Fish immunology

From 2000-2010

Main content

Melingen, G.O. & Wergeland, H.I. 2000. Serum protein and IgM profiles in connection with the smolting and vaccination of out-of- season Atlantic salmon (Salmo salar L.) Aquaculture, 188: 189-201.

Pettersen, E.F., Bjerknes, R. & Wergeland, H.I. 2000. Studies of Atlantic salmon (Salmo salar L.) blood, spleen and head kidney leukocytes using specific monoclonal abtibodies in immunohistochemistry and flow cytometry. Fish & Shellfish Immunology, 10: 695-710.

Torkildsen, L., Samuelsen, O.B., Lunestad, B.T. and Bergh, Ø. 2000. Minimum inhibitory concentrations of chloramphenicol, florfenicol, trimethoprim/sulfadiazine and flumequine in seawater of bacteria associated with scallops (Pecten maximus) larvae. Aquaculture 185:1-12

Andersen, S., Burnell, G. and Bergh, Ø. 2000. Flow-through systems for culturing great scallop larvae. Aquaculture International, 8:249-257.

Mortensen, S., van der Meeren, T., Fosshagen, A., Hernar, I., Harkestad, L., Torkildsen, L. and Bergh, Ø. 2000. Mortality of scallop spat in cultivation, infested with tube dwelling bristle worms, Polydora sp. Aquaculture International 8:267-271.

Samuelsen, O.B., Húsgarđ, S., Torkildsen, L. and Bergh, Ø. 2000. The efficacy of a single intraperitoneal injection of flumequine in the treatment of a bacterial infection in corkwing wrasse (Symphodus melops). Journal of Aquatic Animal Health 12:324-327.

Steine, N.O., Melingen, G.O. & Wergeland, H.I. 2001. Antibodies against Vibrio salmonicida lipopolysaccharide (LPS) and whole bacteria in sera from Atlantic salmon (Salmo salar L.) vaccinated during the smolting and early post smolt period. Fish & Shellfish Immunology, 11: 39-52.

Wergeland, H.I. & Jakobsen R.A. 2001. A salmonid cell line (TO) for production of infectious salmon anaemia virus (ISAV). Diseases of Aquatic Organisms, 44: 183-190.

Imsland, B.K., Jonassen, T.M., Langston, A., Hoare, R., Wergeland, H.I., FitzGerald, R., Mulcahy, M., & Stefansson. S.O. 2001. The interrelation of growth performance and disease resistance of juvenile Atlantic halibut (Hippoglossus hippoglossus L.) from different populations. Aquaculture, 204:167-177.

Langston, A.L., Hoare, R., Stefánsson, M., Fitzgerald, R. & Wergeland, H.I. & Mulcahy, M. 2001. The effect of temperature on non-specific defence parameters of three strains of juvenile Atlantic halibut (Hippoglossus hippoglossus L.). Fish & Shellfish Immunology, 12: 61-76.

Bergh, Ø. , Vikanes, L., Makridis, P., Skjermo, J., Knappskog, D.H. and Rødseth, O.M. 2001. Uptake and processing of a Vibrio anguillarum bacterin in Artemia franciscana measured by ELISA and immunohistochemistry. Fish and Shellfish Immunology 11(1):15-22.

Bergh, Ø., Nilsen, F. and Samuelsen, O.B. 2001. Diseases, prophylaxis and treatment of the Atlantic halibut, Hippoglossus hippoglossus: a review. Diseases of Aquatic Organisms 48:57-74.

Makridis, P. , Bergh, Ø, Skjermo, J. and Vadstein O. 2001. Addition of bacteria bioencapsulated in Artemia metanauplii to a rearing system for halibut larvae Aquaculture International 9(3):225-235.

Bergh, Ø. and Strand, Ø. 2001. Great Scallop, Pecten maximus, research and culture strategies in Norway: a review. Aquaculture International, 9:305-318.

Hoare, R., Langston, A.L., Hovland, H., Imsland, A., Stefansson, S., Mulchay, M. & Wergeland, H.I. 2002. Susceptibility of three different stocks of juvenile Atlantic halibut (Hippoglossus hippoglossus L.) cultured at two different temperatures to Vibrio anguillarum and temperature effect on antibody response. Fish & Shellfish Immunology 13: 111-123.

