Home
Tine Veronica Karlsen's picture

Tine Veronica Karlsen

Associate Professor
  • E-mailTine.Karlsen@uib.no
  • Phone+47 55 58 64 55+47 55 58 64 03
  • Visitor Address
    Jonas Lies vei 91
  • Postal Address
    Postboks 7804
    5020 Bergen
Journal articles
  • Becirovic-Agic, Mediha; Jönsson, Sofia; Tveitarås, Maria Kathrine; Skogstrand, Trude; Karlsen, Tine Veronica; Liden, Åsa; Leh, Sabine Maria; Ericsson, Madelene; Nilsson, Stefan K.; Reed, Rolf K.; Hultström, Michael. 2019. Time course of decompensation after angiotensin II and high-salt diet in Balb/CJ mice suggests pulmonary hypertension-induced cardiorenal syndrome. American Journal of Physiology. Regulatory Integrative and Comparative Physiology. 316: R563-R570. doi: 10.1152/ajpregu.00373.2018
  • Smeland, Hilde Ytre-Hauge; Lu, Ning; Karlsen, Tine Veronica; Salvesen, Gerd Signe; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug. 2019. Stromal integrin α11-deficiency reduces interstitial fluid pressure and perturbs collagen structure in triple-negative breast xenograft tumors. BMC Cancer. 19: 1-13. doi: 10.1186/s12885-019-5449-z
  • Karlsen, Tine Veronica; Nikpey, Elham; Han, Jianhua; Reikvam, Tore; Rakova, Natalia; Castorena-Gonzalez, Jorge A.; Davis, Michael J.; Titze, Jens M.; Tenstad, Olav; Wiig, Helge. 2018. High-Salt Diet Causes Expansion of the Lymphatic Network and Increased Lymph Flow in Skin and Muscle of Rats. Arteriosclerosis, Thrombosis and Vascular Biology. 38: 2054-2064. doi: 10.1161/ATVBAHA.118.311149
  • Liden, Åsa; Karlsen, Tine Veronica; Guss, Bengt; Reed, Rolf K.; Rubin, Kristofer. 2018. Integrin αVβ3 can substitute for collagen‐binding β1‐integrins in vivo to maintain a homeostatic interstitial fluid pressure. Experimental Physiology. 103: 629-634. doi: 10.1113/EP086902
  • Eigenmann, Miro Julian; Karlsen, Tine Veronica; Krippendorff, Ben-Fillippo; Tenstad, Olav; Fronton, Ludivine; Otteneder, Michael B.; Wiig, Helge. 2017. Interstitial IgG antibody pharmacokinetics assessed by combined in vivo- and physiologically-based pharmacokinetic modelling approaches. Journal of Physiology. 595: 7311-7330. doi: 10.1113/JP274819
  • Karlsen, Tine Veronica; Reikvam, Tore; Tofteberg, Anne; Nikpey, Elham; Skogstrand, Trude; Wagner, Marek; Tenstad, Olav; Wiig, Helge. 2017. Lymphangiogenesis Facilitates Initial Lymph Formation and Enhances the Dendritic Cell Mobilizing Chemokine CCL21 Without Affecting Migration. Arteriosclerosis, Thrombosis and Vascular Biology. 37: 2128-2135. doi: 10.1161/ATVBAHA.117.309883
  • Kopperud, Reidun Kristin; Rygh, Cecilie Brekke; Karlsen, Tine Veronica; Krakstad, Camilla; Kleppe, Rune; Høivik, Erling Andre; Bakke, Marit; Tenstad, Olav; Selheim, Frode; Liden, Åsa; Madsen, Lise; Pavlin, Tina; Taxt, Torfinn; kristiansen, k; Curry, FE; Reed, Rolf K.; Doskeland, Stein Ove. 2017. Increased microvascular permeability in mice lacking Epac1 (Rapgef3). Acta Physiologica. 219: 441-452. doi: 10.1111/apha.12697
  • Kryvi, Harald; Rusten, Iselin; Fjelldal, Per Gunnar; Nordvik, Kari; Totland, Geir Kåre; Karlsen, Tine Veronica; Wiig, Helge; Long, John H. 2017. The notochord in Atlantic salmon (Salmo salar L.) undergoes profound morphological and mechanical changes during development. Journal of Anatomy. 231: 639-654. doi: 10.1111/joa.12679
  • Nikpey Esfahlan, Elham; Karlsen, Tine Veronica; Rakova, Natalia; Titze, Jens M.; Tenstad, Olav; Wiig, Helge. 2017. High-salt diet causes osmotic gradients and hyperosmolality in skin without affecting interstitial fluid and lymph. Hypertension. 69: 660-668. doi: 10.1161/HYPERTENSIONAHA.116.08539
