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Harald Gotten Wikers bilde

Harald Gotten Wiker

Professor, Knyttet til enhet for læring ved det medisinske fakultet Leder av programutvalget for medisin
  • E-postHarald.Wiker@uib.no
  • Telefon+47 55 58 61 95
  • Besøksadresse
    Armauer Hansens hus, Haukelandsveien 28
  • Postadresse
    Postboks 7804
    5020 Bergen

Clinical and experimental microbiology and immunology with an emphasis on characterization of bacteria using proteomic methods and the human microbiome using high throughput DNA sequencing     

ORCID https://orcid.org/0000-0001-9452-243X

LOOP   https://loop.frontiersin.org/people/2110415/overview

  • Vis forfatter(e) (2022). Klima og bærekraft i helseutdanningene. .
  • Vis forfatter(e) (2022). Fastlegevikar uten LIS1 er feil bruk av nye leger. Dagens medisin.
  • Vis forfatter(e) (2022). Consistent biofilm formation by streptococcus pyogenes emm 1 isolated from patients With necrotizing soft tissue infections. Frontiers in Microbiology. 1-8.
  • Vis forfatter(e) (2022). A longitudinal study of the pulmonary mycobiome in subjects with and without chronic obstructive pulmonary disease. PLOS ONE. 15 sider.
  • Vis forfatter(e) (2021). Repeated bronchoscopy in health and obstructive lung disease: is the airway microbiome stable? BMC Pulmonary Medicine. 1-12.
  • Vis forfatter(e) (2021). Rapport: Arbeidsgruppe for klima og bærekraft i helseutdanningene. .
  • Vis forfatter(e) (2021). Label-free quantitative proteomic analysis of the oral bacteria Fusobacterium nucleatum and Porphyromonas gingivalis to identify protein features relevant in biofilm formation. Anaerobe.
  • Vis forfatter(e) (2021). Immunochemistry-based diagnosis of extrapulmonary tuberculosis: A strategy for large-scale production of mpt64-antibodies for use in the mpt64 antigen detection test. Antibodies. 1-14.
  • Vis forfatter(e) (2021). Exploring protocol bias in airway microbiome studies: one versus two PCR steps and 16S rRNA gene region V3 V4 versus V4. BMC Genomics. 15 sider.
  • Vis forfatter(e) (2020). The airway microbiota and exacerbations of COPD. European Respiratory Journal Open Research (ERJ Open Research). 1-10.
  • Vis forfatter(e) (2020). Mycobacterial antigens accumulation in foamy macrophages in murine pulmonary tuberculosis lesions: Association with necrosis and making of cavities. Scandinavian Journal of Immunology. 1-13.
  • Vis forfatter(e) (2020). Levels of proteinase 3 and neutrophil elastase in plasma, BAL and biopsies in COPD. European Respiratory Journal.
  • Vis forfatter(e) (2020). Distinct Metabolic Features of Pathogenic Escherichia coli and Shigella spp. Determined by Label‐Free Quantitative Proteomics. Proteomics.
  • Vis forfatter(e) (2020). Diagnosis of extrapulmonary tuberculosis using the MPT64 antigen detection test in a high-income low tuberculosis prevalence setting. BMC Infectious Diseases. 1-11.
  • Vis forfatter(e) (2019). Sputum microbiota and inflammation at stable state and during exacerbations in a cohort of chronic obstructive pulmonary disease (COPD) patients. PLOS ONE. 1-18.
  • Vis forfatter(e) (2019). Repeated bronchoscopy examination of the airway microbiome. European Respiratory Journal.
  • Vis forfatter(e) (2019). On the impact of the pangenome and annotation discrepancies while building protein sequence databases for bacteria proteogenomics. Frontiers in Microbiology. 1-13.
  • Vis forfatter(e) (2019). Laboratory contamination in airway microbiome studies. BMC Microbiology. 1-13.
  • Vis forfatter(e) (2018). Mycobacterial antigen accumulation in foamy macrophages in pulmonary tuberculosis lesions is associated with tissue destruction and disease severity.
