Broegelmann Research Laboratory
Our overarching objective is to improve the quality of life for patients suffering from chronic inflammatory diseases. Also, we aim to consolidate and strengthen our international recognition for the identification, development and promotion of new approaches for diagnosis and treatment of autoimmune and inflammatory diseases.
The laboratory was initiated in 1957 after a donation to the University of Bergen and is co-localized and integrated with the Department of Clinical Science (Klinisk Institutt 2). Internationally the unit is one of the leading groups on experimental, clinical and genetic studies of Sjögren's syndrome. The group and BRL are closely associated with theScandinavian Journal of Immunology and the Bergen Research School in Inflammation.
Current major fields of research are :
- Translational studies in autoimmunity (exocrine glands, joints, skin); autoantibodies and biomarkers
- Functional genomics and genetic basis of the autoimmune exocrinopathy (human/murine)
- Dendritic cells in immunotherapy
- Host-microbe interactions (P.gingivalis - arthritis)
- Cardiovascular disease
The core financial support comes from the Broegelmann Foundation. Other major funding agencies are/have been the EU (ten contracts, five as coordinator), The Western Norway Regional Health Care (Helse Vest), The Research Council of Norway ("miljøstøtte" and GLOBVAC), the Foundation Health and Rehabilitation, the Cancer Foundation and Bergen Forskningsstiftelse. "Between 1962 and 2018, BRL has contributed to the finalization of more than 80 PhD/doctoral degrees and more than 15 Masters degrees. BRL has been the organizer of three international immunology meetings in Bergen 1997, 2001 and 2002, and the International Symposium on Sjögren’s Syndrome in 2015. Since 1999 the unit has been the main editorial office for the Scandinavian Journal of Immunology with Prof R. Jonsson as Editor-in-Chief 1999 - 2017.
Western Norway Regional Health Care (Helse Vest)
Bergen Research Foundation (Bergens forskningsstiftelse)
We thank the contributors for their financial support!
HUIMM901 Project Seminars in Immunology (14:30, seminar room 5th floor, Laboratory building)
HUIMM902 Journal Club & Watch (12:00, seminar room 5th floor, Laboratory building)
Dag Yihairuo PhD fellow
"The tumour microenvironment of the upper and lower gastrointestinal tract differentially influences dendritic cell maturation