- E-postian.mills@uib.no
- BesøksadresseHaukeland universitetssykehus, Laboratoriebygget5009 Bergen
- PostadressePostboks 78045020 Bergen
Vitenskapelig artikkel
- (2022). The relationship between lipoprotein A and other lipids with prostate cancer risk: A multivariable Mendelian randomisation study. PLoS Medicine.
- (2022). Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score. Prostate Cancer and Prostatic Diseases. 755-761.
- (2022). Low Blood Levels of LRG1 Before Radical Prostatectomy Identify Patients with High Risk of Progression to Castration-resistant Prostate Cancer. European Urology Open Science. 68-75.
- (2022). Hyperpolarised <sup>13</sup>C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer. Nature Communications. 12 sider.
- (2022). A non-coding RNA balancing act: miR-346-induced DNA damage is limited by the long non-coding RNA NORAD in prostate cancer. Molecular Cancer. 22 sider.
- (2021). Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse. Nature Communications.
- (2021). Polygenic hazard score is associated with prostate cancer in multi-ethnic populations. Nature Communications.
- (2021). Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24. Prostate Cancer and Prostatic Diseases.
- (2021). Modulating the unfolded protein response with ONC201 to impact on radiation response in prostate cancer cells. Scientific Reports.
- (2021). CaMKK2 facilitates Golgi-associated vesicle trafficking to sustain cancer cell proliferation. Cell Death & Disease. 1-12.
- (2020). Sjögren syndrome/scleroderma autoantigen 1 is a direct Tankyrase binding partner in cancer cells. Communications Biology. 11 sider.
- (2020). Methodology for the at-home collection of urine samples for prostate cancer detection. BioTechniques. 65-73.
- (2020). Inhibition of O-GlcNAc transferase renders prostate cancer cells dependent on CDK9. Molecular Cancer Research. 1512-1521.
- (2020). Inhibition of O-GlcNAc transferase activates tumor-suppressor gene expression in tamoxifen-resistant breast cancer cells. Scientific Reports. 1-10.
- (2020). Identification and Validation of Leucine-rich alpha-2-glycoprotein 1 as a Noninvasive Biomarker for Improved Precision in Prostate Cancer Risk Stratification. European Urology Open Science. 51-61.
- (2020). African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer. International Journal of Cancer.
- (2019). The β2-adrenergic receptor is a molecular switch for neuroendocrine transdifferentiation of prostate cancer cells. Molecular Cancer Research. 2154-2168.
- (2019). Low expression of miR-424-3p is highly correlated with clinical failure in prostate cancer. Scientific Reports. 1-10.
- (2019). IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling. Nature Communications. 1-12.
- (2019). High OGT activity is essential for MYC-driven proliferation of prostate cancer cells. Theranostics. 2183-2197.
- (2019). Drivers of AR indifferent anti-androgen resistance in prostate cancer cells. Scientific Reports. 1-11.
- (2019). CDK9 Inhibition Induces a Metabolic Switch that Renders Prostate Cancer Cells Dependent on Fatty Acid Oxidation. Neoplasia. 713-720.
- (2019). A four‐group urine risk classifier for predicting outcomes in patients with prostate cancer. BJU International. 609-620.
- (2018). Validation of a Metastatic Assay using biopsies to improve risk stratification in patients with prostate cancer treated with radical radiation therapy. Annals of Oncology. 215-222.
- (2018). Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts. The BMJ. 1-7.
- (2018). Identification of shared genetic variants between schizophrenia and lung cancer. Scientific Reports. 1-8.
- (2018). Genetic factors influencing prostate cancer risk in Norwegian men. The Prostate. 186-192.
- (2017). c-Myc antagonises the transcriptional activity of the androgen receptor in prostate cancer affecting key gene networks. EBioMedicine. 83-93.
- (2017). The cancer-associated cell migration protein TSPAN1 is under control of androgens and its upregulation increases prostate cancer cell migration. Scientific Reports.
- (2017). Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer. Nature Communications.
- (2017). Molecular subgroup of primary prostate cancer presenting with metastatic biology. European Urology. 509-518.
- (2017). Lipid degradation promotes prostate cancer cell survival. OncoTarget. 38264-38275.
- (2017). Dual transcriptome of the immediate neutrophil and Candida albicans interplay. BMC Genomics. 696.
- (2017). Correction to: Dual transcriptome of the immediate neutrophil and Candida albicans interplay. BMC Genomics. 863.
- (2017). Bromodomain-containing proteins in prostate cancer. Molecular and Cellular Endocrinology. 31-40.
- (2017). Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer. BMC Genomics. 1-11.