  • Vis forfatter(e) (2018). Comparative proteomics of enterotoxigenic escherichia coli reveals differences in surface protein production and similarities in metabolism. Journal of Proteome Research. 325-336.
  • Vis forfatter(e) (2017). Zoonotic necrotizing myositis caused by Streptococcus equi subsp. zooepidemicus in a farmer. BMC Infectious Diseases. 1-8.
  • Vis forfatter(e) (2017). Rapid and specific diagnosis of extrapulmonary tuberculosis by immunostaining of tissues and aspirates with anti-MPT64. Applied immunohistochemistry & molecular morphology (Print). 282-288.
  • Vis forfatter(e) (2017). Quantitative proteomic analysis of extracellular matrix extracted from mono- and dual-species biofilms of Fusobacterium nucleatum and Porphyromonas gingivalis. Anaerobe. 133-142.
  • Vis forfatter(e) (2017). Protected sampling is preferable in bronchoscopic studies of the airway microbiome. European Respiratory Journal Open Research (ERJ Open Research).
  • Vis forfatter(e) (2017). Implementation of a new immunohistochemistry-based test for diagnosing extrapulmonary tuberculosis by detection of mycobacterial antigen MPT64.
  • Vis forfatter(e) (2017). Comparing microbiota profiles in induced and spontaneous sputum samples in COPD patients. Respiratory Research. 1-9.
  • Vis forfatter(e) (2016). Coordination of metabolism and virulence factors expression of extraintestinal pathogenic Escherichia coli purified from blood cultures of patients with sepsis. Molecular & Cellular Proteomics. 2890-2907.
  • Vis forfatter(e) (2015). Phosphoproteomics analysis of a clinical Mycobacterium tuberculosis Beijing isolate: Expanding the mycobacterial phosphoproteome catalog. Frontiers in Microbiology.
  • Vis forfatter(e) (2015). Multiplex Analysis of Pro- or Anti-Inflammatory Serum Cytokines and Chemokines in relation to Gender and Age among Tanzanian Tuberculous Lymphadenitis Patients. Tuberculosis Research and Treatment.
  • Vis forfatter(e) (2015). Improving genome annotation of enterotoxigenic Escherichia coli TW10598 by a label-free quantitative MS/MS approach. Proteomics. 3826-3834.
  • Vis forfatter(e) (2014). The Bergen COPD microbiome study (MicroCOPD): rationale, design, and initial experiences. European Clinical Respiratory Journal.
  • Vis forfatter(e) (2014). Proteogenomics in microbiology: Taking the right turn at the junction of genomics and proteomics. Proteomics. 2360-2675.
  • Vis forfatter(e) (2014). Mycobacterial antigens disappear from host tissue during latent Mycobacterium tuberculosis infection.
  • Vis forfatter(e) (2014). Effect of non-tuberculous mycobacteria on host biomarkers potentially relevant for tuberculosis management. PLoS Neglected Tropical Diseases.
  • Vis forfatter(e) (2014). Differential in vivo expression of mycobacterial antigens in Mycobacterium tuberculosis infected lungs and lymph node tissues. BMC Infectious Diseases.
  • Vis forfatter(e) (2013). Antimicrobial effects of beta-glucans and pectin and of the Agaricus blazei-based mushroom extract, AndoSanTM. Examples of mouse models for pneumococcal-, fecal bacterial-, and mycobacterial infections. 10 sider.
  • Vis forfatter(e) (2012). Rapid diagnosis of tuberculosis in aspirate, effusions, and cerebrospinal fluid by immunocytochemical detection of Mycobacterium tuberculosis complex specific antigen MPT64. Diagnostic Cytopathology. 782-791.
  • Vis forfatter(e) (2012). Proteomic analysis of a multi-resistant clinical Escherichia coli isolate of unknown genomic background. Journal of Proteomics. 1830-1837.
  • Vis forfatter(e) (2012). Long-term persistence of BCG Pasteur in lungs of C57BL/6 mice following intranasal infection. Scandinavian Journal of Immunology. 489-499.
  • Vis forfatter(e) (2012). Improved signal peptide predictions in mycobacteria? Tuberculosis. 291-292.
