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Torgils Fossen's picture

Torgils Fossen

Professor
  • E-mailTorgils.Fossen@uib.no
  • Phone+47 55 58 34 63
  • Visitor Address
    Realfagbygget, Allégt. 41
  • Postal Address
    Postboks 7803
    5020 BERGEN
Academic article
  • Show author(s) 2020. Phosphosite analysis of the cytomegaloviral mRNA export factor pUL69 reveals serines with critical importance for recruitment of cellular proteins Pin1 and UAP56/URH49. Journal of Virology. 1-19.
  • Show author(s) 2020. Isolation and Characterization of Larvicidal Phenolic Acids from Kotschya thymodora Leaves. Journal of Applied Sciences and Environmental Management. 1483-1488.
  • Show author(s) 2020. Flavonoids and other phenolics in herbs commonly used in Norwegian commercial kitchens. Food Chemistry. 1-8.
  • Show author(s) 2020. Acylated flavone O-glucuronides from the aerial parts of Nepeta curviflora. Molecules. 3782-3791.
  • Show author(s) 2019. Flavonoids and other phenolics in herbs commonly used in Norwegian commercial kitchens. Food Chemistry.
  • Show author(s) 2019. Cytotoxic saponins and other natural products from flowering tops of Narthecium ossifragum L. Phytochemistry. 67-77.
  • Show author(s) 2019. Bumblebee death associated with Tilia x europaea L. Biochemical Systematics and Ecology. 16-23.
  • Show author(s) 2019. A novel poly-oxygenated flavone glucoside from aerial parts of the Brazilian plant Neoglaziovia variegata (Bromeliaceae). Heliyon. 1-13.
  • Show author(s) 2018. The N-Terminus of the HIV-1 p6 Gag Protein Regulates Susceptibility to Degradation by IDE. Viruses. 1-23.
  • Show author(s) 2017. Synthesis of a novel tripeptidomimetic scaffold and biological evaluation for CXC chemokine receptor 4 (CXCR4) antagonism. Tetrahedron. 3866-3877.
  • Show author(s) 2017. Proteolysis of mature HIV-1 p6 Gag protein by the insulin-degrading enzyme (IDE) regulates virus replication in an Env-dependent manner. PLOS ONE. 1-29.
  • Show author(s) 2017. Non-Polar Natural Products from Bromelia laciniosa, Neoglaziovia variegata and Encholirium spectabile (Bromeliaceae). Molecules.
  • Show author(s) 2017. Influence of chain length on the activity of tripeptidomimetic antagonists for CXC chemokine receptor 4 (CXCR4). Bioorganic & Medicinal Chemistry. 646-657.
  • Show author(s) 2016. Toxic aromatic compounds from fruits of Narthecium ossifragum L. Phytochemistry. 76-85.
  • Show author(s) 2016. The prolyl isomerase pin1 promotes the herpesvirus-induced phosphorylation-dependent disassembly of the nuclear lamina required for nucleocytoplasmic egress. PLoS Pathogens. 30 pages.
  • Show author(s) 2016. New Polyfunctional Phragmalin Limonoids from Neobeguea mahafalensis. Planta Medica. 1087-1095.
  • Show author(s) 2016. Glutamic acid residues in HIV-1 p6 regulate virus budding and membrane association of gag. Viruses.
  • Show author(s) 2015. pUL69 of human cytomegalovirus recruits the cellular protein arginine methyltransferase 6 via a domain that is crucial for mRNA export and efficient viral replication. Journal of Virology. 9601-9615.
  • Show author(s) 2015. The native structure of annexin A2 peptides in hydrophilic environment determines their anti-angiogenic effects. Biochemical Pharmacology. 1-15.
  • Show author(s) 2015. Pseudoaeruginosins, nonribosomal peptides in nodularia spumigena. ACS Chemical Biology. 725-733.
  • Show author(s) 2015. Growing with dinosaurs: natural products from the Cretaceous relict Metasequoia glyptostroboides Hu & Cheng - a molecular reservoir from the ancient world with potential in modern medicine. Phytochemistry Reviews. 35 pages.
