Human adipose-derived stem cells for bone tissue engineering
Mesenchymal stem cells (MSCs) isolated from bone marrow present limitations. Therefore many researchers and clinicians have investigated alternative sources of MSCs in different tissues such as dental pulp, deciduous teeth and adipose tissue. Although adipose tissue has been considered a useless tissue, recent investigations have shown that it provides an abundant source of adult stem cells.
In this project, we want to establish an improved method for isolating stem cells from human adipose tissue (ASCs). Furthermore, the proliferation ability and multi-differentiation potential of the human ASCs will be investigated to obtain high quantity and quality ASCs for clinical cell-based therapy and tissue regeneration.