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Bergithe Eikeland Oftedals bilde

Bergithe Eikeland Oftedal

Forsker
  • E-postBergithe.Oftedal@uib.no
  • Besøksadresse
    Haukeland universitetssykehus, Laboratoriebygget
  • Postadresse
    Postboks 7804
    5020 Bergen

Post doc i gruppen Endokrin medisin ledet av Professor Eystein Husebye. Forsker på endokrin autoimmunitet, med spesielt fokus på den monogene autoimmune sykdommen autoimmun polyendokrin svikt type I (APS-I) og genet som forårsaker denne sykdommen, autoimmun regulator (AIRE) genet.

Bøker
  • Oftedal, Bergithe Eikeland. 2019. Thymus transcriptome and Cell biology; Chapter 8. Springer. 300 sider. ISBN: 978-3-030-12039-9.
Tidsskriftartikler
  • Berglund, Agnethe; Cleemann, Line; Oftedal, Bergithe Eikeland; Holm, Kirsten; Husebye, Eystein Sverre; Gravholt, Claus H. 2018. 21-hydroxylase autoantibodies are more prevalent in Turner syndrome but without an association to the autoimmune polyendocrine syndrome type I. Clinical and Experimental Immunology. 1-5. doi: 10.1111/cei.13231
  • Bruserud, Øyvind; Siddiqui, Huma; Cuida Marthinussen, Ileana Mihaela; Chen, Tsute; Jonsson, Roland; Oftedal, Bergithe Eikeland; Olsen, Ingar; Husebye, Eystein Sverre; Wolff, Anette Susanne Bøe. 2018. Oral microbiota in autoimmune polyendocrine syndrome type 1. Journal of Oral Microbiology. 10:1442986: 1-10. doi: 10.1080/20002297.2018.1442986
  • Bruserud, Øyvind; Bratland, Eirik; Hellesen, Alexander; Delaleu, Nicolas; Reikvam, Håkon; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe. 2017. Altered immune activation and IL-23 signaling in response to Candida albicans in autoimmune polyendocrine syndrome type 1. Frontiers in Immunology. 8:1074: 1-10. doi: 10.3389/fimmu.2017.01074
  • Oftedal, Bergithe Eikeland; Ardesjo Lundgren, Brita; Hamm, David; Gan, Poh-Yi; Holdsworth, Stephen R; Hahn, Christopher N.; Schreiber, Andreas W.; Scott, Hamish S. 2017. T cell receptor assessment in autoimmune disease requires access to the most adjacent immunologically active organ. Journal of Autoimmunity. 81: 24-33. doi: 10.1016/j.jaut.2017.03.002
  • Oftedal, Bergithe Eikeland; Cuida Marthinussen, Ileana Mihaela; Erichsen, Martina Moter; Tveitarås, Maria Kathrine; Kjellesvik-Kristiansen, Anja; Hammenfors, Daniel; Jonsson, Malin V; Kisand, Kai; Jonsson, Roland; Wolff, Anette Susanne Bøe. 2017. Impaired salivary gland activity in patients with autoimmune polyendocrine syndrome type I. Autoimmunity. 50: 211-222. doi: 10.1080/08916934.2017.1344972
  • Orlova, Elizaveta M.; Sozaeva, Leila S.; Kareva, Maria A.; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Breivik, Lars Ertesvåg; Zakharova, Ekaterina Y.; Ivanova, Olga N.; Kämpe, Olle; Dedov, Ivan I.; Knappskog, Per; Peterkova, Valentina A.; Husebye, Eystein Sverre. 2017. Expanding the Phenotypic and Genotypic Landscape of Autoimmune Polyendocrine Syndrome Type 1. Journal of Pediatric Endocrinology & Metabolism (JPEM). 102: 3546-3556. doi: 10.1210/jc.2017-00139
  • Bruserud, Øyvind; Oftedal, Bergithe Eikeland; Landegren, Nils; Erichsen, Martina Moter; Bratland, Eirik; Lima, Kari; Jørgensen, Anders Palmstrøm; Myhre, Anne Grethe; Svartberg, Johan; Fougner, Kristian J; Bakke, Åsne; Nedrebø, Bjørn Gunnar; Mella, Bjarne; Breivik, Lars Ertesvåg; Viken, Marte K; Knappskog, Per; Cuida Marthinussen, Ileana Mihaela; Løvås, Kristian; Kämpe, Olle; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre. 2016. A longitudinal follow-up of autoimmune polyendocrine syndrome type 1. Journal of Clinical Endocrinology and Metabolism. 101: 2975-2983. doi: 10.1210/jc.2016-1821