  • Vis forfatter(e) (2012). Dual-priming oligonucleotides for broad-range amplification of the bacterial 16S rRNA gene directly from human clinical specimens. Journal of Clinical Microbiology. 1289-1294.
  • Vis forfatter(e) (2012). Aminoglycoside resistance in clinical Escherichia coli and Klebsiella pneumoniae isolates from Western Norway. APMIS - Journal of Pathologiy, Microbiology and Immunology. 495-502.
  • Vis forfatter(e) (2011). Targeted Vaccibodies against Mycobacterium tuberculosis. Scandinavian Journal of Immunology. 383-384.
  • Vis forfatter(e) (2011). Proteogenomic analysis of polymorphisms and gene annotation divergences in prokaryotes using a clustered mass spectrometry-friendly database. Molecular & Cellular Proteomics. 10 sider.
  • Vis forfatter(e) (2011). Comparison of membrane proteins of Mycobacterium tuberculosis H37Rv and H37Ra strains. BMC Microbiology.
  • Vis forfatter(e) (2011). Characterization of polybacterial clinical samples using a set of group-specific broad-range primers targeting the 16S rRNA gene followed by DNA sequencing and RipSeq analysis. Journal of Medical Microbiology. 927-936.
  • Vis forfatter(e) (2011). Bacterial proteins with cleaved or uncleaved signal peptides of the general secretory pathway. Journal of Proteomics. 502-510.
  • Vis forfatter(e) (2011). A quantitative view on Mycobacterium leprae antigens by proteomics. Journal of Proteomics. 1711-1719.
  • Vis forfatter(e) (2011). A proteomic view of mycobacteria. Proteomics. 3118-3127.
  • Vis forfatter(e) (2010). Using a Label-free Proteomics Method to Identify Differentially Abundant Proteins in Closely Related Hypo- and Hypervirulent Clinical Mycobacterium tuberculosis Beijing Isolates. Molecular & Cellular Proteomics. 2414-2423.
  • Vis forfatter(e) (2010). Serodiagnosis of tuberculous lymnphadenitis using a combination of antigens. Journal of Infection in Developing Countries. 96-102.
  • Vis forfatter(e) (2010). Proteomic Approaches to Study Immunity in Infection. Methods in Microbiology. 101-114.
  • Vis forfatter(e) (2010). MSMSpdbb: providing protein databases of closely related organisms to improve proteomic characterization of prokaryotic microbes. Bioinformatics.
  • Vis forfatter(e) (2010). Evidence for waning of latency in a cohort study of tuberculosis. BMC Infectious Diseases.
  • Vis forfatter(e) (2010). Definition of novel cell envelope associated proteins in Triton X-114 extracts of Mycobacterium tuberculosis H37Rv. BMC Microbiology.
  • Vis forfatter(e) (2010). Comparison of Immune Response in Mice Infected with M-Bovis BCG Russia and M-Bovis BCG Pasteur. Scandinavian Journal of Immunology. 536-536.
  • Vis forfatter(e) (2010). Analysis of detergent-insoluble and whole cell lysate fractions of resting neutrophils using high-resolution mass spectrometry. Journal of Proteome Research. 2030-2036.
  • Vis forfatter(e) (2009). Virulensfaktorer og immunitet ved mykobakterieinfeksjoner.
  • Vis forfatter(e) (2009). Validating divergent ORF annotation of the Mycobacterium leprae genome through a full translation dataset and peptide identification by tandem mass spectrometry. Proteomics. 3233-3243.
  • Vis forfatter(e) (2009). The impact of proteomic advances on bacterial gene annotation. Current Proteomics. 84-92.
  • Vis forfatter(e) (2009). Searching for new vaccine candidates - Proteomics against tuberculosis.
  • Vis forfatter(e) (2009). Proteomic analysis of total cellular proteins of human neutrophils. Proteome Science.
  • Vis forfatter(e) (2009). MPB70 and MPB83 - Major Antigens of Mycobacterium bovis. Scandinavian Journal of Immunology. 492-499.
  • Vis forfatter(e) (2009). Kongelig tuberkulose-innblikk.