- (2017). Androgen receptor deregulation drives bromodomain-mediated chromatin alterations in prostate cancer. Cell reports. 2045-2059.
- (2016). Using the fluorescent properties of STO-609 as a tool to assist structure-function analyses of recombinant CaMKK2. Biochemical and Biophysical Research Communications - BBRC. 102-107.
- (2016). The Early Effects of Rapid Androgen Deprivation on Human Prostate Cancer. European Urology. 214-218.
- (2016). Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study. PLoS Medicine.
- (2016). Mapping Protein-DNA Interactions Using ChIP-exo and Illumina-Based Sequencing. Methods in molecular biology. 119-137.
- (2016). Inhibition of O-GlcNAc transferase activity reprograms prostate cancer cell metabolism. OncoTarget. 12464-12476.
- (2016). HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer. OncoTarget. 74734-74746.
- (2016). Glycosylation is an androgen-regulated process essential for prostate cancer cell viability. EBioMedicine. 103-116.
- (2016). Gene regulatory mechanisms underpinning prostate cancer susceptibility. Nature Genetics. 387-397.
- (2016). Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli. Data in Brief. 733-740.
- (2016). Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target. Journal of the National Cancer Institute.
- (2016). Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells. Epigenetics & Chromatin.
- (2016). Cell cycle-coupled expansion of AR activity promotes cancer progression. Oncogene. 1655-1668.
- (2015). UAP1 is overexpressed in prostate cancer and is protective against inhibitors of N-linked glycosylation. Oncogene. 3744-3750.
- (2015). The androgen receptor controls expression of the cancerassociated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer. OncoTarget. 34358-34374.
- (2015). Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment. PLOS ONE.
- (2015). Salt-inducible kinase 2 regulates mitotic progression and transcription in prostate cancer. Molecular Cancer Research. 620-635.
- (2015). Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer. OncoTarget. 12587-12602.
- (2015). Macroautophagic cargo sequestration assays. Methods. 25-36.
- (2015). Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study. EBioMedicine. 1133-1144.
- (2015). Glucocorticoid receptor and Klf4 co-regulate anti-inflammatory genes in keratinocytes. Molecular and Cellular Endocrinology. 281-289.
- (2015). Genetic sharing with cardiovascular disease risk factors and diabetes reveals novel bone mineral density loci. PLOS ONE.
- (2015). Divergent androgen regulation of unfolded protein response pathways drives prostate cancer. EMBO Molecular Medicine. 788-801.
- (2015). Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs. Experimental Cell Research. 21-38.
- (2015). Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms. PLOS ONE.
- (2015). A differential protein solubility approach for the depletion of highly abundant proteins in plasma using ammonium sulfate. The Analyst. 8109-8117.
- (2014). The Molecular Signature of the Stroma Response in Prostate Cancer-Induced Osteoblastic Bone Metastasis Highlights Expansion of Hematopoietic and Prostate Epithelial Stem Cell Niches. PLOS ONE. 32 sider.
- (2014). The ETS family member GABPα modulates androgen receptor signalling and mediates an aggressive phenotype in prostate cancer. Nucleic Acids Research (NAR). 6256-6269.
- (2014). Studying N-linked glycosylation of receptor tyrosine kinases. Methods in molecular biology. 103-109.
- (2014). Shared common variants in prostate cancer and blood lipids. International Journal of Epidemiology. 1205-1214.
- (2014). Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer. EMBO Journal. 1365-1382.
- (2014). Meta-analysis of prostate cancer gene expression data identifies a novel discriminatory signature enriched for glycosylating enzymes. BMC Medical Genomics. 513.
- (2014). HES6 drives a critical AR transcriptional programme to induce castration‐resistant prostate cancer through activation of an E2F1‐mediated cell cycle network. EMBO Molecular Medicine. 651-661.
- (2014). Endosomal signalling and oncogenesis. Methods in Enzymology. 179-200.
- (2014). Androgen-regulated metabolism and biosynthesis in prostate cancer. Endocrine-Related Cancer. T57-T66.
- (2013). The Mitochondrial and Autosomal Mutation Landscapes of Prostate Cancer. European Urology. 702-708.
- (2013). The Androgen Receptor Induces a Distinct Transcriptional Program in Castration-Resistant Prostate Cancer in Man. Cancer Cell. 35-47.
- (2013). O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells. Cancer Research.
- (2013). N-Linked Glycosylation Supports Cross-Talk between Receptor Tyrosine Kinases and Androgen Receptor. PLOS ONE. 10 sider.
- (2013). Modulation of intracellular calcium homeostasis blocks autophagosome formation. Autophagy. 1475-1490.