  • Show author(s) 2015. First identification of natural products from the African medicinal plant Zamioculcas zamiifolia - A drought resistant survivor through millions of years. Fitoterapia. 280-285.
  • Show author(s) 2014. The first flavonoid isolated from Bromelia laciniosa (Bromeliaceae). Journal of Medicinal Plants Research. 558-563.
  • Show author(s) 2014. Reversible ketomethylene-based inhibitors of human neutrophil proteinase 3. Journal of Medicinal Chemistry. 9396-9408.
  • Show author(s) 2014. Mutation of the highly conserved ser-40 of the HIV-1 p6 gag protein to phe causes the formation of a hydrophobic patch, enhances membrane association, and polyubiquitination of gag. Viruses. 3738-3765.
  • Show author(s) 2014. Design, synthesis, and biological evaluation of scaffold-based tripeptidomimetic antagonists for CXC chemokine receptor 4 (CXCR4). Bioorganic & Medicinal Chemistry. 4759-4769.
  • Show author(s) 2014. Balticidins A-D, antifungal hassallidin-like lipopeptides from the Baltic Sea cyanobacterium Anabaena cylindrica Bio33. Journal of natural products. 1287-1296.
  • Show author(s) 2014. 6-Carboxydihydroresveratrol 3-O-β-glucopyranoside - A novel natural product from the Cretaceous relict Metasequoia glyptostroboides. Fitoterapia. 109-114.
  • Show author(s) 2013. Novel GHB-derived natural products from European mistletoe (Viscum album). Pharmaceutical Biology. 981-986.
  • Show author(s) 2013. Influenza A virus protein PB1-F2 from different strains shows distinct structural signatures. Biochimica et Biophysica Acta - Proteins and Proteomics. 568-582.
  • Show author(s) 2013. HIV-1 p6 - a structured to flexible multifunctional membrane-interacting protein. Biochimica et Biophysica Acta - Biomembranes. 816-823.
  • Show author(s) 2012. Nuclear import of isoforms of the cytomegalovirus kinase pUL97 is mediated by differential activity of NLS1 and NLS2 both acting through classical importin-alpha binding. Journal of General Virology. 1756-1768.
  • Show author(s) 2012. Novel aminoalkaloids from European mistletoe (Viscum album L.). Phytochemistry Letters. 677-681.
  • Show author(s) 2012. HIV-1 p6-Another viral interaction partner to the host cellular protein cyclophilin A. Biochimica et Biophysica Acta - Proteins and Proteomics. 667-678.
  • Show author(s) 2012. A new protolimonoid from Capuronianthus mahafalensis. Fitoterapia. 901-906.
  • Show author(s) 2011. The Host-Pathogen interaction of human cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains. BMC Structural Biology. 16 pages.
  • Show author(s) 2011. Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly. Retrovirology. 16 pages.
  • Show author(s) 2010. The intriguing Cyclophilin A-HIV-1 Vpr interaction: prolyl cis/trans isomerisation catalysis and specific binding. BMC Structural Biology. 15 pages.
  • Show author(s) 2010. Flavone C-Glycosides from seeds of Fenugreek, Trigonella foenum-graecum L. Journal of Agricultural and Food Chemistry. 7211-7217.
  • Show author(s) 2009. Structural properties of anthocyanins: Rearrangement of C-Glycosyl-3-deoxyanthocyanidins in acidic aqueous solutions. Journal of Agricultural and Food Chemistry. 6668-6677.
  • Show author(s) 2009. C-glycosylanthocyanidins synthesized from C-glycosylflavones. Phytochemistry. 278-287.
  • Show author(s) 2008. The flavonoids of tomatoes. Journal of Agricultural and Food Chemistry. 2436-2441.
  • Show author(s) 2008. Synthesis of full length PB1-F2 influenza A virus proteins from 'Spanish flu' and 'bird flu'. Journal of Peptide Science. 954-962.
  • Show author(s) 2007. Structural characterization and oligomerization of PB1-F2, a proapoptotic influenza A virus protein. Journal of Biological Chemistry. 353-363.