Melingen, G.O. & Wergeland, H.I. 2002. Physiological effects of an oil-adjuvanted vaccine on out-of-season Atlantic salmon (Salmo salar L.) smolt. Aquaculture 214: 397-409.

Melingen, G.O., Pettersen, E.F. & Wergeland, H.I. 2002. Leucocyte populations and responses to immunization and photoperiod manipulation in Atlantic salmon (Salmo salar L.)  0+ smolt Aquaculture 214: 381-396.

Bowden, TJ, Menoyo-Luque, D, Bricknell IR & Wergeland, H. 2002.Efficacy of different administration routes for vaccination against Vibrio anguillarum in Atlantic halibut (Hippoglossus hippoglossus L). Fish & Shellfish Immunology. 12: 283-285.

Jensen, S., Bergh, Ø., Enger, Ø., and Hjeltnes, B. 2002.Use of PCR-RFLP of 16S rRNA genes to characterise bacteria cultured from halibut fry. Canadian Journal of Microbiology, Vol 48(5):379-386.

Samuelsen, O.B, Ervik, A., Torkildsen, L, and Bergh, Ø. 2002. The efficacy of a single intraperitoneal injection of flumequine or oxytetracycline hydrochloride to prevent outbreak of atypical Aeromonas salmonicida infection in goldsinny wrasse Ctenolabrus rupestris L. following stress. Aquaculture International 10:257-264.

Torkildsen, L., Coyne, R., Samuelsen, O.B., Magnesen, T., and Bergh, Ø. 2002. Treatment of early life stages of scallop (Pecten maximus) with antimicrobial agents; searching for an alternative to chloramphenicol. Aquaculture International 1:399-409.

Pettersen, E,F., Ulvenes, M, Melingen, G.O. & Wergeland H.I. 2003. Pheriheral blood and head kidney leucocyte populations during out-of.season (0+) parr-smolt transformation and seawater transfer of atlantic salmon (Ssalmo salarL.) Fish & Shellfish Immunology. 15:375-385.

Jensen, S., Samuelsen, O.B., Andersen, K., Torkildsen, L., Lambert, C., Choquet, G., Paillard, C., and Bergh, Ø. 2003. Characterization of strains of Vibrio splendidus and Vibrio tapetis isolated from corkwing wrasse (Symphodus melops) suffering vibriosis. Diseases of Aquatic Organisms 53(1):25-31.

Sandaa, R.A., Magnesen, T., Torkildsen, L., and Bergh, Ø. 2003. Characterisation of bacterial communities associated with early life stages of cultured great scallop (Pecten maximus), using denaturing gradient gel electrophoresis (DGGE) Systematic and Applied Microbiology, 26, 302-311.

Samuelsen, O.B., Kvenseth, P.G., Andreassen J., Torkildsen, L., Ervik, A., and Bergh, Ø. 2003. The efficacy of a single intraperitoneal injection of oxolinic acid in the treatment of bacterial infections in goldsinny wrasse (Ctenolabrus rupestris) and corkwing wrasse (Symphodus melops) studied under field and laboratory conditions. Journal of Veterinary Pharmacology and Therapeutics, 26(3) 181-186

Samuelsen, O.B., Bergh, Ø., and Ervik, A. 2003. A single-dose pharmacokinetic study of oxolinic acid and vetoquinol, an oxolinic acid ester, in cod, Gadus morhua L., held in seawater at 8ºC and in vitro antibacterial activity of oxolinic acid against Vibrio anguillarum strains isolated from diseased cod. Journal of Fish Diseases, 26:339-347.

Samuelsen, O.B., Bergh, Ø., and Ervik, A. 2003. Pharmacokinetics of florfenicol in cod, Gadus morhua L., held in seawater at 8ºC and in vitro antibacterial activity against Vibrio anguillarum. Diseases of Aquatic Organisms 56:127-133

Coyne, R., Bergh, Ø., and Samuelsen, O.B. 2004. Determination of oxytetracycline in fish muscle by liquid chromatography. Journal of Chromatography B, 810(2): 325-328, 2004.

