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JON SKORVEs bilde

JON SKORVE

Emeritus
  • E-postjon.skorve@uib.no
  • Besøksadresse
    Haukeland universitetssykehus, Laboratoriebygget
    5009 Bergen
  • Postadresse
    Postboks 7804
    5020 Bergen
Vitenskapelig artikkel
  • Vis forfatter(e) (2021). Plasma 3-hydroxyisobutyrate (3-HIB) and methylmalonic acid (MMA) are markers of hepatic mitochondrial fatty acid oxidation in male Wistar rats. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 10 sider.
  • Vis forfatter(e) (2021). Changes in lipoprotein particle subclasses, standard lipids, and apolipoproteins after supplementation with n-3 or n-6 PUFAs in abdominal obesity: A randomized double-blind crossover study. Clinical Nutrition. 2556-2575.
  • Vis forfatter(e) (2020). The PPAR pan-agonist tetradecylthioacetic acid promotes redistribution of plasma cholesterol towards large HDL. PLOS ONE. 1-21.
  • Vis forfatter(e) (2020). Increased fatty acid oxidation and mitochondrial proliferation in liver are associated with increased plasma kynurenine metabolites and nicotinamide levels in normolipidemic and carnitine-depleted rats. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1-8.
  • Vis forfatter(e) (2020). Hepatic steatosis induced in C57BL/6 mice by a non-ß oxidizable fatty acid analogue is associated with reduced plasma kynurenine metabolites and a modified hepatic NAD+/NADH ratio. Lipids in Health and Disease. 1-10.
  • Vis forfatter(e) (2019). A mitochondria-targeted fatty acid analogue influences hepatic glucose metabolism and reduces the plasma insulin/glucose ratio in male Wistar rats. PLOS ONE. 1-17.
  • Vis forfatter(e) (2018). Associations between fatty acid oxidation, hepatic mitochondrial function, and plasma acylcarnitine levels in mice. Nutrition & Metabolism. 1-13.
  • Vis forfatter(e) (2016). The molecular structure of thio-ether fatty acids influences PPAR-dependent regulation of lipid metabolism. Bioorganic & Medicinal Chemistry. 1191-1203.
  • Vis forfatter(e) (2016). Tetradecylthiopropionic acid induces hepatic mitochondrial dysfunction and steatosis, accompanied by increased plasma homocysteine in mice. Lipids in Health and Disease. 16 sider.
  • Vis forfatter(e) (2015). Three differently generated salmon protein hydrolysates reveal opposite effects on hepatic lipid metabolism in mice fed a high-fat diet. Food Chemistry. 101-110.
  • Vis forfatter(e) (2015). Fish oil and krill oil differentially modify the liver and brain lipidome when fed to mice. Lipids in Health and Disease.
  • Vis forfatter(e) (2015). A protein extract from chicken reduces plasma homocysteine in rats. Nutrients. 4498-4511.
  • Vis forfatter(e) (2014). Hypolipidemic effect of dietary water-soluble protein extract from chicken: impact on genes regulating hepatic lipid and bile acid metabolism. European Journal of Nutrition. 193-204.
  • Vis forfatter(e) (2014). Hypolipidemic effect of dietary water-soluble protein extract from chicken: impact on genes regulating hepatic lipid and bile acid metabolism. European Journal of Nutrition. 193-204.
  • Vis forfatter(e) (2014). High consumption of farmed salmon does not disrupt the steady state of persistent organic pollutants (POP) in human plasma and adipose tissue. Journal of Toxicology and Environmental Health, Part A. 1229-1250.
  • Vis forfatter(e) (2014). Fish oil and krill oil supplementations differentially regulate lipid catabolic and synthetic pathways in mice. Nutrition & Metabolism.
  • Vis forfatter(e) (2014). A salmon protein hydrolysate exerts lipid-independent anti-atherosclerotic activity in apoE-deficient mice. PLOS ONE.
  • Vis forfatter(e) (2013). Krill protein hydrolysate reduces plasma triacylglycerol level with concurrent increase in plasma bile acid level and hepatic fatty acid catabolism in high-fat fed mice. The Functional Foods in Health and Disease (FFHD). 428-440.
  • Vis forfatter(e) (2013). A fish protein hydrolysate alters fatty acid composition in liver and adipose tissue and increases plasma carnitine levels in a mouse model of chronic inflammation. Lipids in Health and Disease. 11 sider.
  • Vis forfatter(e) (2012). Krill powder increases liver lipid catabolism and reduces glucose mobilization in tumor necrosis factor-alpha transgenic mice fed a high-fat diet. Metabolism: Clinical and Experimental. 1461-1472.
  • Vis forfatter(e) (2011). Synthesis of novel PPARα/γ dual agonists as potential drugs for the treatment of the metabolic syndrome and diabetes type II designed using a new de novo design program protobuild. Organic and biomolecular chemistry. 1169-1188.
  • Vis forfatter(e) (2011). Salmon diet in patients with active ulcerative colitis reduced the simple clinical colitis activity index and increased the anti-infl ammatory fatty acid index – a pilot study. Scandinavian Journal of Clinical and Laboratory Investigation. 68-73.
  • Vis forfatter(e) (2011). Anti-inflammatory and hypolipidemic effects of the modified fatty acid tetradecylthioacetic acid in psoriasis -- a pilot study. Scandinavian Journal of Clinical and Laboratory Investigation. 269-273.
  • Vis forfatter(e) (2010). Novel phospholipid analogues of pan-PPAR activator tetradecylthioacetic acid are more PPARα selective. Bioorganic & Medicinal Chemistry Letters. 1252-1255 .