  • Show author(s) 2007. Reactivity of anthocyanins and pyranoanthocyanins. Studies on aromatic hydrogen-deuterium exchange reactions in methanol. Journal of Agricultural and Food Chemistry. 8261-8268.
  • Show author(s) 2007. Proline 35 of human immunodeficiency virus type 1 (HIV-1) Vpr regulates the integrity of the N-terminal helix and the incorporation of Vpr into virus particles and supports the replication of R5-tropic HIV-1 in human lymphoid tissue ex vivo. Journal of Virology. 9572-9576.
  • Show author(s) 2007. Onions: A source of unique dietary flavonoids. Journal of Agricultural and Food Chemistry. 10067-10080.
  • Show author(s) 2007. Molar Absorptivities and Reducing Capacity of Pyranoanthocyanins and Other Anthocyanins. Journal of Agricultural and Food Chemistry. 10591-10598.
  • Show author(s) 2007. Covalent anthocyanin-flavone dimer from leaves of Oxalis triangularis. Phytochemistry. 552-562.
  • Show author(s) 2007. Anthocyanin 3-galactosides from Cornus alba 'Sibirica' with glucosidation of the B-ring. Phytochemistry. 640-645.
  • Show author(s) 2006. Preparative isolation and NMR characterization of carboxypyranoanthocyanins. Journal of Agricultural and Food Chemistry. 3572 -3577.
  • Show author(s) 2006. Characterization of Hemiacetal Forms of Anthocyanidin 3-O-b-Glycopyranosides. Journal of Agricultural and Food Chemistry. 9340-9346.
  • Show author(s) 2005. Solution structure of the human immunodeficiency virus type 1 p6 protein. Journal of Biological Chemistry. 42515-42527.
  • Show author(s) 2005. Isolation and identification of flavonoids, including flavone rotamers, from the herbal drug Crataegi folium cum flore (hawthorn). Phytochemical Analysis. 334-341.
  • Show author(s) 2005. Flavone C-glycosides from leaves of Oxalis triangularis. Journal of Agricultural and Food Chemistry. 10057-10060.
  • Show author(s) 2005. Acylated anthocyanins from leaves of Oxalis triangularis. Phytochemistry. 1133-1140.
  • Show author(s) 2004. Dimeric anthocyanins from strawberry (Fragaria ananassa) consisting of pelargonidin 3-glucoside covalently linked to four flavan-3-ols. Phytochemistry. 1421-1428.
  • Show author(s) 2004. Anthocyanin from strawberry (Fragaria ananassa) with the novel aglycone, 5-carboxypyranopelargonidin. Phytochemistry. 405-410.
  • Show author(s) 2003. Structural characterization of the HIV-1 Vpr N terminus - Evidence of cis/trans-proline isomerism. Journal of Biological Chemistry. 43188-43201.
  • Show author(s) 2003. Anthocyanins with 4'-glucosidation from red onion, Allium cepa. Phytochemistry. 1367-1374.
  • Show author(s) 2003. Anthocyanins from red onion, Allium cepa, with novel aglycon. Phytochemistry. 1217-1220.
  • Show author(s) 2003. Anthocyanins from flowers of the orchids Dracula chimaera and D. cordobae. Phytochemistry. 783-787.
  • Show author(s) 2003. Anthocyanins from a Norwegian potato cultivar. Food Chemistry. 433-437.
  • Show author(s) 2002. Anthocyanins of grasses. Biochemical Systematics and Ecology. 855-864.
  • Show author(s) 2001. Cyanidin 3-(6"-acetylgalactoside) and other anthocyanins from reddish leaves of the water lily, Nymphaea alba. Journal of Horticultural Science & Biotechnology. 213-215.
  • Show author(s) 2001. Anthocyanins from maize, Zea mays, and reed canarygrass, Phalaris arundinacea. Journal of Agricultural and Food Chemistry. 2318-2321.
  • Show author(s) 2000. Covalent anthocyanin-flavonol complexes from flowers of chive, Allium schoenoprasum. Phytochemistry. 317-323.
