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Alf Inge Larsens bilde

Alf Inge Larsen

Professor
  • E-postAlf.Larsen@uib.no
  • Telefon+47 51 51 80 00
  • Besøksadresse
    Haukeland universitetssykehus, Laboratoriebygget
    5009 Bergen
  • Postadresse
    Postboks 7804
    5020 Bergen
Vitenskapelig artikkel
  • Vis forfatter(e) (2021). Rationale and design of the PRevention of cArdiac Dysfunction during Adjuvant breast cancer therapy (PRADA II) trial: a randomized, placebo-controlled, multicenter trial. Cardio-Oncology. 11 sider.
  • Vis forfatter(e) (2021). Identification of vulnerable plaques and patients by intracoronary near-infrared spectroscopy and ultrasound (PROSPECT II): a prospective natural history study. The Lancet. 985-995.
  • Vis forfatter(e) (2021). Exercise training and high-sensitivity cardiac troponin T in patients with heart failure with reduced ejection fraction. ESC Heart Failure. 2183-2192.
  • Vis forfatter(e) (2021). Burden of treatment in patients with chronic heart failure – A cross-sectional study. Heart & Lung. 369-374.
  • Vis forfatter(e) (2021). Blood Lactate AUC Is a Sensitive Test for Evaluating the Effect of Exercise Training on Functional Work Capacity in Patients with Chronic Heart Failure. Rehabilitation Research and Practice. 1-6.
  • Vis forfatter(e) (2020). Worst lead ST deviation and resolution of ST elevation at one hour for prediction of myocardial salvage, infarct size, and microvascular obstruction in patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention. Annals of Noninvasive Electrocardiology.
  • Vis forfatter(e) (2020). Rethinking rehabilitation after percutaneous coronary intervention: a protocol of a multicentre cohort study on continuity of care, health literacy, adherence and costs at all care levels (the CONCARDPCI). BMJ Open. e031995.
  • Vis forfatter(e) (2020). Pentraxin 3 in primary percutaneous coronary intervention for ST elevation myocardial infarction is associated with early irreversible myocardial damage: Kinetic profile, relationship to interleukin 6 and infarct size. European Heart Journal: Acute Cardiovascular Care. 302-312.
  • Vis forfatter(e) (2020). Increased functional capacity after 12 weeks of exercise training does not transform into improved skeletal muscle metabolism or ultrastructure in heart failure patients on modern optimal medical therapy. European Journal of Preventive Cardiology (EJPC). 1-7.
  • Vis forfatter(e) (2020). Exploration of plasma lipids in mild cognitive impairment due to Alzheimer's disease . Journal of Alzheimer's Disease. 1117-1127.
  • Vis forfatter(e) (2020). Effects of purified anthocyanins in people at risk for dementia: Study protocol for a phase II randomized controlled trial. Frontiers in Neurology. 1-10.
  • Vis forfatter(e) (2020). Cardiac arrest as a reportable condition: A cohort study of the first 6 years of the Norwegian out-of-hospital cardiac arrest registry. BMJ Open. 1-7.
  • Vis forfatter(e) (2019). Plasma tumour necrosis factor correlates with mRNA expression of tumour necrosis factor and mitochondrial transcription factors in skeletal muscle in patients with chronic heart failure treated with cardiac resynchronization therapy: potential role in myopathy. European Journal of Preventive Cardiology (EJPC). 1-5.
  • Vis forfatter(e) (2019). Effects of interval training on inflammatory biomarkers in patients with ischemic heart failure. Scandinavian Cardiovascular Journal. 213-219.
  • Vis forfatter(e) (2019). Effects of anthocyanin supplementation on serum lipids, glucose, markers of inflammation and cognition in adults with increased risk of dementia - A pilot study. Frontiers in Genetics. 1-11.
  • Vis forfatter(e) (2019). Baseline and Exercise Predictors of VO2peak in Systolic Heart Failure Patients: Results from SMARTEX-HF. Medicine & Science in Sports & Exercise. 810-819.
  • Vis forfatter(e) (2019). BEtablocker Treatment After acute Myocardial Infarction in revascularized patients without reduced left ventricular ejection fraction (BETAMI): Rationale and design of a prospective, randomized, open, blinded end-point study. American Heart Journal. 37-46.
