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Kristian Smeland Ytre-Hauges bilde

Kristian Smeland Ytre-Hauge

Professor, Prosjektleder for mikrodosimetri i partikkelterapi - 3D microdosimetry and studies of the Relative Biological Effectiveness (RBE) in proton- and carbon ion therapy
  • E-postkristian.ytre-hauge@uib.no
  • Telefon+47 55 58 27 81
  • Besøksadresse
    Allégaten 55
    5007 Bergen
    Rom 
    527
  • Postadresse
    Postboks 7803
    5020 Bergen
Teaching experience

I am a professor at the department of physics and technology at UiB. My discipline is medical phyiscs and my main focus is the use of ionizing radiation, such as X-rays, for treatment of cancer (radiotherapy) and medical imaging. I am active in teaching, research and supervision of students at the master and PhD level. This portfolio describes my teaching experience, development and philosophy and aim to provide insight into how I have developed my teaching over time aiming at increased student learning and thoughts on how I can develop further.

I have been teaching regularly at the Master level at UiB for nine years. My teaching experience is briefly summarized in the table below. My work to develop and improve my teaching and the students learning is described in the following paragraphs and in my teaching philosophy at the end of this document. Examples of teaching materials are available in a separate attachment.

 

 

Formal pedagogical training

The table below gives an overview of pedagogical courses taken at UiB. As indicated in the table, three of the courses are ongoing and soon completed. See separate attachment for details and documentation regarding this.

Year

 

2022

UPED 602 (fall) – Pedagogical project (Ongoing) 50 Hours

UPED 652 (fall) - Advanced Teaching in Mitt UiB : Visual Design (Ongoing) 15 Hours

UPED 659 (fall) - Creating Effective Discussions to Promote Learning (Ongoing) 15 Hours

UPED 601 (spring) – Documenting and evaluating teaching 36 Hours

UPED 676 (spring) - Creating Accessible Teaching and Learning Materials 15 Hours

2021

UPED 600 – Introduction to university teaching and class design 24 Hours

UPED 650 - Online and Blended Learning 30 Hours

2015

UPED622 – Research supervison/counseling, UiB 30 Hours

Sum

A total of 215 Hours

 

 

 

 

Year

 

2015 -  present

 

Master level teaching, UiB. Phys 213 – The physics of radiotherapy. Role: Course organizer and lecturer

2017- present

Bachelor level teaching, UiB. MTEK 100 – Medical technology in practice. Lecturer.

2017, 2020.

Master/PhD level teaching, NTNU - FY8412: Ionizing radiation, interactions and dosimetry, External lecturer

 

2013

Master level teaching, UiB. Phys 231 – Radiation physics. Role: Teaching assistant – lectures and exercises

 

Supervision experience

I have long and broad experience from supervision of master and phd students as summarized in the table below.

Master's students

Ph.D.
students

 

20+

10

Main supervisor for 5 PhD students in the field of particle therapy (UiB, Dept. of physics and technology). Four completed PhD theses and one ongoing. Co-supervisor for 5 PhD students (1 graduated, 4 ongoing). Supervisor for more than 20 master students (mainly as main supervisor).

 

Educational research contributions

Students and supervisors view on the role of the master supervisor. Scientific poster in preparation (in connection with the UPED 602 course)

A guide to master thesis writing. Kristian S Ytre-Hauge and Audun O. Pedersen. A written guide ((https://hdl.handle.net/11250/3065441).) for master students regarding preparations and writing of a master thesis (in connection with the UPED 602 course)

 

Production of learning resources

For teaching in medical physics, I have developed project tasks, exercises, quizzes, lectures, canvas modules for asynchronous work and educational videos for students. Examples of these teaching materials are available in a separate attachment. Instructional videos have also been developed to guide master students in use of relevant software for radiation transport simulations in medical physics. To facilitate better learning I also use the technique of 3-minute papers – registering what students remember from a lecture – serving as repetition for the student and as guidance for me as a teacher

Collaboration in teaching

In my teaching I have collaborated with colleagues in many different ways. In my main field of teaching, I have had a very close collaboration with radiation physicists at Haukeland University Hospital (HUS) to ensure teaching relevant for the medical physics community where many of the students are employed after their studies. I have also taught at another university (NTNU) in a collaborative course aiming first and foremost to increase the knowledge of already graduated students who work as clinical medical physicists. In collaboration with X-ray physicists at HUS I have also guided students at the MTEK programme at UiB. Collaboration with colleagues locally, nationally and international has also been central in supervision of students at master and PhD level.

In addition, I have been member of the working group for development of teaching at the department of physics and technology. We have covered several topic including “lessons from digital teaching during covid”, “evaluation of students – ‘to-sensor-ordningen’ ” and “classroom tools and equipment at our department” and now also discussing supervision of master students.

