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Bergithe Eikeland Oftedals bilde

Bergithe Eikeland Oftedal

Forsker
  • E-postBergithe.Oftedal@uib.no
  • Besøksadresse
    Haukeland universitetssykehus, Laboratoriebygget
  • Postadresse
    Postboks 7804
    5020 Bergen

Post doc i gruppen Endokrin medisin ledet av Professor Eystein Husebye. Forsker på endokrin autoimmunitet, med spesielt fokus på den monogene autoimmune sykdommen autoimmun polyendokrin svikt type I (APS-I) og genet som forårsaker denne sykdommen, autoimmun regulator (AIRE) genet.

Vitenskapelig artikkel
  • Aslaksen, Sigrid; Wolff, Anette Susanne Bøe; Vigeland, Magnus Dehli; Breivik, Lars Ertesvåg; Sheng, Ying; Oftedal, Bergithe Eikeland; Skinningsrud, Beate; Undlien, Dag Erik; Selmer, Kaja Kristine; Husebye, Eystein Sverre; Bratland, Eirik. 2019. Identification and characterization of rare Toll-like receptor 3 variants in patients with autoimmune Addison’s disease. Journal of translational autoimmunity.
  • Aslaksen, Sigrid; Methlie, Paal; Vigeland, Magnus Dehli; Jøssang, Dag Eirik; Wolff, Anette Susanne Bøe; Sheng, Ying; Oftedal, Bergithe Eikeland; Skinningsrud, Beate; Undlien, Dag Erik; Selmer, Kaja Kristine; Husebye, Eystein Sverre; Bratland, Eirik. 2019. Coexistence of congenital adrenal hyperplasia and autoimmune Addison's disease. Frontiers in Endocrinology. 1-5.
  • Bruserud, Øyvind; Siddiqui, Huma; Cuida Marthinussen, Ileana Mihaela; Chen, Tsute; Jonsson, Roland; Oftedal, Bergithe Eikeland; Olsen, Ingar; Husebye, Eystein Sverre; Wolff, Anette Susanne Bøe. 2018. Oral microbiota in autoimmune polyendocrine syndrome type 1. Journal of Oral Microbiology. 1-10.
  • Berglund, Agnethe; Cleemann, Line ; Oftedal, Bergithe Eikeland; Holm, Kirsten; Husebye, Eystein Sverre; Gravholt, Claus H. 2018. 21-hydroxylase autoantibodies are more prevalent in Turner syndrome but without an association to the autoimmune polyendocrine syndrome type I. Clinical and Experimental Immunology. 1-5.
  • Oftedal, Bergithe Eikeland; Ardesjo Lundgren, Brita; Hamm, David; Gan, Poh-Yi; Holdsworth, Stephen R; Hahn, Christopher N.; Schreiber, Andreas W.; Scott, Hamish S. 2017. T cell receptor assessment in autoimmune disease requires access to the most adjacent immunologically active organ. Journal of Autoimmunity. 24-33.
  • Oftedal, Bergithe Eikeland; Cuida Marthinussen, Ileana Mihaela; Erichsen, Martina Moter; Tveitarås, Maria Kathrine; Kjellesvik-Kristiansen, Anja; Hammenfors, Daniel; Jonsson, Malin V; Kisand, Kai; Jonsson, Roland; Wolff, Anette Susanne Bøe. 2017. Impaired salivary gland activity in patients with autoimmune polyendocrine syndrome type I. Autoimmunity. 211-222.
  • Orlova, Elizaveta M.; Sozaeva, Leila S.; Kareva, Maria A.; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Breivik, Lars Ertesvåg; Zakharova, Ekaterina Y.; Ivanova, Olga N.; Kämpe, Olle; Dedov, Ivan I.; Knappskog, Per; Peterkova, Valentina A.; Husebye, Eystein Sverre. 2017. Expanding the Phenotypic and Genotypic Landscape of Autoimmune Polyendocrine Syndrome Type 1. Journal of Pediatric Endocrinology & Metabolism (JPEM). 3546-3556.
  • Bruserud, Øyvind; Bratland, Eirik; Hellesen, Alexander; Delaleu, Nicolas; Reikvam, Håkon; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe. 2017. Altered immune activation and IL-23 signaling in response to Candida albicans in autoimmune polyendocrine syndrome type 1. Frontiers in Immunology. 1-10.
  • Pazderska, Agnieszka; Oftedal, Bergithe Eikeland; Napier, Catherine M.; Ainsworth, Holly F.; Husebye, Eystein Sverre; Cordell, Heather J.; Pearce, Simon H.S.; Mitchell, Anna L. 2016. A variant in the BACH2 gene is associated with susceptibility to autoimmune addison's disease in humans. Journal of Clinical Endocrinology and Metabolism. 3865-3869.