  • Vis forfatter(e) (2009). Identifisering av inntil tre ulike bakteriar direkte frå prøvematerialet ved hjelp av direkte 16S rDNA sekvensering.
  • Vis forfatter(e) (2009). Identification and genotyping of the etiological agent of tuberculous lymphadenitis in Ethiopia. Journal of Infection in Developing Countries. 412-419.
  • Vis forfatter(e) (2009). HIV Induces both a Down-Regulation of IRAK-4 that Impairs TLR Signalling and an Up-regulation of the Antibiotic Peptide Dermcidin in Monocytic Cells. Scandinavian Journal of Immunology. 264-276.
  • Vis forfatter(e) (2009). Fra krysset immunelektroforese til tandem massespektrometri.
  • Vis forfatter(e) (2009). Evaluation of signal peptide prediction algorithms for identification of mycobacterial signal peptides using sequence data from proteomic methods. Microbiology (Reading). 2375-2383.
  • Vis forfatter(e) (2009). Evaluation of signal peptide prediction algorithms for identification of mycobacterial signal peptides using sequence data from proteomic methods.
  • Vis forfatter(e) (2009). Direct 16S rDNA sequencing from clinical specimens with special focus on poly-bacterial samples and interpretation of mixed DNA chromatograms. Journal of Clinical Microbiology. 3562-3568.
  • Vis forfatter(e) (2009). Diffusion blotting for rapid production of multiple identical imprints from sodium dodecyl sulfate polyacrylamide gel electrophoresis on a solid support. Methods in molecular biology. 35-38.
  • Vis forfatter(e) (2009). Differential expression of mycobacterial antigen MPT64, apoptosis and inflammatory markers in multinucleated giant cells and epithelioid cells in granulomas caused by Mycobacterium tuberculosis.
  • Vis forfatter(e) (2009). Allergic sensitisation in tuberculosis patients at the time of diagnosis and following chemotherapy. BMC Infectious Diseases. 9 sider.
  • Vis forfatter(e) (2009). A label-free method identified differentially abundant proteins in related M.tuberculosis Beijing strains.
  • Vis forfatter(e) (2008). Validating divergent ORF annotation in M. tuberculosis datasets using a LTQ-Orbitrap.
  • Vis forfatter(e) (2008). Validating divergent ORF annotation in M. tuberculosis datasets using a LTQ-Orbitrap.
  • Vis forfatter(e) (2008). Validating divergent ORF annotation in M. tuberculosis datasets using LTQ-Orbitrap.
  • Vis forfatter(e) (2008). TB antigen identification.
  • Vis forfatter(e) (2008). Rapid and reliable quantification of mycobacteria inside macrophages in vitro and mice using real-time quantitative PCR.
  • Vis forfatter(e) (2008). Rapid and reliable quantification of Mycobacteria inside macrophages in vitro and mice mice using real-taime quantitative PCR.
  • Vis forfatter(e) (2008). Rapid and Specific Diagnosis of Tuberculous Pleuritis With Immunohistochemistry by Detecting Mycobacterium tuberculosis Complex Specific Antigen MPT64 in Patients From a HIV Endemic Area. Applied immunohistochemistry & molecular morphology (Print). 554-561.
  • Vis forfatter(e) (2008). Proteomic analysis of Mycobacterium leprae.
  • Vis forfatter(e) (2008). Proteomic analysis of Mycobacterium leprae.
  • Vis forfatter(e) (2008). Membrane- and membrane-associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies.
  • Vis forfatter(e) (2008). Membrane- and membrane-associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies.
  • Vis forfatter(e) (2008). Membrane- and membrane associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies. Proteomics. 1859-1870.
  • Vis forfatter(e) (2008). Matallergi - Hvor alvorlig er det? og hva er det man ikke tåler?
  • Vis forfatter(e) (2008). Historieløst om kost og leddgikt.
  • Vis forfatter(e) (2008). High accuracy mass spectrometry analysis as a tool to verify and improve gene annotation using Mycobacterium tuberculosis as an example. BMC Genomics. 13 sider.
  • Vis forfatter(e) (2008). Evaluation of signal peptide prediction algoritms using sequence data from proteomic methods.