Experience from teaching, development and evaluation of teaching

Through seven years of teaching and organizing PHYS213 at UiB I have each year updated and hopefully improved my lectures and teaching material. This has been required both to increase the quality of the teaching but also because medical physics is a field that rapidly develops with new types of applications and treatments. I have particularly focused on making the structure and content of the course more logical and “chronological” while still giving some repetition of key issues and topics. In 2021 I did a complete revision of the learning outcome descriptions for PHYS213. For this purpose I found the Blooms taxonomy in Norwegian (from: “kvalitetslæring i høgare utdanning» R. C. Petterse) very useful. After that I have also revised the content and removed materials which I believe do not contribute to reaching the learning outcomes. In 2022 I expanded the course with an extension for PhD-students in collaboration with my colleague Sara Pilskog. On two occasions I have received feedback on my teaching from anonymous student questionnaires giving valuable input for adjusting my teaching methods and materials. I have also given and received teaching evaluations to/from colleagues which in my opinion also gives very valuable insights (see separate attachment for details). I also have experience from evaluating master and bachelor thesis.

Teaching philosophy

I am an associate professor at the department of physics and technology at UiB. My discipline is medical phyiscs and my main focus is the use of ionizing radiation, such as X-rays, for treatment of cancer (radiotherapy) and medical imaging. I am active in teaching, research and supervision of students at the master and PhD level. After seven years as course organizer and lecturer in medical physics (PHYS213) at UiB, and also teaching other courses at UiB and elsewhere I have already gained quite some experience in teaching. These years have been a process of learning and hopefully improving my own teaching based on feedback from students, colleagues, and my own reflections. The learning process has been both in terms of a deeper physics understanding and in the pedagogical perspective.

Until 2021, I had little formal pedagogical training and very limited knowledge of theory and literature on teaching and learning in higher education. In 2021 and 2022 I have participated in the pedagogical UPED courses at UiB which have given me the opportunity to see and evaluate my own teaching in a broader perspective and given me a range of pedagogical tools and knowledge which I already believe have had a positive impact on my teaching and student learning. My interpretation of the main take home message altogether from these courses is as simple as moving the focus from teaching to student learning. While the message may be simple a researcher mindset is in my opinion needed to truly achieve progress in the teaching and student learning.  This is part of the rationale for introducing the concept of Scholarship of Teaching and Learning (SoTL) [Boyer, 1990]. The SoTL way of thinking could be summarized as inquiry focused on student learning [Flatten, 2013], but grounded in both scholarly and local context, i.e. using knowledge and methodology from research but also in partnership with students and colleagues.

I have a clear goal of making use of what I have learned in the UPED courses to improve and diversify my teaching in the future. One particular aspect I have already engaged in more is the collaboration and exchange of thoughts and knowledge with colleagues. As part of a committee for improved teaching at my department I have participated in discussions ranging from practicalities in the classroom (e.g. use of blackboard power point slides etc.) to supervision style and methodology.

Student learning from my perspective requires that students first have understood the background and context for the subject I am teaching. I believe that only when this is achieved, the student will be able to efficiently learn and understand the relevance of what is being taught. Without any context, I believe student motivation will be lower and more focused towards the exam than towards true learning. I therefore try to focus on not only the hard facts of the physics courses I am teaching but also why theses facts matter and are important to know. I have also increased my attention towards the learning outcome of each teaching activity. As discussed by Biggs [Biggs 2003], teching should strive for constructive allignment, e.g. alignment between the learning outcome we want, the teaching activities and also the evaluation of the students’ learning. In terms of evaluation of students or exams, this is a topic I have debated with my colleagues quite a bit, particularly in light of new regulations which may be introduced in 2023 – demanding two independent evaluations of works who contribute to determine the grades of the students. This is a challenge as I personally would like to base the grades on project works of different kinds in addition to a potential final exam. I think this is a topic which will be of great importance to work actively with in the future and I hope I will be able to continue with evaluations beyond a single final exam.

In my teaching, my objective is for the student to achieve the learning outcomes and also be able to apply this knowledge after they graduate. In my lectures I therefore strive to connect the theory of medical physics and radiotherapy to real life examples, exercises or situations which may occur working as a medical physicist or researcher. I have also over the past few years attempted to reduce the number of traditional lectures in favour of more student active learning. Examples of activities I have introduced are small group discussions or problem solving, topic specific quizzes using the Socrative-software. By letting the students work in small groups of 2-4 participants I find that students become more active and engage in important discussions with their fellow students. This kind of peer instruction is also well founded in the pedagogical literature in general and also within the field of physics as show e.g. by Bozzi et al [Bozzi, 2018] These activities also serve as a break from lectures and, in my opinion, increases the students’ attention to the now shorter sections of traditional lecture which are mixed with the student active activities. In the more pure lectures I still believe it is possible to avoid a monotonous style. I therefore try to combine the use of blackboard, power point slides and, if possible, practical/computer based demonstrations. To facilitate better learning I have also the past year begun to use the technique of 3-minute papers – registering what students remember from a lecture – serving as repetition for the student and as guidance for me as a teacher.