  • Vis forfatter(e) (2009). Trans-10, cis-12-conjugated linoleic acid reduces the hepatic triacylglycerol content and the leptin mRNA level in adipose tissue in obese Zucker fa/fa rats. British Journal of Nutrition. 803-815.
  • Vis forfatter(e) (2009). Trans-10, cis-12-conjugated linoleic acid reduces the hepatic triacylglycerol content and the leptin mRNA level in adipose tissue in obese Zucker fa/fa rats. British Journal of Nutrition. 803-815.
  • Vis forfatter(e) (2009). Tetradecylthioacetic acid attenuates dyslipidaemia in male patients with type 2 diabetes mellitus, possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidation. Diabetes, obesity and metabolism. 304-314.
  • Vis forfatter(e) (2009). Synthesis and Analysis of Novel Glycerolipids for the Treatment of Metabolic Syndrome. Journal of Medicinal Chemistry. 1172-1179.
  • Vis forfatter(e) (2009). Dietary supplementation of tetradecylthioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed on high-fat diets. Diabetes, obesity and metabolism. 1034-1049.
  • Vis forfatter(e) (2008). Pharmacology and safety of tetradecylthioacetic acid (TTA): phase-1 study. Journal of Cardiovascular Pharmacology. 410-417.
  • Vis forfatter(e) (2006). Thia fatty acids with the sulfur atom in even or odd positions have opposite effects on fatty acid catabolism. Lipids. 169-177.
  • Vis forfatter(e) (2006). Phospholipid molecular species, beta-oxidation, desaturation and elongation of fatty acids in Atlantic salmon hepatocytes: effects of temperature and 3-thia fatty acids. Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology. 68-80.
  • Vis forfatter(e) (2006). Phospholipid molecular species, beta-oxidation, desaturation and elongation of fatty acids in Atlantic salmon hepatocytes: Effects of temperature and 3-thia fatty acids. Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology. 68-80.
  • Vis forfatter(e) (2005). The metabolic syndrome and the hepatic fatty acid drainage hypothesis. Biochimie. 15-20.
  • Vis forfatter(e) (2005). The metabolic effects of thia fatty acids in rat liver depend on the position of the sulfur atom. Chemico-Biological Interactions. 71-81.
  • Vis forfatter(e) (2005). Influence of high content of dietary soybean oil on quality of large fresh, smoked and frozen Atlantic salmon (Salmo salar). Aquaculture International. 217-231.
  • Vis forfatter(e) (2004). Lipid-lowering and anti-inflammatory effects of tetradecylthioacetic acid in HIV-infected patients on highly active antiretroviral therapy. European Journal of Clinical Investigation. 709-715.
  • Vis forfatter(e) (2004). Effects of 3-thia fatty acids on feed intake,growth, tissue fatty acid composition, beta-oxidation and Na,K-ATPase activity in Atlantic salmon. ?. 657-668.
  • Vis forfatter(e) (1995). Effects of non-beta-oxidizable sulfur-substituted fatty acid analogues on synthesis and secretion of triacylglycerol and cholesterol in cultured rat hepatocytes. Lipids. 987-994.
  • Vis forfatter(e) (1995). Acute modulation of rat hepatic lipid metabolism by sulphur-substituted fatty acid analogues. Biochemical Pharmacology. 1013-1022.
  • Vis forfatter(e) (1993). The hypotriglyceridemic effect of eicosapentaenoic acid in rats is reflected in increased mitochondrial fatty acid oxidation followed by diminished lipogenesis. Lipids. 683-690.
  • Vis forfatter(e) (1990). Effect of 3- and 4-thia-substituted fatty acids on glycerolipid metabolism and mitochondrial beta-oxidation in rat liver. Biochemical Pharmacology. 2005-2012.
  • Vis forfatter(e) (1981). Variation in microsomal subfractions obtained from normal animal tissues and transformed cells following cell disruption by nitrogen cavitation. Molecular and Cellular Biochemistry. 177-183.
Rapport
  • Vis forfatter(e) (2002). Muscle fat content and fatty acid composition of Atlantic salmon fed fish oil or soybean oil diet. (Fish used in diets for middel-aged overweight women). 24. 24. .
  • Vis forfatter(e) (2002). Muscle fat content and fatty acid composition of Atlantic salmon fed fish oil or soybean oil diet (Fish used in healthy student trial). 25. 25. .
Vitenskapelig foredrag
  • Vis forfatter(e) (2020). Low 3-hydroxyisobutyrate (3-HIB) and high methylmalonic acid (MMA) levels in plasma reflect increased hepatic fatty acid oxidation.
  • Vis forfatter(e) (2004). Laks med ulik fettsyreprofil, effekter på human ernæring og helse.
  • Vis forfatter(e) (2004). A high intake of salmon with different fatty acid profiles - effects on human nutrition and health.
Doktorgradsavhandling
  • Vis forfatter(e) (1994). Hypolipemic fatty acid analogues. Effect on lipid metabolism in rat liver (dr. med).
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
  • Vis forfatter(e) (1982). Differences among microsomal subfractions in normal and transformed cells obtained after cell disruption by nitrogen cavitation. 6 sider.
Poster
  • Vis forfatter(e) (2004). Incorporation and wash-out of conjugated linoleic acid (CLA) and tetradecylthioacetic acid (TTA) in muscle of market sized salmon.
  • Vis forfatter(e) (2004). Inclusion of the isoflavones genistein and daidzein in diets for salmon- effects on product quality.
Fagartikkel
  • Vis forfatter(e) (2004). A high intake of salmon with different fatty acid profiles - effects on human nutrition and health. ?.

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