Klinisk institutt 1

Midtveisevaluering - Patrick Jones

Midtveisevaluering for ph.d.-graden ved Universitetet i Bergen for kandidat Patrick Jones


Patrick Jones er tilknyttet Klinisk institutt 1. Veiledere er Øyvind Ulvik, Christian Beisland og Bhaskar Somani.


Ureteroscopy in Special Populations


The burden of kidney stone disease (KSD) is rising worldwide. This is mirrored by the increasing volume of surgical treatments being performed for this condition. Among patients with KSD, there exist a number of ‘special populations’, which can be affected by KSD and surgery can be more complex accordingly. These include those at the extremes of age, women during pregnancy, patients with abnormal anatomy such as renal transplant or previous urinary diversion, obesity and patients with bleeding diatheses.

Since ureteroscopy (URS) was first introduced to clinical practice over 40 years ago, it has undergone many advancements owing to new technologies such as next generation scopes and the introduction of laser as a modality for stone lithotripsy. To this end, URS, which is often grouped together with other minimally invasive treatments such as shockwave lithotripsy (SWL) and percutaneous lithotomy (PCNL), has become increasingly recognised as a feasible intervention when surgery is indicated in these non-indexed patients. However, as highlighted by international guidelines, further research is warranted to allow for its formal role in such complex scenarios to be delineated.

This PhD project aims to research URS in four of these special population groups: Paediatrics, Pregnancy, Elderly, and Patients with urinary diversions. The findings will serve to add to the body of literature available on surgical technique and outcomes in for these special patient groups. They can therefore serve to support and improve operative planning and surgical expertise for the benefit of patients.