I believe in the use of modern technology in teaching. In the UPED course blended learning I got further insights into the possibilities of combining in-classroom teaching with so-called asynchronous work where the students work independently or in groups without a teacher present. The Canvas tool at the student portal MittUiB used at UiB brings a broad range of possibilities which I have only over the past year begun to explore and apply. To make video lectures I have used the tool Kaltura, but also for shorter videos, simply used my phone or Zoom. The different options have their advantages and disadvantages e.g. with respect to audio/video quality vs ease of use and possibilities for editing. I still believe that the use of videos should be a supplement rather than a replacement for in classroom teaching as important discussions and room for questions may be missed. I have therefore mainly made shorter videos explaining concepts or tools e.g. required to solve exercises or as an introduction to a new topic. Examples of such teaching material developed by me is available in a separate attachment.

In addition to university level teaching, I have broad experience from scientific presentations at national and international conferences. For such presentations I seek to communicate in a natural and engaged manner and avoid following a predefined script. In my opinion a presenter should know the content of his/her work to the extent that there is no need for a script, but rather the presentation should flow naturally like in a discussion or conversation with a colleague or a friend.

Regarding supervision of students my philosophy is that frequent meetings and an open door policy is a good way to achieve a good collaboration with the student. Students are diverse and while some students may thrive and move their project with less frequent support, most student benefit from a clear structure with respect to frequency and form of supervision meetings and guidance. I also strongly believe that it is a great benefit to have more than one supervisor, both in terms of diversity in the guidance of the students and also giving the student other possibilities if they for any reason feel communication is challenging with one of the supervisors. In my supervision, I have invited colleagues with complementary expertise to co-supervise my students. Through the UPED 622 course I gained valuable insights into the role of the supervisor and now through the UPED 602 course I’m performing a pedagogical study regarding the supervision done for master students at our department and how we can improve this. This is a topic of great interest for me and while the project is in a data collection stage now, we will soon analyse the input from students and supervisors regarding how supervision is done, and how it could improve.

To summarize, I have learned from i) my own Personal Experience, ii) from Colleagues, iii) Students and iv) Theory - how to improve my teaching. In my opinion, I take small steps in my own development each year. I have systematically worked to revise and improve the teaching materials in my courses as well as improve the way I teach.  A very significant boost in this effort has come from the UPED courses and I look forward to focus on improving student learning using these four “lenses” mentioned above as described by Brokenfield [Brokenfield 2017]  as essential to be a critically reflective teacher: The students’ eyes, Colleagues perceptions, Personal experience and Theory.

References

Biggs, J. (2003). Aligning teaching for constructing learning. Higher Education Academy 1(4).

Boyer, E. L. (1990). Scholarship Reconsidered (1 ed.). San Francisco: Jossey-Bass Publishers

Bozzi, M et al (2018). Peer learning for large size Physics lectures in higher education: yes, we can.

ISBN 978-84-09-05948-5

Brookfield, S.D. (2017) Becoming a Critically Reflective Teacher. John Wiley & Sons, Incorporated.

Felten, P. (2013). Teaching & Learning Inquiry: The ISSOTL Journal Vol. 1, No. 1 (2013), pp. 121-125 (5 pages)