- (2013). Exome Sequencing of Prostate Cancer Supports the Hypothesis of Independent Tumour Origins. European Urology. 347-353.
- (2013). Disseminated tumor cells and their prognostic significance in non-metastatic prostate cancer patients. International Journal of Cancer. 149-155.
- (2012). PIAS1 Is Increased in Human Prostate Cancer and Enhances Proliferation through Inhibition of p21. American Journal of Pathology. 2097-2107.
- (2012). Molecular Subtyping of Primary Prostate Cancer Reveals Specific and Shared Target Genes of Different ETS Rearrangements. Neoplasia. 600-+.
- (2012). Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 11252-11257.
- (2012). ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth. Journal of Clinical Investigation. 4621-4634.
- (2011). The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis. EMBO Journal. 2719-2733.
- (2011). Principles for the post-GWAS functional characterization of cancer risk loci. Nature Genetics. 513-518.
- (2011). Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1. EMBO Journal. 3019-3027.
- (2010). Taking Risks with Translational Research. Science Translational Medicine. 4 sider.
Vitenskapelig foredrag
- (2013). Molecular and Structural Characterization of Sjögren syndrome/scleroderma autoantigen 1, a new binding partner of Tankyrase regulated by the oncogene c-Myc.
Leder
- (2016). Maintaining a Healthy Balance: Targeting TERT to Stem Benign Prostatic Hyperplasia. European Urology. 555-556.
- (2015). Molecular subtyping of prostate cancer: a partnership model. European Urology. 568-569.
- (2011). Bridging the gaps: From risk loci via non-coding RNAs to gene networks and prostate cancer phenotypes. Cell Cycle. 4204-4204.
Short communication
- (2016). Pleiotropic analysis of lung cancer and blood triglycerides. Journal of the National Cancer Institute. 1-4.
Sammendrag/abstract
- (2012). Androgen Receptor Affects Glycosylation Pathways to Alter Growth Factor Receptor Signalling. European Journal of Cancer. S72-S73.
Poster
- (2017). O-GlcNAc transferase inhibition in breast cancer cells .
- (2016). Inhibition of O-GlcNAc transferase in breast cancer cells .
- (2016). Inhibition of O-GlcNAc transferase in breast cancer cells.
- (2014). Metabolic and transcriptomic profiling of cancer cells treated with O-linked N-acetylglucosamine transferase inhibitor (STO45849).
Errata
- (2022). Author Correction: Hyperpolarised <sup>13</sup>C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer (Nature Communications, (2022), 13, 1, (466), 10.1038/s41467-022-28069-2). Nature Communications.
- (2020). Correction to: Human-Based Exposure Levels of Perfluoroalkyl Acids May Induce Harmful Effects to Health by Disrupting Major Components of Androgen Receptor Signalling In Vitro (Exposure and Health, (2020), 12, 3, (527-538), 10.1007/s12403-019-00318-8). Exposure and Health. 929.
- (2017). Erratum: Dual transcriptome of the immediate neutrophil and Candida albicans interplay. [BMC Genomics. 18, (2017) (696)] DOI: 10.1186/s12864-017-4097-4. BMC Genomics. 1-21.
- (2017). Corrigendum to "Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study" [EBioMedicine 2 (9) (2015) 1133-1144] (S2352396415300712) (10.1016/j.ebiom.2015.07.017)). EBioMedicine. 238-238.
- (2015). Correction: Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms. PLOS ONE.
Vitenskapelig oversiktsartikkel/review
- (2021). Vascular normalisation as the stepping stone into tumour microenvironment transformation. British Journal of Cancer. 324-336.
- (2021). The Interplay Between Prostate Cancer Genomics, Metabolism, and the Epigenome: Perspectives and Future Prospects. Frontiers in Oncology.
- (2017). The importance of DNA methylation in prostate cancer development. Journal of Steroid Biochemistry and Molecular Biology. 1-15.
- (2016). The role of glycans in the development and progression of prostate cancer. Nature reviews. Urology. 324-333.
- (2016). CTCF modulates Estrogen Receptor function through specific chromatin and nuclear matrix interactions. Nucleic Acids Research (NAR). 10588-10602.
- (2014). Maintaining and reprogramming genomic androgen receptor activity in prostate cancer. Nature Reviews Cancer. 187-198.
- (2014). HOXB13, RFX6 and prostate cancer risk. Nature Genetics. 94-95.
- (2012). Nuclear translocation and functions of growth factor receptors. Seminars in Cell and Developmental Biology. 165-171.
- (2012). Chromatin binding by the androgen receptor in prostate cancer. Molecular and Cellular Endocrinology. 44-51.