The overall strategy is the exploitation of novel methods for assessment of biomarker status based on mass spectrometry to carry out metabolic profiling of large national and international cohorts. These include the Hordaland health studies, HUSK, EPIC, NORCCAP, WENBIT, NORVIT, JANUS, MoBa and the multi-center study One-carbon metabolism biomarkers and lung cancer (LC3).
Could it be that some people should stay far away from the dreaded saturated fat , while other people actually should eat more of it ? Is the high intake of omega 3 fatty acids really healthy for everyone, or it may simply be dangerous for certain?
Today we can point out to some extent which people have increased risk of heart attack, for example, for those who smoke or have diabetes. This is important because heart attacks are one of the leading causes of morbidity and mortality worldwide. Still, there are many people who get heart attacks without having such traditional risk factors, and the chances of recurrence is high, despite optimal treatments and lifestyle changes.
Although lifestyle advices and treatments have probably improved the prognosis of myocardial infarction in general, it does not equally be good for all. We believe that, to a great extent, adjusted treatments and preventive measures based on individual biological assumptions that each person has is very important and precise because we as humans react differently.
Our research group asks the question : Can it be so simple that blood and urine tests are informative enough to draw clinical advices about lifestyle improvement or treatments to decrease the risk of heart attack?