Vitenskapelig artikkel
  • Vis forfatter(e) (2023). Prompt gamma-ray spectroscopy in conjunction with the Monte Carlo Library Least Squares approach: applications to range verification in proton therapy . The European Physical Journal Conferences. 6 sider.
  • Vis forfatter(e) (2023). Linear energy transfer-inclusive models of brainstem necrosis following proton therapy of paediatric ependymoma. Physics and imaging in radiation oncology (PIRO).
  • Vis forfatter(e) (2023). Influence of beam pruning techniques on LET and RBE in proton arc therapy. Frontiers in Oncology.
  • Vis forfatter(e) (2023). Efficacy and User Experience of a Novel X-Ray Shield on Operator Radiation Exposure during Cardiac Catheterization: A Randomized Controlled Trial. Circulation. Cardiovascular Interventions. 745-753.
  • Vis forfatter(e) (2023). Combined RBE and OER optimization in proton therapy with FLUKA based on EF5-PET. Journal of Applied Clinical Medical Physics. 11 sider.
  • Vis forfatter(e) (2023). A systematic approach for calibrating a Monte Carlo code to a treatment planning system for obtaining dose, LET, variable proton RBE and out-of-field dose. Physics in Medicine and Biology.
  • Vis forfatter(e) (2023). A hybrid multi-particle approach to range assessment-based treatment verification in particle therapy. Scientific Reports. 16 sider.
  • Vis forfatter(e) (2022). Hypoxia adapted relative biological effectiveness models for proton therapy: a simulation study. Biomedical Engineering & Physics Express. 13 sider.
  • Vis forfatter(e) (2022). Effect of an optimized X-ray blanket design on operator radiation dose in cardiac catheterization based on real-world angiography. PLOS ONE.
  • Vis forfatter(e) (2022). A hybrid multi-particle approach to range assessment-based treatment verification in particle therapy. Research Square.
  • Vis forfatter(e) (2022). A case-control study of linear energy transfer and relative biological effectiveness related to symptomatic brainstem toxicity following pediatric proton therapy. Radiotherapy and Oncology. 47-55.
  • Vis forfatter(e) (2021). The Organ Sparing Potential of Different Biological Optimization Strategies in Proton Therapy. Advances in Radiation Oncology.
  • Vis forfatter(e) (2020). Variation in relative biological effectiveness for cognitive structures in proton therapy of pediatric brain tumors. Acta Oncologica. 1-9.
  • Vis forfatter(e) (2020). The FLUKA Monte Carlo code coupled with an OER model for biologically weighted dose calculations in proton therapy of hypoxic tumors. Physica Medica. 166-172.
  • Vis forfatter(e) (2020). Spatial agreement of brainstem dose distributions depending on biological model in proton therapy for pediatric brain tumors. Advances in Radiation Oncology. 1-9.
  • Vis forfatter(e) (2020). Plan selection in proton therapy of locally advanced prostate cancer with simultaneous treatment of multiple targets. International Journal of Radiation Oncology, Biology, Physics. 630-638.
  • Vis forfatter(e) (2020). Microdosimetry with a 3D silicon on insulator (SOI) detector in a low energy proton beamline. Radiation Physics and Chemistry.
  • Vis forfatter(e) (2020). Inter-patient variations in relative biological effectiveness for cranio-spinal irradiation with protons. Scientific Reports. 1-9.
  • Vis forfatter(e) (2020). Implementation of a double scattering nozzle for Monte Carlo recalculation of proton plans with variable relative biological effectiveness. Physics in Medicine and Biology. 1-20.
  • Vis forfatter(e) (2019). The experimental dose ranges influence the LETd dependency of the proton minimum RBE (RBEmin). Physics in Medicine and Biology. 1-10.
  • Vis forfatter(e) (2019). First application of a novel SRAM-based neutron detector for proton therapy. Radiation Measurements. 45-52.
  • Vis forfatter(e) (2019). A Monte Carlo feasibility study for neutron based real-time range verification in proton therapy. Scientific Reports. 1-9.
  • Vis forfatter(e) (2018). Sensitivity study of the microdosimetric kinetic model parameters for carbon ion radiotherapy. Physics in Medicine and Biology. 1-14.
  • Vis forfatter(e) (2018). Exploration and application of phenomenological RBE models for proton therapy. Physics in Medicine and Biology. 1-21.
  • Vis forfatter(e) (2017). The influence of inter-fractional anatomy variation on secondary cancer risk estimates following radiotherapy. Physica Medica. 271-276.
  • Vis forfatter(e) (2017). The FLUKA Monte Carlo code coupled with the NIRS approach for clinical dose calculations in carbon ion therapy. Physics in Medicine and Biology. 3814-3827.
  • Vis forfatter(e) (2017). Monte Carlo simulations of a low energy proton beamline for radiobiological experiments. Acta Oncologica. 779-786.
  • Vis forfatter(e) (2017). Linear energy transfer distributions in the brainstem depending on tumour location in intensity-modulated proton therapy of paediatric cancer. Acta Oncologica. 763-768.
  • Vis forfatter(e) (2017). Biological dose and complication probabilities for the rectum and bladder based on linear energy transfer distributions in spot scanning proton therapy of prostate cancer. Acta Oncologica. 1413-1419.
  • Vis forfatter(e) (2017). A phenomenological biological dose model for proton therapy based on linear energy transfer spectra. Medical Physics (Lancaster). 2586-2594.
  • Vis forfatter(e) (2016). Modelling of organ-specific radiation-induced secondary cancer risks following particle therapy. Radiotherapy and Oncology. 300-306.
  • Vis forfatter(e) (2015). Risk of radiation-induced secondary rectal and bladder cancer following radiotherapy of prostate cancer. Acta Oncologica. 1317-1325.
