- E-mailUna.Solvik@uib.no
- Phone+47 55 58 67 27+47 938 69 427
- Visitor AddressAlrek health cluster, Årstadveien 17Block A, 3rd floor5009 Bergen
- Postal AddressPostboks 78045020 Bergen
Affiliated with the research groups SMIL og Arbeid, Helse og Kjønn
My main research interests:
- Laboratorymedisin
- Diabetes
- Coagulation - INR
- Self control anticoagulant treatment
- Analytical quality control
- Women's health
Associated with Section for Health Sciences and Teaching group leader for Master's in Health and Society
Associated with master in Health and Society and Masters in Health Science.
Member of the group for teaching group leaders, Department of Global Public Health and Primary Care
Associated with Program committee for Master's in health sciences, IGS, UiB
Course coordinator Quantitative research methods, 5 ECTS (HELSAM303) and Quantitative research methods and traditions, 10 ECTS (HELSAM305)
Coordinator for Masters in Health Science, radiographer and biomedical laboratory scientists
- (2023). Intensified follow-up of patients with type 1 diabetes and poor glycaemic control: A multicentre quality improvement collaborative based on data from the Norwegian Diabetes Register for Adults. BMJ Open Quality. 11 pages.
- (2023). Aggregated data from the same laboratories participating in two glucose external quality assessment schemes show that commutability and transfers of values to control materials are decisive for the biases found. Clinical Chemistry and Laboratory Medicine.
- (2021). Type 2-diabetes i fastlegepraksis – en fokusgruppestudie. Tidsskrift for Den norske legeforening. 1-9.
- (2020). Pharmacists’ experience of a diabetes risk-assessment service and analytical quality control in community pharmacies – A focus-group study. Research in Social and Administrative Pharmacy. 1259-1266.
- (2020). Performance and user-friendliness of the rapid antigen detection tests QuickVue Dipstick Strep A test and DIAQUICK Strep A Blue Dipstick for pharyngotonsillitis caused by Streptococcus pyogenes in primary health care. European Journal of Clinical Microbiology and Infectious Diseases. 549-558.
- (2019). Quality of warfarin therapy and quality of life are improved by self-management for two years. Thrombosis and Haemostasis. 1632-1641.
- (2019). Commutability of a whole-blood external quality assessment material for point-of-care C-reactive protein, glucose, and hemoglobin testing. Clinical Chemistry. 791-797.
- (2018). The EuBIVAS: Within- and between-subject biological variation data for electrolytes, lipids, urea, uric acid, total protein, total bilirubin, direct bilirubin, and glucose. Clinical Chemistry. 1380-1393.
- (2018). Risk assessment and HbA1c measurement in Norwegian community pharmacies to identify people with undiagnosed type 2 diabetes ? A feasibility study. PLOS ONE. 1-13.
- (2018). Quality control of Norwegian pharmacy HbA1c testing: a modest beginning. Journal of Diabetes Science and Technology. 753-761.
- (2017). The EuBIVAS project: within- and between-subject biological variation data for serum creatinine using enzymatic and alkaline picrate methods and implications for monitoring. Clinical Chemistry. 1527-1536.
- (2017). Intensive educational efforts combined with external quality assessment improve the preanalytical phase in general practitioner offices and nursing homes. Clinical Chemistry and Laboratory Medicine. 1857-1864.
- (2017). Biological variation estimates obtained from 91 healthy study participants for 9 enzymes in serum. Clinical Chemistry. 1141-1150.
- (2016). The potential for deprescribing in care home residents with Type 2 diabetes. International Journal of Clinical Pharmacy. 977-984.
- (2016). Sample collections from healthy volunteers for biological variation estimates' update: A new project undertaken by the Working Group on Biological Variation established by the European Federation of Clinical Chemistry and Laboratory Medicine. Clinical Chemistry and Laboratory Medicine. 1599-1608.
- (2016). 'I try not to bother the residents too much' - the use of capillary blood glucose measurements in nursing homes. BMC Nursing.