  • Bruserud, Øyvind; Oftedal, Bergithe Eikeland; Landegren, Nils; Erichsen, Martina Moter; Bratland, Eirik; Lima, Kari; Jørgensen, Anders Palmstrøm; Myhre, Anne Grethe; Svartberg, Johan; Fougner, Kristian J; Bakke, Åsne; Nedrebø, Bjørn Gunnar; Mella, Bjarne; Breivik, Lars Ertesvåg; Viken, Marte K; Knappskog, Per; Cuida Marthinussen, Ileana Mihaela; Løvås, Kristian; Kämpe, Olle; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre. 2016. A longitudinal follow-up of autoimmune polyendocrine syndrome type 1. Journal of Clinical Endocrinology and Metabolism. 2975-2983.
  • Hu, Zhiqiang; Scott, Hamish S.; Qin, Guangrong; Zheng, Guangyong; Chu, Xixia; Xie, Lu; Adelson, David L.; Oftedal, Bergithe Eikeland; Venugopal, Parvathy; Babic, Milena; Hahn, Christopher N.; Zhang, Bing; Wang, Xiaojing; Li, Nan; Wei, Chaochun. 2015. Revealing missing human protein isoforms based on Ab initio prediction, RNA-seq and proteomics. Scientific Reports.
  • Oftedal, Bergithe Eikeland; Hellesen, Alexander; Erichsen, Martina Moter; Bratland, Eirik; Vardi, Ayelet; Perheentupa, Jaakko; Kemp, E. Helen; Fiskerstrand, Torunn; Viken, Marte K; Weetman, Anthony P.; Fleishman, Sarel J.; Banka, Siddharth; Newman, William G.; Sewell, William A. Carrock; Sozaeva, Leila S.; Zayats, Tetyana; Haugarvoll, Kristoffer; Orlova, Elizaveta M.; Haavik, Jan; Johansson, Stefan; Knappskog, Per; Løvås, Kristian; Wolff, Anette Susanne Bøe; Abramson, Jakub; Husebye, Eystein Sverre. 2015. Dominant mutations in the autoimmune regulator AIRE are associated with common organ-specific autoimmune diseases. Immunity. 1185-1196.
  • Mordaunt, Dylan; Oftedal, Bergithe Eikeland; McLauchlan, Alisha; Coates, Danika; Waters, Wendy; Scott, Hamish; Barnett, Christopher. 2015. 8q13.1-q13.2 deletion associated with inferior cerebellar vermian hypoplasia and digital anomalies: A new syndrome? Pediatric Neurology. 230-234.e1.
  • Wolff, Anette Susanne Bøe; Kärner, Jaanika; Owe, Jone Furulund; Oftedal, Bergithe Eikeland; Gilhus, Nils Erik; Erichsen, Martina Moter; Kämpe, Olle; Meager, Anthony; Peterson, Pärt; Kisand, Kai; Willcox, Nick; Husebye, Eystein Sverre. 2014. Clinical and serologic parallels to APS-I in patients with thymomas and autoantigen transcripts in their tumors. Journal of Immunology. 3880-3890.
  • Gagliardi, Lucia; Schreiber, Andreas W.; Hahn, Christopher N.; Feng, Jinghua; Cranston, Treena; Boon, Hannah; Hotu, Cheri; Oftedal, Bergithe Eikeland; Cutfield, Richard; Adelson, David L.; Braund, Wilton J.; Gordon, Richard D.; Rees, D. Aled; Grossman, Ashley B.; Torpy, David J.; Scott, Hamish S. 2014. ARMC5 mutations are common in familial bilateral macronodular adrenal hyperplasia. Journal of Clinical Endocrinology and Metabolism. E1784-E1792.
  • Breivik, Lars Ertesvåg; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Bratland, Eirik; Orlova, Elizaveta M.; Husebye, Eystein Sverre. 2014. A novel cell-based assay for measuring neutralizing autoantibodies against type I interferons in patients with autoimmune polyendocrine syndrome type 1. Clinical Immunology. 220-227.
  • Wolff, Anette Susanne Bøe; Sarkadi, Adrien Katalin; Maródi, László; Kärner, Jaanika; Orlova, Elizaveta; Oftedal, Bergithe Eikeland; Kisand, Kai; Ólah, Éva; Meloni, Antonella; Myhre, Anne Grethe; Husebye, Eystein Sverre; Motaghedi, Roja; Perheentupa, Jaako; Peterson, Pärt; Willcox, Nick; Meager, Anthony. 2013. Anti-cytokine autoantibodies preceding onset of autoimmune polyendocrine syndrome type I features in early childhood. Journal of Clinical Immunology. 1341-1348.
  • Hapnes, Liv; Willcox, Nick; Oftedal, Bergithe Eikeland; Owe, Jone Furulund; Gilhus, Nils Erik; Meager, Anthony; Husebye, Eystein Sverre; Wolff, Anette Susanne Bøe. 2012. Radioligand-binding assay reveals distinct autoantibody preferences for type I interferons in APS I and myasthenia gravis subgroups. Journal of Clinical Immunology. 230-237.