  • Vis forfatter(e) (2015). Design and characterization of an SRAM-based neutron detector for particle therapy. Nuclear Instruments and Methods in Physics Research Section A : Accelerators, Spectrometers, Detectors and Associated Equipment. 64-71.
  • Vis forfatter(e) (2014). Estimated risk of radiation-induced cancer following paediatric cranio-spinal irradiation with electron, photon and proton therapy. Acta Oncologica. 1048-1057.
Faglig foredrag
  • Vis forfatter(e) (2022). An approach for obtaining Monte Carlo computed dose and variable proton RBE from a treatment planning system.
Vitenskapelig foredrag
  • Vis forfatter(e) (2023). Prompt gamma-ray spectroscopy in conjunction with the Monte Carlo Library Least Squares approach: applications to range verification in proton therapy .
  • Vis forfatter(e) (2023). In vitro Data Selection Strongly impact RBE model predictions.
  • Vis forfatter(e) (2023). In silico estimation and mitigation of operator dose during X-ray image guided interventional procedures  .
  • Vis forfatter(e) (2023). Impact of an updated in vitro database on proton relative biological effectiveness modelling.
  • Vis forfatter(e) (2022). Proton therapy treatment verification with prompt gamma rays and fast neutrons – a feasibility study.
  • Vis forfatter(e) (2022). NOVO-prosjektet: In-vivo dosimetri for protonterapi gjennom kombinert måling av produserte nøytroner og prompt gamma-stråling.
  • Vis forfatter(e) (2022). Influence of beam pruning techniques on LET and RBE in proton arc therapy.
  • Vis forfatter(e) (2022). In vitro-based Modelling of Proton Relative Biological Effectiveness: Testing the assumption of an inverse proportionality with (𝛼∕𝛽)_𝑥.
  • Vis forfatter(e) (2022). En systematisk metode for å beregne variabel RBE fra et doseplansystem for protonterapi ved hjelp av Monte Carlo.
  • Vis forfatter(e) (2022). A novel approach for obtaining Monte Carlo computed dose and variable RBE from a treatment planning system .
  • Vis forfatter(e) (2021). Multi-Feature Treatment Verification in Particle Therapy.
  • Vis forfatter(e) (2020). Multi-Feature Reichweiteverifikation in der Partikeltherapie.
  • Vis forfatter(e) (2019). Very high RBE values found at the distal end of the proton Bragg peak.
  • Vis forfatter(e) (2018). Performance of pillar shaped plastic scintillators for neutron based range verification in proton therapy .
  • Vis forfatter(e) (2017). A high-resolution proton irradiator for in vitro studies of relative biological effectiveness.
Mastergradsoppgave
  • Vis forfatter(e) (2009). Measurements of Neutron Doses from Radiotherapy with 12C Ions and Photons.
Brev til redaktøren
  • Vis forfatter(e) (2023). Linear energy transfer-inclusive brainstem necrosis risk models applied to an independent paediatric proton therapy cohort. Acta Oncologica.
  • Vis forfatter(e) (2023). Dose exposure to an adult present in the treatment room during pediatric pencil beam scanning proton therapy. Acta Oncologica.
Doktorgradsavhandling
  • Vis forfatter(e) (2019). Analysis and Development of Phenomenological Models for the Relative Biological Effectiveness in Proton Therapy.
  • Vis forfatter(e) (2013). Measurements and Monte Carlo Simulations of Neutron Doses from Radiation Theraphy with Photons, Protons and Carbon Ions.
Sammendrag/abstract
  • Vis forfatter(e) (2019). Very high yield of double strand breaks found at the distal end of the proton Bragg peak. Radiotherapy and Oncology. 594-594.
  • Vis forfatter(e) (2018). Very high relative biological effectiveness found at the distal end of the proton Bragg peak. Radiotherapy and Oncology. 1259-1259.
  • Vis forfatter(e) (2017). Monte Carlo simulations of a low-energy proton beam and estimation of LET distributions. Radiotherapy and Oncology. 179-180.
Poster
  • Vis forfatter(e) (2023). The neutron contribution in pediatric proton therapy depends on field angle configuration .
  • Vis forfatter(e) (2023). Robustness evaluation of linear energy transfer in proton therapy of paediatric brain tumours.
  • Vis forfatter(e) (2023). Radiation-induced cancer risk from neutrons in pediatric proton therapy and field angle dependence.
  • Vis forfatter(e) (2023). Radiation exposure to a parent-in-the-treatment-room during pencil beam scanning proton therapy.
  • Vis forfatter(e) (2023). Linear energy transfer based optimisation to minimise normal tissue complication probability in paediatric ependymomas.
  • Vis forfatter(e) (2023). Influnce of LET and RBE from including pruning techniques in proton arc therapy.
  • Vis forfatter(e) (2023). First application of an LET-inclusive NTCP model for brainstem necrosis following paediatric proton therapy in an independent cohort.
  • Vis forfatter(e) (2022). NOVO - Neutron and Prompt Gamma-Ray Range Verification in Particle Therapy.
  • Vis forfatter(e) (2022). Effects of Data Selection and Model Assumptions for Modelling of Proton Relative Biological Effectiveness.
  • Vis forfatter(e) (2022). Effects of Data Selection and Model Assumptions for Modelling of Proton Relative Biological Effectiveness.
  • Vis forfatter(e) (2022). A novel approach for obtaining Monte Carlo computed dose and variable proton RBE from a treatment planning system.
  • Vis forfatter(e) (2021). Neutron-based in-vivo range verification in proton therapy.
  • Vis forfatter(e) (2018). The NOVO project: NeutrOn detection for real-time range VerificatiOn in proton therapy – A Monte Carlo feasibility study .
Errata
  • Vis forfatter(e) (2019). Author Correction: A Monte Carlo feasibility study for neutron based real-time range verification in proton therapy (Scientific Reports, (2019), 9, 1, (2011), 10.1038/s41598-019-38611-w). Scientific Reports.