- (2015). Egenkontroll av warfarinbehandling. Tidsskrift for Den norske legeforening. 849-853.
- (2014). The influence of coagulation factors on the in-treatment biological variation of international normalized ratio for patients on warfarin. Scandinavian Journal of Clinical and Laboratory Investigation. 470-476.
- (2014). Nursing home patients with diabetes: Prevalence, drug treatment and glycemic control. Diabetes Research and Clinical Practice. 102-109.
- (2013). External quality assessment of point-of-care methods: model for combined assessment of method bias and single-participant performance by the use of native patient samples and noncommutable control materials. Clinical Chemistry. 363-371.
- (2013). Diagnosing Diabetes Mellitus: Performance of Hemoglobin A(1c) Point-of-Care Instruments in General Practice Offices. Clinical Chemistry. 1790-1801.
- (2012). Effect of coagulation factors on discrepancies in International Normalized Ratio results between instruments. Clinical Chemistry and Laboratory Medicine. 1611-1620.
- (2010). Discrepancies in International Normalized Ratio Results between Instruments: A Model to Split the Variation into Subcomponents. Clinical Chemistry. 1618-1626.
- (2009). Internal quality control of prothrombin time in primary care: comparing the use of patient split samples with lyophilised control materials. Thrombosis and Haemostasis. 593-600.
- (2009). Internal quality control of prothrombin time in primary care: comparing the use of patient split samples with lyophilised control materials. Thrombosis and Haemostasis. 593-600.
- (2006). External quality assessment of prothrombin time: the split-sample model compared with external quality assessment with commercial control material. Scandinavian Journal of Clinical and Laboratory Investigation. 337-350.
- (2006). External quality assessment of prothrombin time: The split-sample model compared with external quality assessment with commercial control material. Scandinavian Journal of Clinical and Laboratory Investigation. 337-349.
- (1994). The effect of serum amyloid protein A fragment-SAA25-76 on blood platelet aggregation. Thrombosis Research. 299-305.
- (1994). Modulation of thrombotic responses in moderately stenosed arteries by cigarette smoking and aspirin ingestion. Arteriosclerosis and thrombosis. 617-621.
- (2007). Response to Kitchen et al.'s external quality assessment of prothrombin time: The split-sample model compared to external quality assessment with commercial control material. Scandinavian Journal of Clinical and Laboratory Investigation. 676-677.
- (2013). Rolleutvidelse ved noen bildediagnostiske avdelinger i Norge.
- (2013). PGMI klassifisering av mammografibilder ved interne og eksterne mamma-radiografer.
- (2013). Er laboratorierutiner og laboratoriekvalitet ved norske sykehjem endret? Har opplæring og oppfølging initiert av Noklus som del av Omsorgsplan 2015 nyttet?
- (2012). Sammenligning av nukleinsyre isoleringsteknikker i forbindelse med etablering av qPCR påvisningsmetode for Borrelia infeksjon.
- (2011). Videreutdanning i Ultralyd for radiografer I hvilken grad er læringsmålene nådd? En kontrollert prospektiv sammenlignende studie 6 mnd etter endt utdanning.
- (2011). Trygg antikoagulasjonsbehandling: Pasienter i Norge kan drive egenkontroll av warfarinbehandling.
- (2011). Tredimensjonale ultralyd volummålinger IN VITRO validering av metode til oppfølging av abdominale aortaaneurismer.
- (2011). Strålebehandling til kvinner med brystkreft Endring av venstre ventrikkels ejeksjonsfraksjon (LVEF) gjennom et behandlingsforløp med strålebehandling, målt med den nukleærmedisinske metoden planar MUGA- scan.
- (2011). Bildeveiledet stråleterapiVil bruk av konvensjonell stimulator bidra til å minimere systematiske innstillingsavvik, og dermed øke innstillingspresisjonen, sammenlignet med bildeveiledet innstilling på behandlingsapparat?
- (2010). Utfordringer ved digital bildeteknologi; en kvalitativ studie av radiografers rolle og deres oppfatning av bildekvalitet ved arbeid med digitale røntgenbilder.