  • Show author(s) 2000. Colour and stability of the six common anthocyanidin 3-glucosides in aqueous solutions. Food Chemistry. 101-107.
  • Show author(s) 2000. Anthocyanins from tubers and shoots of the purple potato. Journal of Horticultural Science & Biotechnology. 360-363.
  • Show author(s) 1999. Flavonoids from blue flowers of Nymphaea caerulea. Phytochemistry. 1133-1137.
  • Show author(s) 1999. Delphinidin 3'-galloylgalactosides from blue flowers of Nymphaea caerulea. Phytochemistry. 1185-1188.
  • Show author(s) 1999. Cyanidin 3-(2'',3''-digalloylglucoside) from red leaves of Acer platanoides. Phytochemistry. 1697-1700.
  • Show author(s) 1999. Anthocyanin pigments of tulips. Phytochemistry. 1687-1692.
  • Show author(s) 1998. Petunidin 3-O-a-rhamnopyranoside-5-O-b-glucopyranoside and other anthocyanins from flowers of Vicia villosa. Journal of Agricultural and Food Chemistry. 4568-4570.
  • Show author(s) 1998. Myricetin 3-rhamnopyranosyl (1-6) galactoside from Nymphaea x marliacea. Phytochemistry. 1997-2000.
  • Show author(s) 1998. Flavonoids from red onion (Allium cepa). Phytochemistry. 281-285.
  • Show author(s) 1998. Cyanidin 3-(6"-succinyl-b-glucopyranoside) and other anthocyanins from Phragmites australis. Phytochemistry. 1065-1068.
  • Show author(s) 1998. Color and stability of pure anthocyanins influenced by pH including the alkaline region. Food Chemistry. 435-440.
  • Show author(s) 1998. Anthocyanins from flowers and leaves of Nympaea x marliacea cultivars. Phytochemistry. 823-827.
  • Show author(s) 1997. Malonylated anthocyanins of garilc Allium sativum. Food Chemistry. 215-217.
  • Show author(s) 1997. Acylated anthocyanins from leaves of the water lily, Nympaea x marliacea. Phytochemistry. 353-357.
  • Show author(s) 1996. Unusual substitution pattern of anthocyanins containing aliphatic acids. Polyphenols Communications. 11-12.
  • Show author(s) 1996. Characteristic Anthocyanin Pattern from Onions and other Allium spp. Journal of Food Science. 703-706.
  • Show author(s) 1996. Characteristic Anthocyanin Pattern from Onions and other Allium spp. Journal of Food Science. 703-706.
  • Show author(s) 1995. Anthocyanins with unusual acylation pattern from stem of Allium victorialis. Phytochemistry. 1809-1812.
Report
  • Show author(s) 2017. Assessment of the potential connection between Tilia trees and bumblebee Death. Opinion of the Panel on Alien organisms and trade in endangered species (CITES) of the Norwegian Scientific Committee for Food Safety. 2017:15. 2017:15. .
Lecture
  • Show author(s) 2020. 100 år siden spanskesyken.
  • Show author(s) 2020. 100 år siden Spanskesyken –Den glemte katastrofen: Norsk og internasjonalt helsevesens største utfordring noensinne.
  • Show author(s) 2016. The Nobel Prize in Medicine 2015.
  • Show author(s) 2013. PB1-F2 –Structural signatures of highly pathogenic influenza viruses.
Popular scientific lecture
  • Show author(s) 2016. Planter er medisin. Dialogbasert omvisning med kjemikeren, legen og botanikeren om både tradisjonelle og nye medisinplanter.
  • Show author(s) 2000. Farger i naturen.
Academic lecture
  • Show author(s) 2018. Nytt potensielt virkestoff fra urgammel iransk medisinplante.
  • Show author(s) 2017. Rome –en unik kilde til nye antileukemi naturprodukter.
  • Show author(s) 2016. Alpha-helix 2 of the multifunctional regulatory protein pUL69 mediates Pin1-interaction and its phosphorylation is required for efficient multiplication of human cytomegalovirus.