  • Vis forfatter(e) (2008). Evaluation of signal peptide prediction algorithms using sequence data from proteomic methods.
  • Vis forfatter(e) (2008). Etiologi og resistensmønster ved urinveisinfeksjoner.
  • Vis forfatter(e) (2008). Estimating the half-life of latent Mycobacterium tuberculosis infection based on the decline of tuberculosis in Norway.
  • Vis forfatter(e) (2008). En vaksine mot nye epidemier.
  • Vis forfatter(e) (2008). Differential expression of mycobacterial antigen MPT64, apoptosis and inflammatory markers in multinucleated giant cells and epithelioid cells in granulomas caused by Mycobacterium tuberculosis. Virchows Archiv. 449-456.
  • Vis forfatter(e) (2008). Diagnosis of tuberculous lymphadenitis in Ethiopia: correlation with culture, histology and HIV status. The International Journal of Tuberculosis and Lung Disease. 1030-1036.
  • Vis forfatter(e) (2008). Den norske vaksinen - venn eller fiende?
  • Vis forfatter(e) (2008). Antigen analysis of Mycobacterium tuberculosis H37Rv culture filtrate proteins.
  • Vis forfatter(e) (2008). Antigen analysis of Mycobacterium tuberculosis H37Rv culture filtrate proteins. Scandinavian Journal of Immunology. 245-252.
  • Vis forfatter(e) (2008). Antigen analysis of Mycobacterium tuberculosis H37Rv culture filtrate.
  • Vis forfatter(e) (2008). Antigen analysis of Mycobacterium tuberculosis H37Rv culture filtrate.
  • Vis forfatter(e) (2007). Vaksiner - Dårligere tuberkulose-vaksine.
  • Vis forfatter(e) (2007). The secreted subproteome and determination of cleavage sites for Signal peptidase I.
  • Vis forfatter(e) (2007). Reduced apoptosis and increased inflammatory cytokines in granulomas caused by tuberculous compared to non-tuberculous mycobacteria: role of MPT64 antigen in apoptosis and immune response. Clinical and Experimental Immunology. 105-113.
  • Vis forfatter(e) (2007). Quantification and characterisation of IgG binding to mould spores by flow cytometry and scanning electron microscopy. Journal of Immunological Methods (JIM). 123-131.
  • Vis forfatter(e) (2007). Progress in serodiagnosis of Mycobacterium tuberculosis infection. Scandinavian Journal of Immunology. 176-191.
  • Vis forfatter(e) (2007). Nyttig Vaksine.
  • Vis forfatter(e) (2007). Innate and specific immune responses to Mycobacterium turberculosis.
  • Vis forfatter(e) (2007). Immunohistochemistry for the detection of Mycobacterium tuberculosis complex specific antigen (MPT64) improves the diagnosis of extrapulmonary tuberculosis caused by pathogenic mycobacteria. APMIS - Journal of Pathologiy, Microbiology and Immunology. 1316-1316.
  • Vis forfatter(e) (2007). Immunohistochemical diagnosis of abdominal and lymph node tuberculosis by detecting Mycobacterium tuberculosis complex specific antigen MPT64. Diagnostic Pathology.
  • Vis forfatter(e) (2007). Hvor lenge varer tuberkuløs latens?
  • Vis forfatter(e) (2007). Detection of mycobacterium tuberculosis specific antigens by immunohistochemical technique: application for improved diagnosis of abdominal tuberculosis.
  • Vis forfatter(e) (2007). Correlation of Mycobacterium tuberculosis antigen MPT64 expression and apoptosis in human tuberculosis lesions.
  • Vis forfatter(e) (2007). Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv. Proteomics. 1702-1718.
  • Vis forfatter(e) (2007). Antibody response to long-term and high-dose mould-exposed sawmill workers. Scandinavian Journal of Immunology. 711-718.
  • Vis forfatter(e) (2007). Analysis of exported proteins from Mycobacterium tuberculosis H37Rv.
  • Vis forfatter(e) (2006). Vaksiner mot tuberkulose. Tidsskrift for Den norske legeforening. 2678-2681.