  • Vis forfatter(e) (2019). Automatic estimation of coronary blood flow velocity step 1 for developing a tool to diagnose patients with micro-vascular angina pectoris. Frontiers in Cardiovascular Medicine. 1-11.
  • Vis forfatter(e) (2018). The significance of ST-elevation in aVL in anterolateral myocardial infarction: An assessment by cardiac magnetic resonance imaging. Annals of Noninvasive Electrocardiology. 1-7.
  • Vis forfatter(e) (2018). Electrocardiographic scores of severity and acuteness of myocardial ischemia predict myocardial salvage in patients with anterior ST-segment elevation myocardial infarction. Journal of Electrocardiology. 195-202.
  • Vis forfatter(e) (2018). Correlation of anteroseptal ST elevation with myocardial infarction territories through cardiovascular magnetic resonance imaging. Journal of Electrocardiology. 563-568.
  • Vis forfatter(e) (2017). Targeted temperature management for 48 vs 24 hours and neurologic outcome after out-of-hospital cardiac arrest: A randomized clinical trial. Journal of the American Medical Association (JAMA). 341-350.
  • Vis forfatter(e) (2017). Intracoronary autologous bone marrow cell transfer after myocardial infarction: The BOOST-2 randomised placebo-controlled clinical trial. European Heart Journal. 2936-2943.
  • Vis forfatter(e) (2017). Impact of an exercise training program on cardiac neuronal function in heart failure patients on optimal medical therapy: A randomized Iodine-123 metaiodobenzylguanidine scintigraphy study. Journal of Nuclear Cardiology. 1-8.
  • Vis forfatter(e) (2017). High-Intensity Interval Training in Patients with Heart Failure with Reduced Ejection Fraction. Circulation. 839-849.
  • Vis forfatter(e) (2017). Appropriateness of anteroseptal myocardial infarction nomenclature evaluated by late gadolinium enhancement cardiovascular magnetic resonance imaging. Journal of Electrocardiology. 218-223.
  • Vis forfatter(e) (2017). Administration of the Mitochondrial Permeability Transition Pore Inhibitor, TRO40303, prior to Primary Percutaneous Coronary Intervention, Does Not Affect the Levels of Pro-Inflammatory Cytokines or Acute-Phase Proteins. Cardiology. 122-132.
  • Vis forfatter(e) (2016). Time-differentiated target temperature management after out-of-hospital cardiac arrest: A multicentre, randomised, parallel-group, assessor-blinded clinical trial (the TTH48 trial): Study protocol for a randomised controlled trial. Trials. 9 sider.
  • Vis forfatter(e) (2016). Effects of aerobic interval training on measures of anxiety, depression and quality of life in patients with ischaemic heart failure and an implantable cardioverter defibrillator: A prospective non-randomized trial. Journal of Rehabilitation Medicine. 300-306.
  • Vis forfatter(e) (2016). Effect of Vascular Risk Factors on the Progression of Mild Alzheimer's Disease and Lewy Body Dementia. Journal of Alzheimer's Disease. 575-584.
  • Vis forfatter(e) (2016). Drug-Eluting or Bare-Metal Stents for Coronary Artery Disease . New England Journal of Medicine. 1242-1252.
  • Vis forfatter(e) (2016). Confronting one's vulnerability - patients with chest pain participating in a high-intensity exercise programme. Journal of Clinical Nursing (JCN). 2006-2015.
  • Vis forfatter(e) (2016). A statistical analysis protocol for the time-differentiated target temperature management after out-of-hospital cardiac arrest (TTH48) clinical trial. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 1-8.
  • Vis forfatter(e) (2015). The Localization and Characterization of Ischemic Scars in relation to the Infarct Related Coronary Artery Assessed by Cardiac Magnetic Resonance and a Novel Automatic Postprocessing Method. Cardiology Research and Practice. 9 sider.
  • Vis forfatter(e) (2015). Effect of intravenous TRO40303 as an adjunct to primary percutaneous coronary intervention for acute ST-elevation myocardial infarction: MITOCARE study results. European Heart Journal. 112-119.