- (2010). Hvordan lav og høy temperatur påvirker måling av blodsukker med apparater i bruk av personer med diabetes.
- (2010). Feltstyrke ved Magnetisk Resonansskanning af håndled og fingrenes led hos pasienter med leddegigt.
- (2010). Deteksjon av tidlige veggforandringer i halsarterier hos barn og unge med type-1 diabetes.
- (2010). Betydning av pasientleie for tynntarmsdose ved strålebehandling av pasienter med rectumcancer.
- (2010). Betydning av behandlingsleie for reproduserbarhet ved strålebehandling av rectumcancer.
- (2009). Strålebehandling av pasienter med brystkreft og bruk av intensitetsmodulert radioterapi (IMRT).
- (2009). Processerings optimering med Canons software -et fantom projekt om dosis besparelse ved anvendelse af Canons nye DR Spectra software på børnefemur undersøgelser.
- (2007). Analyse av protrombintid i primærhelsetjenesten - vurdering av analysekvalitet og en evaluering av to kontrollsystem for analytisk kvalitetskontroll ved hjelp av datasimuleringer.
- (2018). Hemolysis interference studies: Freeze method should be used in the preparation of hemolyzed samples. Clinical Chemistry and Laboratory Medicine. 1-3.
- (2017). Effect of dabigatran treatment at therapeutic levels on point-of-care international normalized ratio (INR). Clinical Chemistry and Laboratory Medicine. e143-e145.
- (2015). Performance of 10 systems for self-monitoring of blood glucose by trained healthcare professionals and in the hands of the users. Clinical Chemistry. 772-774.
- (2019). Diabetes in care homes. Special emphasis on medicines and blood glucose measurements.
- (2005). External quality assessments of whole blood prothrombin time: Comparison of two methods. Clinica Chimica Acta.
- (2016). ‘It’s a jungle out there’ - A focus group study about being diagnosed with type 2 diabetes.
- (2016). A feasibility study for risk assessment ofType 2 Diabetes (T2D) in pharmacies.
More information in national current research information system (CRIStin)
Risøy AJ, Kjome R, Sandberg S, Sølvik UØ. Diabetes risk assessments and HbA1c-measurements in community pharmacies. Int J Pharm Pract In Press
Gidske G, Sandberg S, Fauskanger P, Pelanti J, Tollånes MC, Solsvik AE, Sølvik UØ, Vie WS, and Stavelin A. Aggregated data from the same laboratories participating in two glucose external quality assessment schemes show that commutability and transfers of values to control materials are decisive for the biases found. Clin Chem Lab Med In Press
Madsen TV, Cooper JG, Carlsen S, Løvaas K, Rekdal M, Igland J, Sandberg S, Ueland GÅ, Iversen MM, Sølvik UØ. Intensified follow-up of patients with type 1 diabetes and poor glycaemic control.A multi-centre quality improvement collaborative based on data from the Norwegian Diabetes Register for Adults. BMJ Open Quality 2023;12:e002099.
Hare L, Hetlevik A, Yogarajan R, Kjome RLS, Sølvik UØ. Type 2-diabetes i fastlegepraksis – en fokusgruppestudie. Tidsskr Nor Legeforen 2021. doi: 10.4045/tidsskr.20.0623.
Risøy AJ, Kjome, RLS, Svensberg K, Råheim M, Sølvik UØ. Pharmacists’ experience of a diabetes risk-assessment service and analytical quality control in community pharmacies: a focus-group study. Research in Social and Administrative Pharmacy 2020. Pharmacists’ experience of a diabetes risk-assessment service and analytical quality control in community pharmacies – A focus-group study - ScienceDirect
Sølvik UØ, Boija EE, Ekvall S, Jabbour A, Breivik AC Nordin G, Sandberg S. Performance and user-friendliness of the rapid antigen detection tests QuickVue Dipstick Strep A test and DIAQUICK Strep A Blue Dipstick for pharyngotonsillitis caused by Streptococcus pyogenes in primary health care. European Journal of Clinical Microbiology and Infectious Diseases 2020 s. 1-10
Kjome RL, Pettersen MS, Råheim M, Sølvik UØ. Being diagnosed with type 2 diabetes – shock, shame and information chaos. A focus group study among persons with type 2 diabetes in Norway.