  • Vis forfatter(e) (2006). Vaksiner mot tuberkulose. Tidsskrift for Den norske legeforening. 2678-2681.
  • Vis forfatter(e) (2006). Vaccine research in Norway: Status and future prospects.
  • Vis forfatter(e) (2006). Vaccine approaches to prevent tuberculosis. Scandinavian Journal of Immunology.
  • Vis forfatter(e) (2006). Vaccine approaches to prevent tuberculosis. Scandinavian Journal of Immunology. 243-250.
  • Vis forfatter(e) (2006). Secreted antigens of Mycobacterium tuberculosis H37Rv for novel vaccine design.
  • Vis forfatter(e) (2006). Secreted antigens of Mycobacterium tuberculosis H37Rv for novel vaccine design.
  • Vis forfatter(e) (2006). Revealing the secreted proteome of Mycobacterium tuberculosis H37Rv.
  • Vis forfatter(e) (2006). Ny vaksine mot tuberkulose i Bergen.
  • Vis forfatter(e) (2006). Mykobakterieinfeksjoner. Naturen. 114-120.
  • Vis forfatter(e) (2006). MRSA - status og framtid.
  • Vis forfatter(e) (2006). Late breaker: Revealing the secreted proteome of Mycobacterium tuberculosis H37Rv.
  • Vis forfatter(e) (2006). Kommentarer til MRSA retningslinjene basert på erfaringer fra epidemien i Hordaland.
  • Vis forfatter(e) (2006). Immunohistochemistry using a Mycobacterium tuberculosis complex specific antibody for improved diagnosis of tuberculous lymphadenitis. Modern Pathology. 1606-1614.
  • Vis forfatter(e) (2006). Immunoglobulin G antibodies against environmental moulds in a Norwegian healthy population shows a bimodal distribution for Aspergillus versicolor. Vox Sanguinis. 73-73.
  • Vis forfatter(e) (2006). Identification of secreted proteins of M. tuberculosis as a basis for vaccine development.
  • Vis forfatter(e) (2006). Functional insights from the molecular modelling of a novel two-component system. Biochemical and Biophysical Research Communications - BBRC. 1327-1333.
  • Vis forfatter(e) (2006). Cytokine profiles in tuberculosis patients and healthy subjects in response to complex and single antigens of Mycobacterium tuberculosis. FEMS Immunology and Medical Microbiology. 254-261.
  • Vis forfatter(e) (2006). Comparing the protein identifications obtained using two-dimensional gel electrophoresis or liquid chromatography mass spectrometry on the secreted proteome of Mycobacterium tuberculosis.
  • Vis forfatter(e) (2006). Aldri har flere blitt smittet.
  • Vis forfatter(e) (2005). Regulation of expression of MPB70 and MPB83 in Mycobacterium bovis BCG substrains.
  • Vis forfatter(e) (2005). Reduced expression of antigenic proteins MPB70 and MPB83 in Mycobacterium bovis BCG strains due to a start codon mutation in sigK. Molecular Microbiology. 1302-1313.
  • Vis forfatter(e) (2005). Predicting proteins exported through the general secretory pathway in Mycobacterium tuberculosis H37Rv.
  • Vis forfatter(e) (2005). Predicting proteins exported through the general secretory pathway in Mycobacterium tuberculosis H37Rv.
  • Vis forfatter(e) (2005). Plenary lecture: The secreted proteomes of Mycobacterium tuberculosis and Mycobacterium leprae.
  • Vis forfatter(e) (2005). Molekylær epidemiologi av MRSA utenfor sykehus.
  • Vis forfatter(e) (2005). Klistreprotein skaper vaksinekomplikasjoner.
  • Vis forfatter(e) (2005). Immunoglobulin G antibodies against environmental moulds in a Norwegian healthy population shows a bimodal distribution for Aspergillus versicolor. Scandinavian Journal of Immunology. 281-288.
  • Vis forfatter(e) (2005). Identification of N-terminal peptides by MALDI-TOF of processed proteins secreted through the general secretory pathway.
  • Vis forfatter(e) (2005). Identification of N-terminal peptides by MALDI-TOF of processed proteins secreted through the general secretory pathway.