  • Bruserud, Øyvind; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre. 2016. AIRE-mutations and autoimmune disease. Current Opinion in Immunology. 43: 8-15. doi: 10.1016/j.coi.2016.07.003
  • Pazderska, Agnieszka; Oftedal, Bergithe Eikeland; Napier, Catherine M.; Ainsworth, Holly F.; Husebye, Eystein Sverre; Cordell, Heather J.; Pearce, Simon H.S.; Mitchell, Anna L. 2016. A variant in the BACH2 gene is associated with susceptibility to autoimmune addison's disease in humans. Journal of Clinical Endocrinology and Metabolism. 101: 3865-3869. doi: 10.1210/jc.2016-2368
  • Hu, Zhiqiang; Scott, Hamish S.; Qin, Guangrong; Zheng, Guangyong; Chu, Xixia; Xie, Lu; Adelson, David L.; Oftedal, Bergithe Eikeland; Venugopal, Parvathy; Babic, Milena; Hahn, Christopher N.; Zhang, Bing; Wang, Xiaojing; Li, Nan; Wei, Chaochun. 2015. Revealing missing human protein isoforms based on Ab initio prediction, RNA-seq and proteomics. Scientific Reports. 5:10940. doi: 10.1038/srep10940
  • Mordaunt, Dylan; Oftedal, Bergithe Eikeland; McLauchlan, Alisha; Coates, Danika; Waters, Wendy; Scott, Hamish; Barnett, Christopher. 2015. 8q13.1-q13.2 deletion associated with inferior cerebellar vermian hypoplasia and digital anomalies: A new syndrome? Pediatric Neurology. 52: 230-234.e1. doi: 10.1016/j.pediatrneurol.2014.09.002
  • Oftedal, Bergithe Eikeland; Hellesen, Alexander; Erichsen, Martina Moter; Bratland, Eirik; Vardi, Ayelet; Perheentupa, Jaakko; Kemp, E. Helen; Fiskerstrand, Torunn; Viken, Marte K; Weetman, Anthony P.; Fleishman, Sarel J.; Banka, Siddharth; Newman, William G.; Sewell, William A. Carrock; Sozaeva, Leila S.; Zayats, Tetyana; Haugarvoll, Kristoffer; Orlova, Elizaveta M.; Haavik, Jan; Johansson, Stefan; Knappskog, Per; Løvås, Kristian; Wolff, Anette Susanne Bøe; Abramson, Jakub; Husebye, Eystein Sverre. 2015. Dominant mutations in the autoimmune regulator AIRE are associated with common organ-specific autoimmune diseases. Immunity. 42: 1185-1196. doi: 10.1016/j.immuni.2015.04.021
  • Breivik, Lars Ertesvåg; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Bratland, Eirik; Orlova, Elizaveta M.; Husebye, Eystein Sverre. 2014. A novel cell-based assay for measuring neutralizing autoantibodies against type I interferons in patients with autoimmune polyendocrine syndrome type 1. Clinical Immunology. 153: 220-227. doi: 10.1016/j.clim.2014.04.013
  • Gagliardi, Lucia; Schreiber, Andreas W.; Hahn, Christopher N.; Feng, Jinghua; Cranston, Treena; Boon, Hannah; Hotu, Cheri; Oftedal, Bergithe Eikeland; Cutfield, Richard; Adelson, David L.; Braund, Wilton J.; Gordon, Richard D.; Rees, D. Aled; Grossman, Ashley B.; Torpy, David J.; Scott, Hamish S. 2014. ARMC5 mutations are common in familial bilateral macronodular adrenal hyperplasia. Journal of Clinical Endocrinology and Metabolism. 99: E1784-E1792. doi: 10.1210/jc.2014-1265
  • Wolff, Anette Susanne Bøe; Kärner, Jaanika; Owe, Jone Furulund; Oftedal, Bergithe Eikeland; Gilhus, Nils Erik; Erichsen, Martina Moter; Kämpe, Olle; Meager, Anthony; Peterson, Pärt; Kisand, Kai; Willcox, Nick; Husebye, Eystein Sverre. 2014. Clinical and serologic parallels to APS-I in patients with thymomas and autoantigen transcripts in their tumors. Journal of Immunology. 193: 3880-3890. doi: 10.4049/jimmunol.1401068
  • Oftedal, Bergithe Eikeland; Erichsen, Martina Moter; Hellesen, Alexander; Perheentupa, Jaako; Fiskarstrand, Torunn; Knappskog, Per; Abramson, Jakub; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre. 2013. Dominant Inheritance in Autoimmune Endocrine Syndrome Type 1. Scandinavian Journal of Immunology. 77: 306-307.