  • Papadakou, Panagiota; Bletsa, Athanasia; Yassin, Mohammed Ahmed Alamin Yousif; Karlsen, Tine Veronica; Wiig, Helge; Berggreen, Ellen. 2017. Role of Hyperplasia of Gingival Lymphatics in Periodontal Inflammation. Journal of Dental Research. 96: 467-476. doi: 10.1177/0022034516681762
  • Steinskog, Eli Sihn Samdal; Sagstad, Solfrid Johanne; Wagner, Marek; Karlsen, Tine Veronica; Yang, Ning; Markhus, Carl Erik Nordvik; Yndestad, Synnøve; Wiig, Helge; Eikesdal, Hans Petter. 2016. Impaired lymphatic function accelerates cancer growth. OncoTarget. 7: 45789-45802. doi: 10.18632/oncotarget.9953
  • Aspelund, Aeksanteri; Antila, Salli; Proulx, Steven; Karlsen, Tine Veronica; Karaman, Sinem; Detmar, Michael; Wiig, Helge; Alitalo, Kari. 2015. A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules. Journal of Experimental Medicine. 212: 991-999. doi: 10.1084/jem.20142290
  • Papadakou, Panagiota; Karlsen, Tine Veronica; Wiig, Helge; Berggreen, Ellen. 2015. Determination of lymph flow in murine oral mucosa using depot clearance of near-infrared-labeled albumin. JIM - Journal of Immunological Methods. 425: 97-101. doi: 10.1016/j.jim.2015.06.014
  • Sagstad, Solfrid Johanne; Oveland, Eystein; Karlsen, Tine Veronica; Haslene-Hox, Hanne; Tenstad, Olav; Wiig, Helge. 2015. Extracellular matrix composition affects rat skin distribution volume of plasma proteins with different size and charge. American Journal of Physiology. Heart and Circulatory Physiology. 308: H29-H38. doi: 10.1152/ajpheart.00545.2014
  • Lu, Ning; Karlsen, Tine Veronica; Reed, Rolf K.; Kusche-Gullberg, Marion; Gullberg, Donald. 2014. Fibroblast α11β1 integrin regulates tensional homeostasis in fibroblast/A549 carcinoma heterospheroids. PLOS ONE. 9. doi: 10.1371/journal.pone.0103173
  • Helle, Frank; Karlsen, Tine Veronica; Tenstad, Olav; Titze, Jens; Wiig, Helge. 2013. High-salt diet increases hormonal sensitivity in skin pre-capillary resistance vessels. Acta Physiologica. 207: 577-581. doi: 10.1111/apha.12049
  • Markhus, Carl Erik Nordvik; Karlsen, Tine Veronica; Wagner, Marek; Svendsen, Øyvind Sverre; Tenstad, Olav; Alitalo, Kari; Wiig, Helge. 2013. Increased interstitial protein because of impaired lymph drainage does not induce fibrosis and inflammation in lymphedema. Arteriosclerosis, Thrombosis and Vascular Biology. 33: 266-274. doi: 10.1161/ATVBAHA.112.300384
  • Rosengren, Bert-Inge; Sagstad, Solfrid Johanne; Karlsen, Tine Veronica; Wiig, Helge. 2013. Isolation of interstitial fluid and demonstration of local proinflammatory cytokine production and increased absorptive gradient in chronic peritoneal dialysis. American Journal of Physiology - Renal, fluid and electrolyte physiology. 304: F198-F206. doi: 10.1152/ajprenal.00293.2012
  • Wiig, Helge; Karlsen, Tine Veronica; Tenstad, Olav; Titze, Jens. 2013. Increased interstitial osmolality in skin of rats on a high salt diet. The FASEB Journal. 27:680.2. 1 pages.
  • Wiig, Helge; Schroeder, Agnes; Neuhofer, Wolfgang; Jantsch, Jonathan; Kopp, Christoph; Karlsen, Tine Veronica; Boschmann, Michael; Goss, Jennifer; Bry, Maija; Rakova, Natalia; Dahlmann, Anke; Brenner, Sven; Tenstad, Olav; Nurmi, Harri; Mervaala, Eero; Wagner, Hubertus; Beck, Franz-Xaver; Mueller, Dominik; Kerjaschki, Dontscho; Luft, Friedrich C; Harrison, David G; Alitalo, Kari; Titze, Jens. 2013. Immune cells control skin lymphatic electrolyte homeostasis and blood pressure. Journal of Clinical Investigation. 123: 2803-2815. doi: 10.1172/JCI60113
  • Karlsen, Tine Veronica; Kopperud, Reidun Kristin; Liden, Åsa; Brekke, Cecilie; Reed, Rolf K.; Doskeland, Stein Ove. 2012. Microvascular permeability in the absence of Epac1 activity. The FASEB Journal. 26. 1 pages.