Se fullstendig oversikt over publikasjoner i CRIStin.

LIST OF PUBLICATIONS – Kristian Smeland Ytre-Hauge

  1. Stokkevåg CH, Engeseth GM, Ytre-Hauge K, Røhrich D, Odland OH, Muren LP, Hysing LB, Brydøy M, Szostak AK, Palmer MP, Petersen JBB. Estimated risk of radiation-induced cancer following paediatric cranio-spinal irradiation with electron, photon and proton therapy. Acta Oncol, 2014. 53(8): p. 1048-57.
  2. Stokkevåg CH, Engeseth GM, Hysing LB, Ytre-Hauge KS, Ekanger C, Muren LP. Risk of radiation-induced secondary rectal and bladder cancer following radiotherapy of prostate cancer. Acta Oncol, 2015. 54(9): p. 1317-25.
  3. Ytre-Hauge KS, Velure A, Larsen EF, Stokkevåg CH, Röhrich D, Brekke N, Odland OH. Design and Characterization of an SRAM-based Neutron Detector for Particle Therapy. Nucl Instrum Meth A 2015. 804: p. 64-71.
  4. Stokkevåg CH, Fukahori M, Nomiya T, Matsufuji N, Engeseth GM, Hysing LB, Ytre-Hauge KS, Szostak A, Muren LP. Modelling of organ-specific radiation-induced secondary cancer risks following particle therapy. Radiother Oncol 2016 Volume 120, Issue 2: p 300-6
  1. Rørvik E, Thörnqvist S, Stokkevåg C H, Dahle T J, Fjæra L F and Ytre-Hauge K S 2017 A phenomenological biological dose model for proton therapy based on linear energy transfer spectra Medical physics 44 2586-94

 

  1. Stokkevåg C H, Engeseth G M, Hysing L B, Ytre-Hauge K S and Muren L P. 2017. The influence of inter-fractional anatomy variation on secondary cancer risk estimates following radiotherapy Physica Medica 42 271-6
  2. Dahle T J, Rykkelid A M, Stokkevåg C H, Mairani A, Görgen A, Edin N J, Rørvik E, Fjæra L F, Malinen E and Ytre-Hauge K S. 2017. Monte Carlo simulations of a low energy proton beamline for radiobiological experiments. Acta Oncologica, 1-8, doi:10.1080/0284186X.2017.1289239 (2017).

 

  1. Magro G, Dahle T J, Molinelli S, Ciocca M, Fossati P, Ferrari A, Inaniwa T, Matsufuji N, Ytre-Hauge K S and Mairani A 2017 The FLUKA Monte Carlo code coupled with the NIRS approach for clinical dose calculations in carbon ion therapy Phys Med Biol 62 3814-27

 

  1. Fjaera L F, Li Z, Ytre-Hauge K S, Muren L P, Indelicato D J, Lassen-Ramshad Y, Engeseth G M, Brydoy M, Mairani A, Flampouri S, Dahl O and Stokkevag C H 2017 Linear energy transfer distributions in the brainstem depending on tumour location in intensity-modulated proton therapy of paediatric cancer Acta Oncol 56 763-8

 

