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Universitetet i Bergen
Hans Peter Martis bilde

Hans Peter Marti

Professor, Leader of the Renal Research Group and Overlege at Nephrology, Department of Medicine, Haukeland University Hospital, Helse Bergen
Klinisk institutt 1
Vis CV
  • E-postHans-Peter.Marti@uib.no
  • Besøksadresse
    Haukeland Universitetssykehus Laboratoriebygget, 7. etg. Heis øst
    5009 Bergen
  • Postadresse
    Postboks 7804
    5020 Bergen

Please see "Projects" and:

http://www.uib.no/en/rg/nephro

Responsible for nephrology teaching at UiB. Potential supervisor for Marie S. Curie fellows:

Link to Master Class UiB page https://www.uib.no/boa/112242/bergen-msca-if-master-class-201718

Link to the Euraxess advert https://euraxess.ec.europa.eu/jobs/funding/expand-your-horizons-msca-individual-fellowship-university-bergen-uib-norway

Vitenskapelig artikkel
  • Vis forfatter(e) (2022). Reduced α-galactosidase A activity in zebrafish (Danio rerio) mirrors distinct features of Fabry nephropathy phenotype. Molecular Genetics and Metabolism Reports. 1-11.
  • Vis forfatter(e) (2022). Proteomic signature of tubulointerstitial tissue predicts prognosis in IgAN. BMC Nephrology. 1-10.
  • Vis forfatter(e) (2022). Imaging of Clear Cell Renal Carcinoma with Immune Checkpoint Targeting Aptamer-Based Probe. Pharmaceuticals. 19 sider.
  • Vis forfatter(e) (2022). Chronic Kidney Disease from Polyvinylpyrrolidone Deposition in Persons with Intravenous Drug Use. American Society of Nephrology. Clinical Journal. 518-526.
  • Vis forfatter(e) (2022). Association of redox and inflammation-related biomarkers with prognosis in IgA nephropathy: A prospective observational study. Free Radical Biology & Medicine. 62-70.
  • Vis forfatter(e) (2021). Ultrasound and Microbubbles Enhance Uptake of Doxorubicin in Murine Kidneys. Pharmaceutics.
  • Vis forfatter(e) (2021). Medication Prescription, Common Side-effects, and Nutritional Status are Associated in Patients With Chronic Kidney Disease. Journal of renal nutrition. 1-9.
  • Vis forfatter(e) (2021). Familial contributions to the association between low birth weight and risk of CKD in adult life. Kidney International Reports. 2151-2158.
  • Vis forfatter(e) (2021). Factors associated with nutritional risk in patients receiving haemodialysis assessed by Nutritional Risk Screening 2002 (NRS2002). Journal of Renal Care. 1-7.
  • Vis forfatter(e) (2021). Elevated Ambulatory Blood Pressure Measurements are Associated with a Progressive Form of Fabry Disease. High Blood Pressure & Cardiovascular Prevention. 309-319.
  • Vis forfatter(e) (2021). Cardiovascular changes in young renal failure patients. Clinical Kidney Journal (CKJ).
  • Vis forfatter(e) (2021). Axl-inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model. Journal of Cellular and Molecular Medicine. 7407-7417.
  • Vis forfatter(e) (2021). AXL targeting by a specific small molecule or monoclonal antibody inhibits renal cell carcinoma progression in an orthotopic mice model. Physiological Reports. 1-11.
  • Vis forfatter(e) (2021). AGAP2-AS1 as a prognostic biomarker in low-risk clear cell renal cell carcinoma patients with progressing disease. Cancer Cell International. 12 sider.
  • Vis forfatter(e) (2021). A map of metabolic phenotypes in patients with myalgic encephalomyelitis/chronic fatigue syndrome. JCI Insight. 1-19.
  • Vis forfatter(e) (2020). The changing landscape of Fabry disease. Journal of the American Society of Nephrology. 569-576.