  • Vis forfatter(e) (2015). Aerobic interval training in patients with heart failure and an implantable cardioverter defibrillator: a controlled study evaluating feasibility and effect. European Journal of Preventive Cardiology (EJPC). 296-303.
  • Vis forfatter(e) (2014). Perceptions of healthcare professionals' support, shock anxiety and device acceptance among implantable cardioverter defibrillator recipients. Journal of Advanced Nursing. 2061-2071.
  • Vis forfatter(e) (2014). Perceived support from healthcare professionals, shock anxiety and post-traumatic stress in implantable cardioverter defibrillator recipients. Journal of Clinical Nursing (JCN). 450-460.
  • Vis forfatter(e) (2014). Comparison of Outcomes in Patients with ST-Segment Elevation Myocardial Infarction Discharged on Versus Not on Statin Therapy (from the Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction Trial). American Journal of Cardiology. 1273-1279.
  • Vis forfatter(e) (2013). Long-term prognosis of patients presenting with ST-segment elevation myocardial infarction with no significant coronary artery disease (from The HORIZONS-AMI Trial). American Journal of Cardiology. 643-648.
  • Vis forfatter(e) (2013). Factors predicting the use of therapeutic hypothermia and survival in unconscious out-of-hospital cardiac arrest patients admitted to the ICU. Critical Care. 10 sider.
  • Vis forfatter(e) (2013). Cardiac resynchronization therapy improves minute ventilation/carbon dioxide production slope and skeletal muscle capillary density without reversal of skeletal muscle pathology or inflammation. Europace. 857-864.
  • Vis forfatter(e) (2012). Shock anxiety among implantable cardioverter defibrillator recipients with recent tachyarrhythmia. Pacing and Clinical Electrophysiology. 1369-1376.
  • Vis forfatter(e) (2012). Rationale and Design of the 'MITOCARE' Study: A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of TRO40303 for the Reduction of Reperfusion Injury in Patients Undergoing Percutaneous Coronary Intervention for Acute Myocardial Infarction. Cardiology. 201-207.
  • Vis forfatter(e) (2012). Increased confidence to engage in physical exertion: older ICD recipients' experiences of participating in an exercise training programme. European Journal of Cardiovascular Nursing. 261-268.
  • Vis forfatter(e) (2011). Response of growth differentiation factor-15 to percutaneous coronary intervention and regular exercise training. Scandinavian Cardiovascular Journal. 27-32.
  • Vis forfatter(e) (2011). Inflammatory response to percutaneous coronary intervention in stable coronary artery disease. Journal of Thrombosis and Thrombolysis. 92-98.
  • Vis forfatter(e) (2011). High intensity interval training reduces systemic inflammation in post-PCI patients. European Journal of Cardiovascular Prevention & Rehabilitation. 850-857.
  • Vis forfatter(e) (2011). Endothelial dysfunction predicts clinical restenosis after percutaneous coronary intervention. Scandinavian Cardiovascular Journal. 139-145.
  • Vis forfatter(e) (2010). Variations in population-based levels of C-reactive protein, cardiovascular morbidity and all-cause mortalitystar, open: An analysis of the relationship between C-reactive protein, Troponin-T, cardiovascular morbidity and death rates in an unselected population in Southwest Norway. International Journal of Cardiology. 247-249.
  • Vis forfatter(e) (2010). The activity of pregnancy-associated plasma protein A (PAPP-A) as expressed by immunohistochemistry in atherothrombotic plaques obtained by aspiration thrombectomy in patients presenting with a ST-elevation myocardial infarction: a brief communication. Thrombosis Journal.
  • Vis forfatter(e) (2010). Reversible fetal renal failure after maternal treatment with Candesartan: A case report. Reproductive Toxicology. 381-382.
  • Vis forfatter(e) (2010). Coronary blood flow and perfusion pressure during coronary angiography in patients with ongoing mechanical chest compression: a report on 6 cases. Resuscitation. 493-497.
  • Vis forfatter(e) (2010). A history of late and very late stent thrombosis is not associated with increased activation of the contact system, a case control study. Thrombosis Journal. 6.
  • Vis forfatter(e) (2009). Microvascular obstruction is a major determinant of infarct healing and subsequent left ventricular remodelling following primary percutaneous coronary intervention. European Heart Journal. 1978-1985.
