2021

Simultaneous Quantification of Aromatase Inhibitors and Estrogens in Postmenopausal Breast Cancer Patients. Bertelsen BE, Viste K, Helland T, Hagland M, Søiland H, Geisler J, Hoel Lende T, Lønning PE, Sagen JV, Mellgren G, Almås B. J Clin Endocrinol Metab. 2021 Dec 27:dgab923. doi: 10.1210/clinem/dgab923. PMID: 34958096

Impact of overweight on glucose homeostasis in MODY2 and MODY3. Romuld IB, Kalleklev TL, Molnes J, Juliusson PB, Njølstad PR, Sagen JV. Diabet Med. 2021 Oct;38(10):e14649. doi: 10.1111/dme.14649. Epub 2021 Aug 5.PMID: 34269485

O-GlcNAcylated p53 in the liver modulates hepatic glucose production. Gonzalez-Rellan MJ, Fondevila MF, Fernandez U, Rodríguez A, Varela-Rey M, Veyrat-Durebex C, Seoane S, Bernardo G, Lopitz-Otsoa F, Fernández-Ramos D, Bilbao J, Iglesias C, Novoa E, Ameneiro C, Senra A, Beiroa D, Cuñarro J, Dp Chantada-Vazquez M, Garcia-Vence M, Bravo SB, Da Silva Lima N, Porteiro B, Carneiro C, Vidal A, Tovar S, Müller TD, Ferno J, Guallar D, Fidalgo M, Sabio G, Herzig S, Yang WH, Cho JW, Martinez-Chantar ML, Perez-Fernandez R, López M, Dieguez C, Mato JM, Millet O, Coppari R, Woodhoo A, Fruhbeck G, Nogueiras R. Nat Commun. 2021 Aug 20;12(1):5068. doi: 10.1038/s41467-021-25390-0.PMID: 34417460 

Genetic Deficiency of TRAF5 Promotes Adipose Tissue Inflammation and Aggravates Diet-Induced Obesity in Mice. Gissler MC, Anto-Michel N, Pennig J, Scherrer P, Li X, Marchini T, Pfeiffer K, Härdtner C, Abogunloko T, Mwinyella T, Sol Mitre L, Spiga L, Koentges C, Smolka C, von Elverfeldt D, Hoppe N, Stachon P, Dufner B, Heidt T, Piepenburg S, Hilgendorf I, Bjune JI, Dankel SN, Mellgren G, Seifert G, Eisenhardt SU, Bugger H, von Zur Muhlen C, Bode C, Zirlik A, Wolf D, Willecke F.Arterioscler Thromb Vasc Biol. 2021 Oct;41(10):2563-2574. doi: 10.1161/ATVBAHA.121.316677. Epub 2021 Aug 5. PMID: 34348490

Hepatic Energy Metabolism Underlying Differential Lipidomic Responses to High-Carbohydrate and High-Fat Diets in Male Wistar Rats. Dankel SN, Bjørndal B, Lindquist C, Grinna ML, Rossmann CR, Bohov P, Nygård O, Hallström S, Strand E, Berge RK. J Nutr. 2021 Jun 16: nxab178. doi: 10.1093/jn/nxab178. PMID: 34132338

Effect of Genetic Variability in 20 Pharmacogenes on Concentrations of Tamoxifen and Its Metabolites. Chen Y, Marcath LA, Eliassen FM, Lende TH, Soiland H, Mellgren G, Helland T, Hertz DL. J Pers Med. 2021 Jun 4;11(6):507. doi: 10.3390/jpm11060507. PMID: 34199712 

Activity-Based Anorexia Induces Browning of Adipose Tissue Independent of Hypothalamic AMPK. Fraga A, Rial-Pensado E, Nogueiras R, Fernø J, Diéguez C, Gutierrez E, López M. Front Endocrinol (Lausanne). 2021 Jun 2;12:669980. doi: 10.3389/fendo.2021.669980. eCollection 2021.PMID: 34149618 

Reply to JJ Christensen et al. Zinöcker MK, Svendsen K, Levental KR, Levental I, Dankel SN. Am J Clin Nutr. 2021 Jun 1;113(6):1712-1713. doi: 10.1093/ajcn/nqab111. PMID: 34060598

Changes in lipoprotein particle subclasses, standard lipids, and apolipoproteins after supplementation with n-3 or n-6 PUFAs in abdominal obesity: A randomized double-blind crossover study. Grytten E, Laupsa-Borge J, Bohov P, Bjørndal B, Strand E, Skorve J, Nordrehaug JE, Berge RK, Rostrup E, Mellgren G, Dankel SN, Nygård OK. Clin Nutr. 2021 May;40(5):2556-2575. doi: 10.1016/j.clnu.2021.03.040. Epub 2021 Apr 3. PMID: 33933722 