Coyne, R., Bergh, Ø., Samuelsen, O., Andersen, K., Lunestad, B.T., Nilsen, H., Dalsgaard, I., and Smith, P. 2004. Attempt to validate breakpoint MIC values estimated from pharmacokinetic data obtained during oxolinic acid therapy of winter ulcer disease in Atlantic salmon (Salmo salar). Aquaculture 238:51-66

Coyne, R., Hjeltnes, B., Bergh, Ø., Andersen, K., Rudra, H. and Smith, P. 2004. Quantitative properties of data generated by the examination of Aeromonas salmonicida infected fish by the standard bacteriological loop. Aquaculture 236:27-35.

Coyne, R., Samuelsen, O., Bergh, Ø., Andersen, K., Pursell, L., Dalsgaard, I., and Smith, P. 2004. On the validity of setting breakpoint minimum inhibition concentrations at one quarter of the plasma concentration achieved following oral administration of oxytetracycline. Aquaculture 239:23-35.

Coyne, C. Samuelsen, O.B., Kongshaug, H., Andersen, K. Dalsgaard, I., Peter Smith, P.and Bergh, Ø. 2004. A comparison of oxolinic acid concentrations in farmed and laboratory held rainbow trout (Oncorhynchus mykiss) following oral therapy Aquaculture 239:1-13.

Hjelm, M., Bergh, Ø., Riaza, A., Nielsen, J., Melchiorsen, J., Jensen, S., Duncan, H., Ahrens, P., Birkbeck, H., and Gram, L. 2004. Selection and identification of autochthonous probiotic bacteria from turbot larvae (Scophthalmus maximus) rearing units. Systematic and Applied Microbiology, 27:360-371.

Jensen, S., Øvreås, L., Bergh, Ø., Torsvik, V. 2004. Phylogenetic analysis of bacterial communities associated with larvae of the Atlantic halibut propose succession from a uniform normal flora. Systematic and Applied Microbiology, 27:728-736.

NicGabhainn, S., Amedeo, M., Bergh, Ø., Dixon, B., Donachie, L.,Carson, J., Coyne, R., Curtin, J., Dalsgaard, I., Maxwell G., and Smith, P. 2004. The precision and robustness of published protocols for disc diffusion assays of antimicrobial agent susceptibility: an inter-laboratory study. Aquaculture, 240:1-18.

Samuelsen, O.B., and Bergh, Ø. 2004. Efficacy of orally administered florfenicol and oxolinic acid for the treatment of vibriosis in cod (Gadus morhua) Aquaculture 235: 27-35.

Skjermo, J. and Bergh Ø. 2004. High-M alginate immunostimulation of Atlantic halibut (Hippoglossus hippoglossus L.) larvae using Artemia for delivery, increases resistance against vibriosis. Aquaculture 238:107-113.

Rønneseth, A., Pettersen, E.F. & Wergeland, H.I. 2005. Leucocytes of anadromous and landlocked strains of Atlantic salmon (Salmo salar L.) in the smolting period. Fish & Shellfish Immunology. 19: 229-239.

Pettersen, E.F., Bjørløw, I., Hagland, T.J. & Wergeland, H.I. 2005

Effect of seawater temperature on leucocyte populations in Atlantic salmon post-smolts. Veterinary Immunology and Immunopathology.106: 65-76.

Coyne, R., Bergh, Ø., Smith, P., and Samuelsen, O.B. 2005. A question of temperature related differences in plasma oxolinic acid concentrations achieved in rainbow trout (Oncorhynchus mykiss) under laboratory conditions following commercial farm dosing regime. Aquaculture 245:13-17.

Torkildsen, L., Lambert, C., Nylund, A., Magnesen, T., and Bergh, Ø. 2005. Bacteria associated with early life stages of the great scallop, Pecten maximus: impact on larval survival. Aquaculture International 13:575-592

Vik-Mo F.T., Bergh, Ø., and Samuelsen O.B. 2005. Efficacy of orally administered flumequine in the treatment of vibriosis caused by Listonella anguillarum in Atlantic cod Gadus morhua. Diseases of Aquatic Organisms 67:87-92.

Glover, K., Bergh, Ø., Rudra, H., and Skaala Ø. 2005. Juvenile growth and susceptibility to Aeromonas salmonicida subsp. salmonicida in Atlantic salmon (Salmo salar L.) of farmed, hybrid, and wild parentage. Aquaculture, 254:72-81.