  • Vis forfatter(e) (2020). Intrauterine growth restriction, preterm birth and risk of end-stage renal disease during the first 50 years of life. Nephrology, Dialysis and Transplantation. 1157-1163.
  • Vis forfatter(e) (2020). Intrauterine growth restriction and risk of diverse forms of kidney disease during the first 50 years of life. American Society of Nephrology. Clinical Journal. 1413-1423.
  • Vis forfatter(e) (2020). Circulating inflammation-related factors are correlated with systemic redox status in IgA nephropathy; a case-control study. Free Radical Biology & Medicine. 10-18.
  • Vis forfatter(e) (2019). Transcriptome-proteome integration of archival human renal cell carcinoma biopsies enables identification of molecular mechanisms. American Journal of Physiology - Renal Physiology (AJP).
  • Vis forfatter(e) (2019). Characterization of glomerular extracellular matrix in IgA nephropathy by proteomic analysis of laser-captured microdissected glomeruli. BMC Nephrology. 1-12.
  • Vis forfatter(e) (2019). Challenges and opportunities for nephrology in Western Europe. Kidney International. 1037-1040.
  • Vis forfatter(e) (2019). AXL targeting reduces fibrosis development in experimental unilateral ureteral obstruction. Physiological Reports. 1-20.
  • Vis forfatter(e) (2018). Systemic redox biomarkers and their relationship to prognostic risk markers in autosomal dominant polycystic kidney disease and IgA nephropathy. Clinical Biochemistry. 33-40.
  • Vis forfatter(e) (2018). Low birth weight associates with glomerular area in young male IgA nephropathy patients. BMC Nephrology. 1-10.
  • Vis forfatter(e) (2018). In vivo detection of chronic kidney disease using tissue deformation fields from dynamic MR imaging. IEEE Transactions on Biomedical Engineering. 1779-1790.
  • Vis forfatter(e) (2018). High rates of central obesity and sarcopenia in CKD irrespective of renal replacement therapy - An observational cross-sectional study. BMC Nephrology. 1-9.
  • Vis forfatter(e) (2018). Fine needle aspirates of kidneys: A promising tool for RNA sequencing in native and transplanted kidneys. BMC Nephrology. 1-9.
  • Vis forfatter(e) (2018). Expanding the utilization of formalin-fixed, paraffin-embedded archives: Feasibility of miR-Seq for disease exploration and biomarker development from biopsies with clear cell renal cell Carcinoma. International Journal of Molecular Sciences. 1-18.
  • Vis forfatter(e) (2017). Renal carcinoma/kidney progenitor cell chimera organoid as a novel tumorigenesis gene discovery model. Disease Models and Mechanisms. 1503-1515.
  • Vis forfatter(e) (2017). Renal Carcinoma/Kidney Progenitor Cell Chimera Organoid as a Novel Tumourigenesis Gene Discovery Model. Disease Models and Mechanisms. 1930-1942.
  • Vis forfatter(e) (2017). Pathomechanisms of renal Fabry disease. Cell and Tissue Research. 53-62.
  • Vis forfatter(e) (2017). Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy. Clinical Proteomics.
  • Vis forfatter(e) (2017). Disease progression modeling to evaluate the effects of enzyme replacement therapy on kidney function in adult patients with the Classic phenotype of Fabry disease. Kidney and Blood Pressure Research. 1-15.
  • Vis forfatter(e) (2017). Clear cell renal cell carcinoma is linked to epithelial-to-mesenchymal transition and to fibrosis. Physiological Reports. 1-18.
  • Vis forfatter(e) (2016). Transcriptome sequencing (RNAseq) enables utilization of formalin-fixed, paraffin-embedded biopsies with clear cell renal cell carcinoma for exploration of disease biology and biomarker development. PLOS ONE.
