- E-postaina-cathrine.overgard@uib.no
- Telefon+47 55 58 44 64
- BesøksadresseThormøhlens gate 53 A/B5006 Bergen
- PostadressePostboks 78035020 Bergen
I work at the Sea Lice Research centre with a focus on the host-parasite interaction of salmon louse (Lepeophtheirus salmonis) and Atlantic salmon as a host. We identify secretory proteins that are deposited from the lice onto the salmon to dampen immune responses.
Techniques that we use includes: transcriptomics, in situ bybridization, histology, SEM, functional studies with primary leucocytes and gene knock down (RNAi) etc
Vitenskapelig artikkel
- (2024). The ontogeny of lymphoid organs and IgM<sup>+</sup> B-cells in ballan wrasse (Labrus bergylta) reveals a potential site for extrarenal B-cell lymphopoiesis: The pancreas. Fish and Shellfish Immunology.
- (2024). Salmon louse labial gland enzymes: implications for host settlement and immune modulation. Frontiers in Genetics.
- (2023). Transcriptomic and targeted immune transcript analyses confirm localized skin immune responses in Atlantic salmon towards the salmon louse. Fish and Shellfish Immunology. 16 sider.
- (2023). The thymus and T-cell ontogeny in ballan wrasse (Labrus bergylta) is nutritionally modelled. Frontiers in Immunology. 19 sider.
- (2023). Mining Lepeophtheirus salmonis RNA-Seq data for qPCR reference genes and their application in Caligus elongatus. Experimental parasitology.
- (2023). Identification and characterization of two salmon louse heme peroxidases and their potential as vaccine antigens. iScience. 21 sider.
- (2022). Small, charged proteins in salmon louse (Lepeophtheirus salmonis) secretions modulate Atlantic salmon (Salmo salar) immune responses and coagulation. Scientific Reports. 16 sider.
- (2021). Roles of three putative salmon louse (Lepeophtheirus salmonis) prostaglandin E2synthases in physiology and host–parasite interactions. Parasites & Vectors. 17 sider.
- (2020). Rainbow trout Oncorhynchus mykiss skin responses to salmon louse Lepeophtheirus salmonis: From copepodid to adult stage. Fish and Shellfish Immunology. 200-210.
- (2018). Salmon louse rhabdoviruses: Impact on louse development and transcription of selected Atlantic salmon immune genes. Developmental and Comparative Immunology. 86-95.
- (2018). Genomic characterization, phylogenetic position and in situ localization of a novel putative mononegavirus in Lepeophtheirus salmonis. Archives of Virology. 675-689.
- (2017). RNAi-mediated treatment of two vertically transmitted rhabdovirus infecting the salmon louse (Lepeophtheirus salmonis). Scientific Reports. 1-10.
- (2017). Molecular characterization and functional analysis of a salmon louse (Lepeoptheirus salmonis, Krøyer 1838) heme peroxidase with a potential role in extracellular matrixes. Comparative Biochemistry and Physiology A. 1-10.
- (2017). Characterization of three salmon louse (Lepeophtheirus salmonis) genes with fibronectin II domains expressed by tegumental type 1 glands. Molecular and biochemical parasitology (Print). 1-9.
- (2016). Exocrine glands of Lepeophtheirus salmonis (Copepoda: Caligidae): Distribution, developmental appearance, and site of secretion. Journal of morphology. 1616-1630.
- (2015). Molecular characterization and knock-down of salmon louse (Lepeophtheirus salmonis) prostaglandin E synthase. Experimental parasitology. 79-93.
- (2014). Genomic characterization and phylogenetic position of two new species in Rhabdoviridae infecting the parasitic copepod, salmon louse (Lepeophtheirus salmonis). PLOS ONE.
- (2014). A new intracellular bacterium, Candidatus Similichlamydia labri sp. nov. (Chlamydiaceae) producing epitheliocysts in ballan wrasse, Labrus bergylta (Pisces, Labridae). Archives of Microbiology. 311-318.
- (2013). Atlantic halibut (Hippoglossus hippoglossus L.) T-cell and cytokine response after vaccination and challenge with nodavirus. Vaccine. 2395-2402.
- (2012). Characterisation and expression analysis of the Atlantic halibut (Hippoglossus hippoglosssus L.) cytokines: IL-1β, IL-6, IL-11, IL-12β and IFNγ. Molecular Biology Reports. 2201-2213.
- (2012). Atlantic halibut experimentally infected with nodavirus shows increased levels of T-cell marker and IFN gamma transcripts. Developmental and Comparative Immunology. 139-150.