  • Vis forfatter(e) (2009). High-intensity interval training may reduce in-stent restenosis following percutaneous coronary intervention with stent implantation: A randomized controlled trial evaluating the relationship to endothelial function and inflammation. American Heart Journal. 734-741.
  • Vis forfatter(e) (2009). B-type natriuretic peptide is related to histological skeletal muscle abnormalities in patients with chronic heart failure. International Journal of Cardiology. 358-362.
  • Vis forfatter(e) (2009). B-type natriuretic peptide is related to histological skeletal muscle abnormalities in patients with chronic heart failure. International Journal of Cardiology. 358-362.
  • Vis forfatter(e) (2008). Effect of exercise training on chromogranin A and relationship to N-ANP and inflammatory cytokines in patients with chronic heart failure. International Journal of Cardiology. 117-120.
  • Vis forfatter(e) (2008). Effect of exercise training on chromogranin A and relationship to N-ANP and inflammatory cytokines in patients with chronic heart failure. International Journal of Cardiology. 117-120.
  • Vis forfatter(e) (2008). Change to a primary PCI program increases number of patients offered reperfusion therapy and significantly reduces mortality. A real life experience evaluating the initiation of a primary PCI service at a single center without on site heart surgery in Western Norway. International Journal of Cardiology. 208-213.
  • Vis forfatter(e) (2007). Trening etter perkutan koronar intervensjon en undervurdert behandlingsmulighet. Tidsskrift for Den norske legeforening. 1365-1367.
  • Vis forfatter(e) (2007). Cardiac arrest with continuous mechanical chest compression during percutaneous coronary intervention A report on the use of the LUCAS device. Resuscitation. 454-459.
  • Vis forfatter(e) (2007). Anomalies of the coronary arteries originating from the right sinus of Valsalva (1) Single coronary artery originating from the right sinus associated with fusion of the left and the non coronary cusp and atrophy of the left coronary ostium (2)Three separate coronary arteries originating from the right sinus of Valsalva. International Journal of Cardiology. e86-e89.
  • Vis forfatter(e) (2006). The effect of altering haemodynamics on the plasma concentrations of natriuretic peptides in heart failure. European Journal of Heart Failure. 628-633.
  • Vis forfatter(e) (2006). The effect of altering haemodynamics on the plasma concentrations of natriuretic peptides in heart failure. European Journal of Heart Failure. 628-633.
  • Vis forfatter(e) (2006). Nonemergent coronary angioplasty without on-site surgical backup: A randomized study evaluating outcomes in low-risk patients. American Heart Journal. 888-895.
  • Vis forfatter(e) (2006). Late complications following the deployment of drug eluting stents. International Journal of Cardiology. 398-401.
  • Vis forfatter(e) (2006). Large and small vessel vasoconstriction following coronary artery stenting - Effect of intra coronary nitroglycerine and relation to LDL cholesterol. International Journal of Cardiology. 61-65.
  • Vis forfatter(e) (2005). Persistent left superior vena cava. Use of an innominate vein between left and right superior caval veins for the placement of a right ventricular lead during ICD/CRT implantation. European Heart Journal. 2178.
  • Vis forfatter(e) (2005). Exercise training in congestive heart failure. A review of the current status. Minerva Cardioangiologica : a Journal on Cardiovascular Pathophysiology, Clinical Medicine and Therapy. 275-286.
  • Vis forfatter(e) (2005). Characteristics and outcomes of patients with acute myocardial infarction and angiographically normal coronary arteries. American Journal of Cardiology. 261-263.
  • Vis forfatter(e) (2004). Effect of exercise training in patients with heart failure: a pilot study on autonomous balance assessed by heart rate variability. Journal of Cardiovascular Risk. 162-167.
  • Vis forfatter(e) (2004). Effect of exercise training in patients with heart failure: a pilot study on autonomic balance assessed by heart rate variability. Journal of Cardiovascular Risk. 162-167.
  • Vis forfatter(e) (2003). Prognostic usefulness of an increase of N-terminal proatrial natriuretic peptide during exercise in patients with chronic heart failure. American Journal of Cardiology. 91-94.
