Eivind Valen
Professor, Associate group leader at Sars Centre and NCMM
- E-postEivind.Valen@uib.no
- Telefon+47 55 58 40 74
- BesøksadresseHIB / Thormøhlensgt. 55Rom5133
- PostadressePostboks 78035020 Bergen
Diverse:
Presse:
- Nye metoder for lesing av DNA gir bedre utsikter
- Oppdagelsen av Apela/Toddler
- Rekruttering til Bergen
- Kartleggingen av menneskets promotere
Intervjuer:
- Forskerforum - Her er forskernes beste tips for å holde seg faglig oppdatert
- Forskning.no - Så langt har forskere kommet med å bruke gensaksen CRISPR på mennesker
- Forskning.no - Dataprogram avdekker fusk i cellene dine
- Forskningsetikk og Teknisk Ukeblad - Frykt og håp rundt ny genteknologi
- Bergen Film Festival - Alt du vil vite om CRISPR (men ikke våger å spørre om)
- Arendalsuka - KUNSTIG INTELLIGENS I HELSESEKTOREN: NØKKELEN TIL ET LENGRE LIV, MEN…?
Videoer:
Jeg underviser BINF201: Introduksjon til Omics
Vitenskapelig artikkel
- (2022). Nano3P-seq: transcriptome-wide analysis of gene expression and tail dynamics using end-capture nanopore cDNA sequencing. Nature Methods.
- (2022). Long-read single-molecule RNA structure sequencing using nanopore. Nucleic Acids Research (NAR). 11 sider.
- (2021). Rapid genome editing by CRISPR-Cas9-POLD3 fusion. eLIFE. 28 sider.
- (2021). ORFik: a comprehensive R toolkit for the analysis of translation. BMC Bioinformatics. 1-16.
- (2021). Deep conservation of ribosome stall sites across RNA processing genes. NAR Genomics and Bioinformatics. 1-13.
- (2021). CRISPR Genome Editing Made Easy Through the CHOPCHOP Website. Current Protocols in Bioinformatics.
- (2020). Profiling of Small Ribosomal Subunits Reveals Modes and Regulation of Translation Initiation. Cell reports. 18 sider.
- (2020). Intellectual disability in KATP channel neonatal diabetes. Diabetes Care. 526-533.
- (2020). Chromatin accessibility established by Pou5f3, Sox19b and Nanog primes genes for activity during zebrafish genome activation. PLoS Genetics. 1-25.
- (2020). Assessment of tumor suppressor promoter methylation in healthy individuals. Clinical Epigenetics. 1-15.
- (2019). tailfindr: Alignment-free poly(A) length measurement for Oxford Nanopore RNA and DNA sequencing. RNA: A publication of the RNA Society. 1229-1241.
- (2019). Trans-splicing of mRNAs links gene transcription to translational control regulated by mTOR. BMC Genomics.
- (2019). CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing. Nucleic Acids Research (NAR). W171-W174.
- (2019). Accurate analysis of genuine CRISPR editing events with ampliCan. Genome Research. 843-847.
- (2018). Shoelaces: An interactive tool for ribosome profiling processing and visualization. BMC Genomics. 6 sider.
- (2017). Ribosome signatures aid bacterial translation initiation site identification. BMC Biology. 1-14.
- (2017). REPARATION: ribosome profiling assisted (re-) annotation of bacterial genomes. Nucleic Acids Research (NAR).
- (2016). Internal guide RNA interactions interfere with Cas9-mediated cleavage. Nature Communications.
- (2016). CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering. Nucleic Acids Research (NAR).
- (2015). Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus. Cell reports. 875-883.
- (2014). Nuclear stability and transcriptional directionality separate functionally distinct RNA species. Nature Communications.
Faglig foredrag
- (2022). Rapid genome editing by CRISPR-Cas9-POLD3 fusion. .
Leder
- (2022). Nye CRISPR-metoder og mer presis presisjonsmedisin. Tidsskrift for Den norske legeforening.
Doktorgradsavhandling
- (2019). Understanding translational landscapes through the footprints of ribosomes.
Poster
- (2022). CRISPR-Cas9 T cell editing pipeline for Finnish founder diseases.
Vitenskapelig oversiktsartikkel/review
- (2022). Small Open Reading Frames, How to Find Them and Determine Their Function. Frontiers in Genetics.
- (2021). Transcript Isoform-Specific Estimation of Poly(A) Tail Length by Nanopore Sequencing of Native RNA. Methods in molecular biology. 543-567.
Discovering novel micropeptides
Pervasive translation
The function of long non-coding RNAs
Cas9 genome engineering