Tissue Engineering

Functionalized bioactive scaffolds in bone tissue engineering

We are studying the efficacy of different techniques of functionalizing co-polymer scaffolds to deliver growth factors accountable for bone regeneration making them actively participating in the regeneration process.

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We are also interested in learning more about how functionalizing the scaffolds can affect their biocompatibility after implantation, from acute tissue reactions to long-term unwanted effects like tumour formation. Using precancerous cell lines and bioluminescent imaging in severly immunodeficient mice we also work on surpassing the standard 2-year rodent carcinogenic bioassays and develop our environmentally-induced tumorigenicity noninvasive testing model.

Principal investigator: Kamal.Mustafa@iko.uib.no