Rønneseth,A., Pettersen, E.F. & Wergeland, H.I .2006 Neutrophils and B-cells in blood and head kidney of Atlantic salmon (Salmo salar L.) challenged with infectious pancreatic necrosis virus (IPNV). 20:610-620.

Ingerslev, H-C., Cunningham, C. & Wergeland, H.I. 2006. Cloning and expression of TNF-α, IL-1 and COX-2 in an anadromous and landlocked strain of Atlantic salmon (Salmo salar L.) during the smolting period. Fish and Shellfish Immunology 20: 450-461.

Ingerslev, H-C, Pettersen, E.F., Jakobsen, R.A, Bie, P.C. & Wergeland, H.I. 2006.

Expresion profiling and validation of reference gene candidates in immune relevant tissues and cells from Atlantic salmon (Salmo salar L.) Molecular Immunology 43:1194-1201.

Planas, M., Perez-Lorenzo, M., Hjelm, M. Gram, L., Fiksdal, I.U., Bergh, Ø., and Pintado, J. 2006. Probiotic effect in vivo of Roseobacter strain 27-4 against Vibrio (Listonella) anguillarum infections in turbot (Scophthalmus maximus L.) larvae. Aquaculture 255:323-333

Sandlund, N., Torkildsen L., Magnesen, T. Mortensen, S. and Bergh, Ø. 2006. Immunohistochemistry of Great Scallop, Pecten maximus larvae experimentally challenged with pathogenic bacteria. Diseases of Aquatic Organisms 69:163-173.

Korsnes, K., Nicolaisen, O., Skår, C.K., Nerland, A.H., and Bergh, Ø. 2006. Bacteria in the gut of juvenile cod Gadus morhua fed live feed enriched with four different commercial diets. ICES Journal of Marine Science, 63:296-301.

Coyne, R., Smith, P., Dalsgaard, I., Nilsen, H., Kongshaug H., Bergh, Ø., Samuelsen O. 2006. Winter ulcer disease of post-smolt Atlantic salmon:an unsuitable case for treatment? Aquaculture 253:171-178

Magnesen, T., Bergh, Ø. and Christophersen, G. 2006. Scallop larval yields in a commercial flow-through rearing system with continuous feeding. Aquaculture International, in press. 14(4):377-394.

Mortensen, S., Korsnes, K., Bergh, Ø. 2006. "Eyes wide shut" - A critical view of aquaculture health management and risk factors in the "real world". Bulletin of the European Association of Fish Pathologists 26(1):1-5.

Samuelsen, O.B., Nerland, A., Svåsand, T., Jørgensen, T., Schrøder M., and Bergh, Ø., 2006. Viral and bacterial diseases of Atlantic cod Gadus morhua, their prophylaxis and treatment: a review. Diseases of Aquatic Organisms, 71:239-254.

Seljestokken, B. Bergh, Ø., Melingen, G.O., Rudra, H. Olsen, R.H., Samuelsen, O.B. 2006.Treating experimentally induced vibriosis (Listonella anguillarum) in cod (Gadus morhua) with florfenicol. Journal of Fish Diseases, 2, 737-742.

Samuelse, O.B. 2006. Absorbtion, tissue distribution, metabolism and excretion of ormethoprim and sulphadimethoxine in cod (Gadus morhua) after oral administration of Romet. Journal of Applied Ichtyology, 22:68-71.

Samuelse, O.B. 2006. Pharmacokinetics of quinolones in fish. A review. Aquaculture, 255:55-75.

Samuelse, O.B. 2006. Multiple dose pharmacokinetic study of oxolinic acid in cod, Gadus morhua L. Aquaculture International, 14:443-450.

Rønneseth, A.,  Wergeland, H.I. & Pettersen, E.F. 2007 Neutrophils and B-cells in Atlantic cod (Gadus morhua L.). Fish & Shellfish Immunology , 23: 493-503.

Rønneseth,A, Wergeland.H.I ,Devik,M, Evensen,Ø. & Pettersen, E.F. 2007 Mortality after IPNV challenge of Atlantic salmon (Salmo salar L.) differs based on developmental stage of fish or challenge route. Aquaculture 271 :100–111.

