- E-posthayley.macdonald@uib.no
- Telefon+47 55 58 62 71
- BesøksadresseJonas Lies vei 915009 Bergen
- PostadressePostboks 78075020 Bergen
Min forskning fokuserer på de atferdsmessige, nevrofysiologiske og genetiske mekanismene for impulskontroll, dvs. hvordan vi kontrollerer våre handlinger. Jeg er spesielt interessert i hvordan disse mekanismene kan påvirkes av dopamin-dysregulering som ved Parkinsons sykdom og andre dopaminrelaterte lidelser. Jeg bruker teknikker som ikke-invasiv hjernestimulering, genotyping, beregningsmodellering og elektroencefalografi for å undersøke mekanismer for impulskontroll.
Du kan lese litt mer om hennes mitt forskningsfokus i denne artikkelen.
- Leder for Bergen Dopamine Group (nettsted kommer snart), som er tilknyttet Bergen fMRI Group.
- Gjesteredaktør for spesialemnesamling for eksperimentell hjerneforskning, 'Dopaminsysteminvolvering i impulskontroll'
(NB: Du finner meg nå også på UiBs sider med etternavnet McCardle).
Emneansvarlig for PRPSYK303 (Biologisk psykologi)
- (2023). Performance on the balloon analogue risk task and anticipatory response inhibition task is associated with severity of impulse control behaviours in people with Parkinson’s disease. Experimental Brain Research. 1159-1172.
- (2022). Exploring stop signal reaction time over two sessions of the anticipatory response inhibition task. Experimental Brain Research. 3061-3072.
- (2024). Dopamine system involvement in impulse control. Experimental Brain Research.
Se fullstendig oversikt over publikasjoner i CRIStin.
Hall, A., Weightman, M., Jenkinson, N., MacDonald, H.J., (2023). Performance on the Balloon Analogue Risk Task and Anticipatory Response Inhibition Task is Associated with Severity of Impulse Control Behaviours in People with Parkinson’s Disease. Experimental Brain Research. doi: 10.1007/s00221-023-06584-y
Hall, A., Jenkinson, N., and MacDonald, H. J., (2022) Exploring Stop Signal Reaction Time Over Two Sessions of the Anticipatory Response Inhibition Task. Experimental Brain Research. 240(11). doi: 10.1007/s00221-022-06480-x
He, J.L., Hirst, R.J., Puri, R. … MacDonald, H.J., Chowdbury, N.S. … Puts, N.A.J. (2022) OSARI: an Open-Source Anticipated Response Inhibition task. Behav Res Methods. 54(3). doi:10.3758/s13428-021-01680-9
Hall, A., Weaver, S. R., …, MacDonald, H. J. (2021). Dopamine genetic risk score predicts impulse control behaviors in Parkinson's disease. Clin Park Relat Disord. 5. doi:10.1016/j.prdoa.2021.100113
MacDonald H.J., et al. (2021) The Role of Interhemispheric Communication During Complete and Partial Cancellation of Bimanual Responses. J Neurophysiol. 125(3). DOI: 10.1152/jn.00688.2020
MacDonald H. J., et al. (2019) Memory Deficits in Parkinson's Disease are Associated with Reduced Beta Power Modulation. Brain Communications. 1(1). DOI: 10.1093/braincomms/fcz040
Cirillo J, … MacDonald HJ, Byblow WD. (2018) Response Inhibition Activates Distinct Motor Cortical Inhibitory Processes. J Neurophysiol. 119(3). DOI: 10.1152/jn.00784.2017
MacDonald H.J., et al. (2017). An Activation Threshold Model for Response Inhibition. PLoS One. 12(1). DOI: 10.1371/journal.pone.0169320
Cowie M.J*, MacDonald H.J.*, et al. (2016) Proactive Modulation of Long-Interval Intracortical Inhibition During Response Inhibition. J Neurophysiol. 116(2). DOI: 10.1152/jn.00144.2016*Shared first authorship
MacDonald H.J., et al. (2016) Dopamine Gene Profiling to Predict Impulse Control and Effects of Dopamine Agonist Ropinirole. J Cogn Neurosci,10(7). DOI: 10.1162/jocn_a_00946
MacDonald, H. J., & Byblow, W. D. (2015). Does Response Inhibition Have Pre- and Postdiagnostic Utility in Parkinson's Disease? J Mot Behav, 47(1). DOI: 10.1080/00222895.2014.941784
Ackerley S.J., … MacDonald H.J., et al. (2015) Primed Physical Therapy Enhances Recovery of Upper Limb Function in Chronic Stroke Patients. Neurorehab & Neural Repair, 30(4). DOI: 10.1177/1545968315595285
MacDonald, H. J., et al. (2014). The Fall and Rise of Corticomotor Excitability with Cancellation and Reinitiation of Prepared Action. J Neurophysiol, 112(11). DOI: 10.1152/jn.00366.2014
MacDonald, H. J., e al. (2012). Uncoupling Response Inhibition. J Neurophysiol, 108(5). DOI: 10.1152/jn.01184.2011
Preprints
Ratcliffe, C. E., McAllister, C. J., and MacDonald, H. J., Dual-Coil Transcranial Magnetic Stimulation Reveals Temporal Dynamics of Bilateral Corticomotor Excitability During Response Inhibition. BIORXIV/2022/507942