; DeRosse, Pamela; Lundervold, Astri; Steen, Vidar Martin; Espeseth, Thomas; Räikkönen, Katri; Widén, Elisabeth; Palotie, Aarno; Eriksson, Johan G.; Giegling, Ina; Konte, Bettina; Roussos, Panos; Giakoumaki, Stella; Burdick, Katherine E.; Payton, Antony; Ollier, William; Chiba-Falek, Ornit; Attix, Deborah K.; Need, Anna C.; Cirulli, Elizabeth T.; Voineskos, Aristotle N.; Stefanis, Nikos C.; Avramopoulos, Dimitrios; Hatzimanolis, Alex; Arking, Dan E.; Smyrnis, Nikolaos; Bilder, Robert M.; Freimer, Nelson A.; Cannon, Tyrone D.; London, Edythe; Poldrack, Russell A.; Sabb, Fred W.; Congdon, Eliza; Conley, Emily Drabant; Scult, Matthew A.; Dickinson, Dwight; Straub, Richard E.; Donohoe, Gary; Morris, Derek; Corvin, Aiden; Gill, Michael; Hariri, Ahmad R.; Weinberger, Daniel R.; Pendleton, Neil; Bitsios, Panos; Rujescu, Dan; Lahti, Jari; Le Hellard, Stephanie; Keller, Matthew C.; Andreassen, Ole Andreas; Glahn, David C.; Malhotra, Anil K.; Lencz, Todd. 2018. Multi-Trait analysis of gwas and biological insights into cognition: A response to Hill (2018). Twin Research and Human Genetics. 394-397.
  • Christoforou, Andrea; Mattheisen, Manuel; Giddaluru, Sudheer; Steen, Vidar M; Le Hellard, Stephanie. 2012. Response to Zhu et al. American Journal of Human Genetics. 969-970.
  • Christoforou, Andrea; Mattheisen, Manuel; Giddaluru, Sudheer; Steen, Vidar Martin; Le Hellard, Stephanie. 2012. Linkage-Disequilibrium-Based Binning Misleads the Interpretation of Genome-wide Association Studies Response. American Journal of Human Genetics. 969-970.
Doctoral dissertation
  • Tronstad, Rune Rose. 2019. Clinical and molecular effects of guanylate cyclase C-activation.
  • Banerjee, Niladri. 2018. An evolutionary epigenetics approach to schizophrenia.
  • Fernandes, Carla Patricia Duarte. 2015. A genetic study of schizophrenia and bipolar disorder. A cognitive endophenotype approach.
Abstract
  • Steen, Vidar; Le Hellard, Stephanie; Espeseth, Thomas; Lundervold, Astri; Reinvang, Ivar. 2013. Human cognitive ability is influenced by genetic variation in components of postsynaptic signaling complexes assembled by MAGUK proteins. Behavior Genetics. 521-522.
  • Haldorsen, Karstein; Appel, Silke; Le Hellard, Stephanie; Bruland, Ove; Brun, Johan G; Omdal, Roald; Kristjansdottir, Gudlaug; Theander, Elke; Fernandes, Carla P.D.; Nordmark, Gunnel; Kvarnström, Marika; Eriksson, Per; Rönnblom, Lars; Herlenius, Maria Wahrén; Jonsson, Roland; Bolstad, Anne Isine. 2012. No association of primary Sjögren's Syndrome with Fc gamma? Receptor gene variants. Scandinavian Journal of Immunology. 198-198.
  • Haldorsen, Karstein; Appel, Silke; Bruland, Ove; Le Hellard, Stephanie; Brun, Johan G; Omdal, Roald; Kristjansdottir, Gudlaug; Theander, Elke; Nordmark, Gunnel; Kvamstrom, M; Eriksson, P; Rönnblom, Lars; Wahren-Herlenius, Marie; Jonsson, Roland; Bolstad, Anne Isine. 2010. Fc gamma receptor IIA, IIIA and IIIB single nucleotide polymorphisms and Fc gamma receptor IIIB copy number variation: No association with primary Sjögren's syndrome. Scandinavian Journal of Rheumatology. 36-36.
Poster
  • Bolstad, Anne Isine; Le Hellard, Stephanie; Kristjansdottir, GT; Vasaitis, Lillian; Kvarnström, Marika; Sjöwall, Christopher; Auglænd Johnsen, S.J.; Eriksson, P.; Omdal, Roald; Brun, Johan G; Wahren-Herlenius, Marie; Theander, Elke; Syvanen, Ann-Christine; Rönnblom, Lars; Nordmark, Gunnel; Jonsson, Roland. 2011. Association between tumor necrosis factor, lymphotoxin alpha and beta genetic variants and primary Sjögren`s syndrome in Scandinavian samples.
  • Haldorsen, Karstein; Appel, Silke; Bruland, Ove; Le Hellard, Stephanie; Brun, Johan G; Omdal, Roald; Kristjansdottir, Gudlaug; Theander, Elke; Nordmark, Gunnel; Kvarnström, M; Eriksson, Per; Rönnblom, Lars; Wahren-Herlenius, Marie; Jonsson, Roland; Bolstad, Anne Isine. 2009. Fc receptor IIA, IIIA and IIIB single nucleotide polymorphisms and Fc receptor IIIB copy number variation: No association with primary Sjögren’s syndrome.
Academic literature review
  • Le Hellard, Stephanie; Hanson, Isabel. 2012. The Imaging and Cognition Genetics Conference 2011, ICG 2011: A Meeting of Minds.

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See my ORCID page:  https://orcid.org/0000-0002-8085-051X

Phd

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