  • Karlsen, Tine Veronica; McCormack, Emmet Martin; Mujic, Maja; Tenstad, Olav; Wiig, Helge. 2012. Minimally invasive quantification of lymph flow in mice and rats by imaging depot clearance of near-infrared albumin. American Journal of Physiology. Heart and Circulatory Physiology. 302: H391-H401. doi: 10.1152/ajpheart.00842.2011
  • Oveland, Eystein; Karlsen, Tine Veronica; Haslene-Hox, Hanne; Semaeva, Elvira; Janaczyk, Bartlomiej; Tenstad, Olav; Wiig, Helge. 2012. Proteomic Evaluation of Inflammatory Proteins in Rat Spleen Interstitial Fluid and Lymph during LPS-Induced Systemic Inflammation Reveals Increased Levels of ADAMST1. Journal of Proteome Research. 11: 5338-5349. doi: 10.1021/pr3005666
  • Österholm, Cecilia M.; Lu, Ning; Liden, Åsa; Karlsen, Tine Veronica; Gullberg, Donald; Reed, Rolf K.; Kusche-Gullberg, Marion. 2012. Fibroblast EXT1-levels influence tumor cell proliferation and migration in composite spheroids. PLOS ONE. 7. 10 pages. doi: 10.1371/journal.pone.0041334
  • Curry, Fitz-Roy E.; Brekke, Cecilie; Karlsen, Tine Veronica; Wiig, Helge; Adamson, RH; Clark, Joyce F.; Lin, Yueh-Chen; Gassner, Birgit; Thorsen, Frits Alan; Moen, Ingrid; Tenstad, Olav; Kuhn, Michaela; Reed, Rolf K. 2010. Atrial natriuretic peptide modulation of albumin clearance and contrast agent permeability in mouse skeletal muscle and skin: role in regulation of plasma volume. Journal of Physiology. 588: 325-339. doi: 10.1113/jphysiol.2009.180463
  • Curry, FE; Samardizc, H; Lenz, JF; Adamson, RH; Lin, YC; Karlsen, Tine Veronica; Brekke, Cecilie; Reed, Rolf K.; Kuhn, M. 2009. MULTI-LEVEL SYSTEMS APPROACH TO ANP DEPENDENT REGULATION OF VASCULAR PERMEABILITY AND PLASMA VOLUME IN MICE. Journal of Neurophysiology. 59: 58-58.
  • Karlsen, Tine Veronica; Bletsa, Athanasia; Gjerde, Eli-Anne Birgitte; Reed, Rolf Kåre. 2007. Lowering of interstitial fluid pressure after neurogenic inflammation in mouse skin is partly dependent on mast cells. American Journal of Physiology. Heart and Circulatory Physiology. 292: H1821-H1827. doi: 10.1152/ajpheart.00365.2006
  • Karlsen, Tine Veronica; Alitalo, Kari; Karkkainen, Marika J.; Wiig, Helge. 2006. Transcapillary fluid balance consequences of missing initial lymphatics studied in a mouse model of primary lymphoedema. Journal of Physiology. 574: 583-596. doi: 10.1113/jphysiol.2006.108308
  • Karlsen, Tine Veronica; Karkkainen, M; Alitalo, K; Wiig, Helge. 2005. Fluid volume regulation parameters in a mouse model of primary lymphedema. The FASEB Journal. 19.
  • Karlsen, Tine Veronica; Iversen, Vegard Vereide; Forsberg, Erik; Kjellen, Lena; Reed, Rolf Kåre; Gjerde, Eli-Anne Birgitte. 2004. Neurogenic inflammation in mice deficient in heparin-synthesizing enzyme. American Journal of Physiology. Heart and Circulatory Physiology. 286: H884-H888.
  • Nedrebø, Torbjørn; Karlsen, Tine Veronica; Salvesen, Gerd Signe; Reed, Rolf Kåre. 2004. A novel function of insulin in rat dermis. Journal of Physiology. 559.2: 583-591.
  • Gjerde, Eli-Anne Birgitte; Karlsen, Tine Veronica; Reed, Rolf Kåre. 2003. Lowering of interstitial fluid pressure in rat trachea after substance P alone and in combination with calcitonin gene-related peptide. Acta Physiologica Scandinavica. 178: 123-127.
  • Karlsen, Tine V.; Serck-Hanssen, Guldborg. 2002. Acute stimulation by IGF-I of amino acid trtansport system A in chromaffin cells depends on PI3 kinase activation and the electrochemical gradient of Na+. Annals of the New York Academy of Sciences. 971: 573-575.
  • Thomas, T.D.; Berrah, N.; Bozek, J.; Carroll, T.X.; Hahne, J.; Karlsen, Tine Veronica; Kukk, E.; Sæthre, L.J. 1999. Photon Energy Depodence of the 1qu/1qg Intensity Ratio in Carbon 1s Photoelectron spectroscopy of Ethyne. Physical Review Letters. 82: 1120.
Reports and theses
  • Karlsen, Tine Veronica. 2007. New knowledge on edema pathophysiology deriving from animal studies involving increased filtration and reduced lymph drainage.

More information in national current research information system (CRIStin)

Research groups