  • Vis forfatter(e) (1996). Pro-atrial natriuretisk faktor i plasma er prediktiv for klinisk status hos hjertesviktpasienter. Tidsskrift for Den norske legeforening. 1562-1566.
Faglig foredrag
  • Vis forfatter(e) (2017). SEGMENTATION OF CORONARY ARTERIES FROM X-RAY ANGIOGRAPHY SEQUENCES DURING CONTRAST FLUID PROPAGATION BY IMAGE REGISTRATION.
Vitenskapelig foredrag
  • Vis forfatter(e) (2016). A computer model for non-invasive heart diagnostics.
  • Vis forfatter(e) (2014). Making sense of participating in an exercise training programme for chest pain patients with unexplained chest pain.
Leder
  • Vis forfatter(e) (2020). The pulse; from adagio to prestissimo; the prognostic importance of heart rate increase and its associations with cardiovascular risk factors. European Journal of Preventive Cardiology (EJPC). 520-525.
  • Vis forfatter(e) (2018). The muscle hypothesis in heart failure revised: ‘The multisite training approach’. European Journal of Preventive Cardiology (EJPC). 1252-1256.
  • Vis forfatter(e) (2017). Strength and aerobic exercise training in coronary artery disease; it's not `either-or? European Journal of Preventive Cardiology (EJPC). 1686-1691.
  • Vis forfatter(e) (2012). Clinical and biomarker profile of trauma-induced secondary cardiac injury (Br J Surg 2012; 99: 789-797). British Journal of Surgery. 797-798.
Leserinnlegg
  • Vis forfatter(e) (2016). Ut samme dag etter perkutan koronar intervensjon. Tidsskrift for Den norske legeforening. 384-385.
  • Vis forfatter(e) (2012). Symptoms of anxiety and depression after percutaneous coronary intervention are associated with decreased heart rate variability, impaired endothelial function and increased inflammation. International Journal of Cardiology. 173-176.
  • Vis forfatter(e) (2010). High-intensity interval exercise training improves heart rate variability in patients following percutaneous coronary intervention for angina pectoris. International Journal of Cardiology. 312-314.
Brev til redaktøren
  • Vis forfatter(e) (2008). B-type natriuretic peptide is related to histological skeletal muscle abnormalities in patients with chronic heart failure. International Journal of Cardiology.
  • Vis forfatter(e) (2004). Can sedentary patients with heart failure achieve the beneficial effect of exercise training without moving? European Heart Journal. 104-106.
  • Vis forfatter(e) (2004). BNP in acute coronary syndromes: the heart expresses its suffering. European Heart Journal. 1284-1286.
Doktorgradsavhandling
  • Vis forfatter(e) (2016). Exercise training in patients with heart failure and an implantable cardioverter defibrillator. Review of existing data, shock anxiety, feasibility and effects of an aerobic interval training intervention.
  • Vis forfatter(e) (2004). Exercise training in congestive heart failure: evaluation of test protocols and effect on neurohormones, cytokines, heart rate variability and skeletal muscle histology.
Intervju
  • Vis forfatter(e) (2018). Vil bruke oljeteknologi - på hjertepasienter.
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
  • Vis forfatter(e) (2017). SEGMENTATION OF CORONARY ARTERIES FROM X-RAY ANGIOGRAPHY SEQUENCES DURING CONTRAST FLUID PROPAGATION BY IMAGE REGISTRATION.
Sammendrag/abstract
  • Vis forfatter(e) (2021). Perceptions of efficacy and safety of generic medicines in patients after percutaneous coronary intervention. European Heart Journal.
  • Vis forfatter(e) (2021). Communication of Potential Adverse Drug Reactions in Patients Undergoing Percutaneous Coronary Intervention. Circulation.
  • Vis forfatter(e) (2020). Estimation of cardiac output from test-bolus during coronary computed tomography angiography: a personalized mathematical model. European Heart Journal. 3454-3454.
  • Vis forfatter(e) (2019). Patients’ Perceptions of Generic Drugs After Percutaneous Coronary Intervention: A Multicentre Cohort Study. Circulation.
  • Vis forfatter(e) (2012). Shock anxiety in ICD recipients: what is the impact of recent tachyarrhythmia - irrespective of shock exposure? European Journal of Cardiovascular Nursing. S10-S10.