  1. Pedersen J, Petersen J B B, Stokkevag C H, Ytre-Hauge K S, Flampouri S, Li Z, Mendenhall N and Muren L P 2017 Biological dose and complication probabilities for the rectum and bladder based on linear energy transfer distributions in spot scanning proton therapy of prostate cancer Acta Oncol 56 1413-9
  1. Ytre-Hauge KS, Velure A, Stokkevåg CH, Odland OH, Röhrich D. First application of a novel SRAM-based neutron detector for proton therapy. Radiat Meas 122, 45-52, doi:10.1016/j.radmeas.2019.01.001 (2019).
  1. Ytre-Hauge, K. S., Skjerdal, K., Mattingly, J. & Meric, I. A Monte Carlo feasibility study for neutron based real-time range verification in proton therapy. Sci Rep-Uk 9, 2011, doi:10.1038/s41598-019-38611-w (2019).
  1. Eivind Rørvik, Lars Fredrik Fjæra, Tordis J. Dahle, Jon Espen Dale, Grete May Engeseth, Camilla H. Stokkevåg, Sara Thörnqvist and  Kristian S. Ytre-Hauge. Exploration and application of phenomenological RBE models for proton therapy. Phys Med Biol 63, 185013, doi:10.1088/1361-6560/aad9db (2018).
  2. T J Dahle, G Magro, K S Ytre-Hauge, C H Stokkevåg, K Choi, A Mairani. Sensitivity study of the microdosimetric kinetic model parameters for carbon ion radiotherapy. Physics in Medicine and Biology, doi:10.1088/1361-6560/aae8b4 (2018).
  1. Eivind, Rørvik., Sara, Thörnqvist & Kristian S Ytre-Hauge. The experimental dose ranges influence the LETd dependency of the proton minimum RBE (RBEmin). Phys Med Biol 64, 195001, doi:10.1088/1361-6560/ab369a (2019).
  1. Sara Pilskog, Bonny Abal, Kaja S. Øvrelid, Grete May Engeseth, Kristian S. Ytre-Hauge and Liv B. Hysing. Plan Selection in Proton Therapy of Locally Advanced Prostate Cancer with Simultaneous Treatment of Multiple Targets. International Journal of Radiation Oncology • Biology • Physics 106, 630-638, doi:10.1016/j.ijrobp.2019.11.007 (2020).

 

  1. Kristian S. Ytre-Hauge, Lars Fredrik Fjæra, Eivind Rørvik, Tordis J. Dahle, Jon Espen Dale,

Sara Pilskog & Camilla H. Stokkevåg. Inter-patient variations in relative biological effectiveness for cranio-spinal irradiation with protons. Sci Rep 10, 6212, doi:10.1038/s41598-020-63164-8 (2020).

  1. AT Samnøy, KS Ytre-Hauge, E Malinen, L Tran, A Rosenfeld, M Povoli, A Kok, A Summanwar, D Röhrich. Microdosimetry with a 3D silicon on insulator (SOI) detector in a low energy proton beamline. Radiat Phys Chem 176, 109078, doi:10.1016/j.radphyschem.2020.109078 (2020).

 

  1. TJ Dahle, E Rusten, C Stokkevåg, A Silvoniemi, A Mairani, LF Fjæra, E Rørvik, H Henjum, P Wright, CG Boer, S Forsback, H Minn, E Malinen, KS Ytre-Hauge. The FLUKA Monte Carlo code coupled with an OER model for biologically weighted dose calculations in proton therapy of hypoxic tumors. Phys Med 76, 166-172, doi:10.1016/j.ejmp.2020.07.003 (2020).

 

  1. Lars Fredrik Fjæra1, Daniel J. Indelicato, Camilla H. Stokkevåg, Ludvig P. Muren, Wen C. Hsi, Kristian S. Ytre-Hauge. Implementation of a double scattering nozzle for Monte Carlo recalculation of proton plans with variable relative biological effectiveness. Phys Med Biol, doi:10.1088/1361-6560/abc12d (2020).

 

  1. Ole Marius Otterlei, Daniel J Indelicato, Laura Toussaint, Kristian S. Ytre-Hauge, Sara Pilskog, Lars Fredrik Fjæra, Eivind Rørvik, Helge E S Pettersen, Ludvig P Muren, Yasmin Lassen-Ramshad, Marcos Di Pinto, Camilla H Stokkevåg. Variation in relative biological effectiveness for cognitive structures in proton therapy of pediatric brain tumors. Acta Oncol, 1-8, doi:10.1080/0284186X.2020.1840626 (2020).

 

  1. Lars Fredrik Fjæra, Daniel J. Indelicato, Kristian S. Ytre-Hauge, Zuofeng Li, Ludvig P. Muren, Yasmin Lassen-Ramshad, Laura Toussaint, Stella Flampouri, Olav Dahl, Camilla H. Stokkevåg. Spatial Agreement of Brainstem Dose Distributions Depending on Biological Model in Proton Therapy for Pediatric Brain Tumors. Adv Radiat Oncol 6, 100551, doi:10.1016/j.adro.2020.08.008 (2021).

 

  1. Henjum, H….., Kristian S. Ytre-Hauge et al. The organ sparing potential of different biological optimization strategies in proton therapy. Advances in Radiation Oncology, doi:10.1016/j.adro.2021.100776 (2021).

