Neuro-SysMed-seminar – NAD Augmentation as a Disease Modifying Strategy for Neurological Diseases
Velkommen til Neuro-SysMeds månedlige seminarer! Denne gangen vil tema være "NAD Augmentation as a Disease Modifying Strategy for Neurological Diseases." Bli med i auditoriet i Armauer Hansens Hus kl. 11:30–13:00 (lunsj kl. 11:30–12:00).
Hovedinnhold
(Engelsk tekst videre siden seminarene er internasjonale og undervisningsspråket på seminarene er engelsk.)
Title: NAD Augmentation as a Disease Modifying Strategy for Neurological Diseases
Speaker: Charalampos Tzoulis and Christian Dölle
Place: The auditorium in Armauer Hansens Hus (campus Haukeland University Hospital, Bergen)
Time: Wednesday, June 4, 2025, at 11:30–13:00 (lunch 11:30–12:00).
Registration: Please register through this link
Langage: English
Abstract: Neurodegenerative diseases pose a significant and rapidly growing global health challenge. Yet, there are still no effective therapies capable of delaying or halting their progression. In recent years, augmentation of nicotinamide adenine dinucleotide (NAD) has emerged as a promising disease-modifying strategy that targets multiple key disease pathways across multiple neurodegenerative diseases, such as mitochondrial dysfunction, energy deficits, proteostasis, and neuroinflammation. Several early clinical trials of NAD augmentation have been completed, and many more are currently underway, reflecting the growing optimism and urgency within the field. We will discuss the rationale and evolving therapeutic landscape of NAD augmentation. We will argue that to fully realize its therapeutic potential, it is essential to determine the specific contexts in which NAD supplementation is most effective and to address crucial knowledge gaps.
More reading: See the recent publication NAD augmentation as a disease-modifying strategy for neurodegeneration by Christian Dölle and Charalampos Tzoulis.