  • Show author(s) 2015. Mutations of viral proteins –and their structural consequences.
  • Show author(s) 2015. Characterization of increasingly complex bioactive natural products.
  • Show author(s) 2012. Two NLS sequences within the cytomegaloviral protein kinase pUL97 regulate the nuclear import of both isoforms through the classical importin α/β pathway.
  • Show author(s) 2012. The intriguing host–pathogen interaction of human cyclophilin A and HIV-1 Vpr: prolyl cis/trans isomerisation catalysis and specific binding.
  • Show author(s) 2012. The Host-Pathogen interaction of Human Cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains.
  • Show author(s) 2012. Recent advances in structural investigations of viral proteins.
  • Show author(s) 2011. The intriguing Host-Pathogen interaction of Human Cyclophilin A and HIV-1 Vpr.
  • Show author(s) 2008. Hydrogen-deuterium exchange rates of various anthocyanin classes as basis for reactivity studies.
  • Show author(s) 2007. Biological functionality of anthocyanins expressed through structure details.
  • Show author(s) 2007. Analysis of Flavonoids in bulbs of Allium cepa.
  • Show author(s) 2006. Solution structure of the Human Immunodeficiency Virus type 1 p6 protein.
  • Show author(s) 2006. Characterization of novel flavonoids from leaves of Oxalis triangularis including equilibrium forms of a covalent anthocyanin-flavone C-glycoside.
  • Show author(s) 2006. Characterization of novel flavonoid classes by NMR spectroscopy.
  • Show author(s) 2005. The anthocyanins: A review on occurence, chemistry and properties during the last decade.
  • Show author(s) 2005. Structure of the multifunctional HIV-1 protein p6.
  • Show author(s) 2003. Structure and interaction studies of HIV-1 proteins. Multidimensional NMR of 15N-labelled full-length Vpr.
  • Show author(s) 1999. Stability of anthocyanins in alkaline media. 1st. International Congress on Pigments in Food Technology.
  • Show author(s) 1998. Colour and stability of pure anthocyanins in aqueous solutions at high pH values.
  • Show author(s) 1996. Antocyaner i løkplanter.
  • Show author(s) 1996. Anthocyanins with unusual acylation pattern from Allium species.
Masters thesis
  • Show author(s) 2019. Antileukemia activity of plant natural products and hemisynthetic analogs.
  • Show author(s) 2017. Effekt av utvalgte unike naturstoffer på celleviabilitet og sårtilheling i nevroendokrine PC12 celler med særlig fokus på Annexin A2.
Popular scientific article
  • Show author(s) 1998. Flavonoidar i planter - Forsvar og kommunikasjon. Naturen.
  • Show author(s) 1998. Antocyaner i mat. Kjemi. 14-16.
Doctoral dissertation
  • Show author(s) 2017. Characterization of bioactive natural products from edible, medicinal and toxic plants.
  • Show author(s) 2007. Isolation, identification and properties of pyranoanthocyanins and anthocyanin forms.
  • Show author(s) 1998. Chemical studies of acylated anthocyanins and other flavonoids isolated from plants. -.
Academic chapter/article/Conference paper
  • Show author(s) 2006. Spectroscopic Techniques Applied to Flavonoids. 76 pages.
  • Show author(s) 2000. Beskrivelse av den trolig eldste norske påskeliljekultivar, basert på kjemiske, morfologiske og cytologiske undersøkelser. 4 pages.
Encyclopedia article
  • Show author(s) 2003. Characterization of anthocyanins by NMR. 1-24. In:
    • Show author(s) 2003. Current Protocols in Food Analytical Chemistry.
Poster
  • Show author(s) 2017. Zamioculcas zamiifolia –an ancient African medicinal plant with undeserved bad reputation?
  • Show author(s) 2017. The secondalpha-helix within pUL69 contains pUL97-phosphorylation sites that critically affect Pin1-mediated isomerization and efficient multiplication of HCMV.
  • Show author(s) 2017. Novel complex polyfunctional phragmalin limonoids from the Madagascar medicinal plant Neobeguea mahafalensis.