  • Vis forfatter(e) (2009). High Intensity Interval Training Reduces Late Luminal Loss Following Percutaneous Coronary Intervention With Stent Implantation. Journal of the American College of Cardiology. A258-A258.
  • Vis forfatter(e) (2006). Calprotectin and S100A12 correlate with disease activity in rheumatoid arthritis, and S100A12 is associated with concomitant cardiovascular disease. Scandinavian Journal of Rheumatology. 40-40.
Poster
  • Vis forfatter(e) (2019). Patients discharged on the same day following elective PCI report equal satisfaction using health related quality of life instruments as compared to usual care: results from a randomized trial. EHJ 2019; 40: Suppl. 1, P6527, ehz746.1117.
  • Vis forfatter(e) (2018). Circulation. 2018;138:A12525. No Effect of Glycoprotein Platelet Inhibitors Administered During Primary PCI in Patients Included in the Norwegian Coronary Stent Trial.
  • Vis forfatter(e) (2013). The relationship between perceived support from healthcare professionals, shock anxiety and device acceptance in implantable cardioverter defibrillator recipients.
  • Vis forfatter(e) (2013). Perceived support from health care professionals, shock anxiety and posttraumatic stress in implantable cardioverter defibrillator recipients.
  • Vis forfatter(e) (2012). Shock Anxiety among Implantable Cardioverter Defibrillator Recipients with Recent Tachyarrhythmia.
  • Vis forfatter(e) (2012). Increased confidence to engage in physical exertion; older recipients’ experiences of participating in an exercise training programme.
  • Vis forfatter(e) (2010). Patients admitted with ST-segment elevation myocardial Infarction and a normal or near normal coronary angiogram have a favorable prognosis: Analysis from HORIZONS-AMI trial. J Am Coll Cardiol 2010;55;A187.E1746 doi:10.1016/S0735-1097(10)61747-0.
  • Vis forfatter(e) (2009). A history of late stent thrombosis is not associated with increased activation of the contact phase system. Journal of Thrombosis and Haemostasis 2009; Volume 7, Supplement 2: Abstract PP-MO-433.
  • Vis forfatter(e) (2006). Primary PCI vs thrombolysis:An analysis of differences in outcome in a single centre without on site heart surgery in South-West Norway. Eur Heart J 2006, 27(Abstract Suppl), 315.
  • Vis forfatter(e) (2006). Non-emergent coronary angioplasty without on-site surgical back-up: A randomized study evaluating outcomes in low-risk patients. Eur Heart J 2006, 27(Abstract Suppl), 517.
Errata
  • Vis forfatter(e) (2021). Corrigendum: Effects of Anthocyanin Supplementation on Serum Lipids, Glucose, Markers of Inflammation and Cognition in Adults With Increased Risk of Dementia – A Pilot Study (Front. Genet., (2019), 10, (536), 10.3389/fgene.2019.00536). Frontiers in Genetics.
Vitenskapelig oversiktsartikkel/review
  • Vis forfatter(e) (2021). Aortic calcification; from innocent bystander to independent predictor; the delicate balance in biology; da aaaCapo: Editorial accompanying 'Abdominal aortic calcification - from ancient friend to modern foe'. European Journal of Preventive Cardiology (EJPC). E20-E24.
  • Vis forfatter(e) (2013). Is it safe to use TNF-α blockers for systemic inflammatory disease in patients with heart failure? Importance of dosage and receptor specificity. International Journal of Cardiology. 1719-1723.
  • Vis forfatter(e) (2012). Exercise training and cardiac rehabilitation in patients with implantable cardioverter defibrillators: a review of current literature focusing on safety, effects of exercise training, and the psychological impact of programme participation. European Journal of Preventive Cardiology (EJPC). 804-812.
Fagartikkel
  • Vis forfatter(e) (2016). Kan pasienten skrives ut samme dag etter elektiv Percutan Koronar Intervensjon? Hjerteposten : fagtidsskrift for NSFs landsgruppe av kardiologiske sykepleiere.
  • Vis forfatter(e) (2014). Kardial resynkroniseringsterapi ved hjertesvikt – norske retningslinjer. Tidsskrift for Den norske legeforening. E1-17.

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