- E-postandre.sulen@uib.no
- BesøksadresseHaukeland universitetssykehus, Laboratoriebygget5009 Bergen
- PostadressePostboks 78045020 Bergen
I graduated as a PhD from the University of Bergen in 2016. My project evaluated signal transduction in blood leukocytes as biomarkers for environmental stress exerted on the healthy population. During postdoctoral studies at Karolinska Institutet I gained experience with single-cell approaches to study the immune system in metabolic disease. Today I aim to utilize these experiences during studies of autoimmunity, specifically immune mediated adrenal failure, also called Addison´s disease.
Vitenskapelig artikkel
- (2023). A partial form of AIRE deficiency underlies a mild form of autoimmune polyendocrine syndrome type 1. Journal of Clinical Investigation.
- (2021). p53 Protein Isoform Profiles in AML: Correlation with Distinct Differentiation Stages and Response to Epigenetic Differentiation Therapy. Cells. 14 sider.
- (2021). Feminizing adrenal tumor identified by plasma steroid profiling. Endocrinology, Diabetes and Metabolism Case Reports. 1-5.
- (2020). Early Response to the Plant Toxin Stenodactylin in Acute Myeloid Leukemia Cells Involves Inflammatory and Apoptotic Signaling. Frontiers in Pharmacology.
- (2019). Titrating complex mass cytometry panels. Cytometry Part A. 1-6.
- (2019). Modulation of phospho-proteins by interferon-alpha and valproic acid in acute myeloid leukemia. Journal of Cancer Research and Clinical Oncology. 1729-1749.
- (2019). Candidate markers for stratification and classification in rheumatoid arthritis. Frontiers in Immunology. 1-8.
- (2016). Signaling effects of sodium hydrosulfide in healthy donor peripheral blood mononuclear cells. Pharmacological Research. 216-227.
- (2016). Elevated monocyte phosphorylated p38 in nearby employees after a chemical explosion. Scientific Reports.
- (2016). Anti-proliferative activity of the NPM1 interacting natural product avrainvillamide in acute myeloid leukemia. Cell Death & Disease. 1-14.
- (2014). Evaluation of the effects of clinical diagnostic ultrasound in combination with ultrasound contrast agents on cell stress: Single cell analysis of intracellular phospho-signaling pathways in blood cancer cells and normal blood leukocytes. IEEE International Ultrasonics Symposium Proceedings. 1186-1190.
- (2013). Increased antileukemic effects in human acute myeloid leukemia by combining HSP70 and HSP90 inhibitors. Expert Opinion on Investigational Drugs. 551-563.
- (2013). Gel2DE-A software tool for correlation analysis of 2D gel electrophoresis data. BMC Bioinformatics. 5 sider.
- (2013). Expression of TP53 isoforms p53 beta or p53 gamma enhances chemosensitivity in TP53(null) cell lines. PLOS ONE. 11 sider.
- (2013). Distinct single cell signal transduction signatures in leukocyte subsets stimulated with khat extract, amphetamine-like cathinone, cathine or norephedrine. BMC Pharmacology & Toxicology. 13 sider.
- (2012). Leukocyte p53 protein biosignature through standard-aligned two-dimensional immunoblotting. Journal of Proteomics. 69-78.
Anmeldelse
- (2020). Fed Macrophages Hit the Liver's Sweet Spot with IL-10. Molecular Cell. 1-3.
Doktorgradsavhandling
- (2016). Leukocyte p38 and p53 proteins after environmental exposure; variation, associations and applicability.
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
- (2013). Ultrasound combined with microbubbles modulates signal transduction pathways in blood cells. 2 sider.
Poster
- (2017). combination of interferon-alpha and valproic acid in acute myeloid leukemia cells in vitro and in vivo.
Vitenskapelig oversiktsartikkel/review
- (2020). The prospects of single-cell analysis in autoimmunity. Scandinavian Journal of Immunology. 1-15.
- (2014). Heat shock protein 70 - the next chaperone to target in the treatment of human acute myelogenous leukemia? Expert opinion on therapeutic targets. 929-944.
Kompetansefelt