Association of CYP2D6 genotype and tamoxifen metabolites with breast cancer recurrence in a low-dose trial. DeCensi A, Johansson H, Helland T, Puntoni M, Macis D, Aristarco V, Caviglia S, Webber TB, Briata IM, D'Amico M, Serrano D, Guerrieri-Gonzaga A, Bifulco E, Hustad S, Søiland H, Boni L, Bonanni B, Mellgren G. NPJ Breast Cancer. 2021 Mar 25;7(1):34. doi: 10.1038/s41523-021-00236-6. PMID: 33767162 

Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner. Quiñones M, Hernández-Bautista R, Beiroa D, Heras V, Torres-Leal FL, Lam BYH, Senra A, Fernø J, Gómez-Valadés AG, Schwaninger M, Prevot V, Yeo G, Claret M, López M, Diéguez C, Al-Massadi O, Nogueiras R. Redox Biol. 2021 May;41:101945. doi: 10.1016/j.redox.2021.101945. Epub 2021 Mar 13. PMID: 33744652

Generating a Precision Endoxifen Prediction Algorithm to Advance Personalized Tamoxifen Treatment in Patients with Breast Cancer. Helland T, Alsomairy S, Lin C, Søiland H, Mellgren G, Hertz DL. J Pers Med. 2021 Mar 13;11(3):201. doi: 10.3390/jpm11030201. PMID: 33805613 Review.

Bedtime Salivary Cortisol as a Screening Test for Cushing Syndrome in Children. Ueland GÅ, Kellmann R, Jørstad Davidsen M, Viste K, Husebye ES, Almås B, Storr HL, Sagen JV, Mellgren G, Júlíusson PB, Methlie P. J Endocr Soc. 2021 Mar 4;5(5):bvab033. doi: 10.1210/jendso/bvab033. PMID: 33928203

A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density. Sinnott-Armstrong N, Sousa IS, Laber S, Rendina-Ruedy E, Nitter Dankel SE, Ferreira T, Mellgren G, Karasik D, Rivas M, Pritchard J, Guntur AR, Cox RD, Lindgren CM, Hauner H, Sallari R, Rosen CJ, Hsu YH, Lander ES, Kiel DP, Claussnitzer M.Cell Metab. 2021 Mar 2;33(3):615-628.e13. doi: 10.1016/j.cmet.2021.01.001. Epub 2021 Jan 28.PMID: 33513366 

Role of the Neutral Amino Acid Transporter SLC7A10 in Adipocyte Lipid Storage, Obesity, and Insulin Resistance. Jersin RÅ, Tallapragada DSP, Madsen A, Skartveit L, Fjære E, McCann A, Dyer L, Willems A, Bjune JI, Bjune MS, Våge V, Nielsen HJ, Thorsen HL, Nedrebø BG, Busch C, Steen VM, Blüher M, Jacobson P, Svensson PA, Fernø J, Rydén M, Arner P, Nygård O, Claussnitzer M, Ellingsen S, Madsen L, Sagen JV, Mellgren G, Dankel SN. Diabetes. 2021 Mar;70(3):680-695. doi: 10.2337/db20-0096. Epub 2021 Jan 6.PMID: 33408126

The Female Menstrual Cycles Effect on Strength and Power Parameters in High-Level Female Team Athletes. Dasa MS, Kristoffersen M, Ersvær E, Bovim LP, Bjørkhaug L, Moe-Nilssen R, Sagen JV, Haukenes I. Front Physiol. 2021 Feb 22;12:600668. doi: 10.3389/fphys.2021.600668. eCollection 2021. PMID: 33692699 

Effect of high intake of cod or salmon on serum total neopterin concentration: a randomised clinical trial. Helland A, Bratlie M, Hagen IV, Midttun Ø, Sveier H, Mellgren G, Ueland PM, Gudbrandsen OA. Eur J Nutr. 2021 Feb 12. doi: 10.1007/s00394-021-02497-0. PMID: 33576844

The homeoviscous adaptation to dietary lipids (HADL) model explains controversies over saturated fat, cholesterol, and cardiovascular disease risk. Zinöcker MK, Svendsen K, Dankel SN. Am J Clin Nutr. 2021 Feb 2;113(2):277-289. doi: 10.1093/ajcn/nqaa322.PMID: 33471045

Hypothalamic Actions of SIRT1 and SIRT6 on Energy Balance. Quiñones M, Martínez-Grobas E, Fernø J, Pérez-Lois R, Seoane LM, Al Massadi O. Int J Mol Sci. 2021 Jan 31;22(3):1430. doi: 10.3390/ijms22031430.PMID: 33572672

Plasma 3-hydroxyisobutyrate (3-HIB) and methylmalonic acid (MMA) are markers of hepatic mitochondrial fatty acid oxidation in male Wistar rats. Bjune MS, Lindquist C, Hallvardsdotter Stafsnes M, Bjørndal B, Bruheim P, Aloysius TA, Nygård O, Skorve J, Madsen L, Dankel SN, Berge RK. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Jan 14;1866(4):158887. doi: 10.1016/j.bbalip.2021.158887. PMID: 33454435