Sølvik UØ, Løkkebø E, Kristoffersen AH, Brodin E, Averina M, Sandberg S. Quality of warfarin therapy and quality of life are improved by self-management for two years. Thrombosis and Haemostasis 2019;65:791-797. https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0039-1693703.
Bukve T, Sandberg S, Wenche SV, Sølvik U, Christensen NG, Stavelin A. Commutability of a whole-blood external quality assurance material for point-of-care C-reactive protein, glucose, and hemoglobin testing. Clin Chem 2019;65:6 http://clinchem.aaccjnls.org/content/clinchem/early/2019/03/06/clinchem.2018.300202.full.pdf
Aarsand AK, Diaz-Garzon J, Fernandez-Calle P, Guerra E, Locatelli M, Bartlett WA, Sandberg S, Røraas T, Ceriotti F,Sølvik UO, Sylte MS, Coskun A, Serteser M, Unsal I, Tosato F, Plebani M, Jonker N, Barla G and Carobene A. The EuBIVAS: Within- and between-subject biological variation data for electrolytes, lipids, urea, uric acid, total protein, total bilirubin, direct bilirubin and glucose. Clin Chem 2018;64:9.
Gidske G, Sølvik UØ, Kristensen GB, Sandberg S. Hemolysis interference studies: Freeze Method should be used in the preparation of hemolyzed samples. Clin Chem Lab Med. 2018; 56:e220–e222.
Sølvik UØ, Risøy AJ, Kjome R, Sandberg S. Quality control of Norwegian Pharmacy HbA1c testing: A modest beginning. J Diab Sci Technol. 2018;12:753–761. http://journals.sagepub.com/eprint/43MUKZ66cs8kvrKKFs2E/full
Risøy AJ, Kjome RLS, Sandberg S, Sølvik UØ.Risk assessment and HbA1c measurement in Norwegian community pharmacies to identify people with undiagnosed type 2 diabetes - a feasibility study. PLOS ONE. 2018;13: e0191316. https://doi.org/10.1371/journal.pone.0191316.
Carobene A, Marino I, Coskun A, Serteser M, Unsal I, Guerra E, Bartlett WA, Sandberg S, Aarsand AK, Sylte MS, Røraas T, Sølvik UO, Fernandez-Calle P, Diaz-Garzon J, Tosato F, Plebani M, Jonker N, Barla G and Ceriotti F on behalf of the European Biological Variation Study of the EFLM Working Group on Biological Variation. The EuBIVAS Project: Within–and Between-Subject Biological Variation Data for Serum Creatinine Using Enzymatic and Alkaline Picrate Methods and Implications for Monitoring. Clin Chem. 2017;63. http://clinchem.aaccjnls.org/content/early/2017/07/12/clinchem.2017.275115
Sølvik UØ, Bjelkarøy WI, van den Berg K, Saga AL, Helle B. Hager HB and Sandberg S. Intensive educational efforts combined with external quality assessment improve the pre-analytical phase in general practitioner offices and nursing homes. Clin Chem Lab Med. 2017;55:1857-1864. DOI 10.1515/cclm-2016-115
Carobene A, Røraas T, Sølvik UO, Sylte MS, Sandberg S, Guerra E, Marino I, Jonker N, Barla G, Bartlett WA, Fernandez-Calle P, Garzon JG, Tosato F, Plebani M, Coskun A, Serteser M, Unsal I, and Ceriotti F. Biological variation estimates obtained from 91 healthy subjects for nine enzymes in serum. On behalf of the European Biological Variation Study (EuBIVAS) of the EFLM working-group on biological variation. Clin Chem 2017;63:1141-1150.
Løkkebø EL, Kristoffersen AH, Stavelin A, Sølvik UØ. Effect of dabigatran treatment at therapeutic levels on Point-of-Care International Normalized Ratio. Clin Chem Lab Med 2016. DOI 10.1515/cclm-2016-0872.