  • Oftedal, Bergithe Eikeland; Kämpe, Olle; Meager, Anthony; Ahlgren, Kerstin M.; Lobell, Anna; Husebye, Eystein Sverre; Wolff, Anette Susanne Bøe. 2011. Measuring autoantibodies against IL-17F and IL-22 in Autoimmune Polyendocrine Syndrome Type I by radioligand binding assay using fusion proteins. Scandinavian Journal of Immunology. 327-333.
  • Wolff, Anette Susanne Bøe; Oftedal, Bergithe Eikeland; Kisand, Kai; Ersvær, Elisabeth; Lima, Kari; Husebye, Eystein Sverre. 2010. Flow cytometry study of blood cell subtypes reflects autoimmune and inflammatory processes in autoimmune polyendocrine syndrome type I. Scandinavian Journal of Immunology. 459-467.
  • Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Bratland, Eirik; Kämpe, Olle; Perheentupa, Jaakko; Myhre, Anne Grethe; Meager, Anthony; Purushothaman, Radhika; Ten, Svetlana; Husebye, Eystein Sverre. 2008. Radioimmunoassay for autoantibodies against interferon omega; its use in the diagnosis of autoimmune polyendocrine syndrome type I. Clinical Immunology. 163-169.
  • Wolff, Anette Susanne Bøe; Oftedal, Bergithe Eikeland; Johansson, Stefan; Bruland, Ove; Løvås, Kristian; Meager, Anthony; Pedersen, Carsten; Husebye, Eystein Sverre; Knappskog, Per. 2008. AIRE variations in Addison's disease and autoimmune polyendocrine syndromes (APS): partial gene deletions contribute to APS I. Genes and Immunity. 130-136.
  • Oftedal, Bergithe Eikeland; Ladstein, Sigve; Telle, Wenche; Male, Rune. 2005. Ligand-dependent protein interactions of the estrogen receptors using the yeast two-hybrid system. Annals of the New York Academy of Sciences. 420-425.
Fagbok
  • Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe. 2019. Thymus transcriptome and Cell biology; Chapter 8. Springer.
Mastergradsoppgave
  • Oftedal, Bergithe Eikeland. 2005. Exploring protein-protein interactions between ligand activated transcription factors using the yeast two-hybrid system.
Doktorgradsavhandling
  • Bruserud, Øyvind. 2019. Exploring and redefining Autoimmune polyendocrine syndrome type 1.
  • Oftedal, Bergithe Eikeland. 2012. Autoimmune polyendocrine syndrome type I –novel diagnostic assays and immune regulation.
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
  • Wolff, Anette Susanne Bøe; Oftedal, Bergithe Eikeland; Husebye, Eystein Sverre. 2019. Polyendocrine disorders and endocrine neoplastic syndromes Chapter 2-1 "The Natural History of APS1. 7 sider.
  • Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe. 2019. Aire Mutations and Autoimmune Diseases. 24 sider.
Sammendrag/abstract
  • Oftedal, Bergithe Eikeland; Erichsen, Martina Moter; Hellesen, Alexander; Perheentupa, Jaako; Fiskarstrand, Torunn; Knappskog, Per; Abramson, Jakub; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre. 2013. Dominant Inheritance in Autoimmune Endocrine Syndrome Type 1. Scandinavian Journal of Immunology. 306-307.
  • Wolff, Anette Susanne Bøe; Ostre, A.; Oftedal, Bergithe Eikeland; Husebye, Eystein Sverre. 2012. Deviant expression of defensins in sera and saliva of patients with autoimmune polyendocrine syndrome type I. Immunology. 211-212.
  • Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Kämpe, Olle; Husebye, Eystein Sverre. 2010. Nucleoporin 62, a Novel Autoantigen in Patients with Autoimmune Polyendocrine Syndrome Type I (APS I). Scandinavian Journal of Immunology. 493-494.
Poster
  • Breivik, Lars Ertesvåg; Oftedal, Bergithe Eikeland; Bratland, Eirik; Wolff, Anette Susanne Bøe; Orlova, Elizaveta; Husebye, Eystein Sverre. 2013. A novel cell-based assay for measuring neutralizing autoantibodies against type I interferons in patients with APS-1.
Vitenskapelig oversiktsartikkel/review
  • Bruserud, Øyvind; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre. 2016. AIRE-mutations and autoimmune disease. 8-15.

Se fullstendig oversikt over publikasjoner i CRIStin.

Immunologi, autoimmunitet, genetikk, immuncellerepertoar, autoantistoff

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