  • Vis forfatter(e) (2005). Får vi snart en ny og bedre vaksine mot tuberkulose?
  • Vis forfatter(e) (2005). Expression of Mycobacterium bovis antigenic proteins MPB70 and MPB83 is controlled by the alternate sigma factor sigK.
  • Vis forfatter(e) (2005). Expression of Mycobacterium bovis antigenic proteins MPB70 and MPB83 is controlled by the alternate sigma factor sigK.
  • Vis forfatter(e) (2005). Epidemiological analysis of MRSA in two counties in western Norway.
  • Vis forfatter(e) (2005). Epidemiological analysis of MRSA in two counties in Western Norway.
  • Vis forfatter(e) (2005). Crystal Structure of Low Molecular Weight Protein Tyrosine Phosphatase (MPtpA) from Mycobacterium tuberculosis at 1.9 Å resolution. Journal of Bacteriology. 2175-2181.
  • Vis forfatter(e) (2005). Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis by homology modeling.
  • Vis forfatter(e) (2005). Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis by homology modeling. Tuberculosis. 337-345.
  • Vis forfatter(e) (2005). Assay for quantifying mould-specific IgG antibodies in serum by flow cytometry using intact mould spores.
  • Vis forfatter(e) (2005). Allergic sensitization in tuberculosis and leprosy patients. International Archives of Allergy and Immunology. 217-224.
  • Vis forfatter(e) (2004). Unmatched sequences in public databases - Exemplified by tuberculin-active protein. Scandinavian Journal of Immunology. 607-608.
  • Vis forfatter(e) (2004). Mould extracts increase the allergic response to ovalbumin in mice. Clinical and Experimental Allergy. 1634-1641.
  • Vis forfatter(e) (2004). Immunodominant B-cell epitope in the Mce1A mammalian cell entry protein of Mycobacterium tuberculosis cross-reacting with glutathione S-transferase. Scandinavian Journal of Immunology. 190-197.
  • Vis forfatter(e) (2004). A Case of Peanut Cross-Allergy to Lupine Flour in a Hot Dog Bread. International Archives of Allergy and Immunology. 36-39.
  • Vis forfatter(e) (2003). T- and B-cell epitopes in the secreted Mycobacterium bovis antigen MPB70 in mice. Scandinavian Journal of Immunology. 151-161.
  • Vis forfatter(e) (2003). Predicted molecular structure of the mammalian cell entry protein Mce1A of Mycobacterium tuberculosis. Biochemical and Biophysical Research Communications - BBRC. 442-447.
  • Vis forfatter(e) (2002). Improved cellular and humoral immune responses against Mycobacterium tuberculosis antigens after intramuscular DNA immunisation combined with muscle electroporation. Vaccine. 3370-3378.
  • Vis forfatter(e) (2002). Generation of antibodies to the signal peptide of the MPT83 lipoprotein of Mycobacterium tuberculosis. Scandinavian Journal of Immunology. 82-87.
  • Vis forfatter(e) (2002). Cross-reaction between mammalian cell entry (Mce) proteins of Mycobacterium tuberculosis. Scandinavian Journal of Immunology. 580-587.
  • Vis forfatter(e) (2001). Novel monoclonal antibodies against major antigens of Mycobacterium bovis. Scandinavian Journal of Immunology. 498-502.
  • Vis forfatter(e) (2001). Elevated antibody responses in patients with Crohn’s disease against a 14-kDa secreted protein purified from Mycobacterium avium subsp. paratuberculosis. Scandinavian Journal of Immunology. 198-203.
  • Vis forfatter(e) (2001). Elevated antibody responses in patients with Crohn's disease against a 14 kDa secreted protein purified from Mycobacterium avium subspecies paratuberculosis. Scandinavian Journal of Immunology. 198-203.
  • Vis forfatter(e) (2001). Characterization of the secreted MPT53 antigen of Mycobacterium tuberculosis. Infection and Immunity. 5936-5939.
  • Vis forfatter(e) (2000). Distinct differences in repertoires of low-molecular-mass secreted antigens of Mycobacterium avium complex and Mycobacterium tuberculosis. Journal of Clinical Microbiology. 4453-4458.