  • Wolff, Anette Susanne Bøe; Sarkadi, Adrien Katalin; Maródi, László; Kärner, Jaanika; Orlova, Elizaveta; Oftedal, Bergithe Eikeland; Kisand, Kai; Ólah, Éva; Meloni, Antonella; Myhre, Anne Grethe; Husebye, Eystein Sverre; Motaghedi, Roja; Perheentupa, Jaako; Peterson, Pärt; Willcox, Nick; Meager, Anthony. 2013. Anti-cytokine autoantibodies preceding onset of autoimmune polyendocrine syndrome type I features in early childhood. Journal of Clinical Immunology. 33: 1341-1348. doi: 10.1007/s10875-013-9938-6
  • Hapnes, Liv; Willcox, Nick; Oftedal, Bergithe Eikeland; Owe, Jone Furulund; Gilhus, Nils Erik; Meager, Anthony; Husebye, Eystein Sverre; Wolff, Anette Susanne Bøe. 2012. Radioligand-binding assay reveals distinct autoantibody preferences for type I interferons in APS I and myasthenia gravis subgroups. Journal of Clinical Immunology. 32: 230-237. doi: 10.1007/s10875-011-9617-4
  • Wolff, Anette Susanne Bøe; Ostre, A.; Oftedal, Bergithe Eikeland; Husebye, Eystein Sverre. 2012. Deviant expression of defensins in sera and saliva of patients with autoimmune polyendocrine syndrome type I. Immunology. 137: 211-212.
  • Oftedal, Bergithe Eikeland; Kämpe, Olle; Meager, Anthony; Ahlgren, Kerstin M.; Lobell, Anna; Husebye, Eystein Sverre; Wolff, Anette Susanne Bøe. 2011. Measuring autoantibodies against IL-17F and IL-22 in Autoimmune Polyendocrine Syndrome Type I by radioligand binding assay using fusion proteins. Scandinavian Journal of Immunology. 74: 327-333. doi: 10.1111/j.1365-3083.2011.02573.x
  • Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Kämpe, Olle; Husebye, Eystein Sverre. 2010. Nucleoporin 62, a Novel Autoantigen in Patients with Autoimmune Polyendocrine Syndrome Type I (APS I). Scandinavian Journal of Immunology. 71: 493-494.
  • Wolff, Anette Susanne Bøe; Oftedal, Bergithe Eikeland; Kisand, Kai; Ersvær, Elisabeth; Lima, Kari; Husebye, Eystein Sverre. 2010. Flow cytometry study of blood cell subtypes reflects autoimmune and inflammatory processes in autoimmune polyendocrine syndrome type I. Scandinavian Journal of Immunology. 71: 459-467. doi: 10.1111/j.1365-3083.2010.02397.x
  • Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Bratland, Eirik; Kämpe, Olle; Perheentupa, Jaakko; Myhre, Anne Grethe; Meager, Anthony; Purushothaman, Radhika; Ten, Svetlana; Husebye, Eystein Sverre. 2008. Radioimmunoassay for autoantibodies against interferon omega; its use in the diagnosis of autoimmune polyendocrine syndrome type I. Clinical Immunology. 129: 163-169. doi: 10.1016/j.clim.2008.07.002
  • Wolff, Anette Susanne Bøe; Oftedal, Bergithe Eikeland; Johansson, Stefan; Bruland, Ove; Løvås, Kristian; Meager, Anthony; Pedersen, Carsten; Husebye, Eystein Sverre; Knappskog, Per. 2008. AIRE variations in Addison's disease and autoimmune polyendocrine syndromes (APS): partial gene deletions contribute to APS I. Genes and Immunity. 9: 130-136. doi: 10.1038/sj.gene.6364457
  • Oftedal, Bergithe Eikeland; Ladstein, Sigve; Telle, Wenche; Male, Rune. 2005. Ligand-dependent protein interactions of the estrogen receptors using the yeast two-hybrid system. Annals of the New York Academy of Sciences. 1040: 420-425.
Rapporter/avhandlinger
  • Oftedal, Bergithe Eikeland. 2012. Autoimmune polyendocrine syndrome type I –novel diagnostic assays and immune regulation. University of Bergen.
  • Oftedal, Bergithe Eikeland. 2005. Exploring protein-protein interactions between ligand activated transcription factors using the yeast two-hybrid system. Molekylærbiologisk institutt, Universitetet i Bergen. 72 sider.

Se fullstendig oversikt over publikasjoner i CRIStin.

Immunologi, autoimmunitet, genetikk, immuncellerepertoar, autoantistoff

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