- (2011). Expression of T-cell markers during Atlantic halibut (Hippoglossus hippoglossus L.) ontogenesis. Developmental and Comparative Immunology. 203-213.
- (2010). Evaluation of potential reference genes for real time RT-PCR studies in Atlantic halibut (Hippoglossus Hippoglossus L.); during development, in tissues of healthy and NNV-injected fish, and in anterior kidney leucocytes. BMC Molecular Biology. 15 sider.
- (2010). Cloning, characterization, and expression pattern of Atlantic halibut (Hippoglossus hippoglossus L.) CD4-2, Lck, and ZAP-70. Fish and Shellfish Immunology. 987-997.
- (2009). Cloning and expression analysis of Atlantic halibut (Hippoglossus hippoglossus) CD3 genes. Fish and Shellfish Immunology. 707-713.
- (2009). A CD4 homologue in Atlantic halibut (Hippoglossus hippoglossus): Molecular cloning and characterisation. Fish and Shellfish Immunology. 377-384.
- (2008). CD8 alpha and CD8 beta in Atlantic halibut, Hippoglossus hippoglossus: Cloning, characterization and gene expression during viral and bacterial infection. Fish and Shellfish Immunology. 570-580.
Rapport
- (2014). Sekvensering av havet – fremtidens teknologi. .
Vitenskapelig foredrag
- (2023). Omlegging fra tradisjonelle forelesninger til studentaktiv læring – eksempel fra et grunnemne i biolog.
- (2022). Does Salmon louse Have an Immune Dampening Effect on Atlantic Salmon? .
- (2020). Grunnleggende lusebiologi – hva vet vi, og hva skal studeres. .
- (2019). THE SALMON LOUSE (LEPEOPHTHEIRUS SALMONIS) SALIVARY GLAND SECRETES IMMUNE REGULATORY PROTEINS.
- (2019). Lusespytt modulerer laksens immunrespons.
- (2019). Learning outcomes at master level in biology. Current expectations and guidelines for the future.
- (2018). MORPHOLOGICAL AND IMMUNOLOGICAL CHANGES IN RAINBOW TROUT SKIN IN RESPONSE TO SALMON LOUSE INFECTION.
- (2018). Excretory and Secretory Factors of the Salmon Louse: Genomic Characterization, Effects on Feeding, and Impacts on Host Immunity.
- (2018). DO Lepeophtheirus salmonis RHABDOVIRUSES (LsRVs) DAMPEN THE LOCAL SKIN INFLAMMATORY RESPONSE IN ATLANTIC SALMON Salmo salar?
- (2017). Exocrine glands of Lepeophtheirus salmonis and secretion of possible immune regulatory proteins.
- (2017). Do prostaglandins produced by lepeophtheirus salmonis affect the interaction between the parasite and the fish?
- (2016). Distribution and Development of salmon louse Lepeophtheirus salmonis exocrine glands.
- (2014). Characterization and knock-down of a putative prostaglandin e synthase found in Lepeophtheirus salmonis.
- (2010). Molecular approaches for development of vaccines against intracellular fish pathogens.
- (2009). Relativ uttrykning av T-celle markører i tidlige livsstadier hos Atlantisk kveite (Hippoglossus hippoglossus).
- (2009). B and T cell markers during Atlantic halibut (Hippoglossus hippoglossus) ontogenesis.
Mastergradsoppgave
- (2021). Refilling behaviour of Atlantic salmon (Salmo salar) with different air-dome heights.
Populærvitenskapelig artikkel
- (2020). Skottelusen: en kilde til viktig kunnskap, men også en mulig fremtidig trussel? Norsk Fiskeoppdrett.
Doktorgradsavhandling
- (2012). T-cells and cytokines of Atlantic halibut (Hippoglossus hippoglossus L.) - Gene expression levels during ontogenesis, vaccination and experimental nodavirus infection.
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
- (2011). Viruses of Fish. 39 sider.
Sammendrag/abstract
- (2023). LsLGP3 from Salmon Louse (Lepeophtheirus salmonis) Causes Cell Death in Atlantic salmon (Salmo salar) Leukocytes. Developmental and Comparative Immunology. 104980.
Poster
- (2017). Eksokrine kjertler i lakselus (Lepeophtheirus salmonis).
- (2016). Licebase-a species focused resource for sea lice including an RNAi LIMS andtools for data analysis and genome annotation.
Populærvitenskapelig kapittel/artikkel
- (2011). Tidlig vaksinering – mot sin hensikt. 41-42.