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Functionalized bioactive scaffolds in bone tissue engineering

We are studying the efficacy of different techniques of functionalizing co-polymer scaffolds to deliver growth factors accountable for bone regeneration making them actively participating in the regeneration process.

We are also interested in learning more about how functionalizing the scaffolds can affect their biocompatibility after implantation, from acute tissue reactions to long-term unwanted effects like tumour formation. Using precancerous cell lines and bioluminescent imaging in severly immunodeficient mice we also work on surpassing the standard 2-year rodent carcinogenic bioassays and develop our environmentally-induced tumorigenicity noninvasive testing model.

Principal investigator: Kamal.Mustafa@iko.uib.no