Carobene A, Strollo M, Jonker N, Barla G, Bartlett WA, Sandberg S, Sylte MS, Røraas T, Sølvik UØ, Fernandez-Calle P, Díaz-Garzón J, Tosato F, Plebani M, Coşkun A, Serteser M, Unsal I, Ceriotti F. Sample collections from healthy volunteers for biological variation estimates´ update: a new project undertaken by the Working Group on Biological Variation established by the European Federation of Clinical Chemistry and Laboratory Medicine. Clin Chem Lab Med 2016. DOI 10.1515/cclm-2016-0035.
Andreassen LM, Kjome RL, Sølvik UØ, HoughtonJ, Desborough JA. The potential for deprescribing in care home residents with Type 2 diabetes. Int J Clin Pharm 2016;38:977-84.
Sølvik UØ, Risa M, JacobsenC, MonsenG, Sandberg S. Performance of ten systems for self-monitoring of blood glucose by trained healthcare professionals and in the hands of the users. Clin Chem 2015;61:772-4.
Sølvik UØ, Løkkebø ES, Kristoffersen AH, Stavelin A, Binder S, Sandberg S. Self-management of warfarin therapy. Tidsskr Nor Legeforening 2015;135:849-53.
Andreassen LM, Kjome RL, Kristensen G, Sølvik UØ, Sandberg S. Nursing home patients with diabetes: Prevalence, drug treatment and glycemic control. Diabetes Res Clin Pr 2014;105:102-9.
Sølvik UØ, Røraas TH, Petersen PH, Stavelin AV, Monsen G, Sandberg S. The influence of coagulation factors on the in-treatment biological variation of international normalized ratio for patients on warfarin. Scand J Clin Lab Invest 2014;74:470-6.
Sølvik UØ, Røraas T, Christensen NG, Sandberg S. Diagnosing Diabetes Mellitus: Performance of Hemoglobin A1c Point-of-Care Instruments in General Practice Offices. Clin Chem 2013;59:1790-801.
Stavelin A, Petersen PH, Sølvik UØ, Sandberg S. External Quality Assessment of Point-of-Care Methods: Model For Combined Assessment of Method Bias and Single-Participant Performance by the Use of Native Patient Samples and Noncommutable Control Materials. Clin Chem 2013;59:363-71.
Sølvik UØ, Røraas TH, Petersen PH, Stavelin AV, Monsen G, Sandberg S. Effect of coagulation factors on discrepancies in International Normalized Ratio results between instruments. Clin Chem Lab Med 2012;50:1611-20.
Sølvik UØ, Petersen PH, Monsen G, Stavelin AV, Sandberg S. Discrepancies in international normalized ratio results between instruments: a model to split the variation into subcomponents. Clin Chem 2010;56:1618-26.
Stavelin A, Petersen PH, Sølvik U, Sandberg S. Internal quality control of prothrombin time in primary care: comparing the use of patient split samples with lyophilised control materials. Thromb Haemost 2009;102:593-600.
Sølvik UØ, Stavelin A, Christensen NG, Sandberg S. External quality assessment of prothrombin time: the split-sample model compared with external quality assessment with commercial control material. Scand J Clin Lab Invest 2006;66:337-49.
Orning L, Fischer PM, Hu CK, Agner E, Engebretsen M, Husbyn M, Petersen LB, Ørvim U, Llinas M, Sakariassen KS. A cyclic pentapeptide derived from the second EGF-like domain of Factor VII is an inhibitor of tissue factor dependent coagulation and thrombus formation. Thromb Haemost 2002;87:13-21.
Sølvik UØ, Haraldsen G, Fiane AE, Boretti E, Lambris JD, Fung M, Thorsby E, Mollnes TE. Human serum-induced expression of E-selectin on porcine aortic endothelial cells in vitro is totally complement mediated. Transplantation 2001;72:1967-73.
