Infeksjon og mikrobiologi


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Low-cost point-of care cryptosporidiosis test in children in Ethiopia (CRYPTO-POC)


The primary objective of this study is to estimate the accuracy and operational performance of simple microscopy of auramine stained stool samples for diagnosis of Cryptosporidium infection. Secondary aims are to evaluate risk factors for Cryptosporidium infection and shedding over time. 1500 Ethiopian children below 5 years presenting to a Teaching Hospital or Health center with diarrhea over a 12-month enrollment period will be included. Additionally 750 healthy controls from health centers in the same area will be included. Clinical data, HIV test and a stool sample will be collected and analyzed. The main outcome of the study is improved diagnosis of cryptosporidiosis in resource limited settings.