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Thomas Helland

Staff Engineer
  • E-mailThomas.Helland@uib.no
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • Helland, Thomas; Hagen, Kari Britt; Haugstøyl, Martha Eimstad; Kvaløy, Jan Terje; Lunde, Siri; Lode, Kirsten; Lind, Ragna Anne; Gripsrud, Birgitta Haga; Jonsdottir, Kristin; Gjerde, Jennifer; Bifulco, Ersilia; Hustad, Simon Steinar; Jonassen, Janne; Aas, Turid; Lende, Tone Hoel; Lien, Ernst Asbjørn; Janssen, Emiel; Søiland, Håvard; Mellgren, Gunnar. 2019. Drug monitoring of tamoxifen metabolites predicts vaginal dryness and verifies a low discontinuation rate from the Norwegian Prescription Database. Breast Cancer Research and Treatment. 185-195.
  • Bozickovic, Olivera; Skartveit, Linn; Svendsen, Agnete; Helland, Thomas; Jonsdottir, Kristin; Flågeng, Marianne Hauglid; Fenne, Ingvild Sveinsgjerd; Janssen, Emiel; Lorens, James; Bjørkhaug, Lise; Sagen, Jørn V.; Mellgren, Gunnar. 2018. A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells. Journal of Steroid Biochemistry and Molecular Biology. 57-70.
  • Helland, Thomas; Henne, Nina; Bifulco, Ersilia; Naume, Bjørn; Borgen, Elin; Kristensen, Vessela N.; Kvaløy, Jan Terje; Lash, Timothy L; Grenaker, Grethe Irene; van Schaik, RHN; Janssen, Emiel; Hustad, Simon Steinar; Lien, Ernst Asbjørn; Mellgren, Gunnar; Søiland, Håvard. 2017. Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients. Breast Cancer Research.
  • Ejarque, Miriam; Borlaug, Marianne; Vilarrasa, Núria; Martinez-Perez, Bruno; Megía, Ana; Llauradó, Gemma; Helland, Thomas; Gutierrez, Cristina; Serena, Carolina; Folkestad, Oddry H; Nuñez-Roa, Catalina; Roche, Kelly; Casajoana, Ana; Fradera, Rosa; González-Clemente, José Miguel; López, Miguel; Mohn, Arne-Christian; Nedrebø, Bjørn Gunnar; Nogueiras, Rubén; Mellgren, Gunnar; Fernø, Johan; Fernández-Veledo, Sonia; Vendrell, Joan. 2017. Angiopoietin-like protein 8/betatrophin as a new determinant of type 2 diabetes remission after bariatric surgery. Translational Research: The Journal of Laboratory and Clinical Medicine. 35-44.e4.
  • Helland, Thomas; Gjerde, Jennifer; Dankel, Simon N; Fenne, Ingvild Sveinsgjerd; Skartveit, Linn; Drangevåg, Andreas; Bozickovic, Olivera; Flågeng, Marianne Hauglid; Søiland, Håvard; Mellgren, Gunnar; Lien, Ernst Asbjørn. 2015. The active tamoxifen metabolite endoxifen (4OHNDtam) strongly down-regulates cytokeratin 6 (CK6) in MCF-7 breast cancer cells. PLOS ONE. 19 pages.
  • Bozickovic, Olivera; Hoang, Tuyen; Fenne, Ingvild Sveinsgjerd; Helland, Thomas; Skartveit, Linn; Ouchida, Mamoru; Mellgren, Gunnar; Sagen, Jørn V. 2015. Cyclin C interacts with steroid receptor coactivator 2 and upregulates cell cycle genes in MCF-7 cells. BBA - Molecular Cell Research. 2383-2391.
  • Fenne, Ingvild Sveinsgjerd; Helland, Thomas; Flågeng, Marianne Hauglid; Dankel, Simon E Nitter; Mellgren, Gunnar; Sagen, Jørn V. 2013. Downregulation of steroid receptor coactivator-2 modulates estrogen-responsive genes and stimulates proliferation of MCF-7 breast cancer cells. PLOS ONE. 10 pages.
Doctoral dissertation
  • Helland, Thomas. 2019. Tamoxifen in the treatment of luminal breast cancer. Implications of active metabolites on gene expression, side effects and clinical outcome.
Poster
  • Lunde, Siri; Helland, Thomas; Jonassen, Janne; Martha, Haugstøyl; Austdal, Marie; Lode, Kirsten; Hagen, Kari-Britt; Gripsrud, Birgitta Haga; Lind, Ragna Anne; Gjerde, Jennifer; Lende, Tone Hoel; Gilje, Bjørnar; Aas, Turid; Jonsdottir, Kristin; Kroksveen, Ann Cathrine; Erdal, Bjørg; Vevle, Sissel; Sagen, Jørn-Vegard; Oltedal, Satu; Nordgård, Oddmund; Tjensvoll, Kjersti; Lash, Timothy; Kvaløy, Jan Terje; Janssen, Emiel; Mellgren, Gunnar; Søiland, Håvard; Lien, Ernst Asbjørn. 2018. A prospective, longitudinal, breast cancer biobank (PBCB) in western Norway.
  • Fenne, Ingvild Sveinsgjerd; Flågeng, Marianne Hauglid; Helland, Thomas; Dankel, Simon E Nitter; Mellgren, Gunnar. 2011. Characterization of Global Gene Expression in Breast Cancer Cells after cAMP/PKA-mediated downregulation of Steroid Receptor Coactivator 2.

More information in national current research information system (CRIStin)