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Night shift work is associated with sleep problems and multiple other negative health effects. Prolonged wakefulness induces deficits in brain functions, which affects alertness, performance and mood. My PhD-project is a translational project and involves simulating night-shift work in both rats and humans. I aim to investigate how night-shift work affects waking function and cognitive performance during work, and subsequent sleep. I will also investigate how different light interventions during simulated night-shifts will affect the brains' processing capasity and how it may impact daytime sleep.
- 2020. Role of nocturnal light intensity on adaptation to three consecutive night shifts: a counterbalanced crossover study. Occupational and Environmental Medicine.
- 2018. Mathematical modeling of sleep state dynamics in a rodent model of shift work. Neurobiology of Sleep and Circadian Rhythms. 37-51.
- 2017. No escaping the rat race: simulated night shift work alters the time-of-day variation in BMAL1 translational activity in the prefrontal cortex. Frontiers in Neural Circuits. 1-12.
- 2016. Shift in food intake and changes in metabolic regulation and gene expression during simulated night-shiftwork: A rat model. Nutrients. 1-13.
- 2016. A rodent model of night-shift work induces short-term and enduring sleep and electroencephalographic disturbances. Journal of Biological Rhythms. 48-63.
- 2019. Effects of Different Light Intensities on Adaptation to Simulated Night Shifts: A Randomized Counterbalanced Crossover Study.
- 2018. Nattarbeid og den trøtte hjernen- kan lys hjelpe? SØVN. 30-33.
- 2018. NRK Hordaland Morgensending- Hvordan få sove i sommervarmen?
- 2018. Prolonged photoperiod alters time in sleep and slow-wave activity. The impact of blue-enriched light.
- 2018. Extending the photoperiod impacts circadian rhythmicity and gene expression in prefrontal cortex and retina- Impact of exposure to blue-enriched light. .
- 2018. Extended photoperiod alters sleep and expression of synaptic plasticity-associated genes. The impact of blue-enriched light.
- 2018. Extended photoperiod alters circadian rhythmicity and expression of neuroplasticity markers. The impact of blue-enriched light.
- 2018. Effects of bright light on sleepiness and cognitive performance during simulated night shift work.
- 2018. Daytime sleep following night shifts- impact of light intensity.
- 2018. Daytime sleep following bright light exposure during simulated night shift work.
- 2018. Bright light exposure during simulated night shift work- impact on daytime sleep.
Mathematical modeling of sleep state dynamics in a rodent model of shift work. Rempe MJ, Grønli J, Pedersen TT, Mrdalj J, Marti AR, Meerlo P, Wisor JP. (2018). Neurobiology of Sleep and Circadian Rhythms 5:37-51
No Escaping the Rat Race: Simulated Night Shift Work Alters the Time-of-Day Variation in BMAL1 Translational Activity in the Prefrontal Cortex. Marti AR, Patil S, Mrdalj J, Meerlo P, Skrede S, Pallesen S, Pedersen TT, Bramham CR, Grønli J. Frontiers in Neural Circuits, 2017 11(70). doi: 10.3389/fncir.2017.00070.
A rodent model of night-shift work induces short-term and enduring sleep and electroencephalographic disturbances. Grønli J, Meerlo P, Pedersen TT, Pallesen S, Skrede S, Marti AR, Wisor JP, Murison R, Henriksen TEG, Rempe MJ, Mrdalj J. J Biol Rhythm, 2017 Feb;32(1):48-63. doi: 10.1177/0748730416675460.
Shift in food intake and changes in metabolic regulation and gene expression during simulated night-shift work. A rat model. Marti AR, Meerlo P, Grønli J, van Hasselt SJ, Mrdalj J, Pallesen S, Pedersen TT, Henriksen TEG, Skrede S.Nutrients, 2016 Nov 8;8(11). doi:10.3390/nu8110712
2017-> : PhD-candidate, Department of Biological and Medical Psychology, University of Bergen
2015-2017: Lecturer, VID Specialized University, Bergen
2013-2015: MSc, human physiology, Department of Biomedicine, University of Bergen