Institutt for biomedisin


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BBB Seminar: Ole A. Andreassen

Breakthrough in schizophrenia genetics – implications for disease mechanisms?

Ole A. Andreassen,
Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo

The disease mechanisms of schizophrenia remain a major enigma. Recent genome-wide association studies have lead to the finding of both common DNA variants of single-nucleotide polymorphisms (SNPs) and rare genetic copy-number variants (CNVs) associated with schizophrenia. With increasing sample sizes more markers are being discovered. The potential implications of these results for the pathophysiology of schizophrenia will be discussed.

Host: Jan Haavik, Department of Biomedicine