  • Vis forfatter(e) (2016). Renal fibrosis mRNA classifier: Validation in experimental lithium-induced interstitial fibrosis in the rat kidney. PLOS ONE.
  • Vis forfatter(e) (2016). RNA extraction for RNA sequencing of archival renal tissues. Scandinavian Journal of Clinical and Laboratory Investigation. 426-434.
  • Vis forfatter(e) (2016). Proteomic Analysis of Minimally Damaged Renal Tubular Tissue from Two-Kidney-One-Clip Hypertensive Rats Demonstrates Extensive Changes Compared to Tissue from Controls. Nephron. 70-80.
  • Vis forfatter(e) (2016). Next generation sequencing: A tool for this generation of nephrologists. European Medical Journal: Nephrology. 50-57.
  • Vis forfatter(e) (2016). Low birth weight and risk of progression to end stage renal disease in IgA nephropathy - A retrospective registry-based cohort study. PLOS ONE.
  • Vis forfatter(e) (2016). Exploring frailty and mild cognitive impairment in kidney transplantation to predict biomedical, psychosocial and health cost outcomes (GERAS): protocol of a nationwide prospective cohort study. Journal of Advanced Nursing.
  • Vis forfatter(e) (2016). End stage renal disease predicts increased risk of death in first degree relatives in the Norwegian population. PLOS ONE.
  • Vis forfatter(e) (2016). Development and confirmation of potential gene classifiers of human clear cell renal cell carcinoma using next-generation RNA sequencing. Scandinavian Journal of Urology. 452-462.
  • Vis forfatter(e) (2015). PTX3 Polymorphisms and Invasive Mold Infections after Solid Organ Transplantation. Clinical Infectious Diseases. 619-622.
  • Vis forfatter(e) (2015). Distinct protein signature of hypertension-induced damage in the renal proteome of two-kidney-one-clip (2K1C) rat model. Journal of Hypertension. 126-135.
  • Vis forfatter(e) (2015). CRTC2 polymorphism as a risk factor for the incidence of metabolic syndrome in patients with solid organ transplantation. Pharmacogenomics (London).
  • Vis forfatter(e) (2015). Bedeutung und management der Rezidive von Glomerulonephritiden im Nierentransplantat (Significance and management of recurrent glomerulonephritis in kidney transplantation). Therapeutische Umschau. 199-206.
  • Vis forfatter(e) (2014). Metzincins and related genes in experimental renal aging: towards a unifying fibrosis classifier across species. Nephrology, Dialysis and Transplantation. 1177-1185.
  • Vis forfatter(e) (2014). Correlation of serum and urinary matrix metalloproteases/tissue inhibitors of metalloproteases with subclinical allograft fibrosis in renal transplantation. Transplant Immunology. 1-6.
Vitenskapelig foredrag
  • Vis forfatter(e) (2021). Cleared Podocytes and Normal Kidney Function in Classical Fabry Males 15 Years After Start of Enzyme Replacement Therapy at Young Age.
  • Vis forfatter(e) (2019). Fabry Nephropathy: First mRNA-seq Findings from Kidney Biopsies Before and After Enzyme Replacement Therapy.
  • Vis forfatter(e) (2018). Primary Membranous Nephropathy: Glomerular RNA Sequencing from Archival Kidney Biopsies.
Leder
  • Vis forfatter(e) (2019). Challenging Anticoagulation in Advanced Renal Failure. American Journal of Medicine. 1258-1259.
Short communication
  • Vis forfatter(e) (2020). The case: Kidney injury in a patient receiving nivolumab. Kidney International. 1359-1360.
  • Vis forfatter(e) (2018). Klarcellet nyrekarsinom er knyttet til epitelial-til- mesenkymal overgang (EMT) og til fibrose. Best Practice Norge. Onkologi/hemtologi.
Brev til redaktøren