 

  1. Fjaera, L. F.,.. Kristian S. Ytre-Hauge  et al. (2022). "A case-control study of linear energy transfer and relative biological effectiveness related to symptomatic brainstem toxicity following pediatric proton therapy." Radiother Oncol 175: 47-55. https://doi.org/10.1016/j.radonc.2022.07.022

 

  1. C. Davidsen, K. Bolstad, K. Ytre-Hauge, A. T. Samnøy, K. Vikenes and V. Tuseth. Effect of an optimized X-ray blanket design on operator radiation dose in cardiac catheterization based on real-world angiography. Plos One 2022 Vol. 17 Issue 11 DOI: https://doi.org/10.1371/journal.pone.0277436

 

  1. G. Garrido-Hernandez, H. Henjum, M. K. Hoiskar, T. J. Dahle, K. R. Redalen and K. S. Ytre-Hauge. Hypoxia adapted relative biological effectiveness models for proton therapy: a simulation study Biomed Phys Eng Express 2022 Vol. 8 Issue 6. DOI: https://doi.org/10.1088/2057-1976/ac9b5d

 

  1. Meric, I., Alagoz, E., Hysing, L. B., Kögler, T., Lathouwers, D., Lionheart, W. R., ... & Ytre-Hauge K. (2023). A hybrid multi-particle approach to range assessment-based treatment verification in particle therapy. Scientific Reports, 13(1), 6709. https://doi.org/10.1038/s41598-023-33777-w

 

  1. Henjum, H., Dahle, T. J., Mairani, A., Pilskog, S., Stokkevåg, C., Boer, C. G., ... & Ytre‐Hauge, K. S. (2023). Combined RBE and OER optimization in proton therapy with FLUKA based on EF5‐PET. Journal of Applied Clinical Medical Physics, e14014. https://doi.org/10.1002/acm2.14014

 

  1. Tjelta, J., Fjæra, L. F., Ytre-Hauge, K. S., Boer, C. G., & Stokkevåg, C. H. (2023). A systematic approach for calibrating a Monte Carlo code to a treatment planning system for obtaining dose, LET, variable proton RBE and out-of-field dose. Physics in Medicine & Biology, 68(22), 225010. DOI: 10.1088/1361-6560/ad0281

 

  1. Henjum, H., Tjelta, J., Fjæra, L. F., Pilskog, S., Stokkevåg, C. H., Lyngholm, E., ... & Ytre-Hauge, K. S. (2023). Influence of beam pruning techniques on LET and RBE in proton arc therapy. Frontiers in Oncology, 13, 1155310. https://doi.org/10.3389/fonc.2023.1155310

 

  1. Handeland, A. H., Indelicato, D. J., Fjæra, L. F., Ytre-Hauge, K. S., Pettersen, H. E. S., Muren, L. P., ... & Stokkevåg, C. H. (2023). Linear energy transfer-inclusive models of brainstem necrosis following proton therapy of paediatric ependymoma. Physics and Imaging in Radiation Oncology, 27, 100466. https://doi.org/10.1016/j.phro.2023.100466

 

  1. Handeland AH, Lægdsmand PM, Toussaint L, Stokkevåg CH, Lassen-Ramshad YA, Klitgaard R, Henjum H, Ytre-Hauge KS, Indelicato DJ, Tjelta J, Lyngholm E. & Muren LP Linear energy transfer-inclusive brainstem necrosis risk models applied to an independent paediatric proton therapy cohort. Acta Oncologica. 2023 Sep 6:1-5. https://doi.org/10.1080/0284186X.2023.2254476

 

  1. Tjelta, J., Ytre-Hauge, K., Lyngholm, E., Handeland, A., Henjum, H., & Stokkevåg, C. (2023). Dose exposure to an adult present in the treatment room during pediatric pencil beam scanning proton therapy. Acta Oncologica, 1-5. https://doi.org/10.1080/0284186X.2023.2254924

 

  1. Davidsen, C., Ytre-Hauge, K., Samnøy, A. T., Vikenes, K., Lancellotti, P., & Tuseth, V. (2023). Efficacy and User Experience of a Novel X-Ray Shield on Operator Radiation Exposure During Cardiac Catheterization: A Randomized Controlled Trial. Circulation: Cardiovascular Interventions, e013199. https://doi.org/10.1161/CIRCINTERVENTIONS.123.013199

 

  1. Skjerdal K, Kögler T, Lionheart W, Ytre-Hauge KS, Meric I. (2023). "Prompt gamma-ray spectroscopy in conjunction with the Monte Carlo Library Least Squares approach: Applications to range verification in proton therapy." EPJ Web of Conferences 288. https://doi.org/10.1051/epjconf/202328809003