  • Vis forfatter(e) (2000). Alkyl hydroperoxide reductases C and D are major antigens constitutively expressed by Mycobacterium avium subsp. paratuberculosi. Infection and Immunity. 801-808.
  • Vis forfatter(e) (1999). The mammalian cell entry operon 1 (mce1) of Mycobacterium leprae and Mycobacterium tuberculosis. Microbial Pathogenesis. 173-177.
  • Vis forfatter(e) (1999). Searching for secreted proteins of Mycobacterium leprae. Indian Journal of Leprosy. 19-35.
  • Vis forfatter(e) (1999). Demonstration of expression of six proteins of the mammalian cell entry (mce1) operon of Mycobacterium tuberculosis by anti-peptide antibodies, enzyme-linked immunosorbent assay and reverse transcription-polymerase chain reaction. Scandinavian Journal of Immunology. 519-527.
  • Vis forfatter(e) (1999). Cloning, expression and significance of MPT53 for identification of secreted proteins of Mycobacterium tuberculosis. Microbial Pathogenesis. 207-219.
  • Vis forfatter(e) (1999). Cloning, expression and immunological reactivity of two mammalian cell entry proteins encoded by the mce1 operon pf Mycobacterium tuberculosis. Scandinavian Journal of Immunology. 510-518.
  • Vis forfatter(e) (1998). Secreted proteins of Mycobacterium leprae. Scandinavian Journal of Immunology. 577-584.
  • Vis forfatter(e) (1998). Protective effect of beta-glucan against Mycobacterium bovis BCG infection in Balb/c mice. Scandinavian Journal of Immunology. 548-553.
  • Vis forfatter(e) (1998). MPB70 and MPB83 as indicators of protein localization in mycobacterial cells. Infection and Immunity. 289-296.
  • Vis forfatter(e) (1998). Involvement of antilipoarabinomannan antibodies in classical complement activation in tuberculosis. Clinical and Laboratory Immunology. 211-218.
  • Vis forfatter(e) (1998). Immunochemical characterization of the MPB70/80 and MPB83 proteins of Mycobacterium bovis. Infection and Immunity. 1445-1452.
  • Vis forfatter(e) (1998). Diffusion blotting for rapid production of multiple identical imprints from SDS-PAGE on a solid support. Journal of Immunological Methods (JIM). 77-84.
  • Vis forfatter(e) (1998). Comparison of antigen-specific T-cell responses of tuberculosis patients using complex or single antigens of Mycobacterium tuberculosis. Scandinavian Journal of Immunology. 535-543.
  • Vis forfatter(e) (1998). B-cell epitopes and quantification of the ESAT-6 protein of Mycobacterium tuberculosis. Infection and Immunity. 717-723.
  • Vis forfatter(e) (1997). Molecular cloning, purification, and serological characterization of MPT63, a novel antigen secreted by Mycobacterium tuberculosis. Infection and Immunity. 16-23.
  • Vis forfatter(e) (1997). Gene cloning, expression and sequence determination of MPT63, a novel secreted antigen from Mycobacterium tuberculosis. Infection and Immunity. 16-23.
  • Vis forfatter(e) (1997). Different localization of the homologous MPB70 and MPB83 proteins of Mycobacterium bovis. Medical principles and practice. 84-90.
  • Vis forfatter(e) (1997). A novel mycobacterial antigen relevant to cellular immunity belongs to a family of secreted lipoproteins. Scandinavian Journal of Immunology. 445-451.
  • Vis forfatter(e) (1996). Heterogenous expression of the related MPB70 and MPB83 proteins distinguish various substrains of Mycobacterium bovis BCG and Mycobacterium tuberculosis H37Rv. Scandinavian Journal of Immunology. 374-380.
  • Vis forfatter(e) (1996). Evidence for occurrence of the ESAT-6 protein in Mycobacterium tuberculosis and virulent Mycobacterium bovis and for its absence in Mycobacterium bovis BCG. Infection and Immunity. 16-22.

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MD, PhD, Medical speciality in Immunology

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