Saethre M, Sølvik UØ, Haraldsen G, Fiane AE, Boretti E, Thorsby E, Platt JL, Mollnes TE. Human serum-induced porcine endothelial cell E-selectin expression is associated with IgG3 and IgM anti-Gal antibodies. Xenotransplantation 2002;9:350-8.
Sølvik UØ, Haraldsen G, Fiane AE, Boretti E, Lambris JD, Fung M, Thorsby E, Mollnes TE. Human serum-induced expression of E-selectin on porcine aortic endothelial cells in vitro is totally complement mediated. Transplantation 2001;72:1967-73.
Sølvik UO, Haraldsen G, Fiane AE, Boretti E, Thorsby E, Mollnes TE. C1-inhibitor attenuates human serum induced E-selectin expression of pig aortic endothelial cells. Transplant Proc 2001;33:789-90.
Hagberg IA, Sølvik UØ, Opdahl H, Roald HE, Lyberg T. Inhalation of nitric oxide inhibits ADP-induced platelet aggregation and alpha-granule release. Platelets 1999;10:382-90.
Sakariassen KS, Holme PA, Ørvim U, Barstad RM, Solum NO, Brosstad FR. Shear-induced platelet activation and platelet microparticle formation in native human blood. Thromb Res 1998;92(6 Suppl 2):S33-41.
Ørvim U, Barstad RM, Orning L, Petersen LB, Ezban M, Hedner U, Sakariassen KS.
Antithrombotic efficacy of inactivated active site recombinant factor VIIa is shear dependent in human blood. Arterioscler Thromb Vasc Biol 1997;17:3049-56.
Holme PA, Ørvim U, Hamers MJ, Solum NO, Brosstad FR, Barstad RM, Sakariassen KS. Shear-induced platelet activation and platelet microparticle formation at blood flow conditions as in arteries with a severe stenosis. Arterioscler Thromb Vasc Biol 1997;17:646-53.
Barstad RM, Buchmann MS, Hamers MJ, Orning L, Ørvim U, Stormorken H, Sakariassen KS. Effects of ionic and nonionic contrast media on endothelium and on arterial thrombus formation. Acta Radiol 1996;37:954-61.
Ørvim U, Barstad RM, Stormorken H, Brosstad F, Sakariassen KS. Immunologic quantification of fibrin deposition in thrombi formed in flowing native human blood. Br J Haematol 1996;95:389-98.
Barstad RM, Ørvim U, Hamers MJ, Tjønnfjord GE, Brosstad FR, Sakariassen KS.
Reduced effect of aspirin on thrombus formation at high shear and disturbed laminar blood flow. Thromb Haemost 1996;75:827-32.
Ørvim U, Barstad RM, Vlasuk GP, Sakariassen KS. Effect of selective factor Xa inhibition on arterial thrombus formation triggered by tissue factor/factor VIIa or collagen in an ex vivo model of shear-dependent human thrombogenesis. Arterioscler Thromb Vasc Biol 1995;15:2188-94.
Ørvim U, Roald HE, Stephens RW, Roos N, Sakariassen KS. Tissue factor-induced coagulation triggers platelet thrombus formation as efficiently as fibrillar collagen at arterial blood flow conditions. Arterioscler Thromb 1994;14:1976-83.
Syversen PV, Saeter U, Cunha-Ribeiro L, Ørvim U, Sletten K, Husby G, Sakariassen KS. The effect of serum amyloid protein A fragment-SAA25-76 on blood platelet aggregation. Thromb Res 1994;76:299-305.
Roald HE, Ørvim U, Bakken IJ, Barstad RM, Kierulf P, Sakariassen KS. Modulation of thrombotic responses in moderately stenosed arteries by cigarette smoking and aspirin ingestion. Arterioscler Thromb 1994;14:617-21.
Diagnose pattern and health-care trajectories among women in the menopausal transition
Women’s experience with menopause in the context of midlife and in encounters with health care
Quality of treatment of type 1 diabetes in the specialist health service
Factors associated with chronic kidney disease among patients with diabetes mellitus in Norway
Experiences with self-management of anticoagulant treatment in Norway