  • Vis forfatter(e) (2021). Low Immunization Rate in Kidney Transplant Recipients Also After Dose 2 of the BNT162b2 Vaccine: Continue to Keep Your Guard up! Transplantation. E80-E81.
  • Vis forfatter(e) (2015). Renal failure due to excessive intake of almonds in the absence of Oxalobacter Formigenes. American Journal of Medicine. e29-e30.
  • Vis forfatter(e) (2015). Renal Failure due to Excessive Intake of Almonds in the Absence of Oxalobacter formigenes. American Journal of Medicine.
Doktorgradsavhandling
  • Vis forfatter(e) (2019). New methods clear the dust off old biopsies. RNA sequencing of FFPE kidney biopsies.
  • Vis forfatter(e) (2019). Epithelial-to-mesenchymal transition in clear cell renal cell cancer and renal fibrosis.
Poster
  • Vis forfatter(e) (2021). Synuclein Alpha Accumulation Drives Lysosomal Dysfunction in Fabry Podocytopathy.
  • Vis forfatter(e) (2020). Systems Analyses of Renal Fabry Transcriptome and Response to Enzyme Replacement Therapy (ERT) Identifies a Cross-Validated and Druggable ERT-Resistant Module.
  • Vis forfatter(e) (2020). RENAL POLYVINYLPYRROLIDONE DEPOSITION IN DRUG ADDICTED PATIENTS – HISTOLOGICAL AND ULTRASTRUCTURAL FINDINGS .
  • Vis forfatter(e) (2018). Fine needle aspirates of kidneys are usable for RNA sequencing like regular core biopsies.
  • Vis forfatter(e) (2018). Fabry nephropathy: Transcriptome sequencing of microdissected renal compartments from archival kidney biopsies at baseline, and after 5 & 10 years of enzyme replacement therapy.
  • Vis forfatter(e) (2018). Expanding the utilization of formalin-fixed, paraffin-embedded archives: Feasability of miRNA-sequencing for disease exploration and biomarker development from biopsies with clear cell renal cell carcinoma.
  • Vis forfatter(e) (2016). Development and Confirmation of Gene Classifiers of Human Clear Cell Renal Cell Carcinoma Using Next-Generation Sequencing [Abstract].
  • Vis forfatter(e) (2016). Detection and Validation of Epithelial-to-Mesenchymal Transition(EMT) with Increased Expression of Axl and MMP-14 in Renal Cell Carcinoma.
Errata
  • Vis forfatter(e) (2018). Correction to: High rates of central obesity and sarcopenia in CKD irrespective of renal replacement therapy - An observational cross-sectional study. BMC Nephrology.
Vitenskapelig oversiktsartikkel/review
  • Vis forfatter(e) (2021). International Society of Nephrology Global Kidney Health Atlas: structures, organization, and services for the management of kidney failure in Western Europe. Kidney International Supplements (KI Supplements). e106-e118.
  • Vis forfatter(e) (2020). Proteomics for the study of new biomarkers in Fabry disease: State of the art. Molecular Genetics and Metabolism. 86-93.
  • Vis forfatter(e) (2020). Fibrosis and Cancer: Shared Features and Mechanisms suggest common Targeted Therapeutic Approaches. Nephrology, Dialysis and Transplantation. 1-9.
  • Vis forfatter(e) (2016). Nephropathology: A cornerstone for understanding and estimation of recent advances in glomerular diseases. BANTAO Journal. 60-63.

Se fullstendig oversikt over publikasjoner i CRIStin.

Please see PubMed and CV

Main projects

  1. Novel biomarkers and therapeutic targets in Fabry nephropathy and in membranous nephropathy

  2. Therapy of experimental renal fibrosis with Axl receptor tyrosine kinase inhibitors

  3. Prognostic markers and therapy of human and experimental clear cell renal cell carcinoma

 

 Phone: +47 940 30 929

Kompetansefelt 
Animal models of fibrosis
Fabry nephropathy
Hypertension
Renal cell carcinoma
RNA sequencing from FFPE kidney biopsies