Bergh, Ø. and Samuelsen, O.B. 2007. Susceptibility of Atlantic salmon smolt (Salmo salar) corkwing wrasse (Symphodus melops) and goldsinny wrasse (Ctenolabrus rupestis) to experimental challenge with two Vibrio spp. isolated from corkwing wrasse suffering from vibriosis. Aquaculture International 15:11-18.

Bergh, Ø. 2007. The dual myths of the healthy wild fish and the unhealthy farmed fish. Diseases of Aquatic Organisms, 75:169-164.

Brunvold, L., Sandaa, R.A., Bleie, H., Mikkelsen, H., Welde, E., and Bergh Ø. 2007. Characterisation of bacterial communities associated with intensively rared cod (Gadus morhua) larvae using Denaturing Gradient Gel Electrophoresis (DGGE). Aquaculture, 272: 319-327.

Patel, S., Korsnes K, Bergh, Ø., Vik-Mo F, Pedersen J, Nerland A.H. 2007. Nodavirus in farmed Atlantic cod Gadus morhua in Norway. Diseases of Aquatic Organisms 77:169-173.

Pettersen,EF, Ingerslev, H-C, Stavang, V, Egenberg, M & Wergeland, HI .2008

A highly phagocytic cell line TO from Atlantic salmon is CD83 positive and M-CSFR negative, indicating a dendritic-like cell type. Fish and Shellfish Immunology 25: 809–819.

Sandaa, R.-A., Brunvold. L., Magnesen T., and Bergh Ø. 2008. Monitoring the opportunistic bacteria Pseudoalteromonas sp. LT-13 in a great scallop, Pecten maximus hatcher y. Aquaculture 276:14-21

Ottem KF, Nylund A, Isaksen TE, Karlsbakk E, Bergh Ø. 2008. Occurence of Francisella piscicida in farmed and wild Atlantic cod, Gadus morhua L. in Norway. Journal of Fish Diseases, 31 (7):525-534.

Engelsen AR, Sandlund N, Fiksdal IU, Bergh Ø. 2008. Immunohistochemistry of Atlantic cod larvae Gadus morhua experimentally infected with Vibrio anguillarum. Diseases of Aquatic Organisms, 80:13-20

Paillard, C., Korsnes, K., LeChevallier, P., Leboulay, C. Harkestad, L., Eriksen A.G., Willassen E., , Bergh, Ø., Bovo, C., Skår C., Mortensen, S. 2008. Vibrio tapetis-like strain isolated from introduced Manila clams Ruditapes philippinarum, showing symptoms of Brown Ring Disease in Norway. Diseases of Aquatic Organisms, 81:153-161

Sandlund N, Bergh Ø 2008. Screening and characterisation of potentially pathogenic bacteria associated with Atlantic cod Gadus morhua larvae: Bath challenge trials using a multidish system. Diseases of Aquatic Organisms, 81:203-217

Skilbrei,O., Glover, K., Lunestad, B.T. and Samuelsen, O.B. 2008. A laboratory study to evaluate the use of emamectin benzoate in the control of sea lice in sea-ranched Atlantic salmon (Salmo salar L.). Aquacultur, 285:2-7.

Olsvik, P.-A., Lie, K.K., Mykkeltvedt, E., Samuelsen, O.B., Petersen, K., Stavrum, A.-K., Lunestad, B.T. 2008. Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.). BMC Pharmacology 8:16

Ingerslev H-C., Rønneseth , A., Pettersen E F.& Wergeland,H.I. Differential expression of immune genes in Atlantic salmon (Salmo salar L.) infected intraperitoneally or by cohabitation with IPNV. 2009: Scandinavian Journal of Immunology. 60:90-98.

Mikalsen J., Olsen A.B., Rudra H., Moldal T., Lund T., Djønne B., Bergh Ø., Colquhoun D.J. 2009. , Virulence and pathogenicity of Francisella philomiragia subsp. noatunensis for Atlantic cod (Gadus morhua) and laboratory mice. Journal of Fish Diseases, 32:377-381.

Patel S, Sørhus E, Fiksdal IU, Espedal PG, Bergh Ø, Rødseth OM, Morton HC, Nerland AH. 2009. Ontogeny of lymphoid organs and development of IgM bearing cells in Atlantic halibut (Hippoglossus hippoglossus L.). Fish and Shellfish Immunology, 26: 385-395.

