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Norwegian Multiple Sclerosis Competence Centre and Research Group

Collage four pictures, logo in the centre.

Welcome to the Norwegian Multiple Sclerosis Competence Centre and Research Group

Contact us at: mskompetanse@helse-bergen.no


More information in Norwegian:
Norwegian Multiple Sclerosis Competence Center 
Norwegian MS-registry and biobank 

We are also part of: Neuro-SysMed (Site in Norwegian)

MS Research in Norway

Norway presents unique research opportunities because of a high prevalence of multiple sclerosis (MS) with about 12.000 patients, a government funded, universal health care system, and unique national registries. Alongside this, the Norwegian MS-Registry and Biobank now include about 7.500 patients. The unifying organization of the Norwegian Multiple Sclerosis Competence Centre at Haukeland University Hospital and the MS-Research group at the University of Bergen further strengthen the research environment. The Norwegian MS Competence Centre and Research Group is aiming to enhance diagnosis and treatment through conducting clinical trials, identifying biomarkers, and to further explore the pathology, epidemiology and clinical aspects of MS.

Location

The Norwegian Multiple Sclerosis Competence Center and Research Group is located at the Department of Neurology at Haukeland University Hospital. The research group is organized under Clinical Institute 1 at UiB and under the Norwegian Multiple Sclerosis Competence Centre. We have an extensive cooperation with local, national and international institutions, and we have an interdisciplinary structure. 

What is Multiple Sclerosis?

Multiple Sclerosis is a disease that causes multi-focal inflammatory damage and loss of nerve fiber insulation (myelin) in the central nervous system, with secondary nerve fiber (axon) damage. It is the leading non-traumatic cause of nervous system disability in young adults. Multiple Sclerosis was first described by Jean-Martin Charcot at the University of Paris in 1868. He found, on examining the brain of a deceased patient, multiple scars (sclerae, also known as plaques) that had developed in the white matter of the central nervous system. Multiple sclerosis (MS) is now thought to be an immune-mediated disease, where the insulating myelin and myelin-producing cells of the central nervous system are attacked by the patient’s own immune system. Symptoms vary according to where the lesions occur, as they cause disruption of nerve signals going through the lesion. Specific symptoms can be double vison, blindness in one eye, muscle weakness, ataxia or loss of sensory function. Several risk factors such as Epstein Bar virus infection, vitamin-D deficiency and smoking, along with complex genetic predisposition, have been identified. Still, the reason for MS development is not yet fully understood.

New dissertation in june
Agnes Nystad

Perspectives for remyelinating therapies in Multiple Sclerosis

Agnes Elisabeth Nystad presented her dissertation for the Ph.D. degree with the thesis "Perspectives for remyelinating therapies in Multiple Sclerosis" on the 12th of June 2020. This thesis provided important insight into the effects of vitamin D and fingolimod on remyelination in multiple...

New dissertation in june
Gerd Haga Bringeland

A mass cytometry receptor occupancy study of natalizumab therapy in multiple sclerosis

Gerd Haga Bringeland presented her dissertation for the Ph.D. degree with the thesis “A mass cytometry receptor occupancy study of natalizumab therapy in multiple sclerosis” on June 5 2020. This thesis contributes to the understanding of the wearing-off phenomenon experienced by many MS-patients...

What it is all about
Photo of active neuron

Multiple Sclerosis

Multiple Sclerosis (MS) is the leading non-traumatic cause of nervous system disability in young adults and represents a major burden to individuals and society.

The Norwegian Multiple Sclerosis Competence Centre and Research Group in the media

Dagens Medisin 2020.10.22: Nye MS-pasienter skal få rituksimab eller okrelizumab i Bergen

 

The Norwegian Multiple Sclerosis Competence Centre is a nationwide service for patients, family, health care personnel and other with a need for information about MS. The centre is located at Haukeland University Hospital.