  • Show author(s) 2017. Non-polar natural products from the drought resistant Brazilian medicinal plants Bromelia laciniosa, Neoglaziovia variegata and Encholirium spectabile (Bromeliaceae).
  • Show author(s) 2017. Balticidins A−D, Structurally complex antifungal Lipopeptides from the Baltic Sea Cyanobacterium Anabaena cylindrica Bio33.
  • Show author(s) 2016. Peptidyl-prolyl isomerase Pin1 is an important effector in the phosphorylation-triggered reorganization of the nuclear lamina during herpesvirus nuclear egress.
  • Show author(s) 2016. Glutamic acid residues in HIV-1 p6 regulate virus budding and membrane association of gag.
  • Show author(s) 2015. Motifs in HIV-1 p6 Gag that regulate ubiquitination and membrane association of Gag.
  • Show author(s) 2015. Cellular isomerase Pin1 promotes the phosphorylation-triggered disassembly of the nuclear lamina during nuclear egress of alpha-, beta- and gamma-herpesviruses.
  • Show author(s) 2014. Phosphorylation-triggered reorganization of the nuclear lamina during nuclear egress of herpesviruses.
  • Show author(s) 2013. A novel natural product from the dinosaur-age tree Metasequoia glyptostroboides.
  • Show author(s) 2012. The intriguing host–pathogen interaction of human cyclophilin A and HIV-1 Vpr.
  • Show author(s) 2012. Specification of the HCMV pUL97 isoforms: differences in subcellular localization and functionality.
  • Show author(s) 2012. Serine-40 in HIV-1 p6 regulates Gag ubiquitinylation in an L-domain independent manner.
  • Show author(s) 2012. Novel aminoalkaloids from European Mistletoe.
  • Show author(s) 2011. The Intriguing Cyclophilin A-HIV-1 Vpr Interaction: Prolyl cis/trans Isomerisation Catalysis and Specific Binding.
  • Show author(s) 2008. Reactivity studies by NMR on anthocyanins occurring in fruits and berries.
  • Show author(s) 2007. The impact of anthocyanin purity in antioxidant measurements.
  • Show author(s) 2007. Structural characterization and oligomerization of PB1-F2, a proapoptotic influenza A virus protein.
  • Show author(s) 2007. Proline 35 of HIV-1 Vpr regulates incorporation in virus particles and is required for replication in macrophages.
  • Show author(s) 2007. Analysis of anti-p6 antibodies in HIV-1 infected individuals.
  • Show author(s) 2006. Structure, folding, and oligomerization of PB1-F2, a pro-apoptotic inluenza A virus protein.
  • Show author(s) 2006. Solution structure of the Human Immunodeficiency Virus type 1 p6 protein.
  • Show author(s) 2006. NMR characterization of various forms of anthocyanin 3-glucosides in deuterated methanolic solutions with and without acid.
  • Show author(s) 2006. Characterization of 5-carboxypyranoanthocyanins.
  • Show author(s) 2006. Anthocyanin 3-galactosides with glucosyl moieties on the B-ring from Cornus alba ‘Sibirica’.
  • Show author(s) 2005. Nutritional aspects of anthocyanin pigments.
  • Show author(s) 2005. Flavonoids from the herbal drug “Crataegi folium cum flore”, hawthorn.
  • Show author(s) 2004. Covalently linked anthocyanin-flavanol dimers.
  • Show author(s) 2004. Characterization of Pyranoanthocyanins.
  • Show author(s) 2001. Chive, a specialised flavonoid producer.
  • Show author(s) 2000. Anthocyanins from grasses.
  • Show author(s) 1999. Analysis of covalent anthocyaninflavonol complexes from flowers of chives Allium schoenoprasum.
  • Show author(s) 1997. Anthocyasins of some bluish flowers (<EM>Lupinus, Echium</EM> and <EM>Echium</EM> and <EM>Vicia</EM> spp).
Academic literature review
  • Show author(s) 2007. Onions: A source of unique dietary flavonoids. Journal of Agricultural and Food Chemistry. 10067-10080.

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