Sandlund N, Rødseth O.M., Knappskog D.H., Fiksdal I.U., Bergh Ø. 2009. Comparative susceptibility of turbot, halibut and cod yolk-sac larvae to challenge with Vibrio spp. Submitted to Diseases of Aquatic Organisms.

Kiessling, A., Johansson, D., Zahl, I.H., Samuelsen, O.B. 2009. Pharmacokinetics, plasma cortisol and effectiveness of benzocaine, MS-222 and isoeugenol measured in individual dorsal aorta cannulated Atlantic salmon (Salmo salar) following bath administration. Aquaculture 286:301-308.

Øverland, S.H., Pettersen, E.F. ,Rønneseth, A. & Wergeland, H.I. 2010. Phagocytosis by B-cells and neutrophilic granulocytes in Atlantic salmon (Salmo salar L.) and Atlantic cod (Gadus morhua L). Fish & Shellfish Immunology 28 :193-204.

Zahl, I.H., Kiessling, A., Samuelsen, O.B., Hansen, M.K. Anaesthesia of Atlantic cod (Gadus morhua) – effect of pre-sedation , and importance of body weight, temperature and acute stress. Aquaculture (In press)

Zahl, I.H., Kiessling, A., Samuelsen, O.B., Hansen, M.K. Anaesthesia of Atlantic halibut (Hippoglossus hippoglossus) – effect of pre-sedation , and importance of body weight and water temperature. Aquaculture (In press)

Zahl, I.H., Kiessling, A., Samuelsen, O.B., Olsen, R.E. Anaesthesia induces stress in Atlantic salmon (Salmo salar), Atlantic cod (Gadus morhua) and Atlantic halibut (Hippoglossus hippoglossus). Fish Physiology and Biochemistry (In press)

Samuelsen, O.B. A single-dose pharmacokinetic study of emamectine benzoate in cod (Gadus morhua) held in sea water at 9ºC. Journal of Fish Diseases (In press)

Glover, K.A., Samuelsen, O.B., Skilbrei, O.T., Boxaspen, K., Lunestad, B.T. Pharmacokinetics of emamectine benzoate administered to Atlantic salmon (Salmo salar L.) by intra-peritoneal injection. Journal of Fish Diseases (In press)

Dhanasiri, A.K.S., Brunvold L., Brinchmann M, Korsnes K, Bergh Ø, Viswanath, K. Observations on the intestinal microflora of wild Atlantic cod Gadus morhua L. upon captive rearing. Submitted to Microbial Ecology

Brunvold, L, Jacobsen, A, Sandaa, R-A, Bergh, Ø, Magnesen, T. Increased survival of great scallop (Pecten maximus) larvae adding probiotic bacteria to algal cultures. Submitted to Aquaculture


Book chapters:

Vadstein, O., Mo, T.A. and Bergh, Ø. 2004.  Microbial interactions, prophylaxis and diseases.  In: Moksness, E., Kjørsvik, E. and Olsen, Y. (eds.) Culture of cold-water marine fish.  Blackwell Scientific publications Ltd., U.K. pp. 28-72.

Bergh, Ø. 2004. Helsesituasjonen for kveite i naturen og i oppdrett. I: Mangor-Jensen, A., og Holm, J.C. (red.) Håndbok i kveiteoppdrett. Havforskningsinstituttet. ISBN 82-7461 –060-1, s. 101-109.

Bergh Ø., Samuelsen, O.B. og Korsnes K. 2005. Sykdommer hos torsk, forebygging og behandling. I: Otterå, H., Taranger, G.L., and Borthen J. (ed.) Oppdrett av torsk – næring med framtid. Pp. 177-182.

Bergh Ø. 2008. Bacterial diseases of fish. Pp. 239-278 in: Eiras J, Segner H, Wahli T and Kapoor B (editors) Fish Diseases. Science Publishers Inc New Hampshire USA.

Bergh Ø., Nerland AH. 2008. Improving disease immunity to reduce antibiotic use in farmed fish. In Lie Ø. (ed) Improving farmed fish quality and safety. Pp. 183-198. Woodhead publishing, Cambridge UK.